ライフサイエンスコーパス: T-cell number

1 g animals, despite significant reductions in T cell number.

2 tive cell death prevents further increase in T cell number.

3 -2-mediated control of memory phenotype CD8+ T cell number.

4 and it was accompanied by reduced regulatory T cell number.

5 ice showed a 2- to 3-fold increase in memory T cell number.

6 asis by counteracting transient increases in T-cell number.

7 s were negatively correlated with regulatory T cell numbers.

8 rely diminished mucosal-associated invariant T cell numbers.

9 node) displayed no such increases in CD8(+) T cell numbers.

10 immune responsiveness or T reg and effector T cell numbers.

11 ymic output, potentially reducing peripheral T cell numbers.

12 tween naive, memory, and Foxp3(+) regulatory T cell numbers.

13 tantly decreased inflammatory and regulatory T cell numbers.

14 ed in Tbx21(-/-) mice by reducing regulatory T cell numbers.

15 fication of cytokine profiles and regulatory T cell numbers.

16 ere cytokine secretion levels and regulatory T cell numbers.

17 otype and a selective decrease in regulatory T cell numbers.

18 (DN1) stage, leading to decreased peripheral T cell numbers.

19 ollowed by an equally extensive reduction in T cell numbers.

20 tion was accompanied by a decrease in NK and T cell numbers.

21 substantial than the reduction of total CD4 T cell numbers.

22 This resulted in a 1400-fold increase in T cell numbers.

23 moter display a 10-20-fold increase in total T cell numbers.

24 during persistence, in contrast to declining T cell numbers.

25 iated contraction and do not increase memory T cell numbers.

26 e can enhance NK cell and tumor-specific CD8 T cell numbers.

27 ions between LLP2A signal and macrophage and T cell numbers.

28 in mice results in diminished peripheral CD8 T cell numbers.

29 ports, did not lead to an increase in memory T cell numbers.

30 it did not alter conventional CD4(+)Foxp3(-) T cell numbers.

31 gen-presenting capacity of DCs and increased T-cell numbers.

32 al enumeration of total and antigen-specific T-cell numbers.

33 r peripheral deletion to maintain peripheral T-cell numbers.

34 rease in circulating CD4(+) T-cell and naive T-cell numbers.

35 the HIV-1-controllers with diminished CD4(+)T-cell numbers.

36 e with BCG in inducing Ag85B-specific CD4(+) T-cell numbers.

37 with a marked decrease in splenic gammadelta T-cell numbers.

38 elimination of the latter decreasing CD4(+) T-cell numbers.

39 D, with no significant differences in CLA(-) T-cell numbers.

40 natural killer, T helper 17, and regulatory T-cell numbers.

41 infections, despite normal peripheral CD4(+) T-cell numbers.

42 lated with ~500% increase in effector CD8(+) T-cell numbers.

43 eased circulating CD25(+) T cells and CD4(+) T-cell numbers.

44 oire formation, receptor editing, and B- and T-cell numbers.

45 ry encompassed the recovery of normal CD4(+) T cell numbers, a low ratio of effector to central memor

46 31 induces profound reduction of peripheral T cell numbers after oral dosage and confers pronounced

47 4+ T-cell numbers were lower than naive CD8+ T-cell numbers; after HAART, a greater increase in naive

48 in a marked relative increase in regulatory T-cell numbers among the CD4 T-cell subset of the challe

49 ally in T cells led to a strong reduction in T cell number and a shift toward the effector/memory phe

50 correlated with antitumor efficacy, whereas T cell number and cytokine profile were not.

51 ne the effect of gammaherpesvirus latency on T cell number and differentiation during subsequent hete

52 Loss of T cell number and function during HIV infection or secon

53 e can be modulated by preexisting memory CD8 T cell number and the intensity of inflammation during r

54 Thus, OX40 signals regulate T cell number and viability through the NF-kappaB1 pathw

55 70% reduction in activated CD4(+) and CD8(+) T cell numbers and 20-50% reductions in IFN-gamma-produc

56 Absence of CD18 led to diminished CD4+CD25+ T cell numbers and affected both thymic and peripheral d

57 After one or two inoculations of MVA, the T cell numbers and antibody titers equaled or exceeded t

58 led clodronate liposomes reduced both NK and T cell numbers and attenuated weight loss.

59 y to LNG-treated mice at 1 dpi restored lung T cell numbers and chlamydial burden at 12 dpi to levels

60 T cells resulted in decreased peak donor CD8 T cell numbers and decreased CTL effector function due t

61 matically increased Vbeta14(+) thymocyte and T cell numbers and decreased numbers of cells expressing

62 revealed a positive association between CD8 T cell numbers and decreased proinflammatory function of

63 iency in T cells led to decreased peripheral T cell numbers and defective homeostatic proliferation,

64 slow and causes a gradual increase in total T cell numbers and differentiation into cells with featu

65 -/-) mice display a slight reduction in CD8+ T cell numbers and do not effectively clear a pulmonary

66 er, viral peptide-specific CD4(+) and CD8(+) T cell numbers and effector cell development were signif

67 nt viral infection erodes virus-specific CD8 T cell numbers and effector function, with a concomitant

68 ession on hematopoietic cells inhibited CD8+ T cell numbers and function after LCMV CL-13 infection.

69 Deficiencies in CD8 T cell numbers and function also explained the observati

70 rol the risk of leukemia, we assessed NK and T cell numbers and function in IL-2Rgamma(c)(-/-) mice r

71 Maintenance of CD8(+) T cell numbers and function was dependent on Th cells th

72 rance, but increased IL-22 in vivo decreased T cell numbers and functions in the liver and lymphoid t

73 o partially restore NY-ESO-1-specific CD8(+) T cell numbers and functions, increasing the likelihood

74 Reduced intestinal CD4 T cell numbers and gastrointestinal disease are common f

75 milarly, a significant decrease was noted in T cell numbers and in CD45RB(low) (activated/memory) exp

76 oliferation functions to maintain peripheral T cell numbers and is regulated by cytokines.

77 only 3% of wild-type CD45 activity restored T cell numbers and normal cytotoxic T cell responses.

78 amma (IFN-gamma) expression, increases naive T cell numbers and reduces effector T cell numbers in ad

79 ion with IL-15 boosted antigen-specific CD8+ T cell numbers and resulted in a cooperative effect on t

80 spleens were studied at intervals for B and T cell numbers and subsets and frequency of anti-double-

81 BTLA expression limited gammadelta T cell numbers and sustained normal gammadelta T cell su

82 In this study, we show that reduced T cell numbers and the resulting exaggerated homeostatic

83 T-cell number and function were examined in spleens of T

84 Patients with AT have reduced B- and T-cell numbers and a highly variable immunodeficiency.

85 14-day Ang II infusion increased gammadelta T-cell numbers and activation in the spleen of wild-type

86 with poor prognosis, in addition to reduced T-cell numbers and activity with disease transformation.

87 assays showed accelerated restoration of CD4 T-cell numbers and function.

88 uclear cells was assayed, as were regulatory T-cell numbers and function.

89 ry T-cell regeneration that preserves CD4(+) T-cell numbers and functions above the threshold associa

90 Cs during T-cell priming, whereas allogeneic T-cell numbers and homing in lymphoid and GVHD target or

91 ific HLA multimers to enumerate CMV-specific T-cell numbers and select cells to assess chimerism stat

92 found that Neu5Gc exposure reduced IL-17(+) T-cell numbers and supported differentiation of regulato

93 regression after SCT, absolute WT1(+) CD8(+) T-cell numbers and WT1 expression were studied for each

94 r vaccination, absolute PR1 and WT1(+)CD8(+) T-cell numbers and WT1 expression were studied weekly af

95 in TIL cultures was associated with reduced T cell numbers, and further functional studies demonstra

96 uced lung eosinophilia, changes in pulmonary T cell numbers, and gene and protein expression as well

97 Protein acetylation, regulatory T-cell numbers, and circulating angiogenic factors did n

98 nd bacterial burden, restored splenic CD4(+) T-cell numbers, and increased the frequency of Ehrlichia

99 CD4(+) T-cell frequencies, decreased CD8(+) T-cell numbers, and resolution of CD8(+) T-cell alveolit

100 nd angiogenic capacities of EPCs, angiogenic T-cell numbers, and vascular endothelial growth factor e

101 Significant B and T cell numbers are generated in RAG1(c/c) mice, showing

102 T cell numbers are maintained within narrow ranges in vi

103 how in this article that circulating Vdelta1 T cell numbers are particularly high in patients with HI

104 Competition for these ligands declines when T cell numbers are reduced and causes residual naive T c

105 Furthermore, we find that gammadelta T cells numbers are increased in Itk(-/-) mice, most not

106 ses in inflammation, coagulation, and CD8(+) T-cell numbers are associated with an elevated cardiovas

107 ric PTLD patients, pretreatment EBV-specific T-cell numbers are in the range of healthy controls.

108 Although overall T-cell numbers are normal, both follicular helper and me

109 ete lack of B cells and dramatically reduced T cell numbers, as shown by Rag1(-/-) blastocyst complem

110 hase or protect against the waning of memory T cell numbers at later times after infection.

111 ation and apparent proliferation, with large T cell numbers at the Ag-positive tumor as early as day

112 Further, virus-specific T cell numbers at this site of infection are maintained

113 patients had profound defects in CD4 and CD8 T-cell numbers at diagnosis that did not recover during

114 served a transient increase in CD4+ and CD8+ T-cell numbers at the residual tumor after androgen abla

115 adually exceeded bystander p18-specific CD8+ T-cell numbers, both populations peaked concurrently wit

116 proliferation is suppressed by increases in T cell numbers but not by adoptive transfer of regulator

117 significantly increased Ag-specific effector T cell numbers, but does not result in increased numbers

118 nced IL-2 signals increase peak effector CD8 T cell numbers, but only early IL-2 signals enhance memo

119 e manipulated to improve HIV-specific CD8(+) T cell numbers, but possibly not all functions in vivo.

120 pathogen reencounter increases memory CD8(+) T cell numbers, but the impact on memory CD8(+) T cell d

121 gh negative regulation of natural regulatory T cell numbers by inhibiting the development of MHCII(lo

122 ific regulatory T cells, boosting regulatory T cell numbers by injecting IL-2 immune complexes dampen

123 hosis at 7 days and a 30% decrease in CD4(+) T-cell numbers by 10 days.

124 rs, and strategies to amplify tumor-reactive T-cell numbers by immunization or ex vivo expansion foll

125 Many studies have shown that amplifying T-cell numbers by prime-boost vaccination is most effect

126 ation only had a modest impact on recovering T cell numbers, CD8+ T cells from vaccinated patients co

127 CTLA-4 blockade resulted in lower memory CD8 T cell numbers compared with the DC+early IL-2 treatment

128 This difference in T cell numbers correlated with a reduced capacity of the

129 In RA patients, autoreactive T cell numbers correlated with disease activity and were

130 CD4+ T-cell numbers correlated positively with fasting insuli

131 Upon challenge with Y. pestis, pulmonary T-cell numbers decline in naive mice, whereas immunized

132 however, T cell exit slowed significantly as T cell numbers declined.

133 urthermore, after SHIV-89.6P infection, CD4+ T-cell numbers declined less and survival was longer in

134 By contrast, bystander CD8+ T-cell numbers declined to background numbers following

135 Memory CD8(+) T cell numbers decreased gradually in the absence of CD4

136 Antigen-specific T cell numbers decreased only 2-fold after 6 months.

137 Failure to normalize CD4(+) T-cell numbers despite effective antiretroviral therapy

138 ress to simian AIDS and that maintain stable T-cell numbers despite high levels of viral replication

139 Minimal cDC and CD8 T-cell number differences after low-dose MCMV in D(k) di

140 spontaneous EAE, the number of MBP-specific T cell numbers does not build up gradually in the CNS; i

141 s not evident until 14 days postinjury, with T-cell numbers doubling between 2 and 6 weeks.

142 Lckcre(tg) Grb2-deficient mice show reduced T cell numbers due to impaired negative and positive sel

143 counts and may contribute to the decrease in T cell numbers during late HIV-1 infection.

144 CD4(+) T cell numbers even declined after stimulation by pp65(4

145 T cell numbers expand 20-fold and a majority secretes IL

146 onse to antigen stimulation to confer CD8(+) T cell-number expansion and effector functions against d

147 cell survival and fitness during peripheral T cell-number expansion in response to virus infection.

148 between virus and host that occurs when CD4+ T cell numbers fall below a level that can sustain immun

149 on, E2F1/E2F2 DKO mice do not recover normal T cell numbers following exposure to a sublethal dose of

150 f therapeutic avenues aimed at modulating DN T cell number for the prevention of autoimmune diseases.

151 ent reduction in mean circulating CD25+ CD4+ T cell number, from 83 +/- 16 cells/microl to a nadir of

152 We reported previously that normal T-cell numbers, function, and repertoire developed by 3

153 Although pN-specific T-cell numbers gradually exceeded bystander p18-specific

154 f the transferred T cells, even after stable T cell numbers have been reached, suggests that active c

155 in either CD30 or OX40 alone reduced CD4(+) T cell numbers, however, in mice deficient in both OX40

156 upon reactivation and preexisting memory CD8 T cell number (i.e., primary memory CD8 T cell precursor

157 ulation blockade also reduced virus-specific T-cell numbers, illustrating that sustained interactions

158 icant increases in dendritic cell and CD8(+) T cell number in advanced tumor-bearing mice compared wi

159 es naive T cell numbers and reduces effector T cell numbers in adipose tissue.

160 CD4 T cell numbers in B6.muMT(-/-) spleens were 10% of that

161 in psoriasis pathogenesis, but inflammatory T cell numbers in blood, as well as the relative importa

162 gnificantly increased median B cell, but not T cell numbers in both cohorts, with a trend for increas

163 led to a marked reduction of eosinophil and T cell numbers in bronchoalveolar lavage fluid compared

164 Ibrutinib markedly increased CD4+ and CD8+ T cell numbers in CLL patients.

165 lpha18 leads to a complete restoration of NK T cell numbers in fyn(-/-) mice.

166 In this study, we found that T cell numbers in Grb2(fl/fl) CD4cre(tg) mice were norma

167 to reduced virus titers and increased CD8(+) T cell numbers in high- but not low-pathological infecti

168 Here, we show that the increase in T cell numbers in IL-7 TG mice is most apparent at the l

169 K cells and contraction of CD4(+) and CD8(+) T cell numbers in individual patients in vivo provides s

170 es were profoundly reduced in blood, whereas T cell numbers in lymph nodes and spleen were at or near

171 pression in LMP7(-/-) mice or reduced CD8(+) T cell numbers in MECL-1(-/-) mice.

172 biota also failed to fully expand intestinal T cell numbers in mice.

173 y lymphoid organs, whereas it expanded naive T cell numbers in nonlymphoid tissues; these effects wer

174 well in differences in protective memory CD8 T cell numbers in outbred individuals.

175 We have followed natural killer (NK) T cell numbers in patients with IMD, both by flow cytome

176 l therapy (cART) substantially restores CD4+ T cell numbers in peripheral blood, but the gut compartm

177 During infection, naive T cell numbers in peripheral lymphoid organs increase.

178 CD4(+) T cell numbers in the airways of CRA-challenged abr(-/-)

179 proved lung compliance, and increased CD8(+) T cell numbers in the airways.

180 We observed increases in OVA-specific CD8(+) T cell numbers in the local lung compartments (bronchoal

181 Memory CD8 T cell numbers in the lungs and noninvolved organs 100 d

182 Despite normal T cell numbers in the skin, Cxcr3(-/-) mice exhibited dr

183 pproaches to the therapeutic manipulation of T cell numbers in vivo.

184 In these mice, T-cell number in lymph nodes was reduced by 27%.

185 ed bone resorption by >85% and decreased the T-cell number in periodontal tissues.

186 STC1 had minimal effects, however, on both T-cell number in the glomeruli and interstitium and on c

187 This leads to T-cell numbers in adulthood that are minimally decreased

188 limus resulted in a decrease in host splenic T-cell numbers in anti-CD40L mAb-treated recipients.

189 tment results in enhanced local and regional T-cell numbers in both the skin and SLN.

190 t(W-sh/W-sh) hosts correlated with increased T-cell numbers in lymph nodes, liver, and gastrointestin

191 lted in enhanced thymopoiesis and peripheral T-cell numbers in middle-aged recipients of an allogenei

192 t be acting to preserve the peripheral blood T-cell numbers in patients.

193 reduction in dendritic epidermal gammadelta T-cell numbers in the epidermis, indicating that these p

194 esults in dramatically decreased CD4 and CD8 T-cell numbers in the lamina propria of both small and l

195 were followed by relatively high and stable T-cell numbers in the SIV-infected macaques with a slow-

196 lecule, they have the potential to influence T-cell numbers in the skin through chemokine production

197 been linked to a failure to normalize CD4(+) T-cell numbers in treated human immunodeficiency virus (

198 ERRalpha deficiency reduced activated T-cell numbers in vivo and cytokine production in vitro

199 Sephadex increased T cell numbers (including CD4(+) T cells) and evoked a p

200 uced spleen and lymph node CD4(+) and CD8(+) T cell numbers, including naive, activated, and Foxp3(+)

201 ction with vaccinia virus, dermal gammadelta T cell numbers increased 10-fold in the infected ear and

202 ed FOXP3(lo/-)CD4 T cells while FOXP3(hi)CD4 T cell numbers increased.

203 Mucosal CD3, CD4, and CD8 T-cell numbers increased following infection.

204 Furthermore, CD8+ T-cell numbers increased more than twofold, mainly due t

205 ited T cell reconstitution, decreased memory T cell numbers, increased the relative frequency of Treg

206 0-enhancement of tumor immunity and effector T cell numbers is decreased in middle-aged mice and was

207 ermine whether the quantitative reduction in T-cell numbers is due to an intrinsic T-cell defect or w

208 a is that the age-related rate of decline of T-cell numbers is slower in patients than controls.

209 Although the age-related fall in CD8(+) T-cell numbers is well established, neither the underlyi

210 Although TNF neutralization reduced T cell numbers, its coneutralization with IL-10 unexpect

211 rapy dramatically increased antigen-specific T-cell numbers leading to enhancement in the survival of

212 n-induced cell death, IL-21 sustained CD8(+) T cell numbers long term as a result of increased surviv

213 individuals is often characterized by lower T cell numbers, lower naive/memory T cell ratios, and lo

214 All patients with low CD3(+) T-cell numbers (<500 cells/muL) also had markedly decrea

215 tion and that a physiological increase in DN T cell number may be sufficient to confer resistance to

216 pression (IFN-gamma, STAT-1, granzyme B) and T cell numbers may be due to a reduction in DC-mediated

217 We found that despite normal T cell numbers, mice deficient in the costimulatory mole

218 n the compound knockout, although peripheral T cell numbers mirrored Flt3l(-/-) mice.

219 the precursor B-cell development, low B- and T-cell numbers, normal immunoglobulin gene use, limited

220 s contributed to the low OVA-specific CD8(+) T cell numbers observed during type I infection.

221 erations in cytokine expression, the reduced T-cell numbers observed coincided with diminished T-cell

222 tumor efficacy, without affecting responding T cell number or cytokine profile.

223 ase states that result in deficits in CD4(+) T cell numbers or function, such as may be seen in human

224 ant change in mucosal effector or regulatory T cell numbers or IL-10 mRNA expression.

225 on from diabetes did not result from altered T cell numbers or subset distributions, or regulatory/su

226 elated T-cell expansions do not impair naive T-cell numbers or maintenance of protective responses ag

227 o infection, and did not increase memory CD8 T cell numbers over those observed in wild-type controls

228 a significant increase in thymic and splenic T cell number (p < 0.05; p < 0.01).

229 ects, with significant differences in CLA(+) T-cell numbers (P < .01).

230 ma, demonstrating an increase in circulating T cell numbers, particularly naive (TREC+) T cells.

231 t lesion macrophage-positive area and CD4(+) T-cell number per lesion area, but reduced lesion expres

232 By contrasting Vgamma2Vdelta2 T-cell numbers, phenotype, and T-cell receptor (TCR) rep

233 derived cytokines in serum/plasma), reduced T cell numbers/proliferation, and TH1 skewing.

234 CD8(+) T cell-numbers rapidly expand and then contract after ex

235 We recently showed that blood CD4(+) T-cell numbers rapidly increase after dUCBT, and early C

236 occurs as HIV viremia is suppressed and CD4 T cell numbers recover.

237 lls, but showed no differences in regulatory T-cell numbers relative to patients without IRAEs.

238 plantation in rATG-treated patients, whereas T-cell numbers remained stable in both control groups.

239 ilamentous bacteria (SFB) partially restored T cell numbers, suggesting that SFB and other MMb organi

240 OVA-specific CD8 T cell number, TCR affinity, effector function, and infi

241 D4 T cells is controlled more tightly by CD4 T cell numbers than is CD8 T cell proliferation.

242 taining elevated insulin-specific regulatory T cell numbers that efficiently lowered diabetogenic eff

243 Because this transgene restores NK T cell numbers, the lack of secondary lymphocyte activat

244 apy stimulated significant increases in CD8+ T cell numbers, the number of CD4+ T cells remained unch

245 roliferation does not normally fully restore T-cell numbers, the CD8(+) T-cell pool was completely re

246 We prospectively measured T-cell numbers, thymopoiesis, and T-cell memory in 73 ch

247 , leading to reductions in pathologic DC and T-cell numbers to nonlesional levels; and (3) inhibition

248 Efficient boosting of memory T-cell numbers to protective levels generally requires a

249 thogen exposure, increased pathogen-specific T cell numbers together with altered migratory patterns

250 Although T cell numbers ultimately reached adult levels in the in

251 had a 60-fold increase in CD4(+)IFN-gamma(+) T cell numbers versus control animals at 2 wk post-needl

252 r gene-reporter probe systems for imaging of T cell number was performed, and the hNET/(18)F-MFBG PET

253 The normalization of T cell numbers was due to inhibition of expansion of con

254 iter for all antigens, and decreasing CD4(+) T cell numbers was strongly associated with a decrease i

255 However, cervical CD4+ T-cell number was associated with HSV-2 infection and a

256 T cells, and the increase in tumor-specific T-cell number was due to reduced activation-induced cell

257 The reduction in T-cell number was marked by low expression of the antiap

258 in the percentage of CD4+ and CD8+ cells and T-cell numbers was observed in 48%, 71% and 99% of LTRs.

259 ddition to a significant diminution of naive T-cell numbers, we found impaired development of a diver

260 CD8(+), CD4(+), and gammadelta T cell numbers were also lower in the lungs of PVM-infec

261 Follicular T cell numbers were correlated with the number of B cell

262 -specific CD8(+) T cells, but overall CD8(+) T cell numbers were either unaffected or only mildly inc

263 IL-17+ T cell numbers were higher in patients with extended oli

264 a.c. of TCR-transgenic OT-I mice, and CD8(+) T cell numbers were increased within eyes, suggesting th

265 ficantly protected from infection and CD4(+) T cell numbers were maintained in both the blood and the

266 In contrast, effector CD4(+) T cell numbers were not affected by the individual or co

267 gnificant effects on CD8(+) or CD4(+) memory T cell numbers were observed.

268 tic cells decreased in blood, whereas NK and T cell numbers were only marginally altered during the c

269 Intratumoral gammadelta T cell numbers were positively correlated with advanced

270 he adult Foxn1Delta/Delta thymus, peripheral T cell numbers were reduced only 10-fold.

271 but single-positive thymocyte and peripheral T cell numbers were reduced, reflecting a T cell-autonom

272 rs, whereas total cell, lymphocyte, and CD4+ T cell numbers were reduced.

273 t was normal in both strains, but peripheral T cell numbers were significantly decreased in DKO mice.

274 CD8(+) T cell numbers were significantly increased in eyes of m

275 Total peripheral T cell numbers were significantly reduced in CnA beta(-/

276 ted and cytokine-producing CD4(+) and CD8(+) T cell numbers were still significantly reduced 1 wk lat

277 ma in whom bronchoalveolar lavage regulatory T-cell numbers were also reduced.

278 CD4(+)CD25(+)Foxp3(+) regulatory T-cell numbers were decreased in the spleens of IL-13 KO

279 CD4(+) IL-17-producing T-cell numbers were diminished.

280 ontrol subjects, but decreases in CLA(+) TH1 T-cell numbers were greater in children with AD (17% vs

281 In rats, T-cell numbers were highest between 3 and 7 days postinj

282 IL-10 levels and regulatory T-cell numbers were lower in the intestines of Tpl2(-/-)

283 At 6 months after transplantation, T-cell numbers were lower than before transplantation in

284 At baseline, naive CD4+ T-cell numbers were lower than naive CD8+ T-cell numbers

285 Although their B- and T-cell numbers were normal, they had low regulatory T-ce

286 Naive and central memory T-cell numbers were not affected, nor were anti-tetanus

287 Decreases in DC and T-cell numbers were observed after weeks 1 and 2, respec

288 Both Foxp3(-) and Foxp3(+) pMHCII-specific T-cell numbers were reduced in mice expressing the antig

289 Natural killer cell and CD4 and CD8 T-cell numbers were significantly reduced in treated ani

290 that regardless of transplant type, overall T-cell numbers were similar, although a faster rate of T

291 icient (CD45KO) mice have reduced peripheral T cell numbers where CD8 T cells are underrepresented.

292 reduction of NK cell (90% from baseline) and T-cell numbers whereas CD8 effector memory T-cell popula

293 f thymocytes and slightly reduced peripheral T cell numbers, whereas B cell-specific deletion of FADD

294 ad significantly reduced NK, NKT, and CD8(+) T cell numbers, whereas rIL-15/IL-15Ralpha restored thes

295 ad significantly increased Gag-specific CD8+ T cell numbers, whereas total cell, lymphocyte, and CD4+

296 ial thymus recovery and boosts donor-derived T cell numbers, which correlates with increased adhesion

297 a1(M6) allele developed normal thymocyte and T cell numbers with all expressing Vbeta14.

298 sitive association of CD4(+)CD25(+) FoxP3(+) T cell numbers with allergic sensitization (P = 0.05) an

299 atous lesions, while a correlation of IL-17+ T cell numbers with tenascin C-expressing cells and MMP-

300 e of IL-10 resulted in enhancement of CD8(+) T cell numbers without detectable alterations in the kin