ライフサイエンスコーパス: T-cell receptor beta chain

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1 nes encoding the immunoglobulin heavy chain, T cell receptor beta chain and APOC2, but none has yet b

2 , using mice expressing one of two different T cell receptor beta chains and various MHC alleles, we

3 equencing of the CDR3 variable region of the T cell receptor beta-chain and an algorithm that detecte

4 in the immune response such as those for the T-cell receptor beta-chain and major histocompatibility

5 sequencing to compare the global changes in T cell receptor beta chain complementarity determining r

6 ased on the mutually exclusive expression of T cell receptor beta-chain constant domains 1 and 2 (TRB

7 cilitating cell surface that consists of the T-cell receptor beta-chain disulfide-linked to a previou

8 clones of the factor that interacts with the T-cell receptor beta-chain enhancer motif.

9 onstrated germline configuration of both the T cell receptor beta chain gene and the heavy chain immu

10 blot analysis revealed rearrangement of the T cell receptor beta chain gene, with germline configura

11 oteins and regulate the transcription of the T-cell receptor beta-chain gene.

12 x 129 background) in which a portion of the T-cell receptor-beta chain gene was deleted by gene targ

13 e as monitored by the relative usage of each T-cell receptor beta chain hypervariable region subfamil

14 genes, including beta2-glycoprotein 1, HLA, T cell receptor beta chain, Ig heavy chain, antithrombin

15 Sequencing of the T-cell receptor beta-chains in purified T cells revealed

16 e alphabeta T cell-deficient recipient mice (T cell receptor beta chain knockout mice) experienced al

17 the distal inv(6) breakpoint resides at the T-cell receptor beta chain locus, Tcrb.

18 gamma(+) cells but decreased numbers of NKT (T-cell receptor beta chain + mCD1d tetramer(+)) and CD4(

19 t explant liver, defined at the level of the T-cell receptor beta chain (one epitope/one clone).

20 s was confirmed by Southern blot analysis of T-cell receptor beta chain rearrangement.

21 ed by vector integration site sequencing and T-cell receptor beta-chain rearrangement sequencing, cor

22 s, restricted to H-2Kd, and showed a diverse T cell receptor beta chain repertoire.

23 Analysis of T cell receptor beta chain sequences of IL-4- and TNF-al

24 mavirus (PyV) infection of T-cell-deficient (T-cell receptor beta chain [TCR-beta] -/- or TCR-betaxde

25 es of the variable CDR3 region of human CD4+ T-cell receptor beta chains to infer the statistical pro

26 hnique, the combinatorial diversity of human T-cell receptor beta-chain (TRB locus) was measured in p

27 Here, we sequenced T-cell receptor beta-chain (TRB) gene rearrangements fro

28 d was developed to examine the expression of T cell receptor beta chain variable region 2, 3, 6.1-3,

29 The results demonstrated the expansion of T cell receptor beta chain variable region 3 (two patien

30 rmis, we found that approximately 50% of the T cell receptor beta chain variable region families in e

31 ity is not restricted to a limited number of T cell receptor beta chain variable region families.

32 Cells expressing the T cell receptor beta-chain variable region (Vbeta) 6 con

33 and CD28-), with considerable restriction in T cell receptor beta-chain variable region use.

34 odel are dependent on CD4 T cells that use a T cell receptor-beta chain variable region (Vbeta) reper

35 d variant of its wild-type TCR ligand, human T-cell receptor beta chain variable domain 2.1.

36 In this study, overrepresentation of one T-cell receptor beta chain variable region, TCRBV3, was

37 T cells bearing the T-cell receptor beta chain variable regions 5.1, 5.2, 6.

38 Toxin binding to variable domains of T cell receptor beta chains (Vbeta) leads to massive rel

39 sing the T490A RAG-2 mutant and a functional T cell receptor beta chain, we demonstrate that coupling

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