ライフサイエンスコーパス: T-cell subset

1 s associated with a steady expansion of this T cell subset.

2 lls are a well-characterized CD1d-restricted T cell subset.

3 ne production, and effector function in this T cell subset.

4 n has a genuine costimulatory effect on this T cell subset.

5 partment and a reduction in the CD8alphabeta T cell subset.

6 ted to a resting PD1(+)ICOS(-) CD4(+) memory T cell subset.

7 ade came almost exclusively from this CD8(+) T-cell subset.

8 ential role in the generation of this CD8(+) T-cell subset.

9 sensitive to TEX-mediated effects than other T cell subsets.

10 tion of effector gammadelta versus alphabeta T cell subsets.

11 logical functions of distinct CD1-restricted T cell subsets.

12 ajority of ACT trials utilize unfractionated T cell subsets.

13 mostly distinct compared with other colonic T cell subsets.

14 these regulatory processes in various CD4(+) T cell subsets.

15 ore HIV DNA than CD25(-) FoxP3(-) memory CD4 T cell subsets.

16 nsient yet robust proliferation in all major T cell subsets.

17 including all phenotypic and functional CD4 T cell subsets.

18 e the entire spectrum of memory and effector T cell subsets.

19 stinct phenotypic and functional gamma/delta T cell subsets.

20 for monitoring HIV reservoirs in defined CD4 T cell subsets.

21 ex vivo in CD4(+), CD8(+), and CD4(-)CD8(-) T cell subsets.

22 mote expansion of pathogenic proinflammatory T cell subsets.

23 T cells to alter conventional and regulatory T cell subsets.

24 ession programs expected to define different T cell subsets.

25 ivated, and Foxp3(+)CD25(+)CD4(+) regulatory T cell subsets.

26 e control of specific functions in different T cell subsets.

27 erstood to in part be mediated by effects on T cell subsets.

28 entially regulating gene expression in these T cell subsets.

29 so revealed no defects in the development of T cell subsets.

30 s that are functionally analogous to diverse T cell subsets.

31 undergoes differential methylation in CD8(+) T cell subsets.

32 the ex vivo response to S1P of primary human T cell subsets.

33 ave the capacity to regulate the function of T cell subsets.

34 and S1PR2 governs the migratory behavior of T cell subsets.

35 ecific tumor-infiltrating exhausted-like CD8 T cell subsets.

36 as intermittently detected from various CD4+ T cell subsets.

37 nd preventing its conversion to other CD4(+) T cell subsets.

38 exhibited oligoclonal expansion of specific T cell subsets.

39 ially affect already alloactivated human CD4 T-cell subsets.

40 approach identified at least four different T-cell subsets.

41 wed a high density of both CD4(+) and CD8(+) T-cell subsets.

42 ndependently impacted on multiple B-cell and T-cell subsets.

43 not a result of proportional aberrations of T-cell subsets.

44 NK and altered CXCR3 and PD-1 expression on T-cell subsets.

45 (+)/IFN-gamma(+)/IL-2(-)/TNF-alpha(-) CD8(+) T cells) subsets.

46 function of individually sorted CAR-modified T cell subsets after activation with CD3 and CD28 Abs (C

47 rved decay of the latent HIV-1 cells in both T cell subsets after exposure to each of the latency-rev

48 s, and the latter Nef function protects this T cell subset against apoptosis.

49 and IL-37 limit the induction of particular T cell subsets along with cytokine responses in S. sterc

50 T initiation, cellular immune activation and T-cell subsets also were similar in TB-IRIS patients and

51 een detected in both naive and memory CD4(+) T cell subsets although the frequency of HIV-1 DNA is ty

52 tions was related to an increased regulatory T cell subset and an elevated apoptosis rate of T cells

53 fication of a previously unknown innate-like T cell subset and indicate that T cell hyporesponsivenes

54 were manufactured from defined CD4+ and CD8+ T cell subsets and administered in a defined CD4+:CD8+ c

55 R6(-), and gammadelta27(-)CCR6(+) gammadelta T cell subsets and alphabeta T cells.

56 or entry, which may direct SIV toward CD4(+) T cell subsets and anatomical sites that support viral r

57 e activation and differentiation of specific T cell subsets and antigen-presenting cells, thought to

58 -promoter interactions in rare primary human T cell subsets and coronary artery smooth muscle cells l

59 hrough which glucosamine modulates different T cell subsets and diseases remain unclear.

60 are differentially expressed among different T cell subsets and function alone or in cooperation to m

61 letional roles for Nur77 that differ between T cell subsets and have implications for self-tolerance.

62 ytes play a critical role in polarization of T cell subsets and participate in clearance of transfuse

63 nscription factor Bcl11b is expressed in all T cell subsets and progenitors, starting from the DN2 st

64 s the differentiation of various CD4 and CD8 T cell subsets and provide insights into the underlying

65 between gammadelta27(+) and gammadelta27(-) T cell subsets and provide novel insight on the nonoverl

66 ocess led to the loss of less-differentiated T cell subsets and resulted in impaired cellular persist

67 We explore the prognostic value of distinct T cell subsets and show in two cohorts that Th17 cells a

68 cifically released by different human CD4(+) T cell subsets and started to unveil the potential use o

69 the generation of proinflammatory gammadelta T cell subsets and their impact on pathophysiology.

70 recent advances in our understanding of this T-cell subset and address the potential roles for MR1-re

71 blood cellular markers included %CD38+DR+ of T-cell subsets and %CD14+CD16+ and%CD14(dim)CD16+ monocy

72 ty, and manifest wide variations (i) between T-cell subsets and among individuals and (ii) in T-cell

73 here, integrates the activities of distinct T-cell subsets and by definition is dynamic and responsi

74 act a variety of immune cell types including T-cell subsets and eosinophils.

75 T-cell subsets and immunoglobulin G seropositivity for C

76 and/or enzyme-linked immunosorbent assay in T-cell subsets and PBMCs from patients with asthma and a

77 CD4(+) /CD8(+) T-cell subsets and polyfunctionality were defined using

78 eased the frequency of functional regulatory T-cell subsets and their transcription factors Gata3 and

79 P3-positive Treg cells are a critical helper T cell subset, and dysregulation of Treg generation or f

80 s the functional properties of each expanded T cell subset, and paves the way for a more detailed eva

81 parent cells by reducing the infiltration of T cell subsets, and other inflammatory cells, in the eye

82 ph nodes, bone marrow, CSF, circulating CD4+ T cell subsets, and plasma.

83 more pronounced for CD4 T cells than for CD8 T cell subsets, and was dependent on S1PR2, as shown usi

84 l-associated invariant T (MAIT) cells, other T-cell subsets, and granulocyte mediators in asthmatic p

85 that regulate differentiation of this CD4(+) T cell subset are incompletely understood.

86 oportions of these cells within the CD25(hi) T cell subset are increased in patients with the more se

87 tumors, little is known about how different T cell subsets are affected during blockade.

88 ces in the numbers and functions of specific T cell subsets are key pathogenic derangements in system

89 metabolic programs of functionally distinct T cell subsets are tailored to their immunologic activit

90 In particular, specific gammadelta T-cell subsets are capable of recruiting immunosuppressi

91 ral blood stem cell grafts (naive and memory T-cell subsets, B cells, regulatory T cells, invariant n

92 or (TCR) sequences, enable us to identify 11 T cell subsets based on their molecular and functional p

93 (2016) describe three distinct memory CD8(+) T cell subsets based upon expression of the fractalkine

94 , but challenges exist in manufacturing this T-cell subset because they are rare among circulating ly

95 n the balance between Tregs and conventional T-cell subsets because a larger proportion of flu-specif

96 family direct the differentiation of helper T cell subsets, but their influence on regulatory T cell

97 hat DMF acts on specific memory and effector T cell subsets by limiting their survival, proliferation

98 the immune responses of specific gammadelta T cell subsets by mechanisms that have characteristics o

99 These findings reveal that T cell subsets can synchronize their differentiation sta

100 xpressed CCR5; increases in the magnitude of T-cell subset CCR5 expression were observed with DMPA an

101 itution was demonstrated by normalization of T-cell subsets (CD3(+), CD4(+), and CD8(+)), evidence of

102 ther p70S6K activity is varying among CD4(+) T-cell subsets, cell sorted CD4(+)CD25(hi) regulatory T

103 Among T cell subsets, central Tmem (Tcm) expressed the highest

104 e approaches, we identified two novel CD4(+) T cell subsets characterized by high levels of PD1: Prdm

105 Induction of a T-cell subset coexpressing IL-21 and IFN-gamma might com

106 lyfunctionality analysis of antigen-specific T-cell subsets (COMPASS).

107 eciation for the actual complexity of helper T-cell subsets continues unabated.

108 The drop in T cell subsets correlated with expression of the fractal

109 ranscriptional and cytokine profile of their T cell subset counterparts.

110 T follicular helper (Tfh) cells are a CD4(+) T cell subset critical for long-lived humoral immunity.

111 Adaptive and invariant T-cell subsets, cytokines, mast cells, and basophil medi

112 0) of CD154 expression was calculated for 36 T-cell subsets defined by combinations of T-helper (Th),

113 heral blood (PB) central memory (TCM) CD4(+) T cell subsets designated peripheral T follicular helper

114 has been shown to be important for promoting T cell subset development and function.

115 in a context-dependent manner to accentuate T cell subset development.

116 ly, signaling downstream of PD-1 in purified T cell subsets did not correlate with PD-1 surface expre

117 Notably, other CD8(+)T-cell subsets did not exert a similar effect on overall

118 T cell subsets differ in their metabolic requirements, a

119 CD4(+) T cell subsets differentially support HIV-1 replication.

120 nvolved in maintenance of T cell quiescence, T cell subset differentiation, and memory T cell generat

121 D3 expression seems to confer to the various T cell subsets differing susceptibility to the in vivo t

122 Recent data suggest that CD4(+) T cell subsets display a considerable plasticity.

123 e shift in CD8(+) T cells in PB, BM, and ALN T-cell subsets during the acute phase of SIV infection.

124 linical models, the use of a purified, naive T cell subset enhances persistence and antitumor immunit

125 on infectivity, however, was observed in all T cell subsets examined.

126 These T-cell subsets exhibit different susceptibilities to the

127 g to the IL-17-producing CD27(-) gamma/delta T cell subset exhibiting innate-like features.

128 Both CD8 T cell subsets expanded and expressed markers indicative

129 we show the appearance of a distinct CD4(+) T cell subset expressing IL-4 at an early stage of devel

130 substantial expansion of CD3(+)CD4(-)CD8(-) T-cell subset expressing Vdelta2 TCR was specifically ob

131 To evaluate the CD8(+) T cell subsets, expression of inhibitory receptors, and

132 A new T-cell subset, follicular helper T (TFH) cells, is speci

133 re an antigen-specific, memory phenotype CD8 T-cell subset found in lymphoreplete, unchallenged mice.

134 In random blood samples, phiphilux+T-cell subset frequencies were higher among 14 rejection

135 regulatory and stem cell-like memory CD4(+) T cell subsets from patients with type 1 diabetes and he

136 ugs used after HSCT on resting and activated T-cell subsets from PB but especially from CB.

137 We analyzed CD4(+) helper T-cell subsets from peripheral blood or cerebrospinal fl

138 Blimp1 for homeostatic maintenance of these T cell subsets had not been investigated.

139 Although CD4 T cell subsets have been mapped globally for numerous ep

140 However, new T-cell subsets have not been considered.

141 conv) and regulatory Foxp3(+) (T reg cells) T cell subsets; however, deletion of CTLA-4 on T reg cel

142 comparison to alternative HIV-1-specific CD8 T cell subsets; however, only proportions of IFN-gamma-s

143 Functional analysis of the role of different T-cell subsets identified the Th1 responses as proathero

144 f follicular helper T cells (Tfh) as the key T cell subset in B cell isotype switching, due to their

145 The pathological relevance of this T cell subset in MS remains to be determined.

146 the extent of induction of the inflammatory T cell subset in vitro that mainly drives lesions, but n

147 antly increased in various CD8(+) and CD4(+) T cell subsets in AA patients, including CD8(+) and CD4(

148 against tumor, but the role of human CD4(+) T cell subsets in cancer immunotherapy remains ill-defin

149 We comprehensively characterized CD8 T cell subsets in dengue patients from India and Thailan

150 ) CD38(+) and HLA-DR(-) CD38(+) effector CD8 T cell subsets in dengue patients from India and Thailan

151 ng Th1 cells, represent two major pathogenic T cell subsets in experimental autoimmune encephalomyeli

152 rrogated clonal relationships between CD4(+) T cell subsets in JIA, using high-throughput TCR reperto

153 of monocytes, neutrophils, B lymphocytes and T cell subsets in lymphoid or mucosal sites did not vary

154 r detection of CD3(+)CD4(+) and CD3(+)CD8(+) T cell subsets in murine spleen and tumor.

155 uggest that S1P promotes retention of memory T cell subsets in secondary lymphoid organs, via S1PR2.

156 red from the previously described gammadelta T cell subsets in several aspects, including the degree

157 utant Delta5G virus infected distinct CD4(+) T cell subsets in SLOs and the small intestine, respecti

158 ts suggests an important role for regulatory T cell subsets in the acquisition of natural tolerance.

159 he latter with highly HIV-susceptible CD4(+) T cell subsets in the cervix may provide a mechanism for

160 To better understand the role of CD4 T cell subsets in the clearance of the virus from CNS ti

161 results in alteration of dendritic cell and T cell subsets in the gut as well as loss of antigen-spe

162 gammadelta T lymphocytes, dominant T cell subsets in the intestine, mediate both regulatory

163 cells, as well as CD4(+) and CD44(+)CD62L(-) T cell subsets in the kidney of MRL/lpr Fli1(+/-) mice c

164 nce indicating important roles for different T cell subsets in the maintenance of CNS homeostasis.

165 is, and a marked increase of rare gammadelta T cell subsets in the peripheral blood.

166 We found that conventional and regulatory T cell subsets in the thymus of neonates and young mice

167 otypes that mirror those of polarized helper T cell subsets in their expression of core transcription

168 duction of IL-10-producing regulatory CD4(+) T cell subsets in vivo.

169 T cells subsets in blood, spleen and lymph nodes were de

170 T (iNKT) cells are a potent immunoregulatory T-cell subset in both humans and mice.

171 lta2 T cells) are the predominant gammadelta T-cell subset in human adult peripheral blood.

172 2Vgamma9 T cells are the dominant gammadelta T-cell subset in human peripheral blood.

173 riant T (MAIT) cells are a large innate-like T-cell subset in humans defined by invariant TCR Valpha7

174 CD8(+)CD28(-) T cells represent a pathogenic T-cell subset in SSc and likely play a critical role in

175 e, we have examined IL-2 sensitivity in CD4+ T-cell subsets in 70 individuals with long-standing T1D,

176 -) ) "polar" CD4(+) and CD8(+) and activated T-cell subsets in AA vs atopic dermatitis (AD) and contr

177 T-cell populations and corresponding CD8(+) T-cell subsets in both cutaneous lymphocyte antigen (CLA

178 aneous lymphocyte antigen (CLA)(+) polarized T-cell subsets in children versus adults with atopic der

179 e roles of distinct M. tuberculosis-specific T-cell subsets in control of de novo and latent M. tuber

180 onducted a longitudinal analysis of HIV-1 in T-cell subsets in different tissue compartments from sub

181 etermined the absolute numbers of gammadelta T-cell subsets in patient whole blood and applied a real

182 lymphocyte antigen (CLA)-positive and CLA(-) T-cell subsets in patients with AD and control subjects.

183 versus systemic (CLA(-)) "polar" CD4 and CD8 T-cell subsets in patients with early pediatric AD, adul

184 a study of skin lesions or activated CLA(+) T-cell subsets in peripheral blood.

185 T-cell subsets in T-cell receptor beta knockout mice wer

186 erleukin-2 (IL-2), whereas CD4(+) and CD8(+) T-cell subsets in tissues produced beta-chemokines both

187 ese data hint for a possible role of diverse T-cells subsets in disease pathogenesis and emphasize th

188 A reduction of peripheral T-cell subsets including regulatory T cells was observed

189 However, the individual T cell subsets, including CD8(+), Th1, Th17, and T regul

190 quential differentiation to generate diverse T cell subsets, including major histocompatibility compl

191 However, all T cell subsets, including naive CD4(+) T cells and TH2 c

192 At T0, the frequencies of CD4 T cell subsets, including peripheral T follicular helper

193 demonstrate that SW THY generates all human T cell subsets, including regulatory T cells (Tregs), in

194 We compared the frequencies of T cell subsets, including regulatory T cells, in pregnan

195 sulting in the generation of multiple CD4(+) T-cell subsets, including Th1, Th2, Th9, Th17, Treg, and

196 Various T-cell subsets, including Th2/Th22 cells, are increased

197 es the frequency of infection of this CD4(+) T cell subset, indicating that SAMHD1 is an active restr

198 d HSCs, HSCs plus bulk T cells, or HSCs plus T cell subsets into mice conditioned with low-dose irrad

199 ased MHP was a general phenotype observed in T cell subsets irrespective of prior antigen exposure, a

200 Examination of whether a particular T cell subset is involved in the breach of B cell tolera

201 prove the principle that the Vgamma2Vdelta2 T cell subset is protective against Mycobacterium tuberc

202 studies indicate that tissue localization of T cell subsets is important for both protective immunity

203 developing tools to interrogate FA-uptake by T cell subsets is important for understanding tumor immu

204 cise molecular mediators that govern this in T cell subsets is unknown until now.

205 A novel CMV-induced regulatory-type CD4+ T-cell subset is readily detectable in CMV-infected peop

206 without co-expression of cytokines of other T-cell subsets is essential to better understand their f

207 t CD151 could mark a phenotypically distinct T cell subset, it was not uniformly expressed on T cells

208 ction of human natural killer (NK) cells and T cell subsets limit the applicability of humanized mice

209 a T cells, which were replaced by gammadelta T-cell subsets (mainly Vgamma6(+) gammadelta(low)CCR2(+)

210 T(SCM) reveals both upregulation of various T cell subset markers and preservation of their stem cel

211 ts the view that the dominant Vgamma2Vdelta2 T cell subset may be included in the rational design of

212 oles suggest that targeting GzmB in selected T cell subsets may provide a strategy to control GVHD.

213 This surprising finding implies that T cell subsets may vary in their relative T-cell recepto

214 The study of this T-cell subset may lead to a better understanding on how

215 We postulate that additional MR1-restricted T-cell subsets may play a unique role in defence against

216 ications at the DNA level of antigen-induced T-cell subsets might be predictive of a state of operati

217 luated the in vitro effects of GX15 on human T cell subsets obtained from PBMCs in terms of activatio

218 Specific IgE values, skin prick test, and T-cell subsets of STAT3-HIES patients were comparable wi

219 tified the relative effects of CD4+ and CD8+ T-cell subsets on bone.

220 IgE antibody in vivo in the absence of other T-cell subsets or even when TH2 cell functions were seve

221 rain WR and show that both CD4(+) and CD8(+) T-cell subsets play a role in the blinding eye disease a

222 Our data define an unconventional CD8(+) T-cell subset (polycytotoxic T cells) that is based on a

223 naling, because IL-1beta and IL-23 stimulate T cell subsets producing IL-22, another direct target of

224 Next, we analyzed which CD4 T-cell subset proliferated and how this response was aff

225 he possibility of identifying distinct Foxp3 T cell subsets prompted us to more thoroughly characteri

226 veral different HIV isolates among different T cell subsets, providing a link between the differentia

227 The dominant Vgamma2Vdelta2 T cell subset recognizes phosphoantigen and exists only

228 nuate regulatory but not conventional CD4(+) T-cell subsets [regulatory T cell (Treg) and conventiona

229 lls, including resting and stimulated CD4(+) T-cell subsets, regulatory T cells, CD8(+) T cells, B ce

230 o data are available on whether human CD4(+) T cell subsets release EVs containing different pattern

231 Major T cell subsets remained stable over time; although B cel

232 We found PD-1(+) TRMs were the predominant T-cell subset responsive to anti-PD-1 treatment and sign

233 naive, stem cell memory, and central memory T cell subsets results in superior persistence and antit

234 sion intensity among peripheral and duodenal T-cell subsets revealed varied capacities for mucosal ho

235 Understanding T-cell subset sensitivity to belatacept may identify cel

236 erminal effector versus memory-precursor CD8 T cell subsets showed that, rather than retaining a naiv

237 Such T cell subset-specific differences were also observed fo

238 hi) cells within the tumor-infiltrating CD8+ T cell subset strongly correlated with response to thera

239 e ability to differentiate into other memory T cell subsets, such as central and transitional memory

240 f infiltrating mature DC and effector memory T-cell subsets, suggesting that CRT triggers the activat

241 gs) uptake FA at a higher rate than effector T cell subsets, supporting the role of FA metabolism for

242 m in CCR5-low natural hosts may alter CD4(+) T cell subset targeting compared with that in nonnatural

243 tudy, we investigate the contribution of two T cell subsets, Th17 and follicular helper T (Tfh), to a

244 nse, particularly the contribution of CD4(+) T cell subsets, Th17 and regulatory T cells , in AK is y

245 his study, we identified a unique gammadelta T cell subset that coexpresses high levels of gut-homing

246 l killer T cells (iNKT cell) as a model of a T cell subset that differentiates in response to specifi

247 ow clear that there exists a distinct memory T cell subset that is absent from blood but found within

248 RM precursor cells represent a unique CD8(+) T cell subset that is distinct from the precursors of ci

249 ffect on the development of human Th9, a CD4 T cell subset that is highly associated with asthma, in

250 invariant T (MAIT) cells are a unique innate T cell subset that is necessary for rapid recruitment of

251 describe a novel nonconventional NKp46+ CD3+ T cell subset that is phenotypically and functionally di

252 an IL-10-regulated, colitogenic memory CD4+ T cell subset that is poised to initiate inflammation wh

253 ulatory cells (TFR) are a suppressive CD4(+) T cell subset that migrates to germinal centers (GC) dur

254 lar helper (TFH) cells, a specialized CD4(+) T cell subset that orchestrates B cell differentiation w

255 ed NKT cells comprise an unusual innate-like T cell subset that plays important roles in both bacteri

256 nantly modulates surface receptors on CD4(+) T cell subsets that are not already fully permissive for

257 Immunization generates several memory T cell subsets that differ in their migratory properties

258 s highlights the existence of Ag-experienced T cell subsets that do not rely on PD-1/PD-L1 regulation

259 he mouse thymus produces discrete gammadelta T cell subsets that make either interferon-gamma (IFN-ga

260 ether TL1A promotes the development of other T cell subsets that secrete cytokines to drive allergic

261 the intracellular environment of two CD4(+) T cell subsets that share several requirements for their

262 frey Hill has identified a rare "night fury" T-cell subset that causes much pain with no gain, a find

263 umor effects of a unique human CD4(+) helper T-cell subset that directly recognizes the cytoplasmic t

264 of two dominant but contrasting Vdelta2((+)) T-cell subsets that have divergent transcriptional progr

265 eously study the responsiveness of different T cell subsets, that is, naive, effector, and memory T c

266 strate that AEA suppresses highly pathogenic T cell subsets through CB1-mediated mammalian target of

267 s that CD3 expression levels differ from one T cell subset to another.

268 issue of the JCI, Lee et al. evaluated CD4+ T cell subsets to determine whether certain populations

269 immune activation and loss of trafficking of T cell subsets to niches that sustain their maturation a

270 ied a specific combination of polyfunctional T-cell subsets to pp65 that predicted protection from su

271 onstrates the exclusive gene transfer into a T cell subset upon systemic vector administration openin

272 To investigate hepatic T-cell subsets upon hypercholesterolemia.

273 ous lymphocyte antigen (CLA), on circulating T cell subsets was associated with skin or lymph node me

274 This CD8(+) T-cell subset was characterized by a unique gene signatu

275 homotypic or heterotypic DENV serotypes, and T cell subsets were depleted before the second infection

276 mpared to healthy controls, but other helper T cell subsets were not different.

277 Different memory CD4(+) T cell subsets were then sorted for quantification of ce

278 -3+, cathepsin B+) and inflammatory (CD154+) T-cell subsets were evaluated before and after adding ra

279 y and corneal clouding, indicating that both T-cell subsets were involved in the immunopathological r

280 Cytotoxic responses of T-cell subsets were measured by using flow cytometry.

281 Most (n = 25) T-cell subsets were sensitive to belatacept.

282 tuted by adoptive transfer with CD4+ or CD8+ T-cells subsets were reconstituted in T-cell receptor be

283 (TFs) are key to the development of specific T cell subsets, whether additional transcriptional regul

284 rved a decline in circulating specific B and T cell subsets, which reached their nadir 4-8 hours afte

285 memory stem cells (TSCM) are a unique memory T cell subset with enhanced self-renewal capacity and th

286 vaccination generated two synergistic memory T cell subsets with distinct migratory properties.

287 The differentiation of CD4(+) helper T cell subsets with diverse effector functions is accomp

288 Collectively, these findings identify CD4(+) T cell subsets with properties critical for improving ca

289 differed markedly between cytokine-producing T cell subsets with, gamma interferon (IFN-gamma)- and t

290 latory T-cells (Tregs) comprise a CD4+FOXp3 +T-cell subset with a unique ability to regulate other le

291 nment comprising T-helper-17 (Th17) cells, a T-cell subset with protumorigenic properties.

292 recently described abundant, proinflammatory T-cell subset with unknown roles in pulmonary immunity.

293 Multiple memory CD8(+) T-cell subsets with distinct functional and homing chara

294 trigger selective proliferation of recipient T-cell subsets with variable sensitivity to immunosuppre

295 es are the major human peripheral gammadelta T cell subset, with broad reactivity against stressed hu

296 is affected by the balance of different CD4 T cell subsets, with greater severity occurring when the

297 n profile and role of Cav1 channels in human T-cell subsets, with a focus on TH2 cells.

298 This allows for enumeration of these T cell subsets within immune environments, as well as th

299 e proliferation of a Vdelta2(neg) gammadelta T-cell subset within peripheral blood mononuclear cells

300 animals developed significant changes within T cell subsets without changes in total numbers.