ライフサイエンスコーパス: T-regulatory cell

1 olecule present on a subset of human natural T regulatory cells.

2 of CD8(+) T effector cells to CD4(+)FoxP3(+) T regulatory cells.

3 rinsic, with no detectable effects on Th1 or T regulatory cells.

4 r gut homeostasis and maintenance of colonic T regulatory cells.

5 survival, function, and expansion of type 1 T regulatory cells.

6 suppressor cells, tolerogenic monocytes, and T regulatory cells.

7 nhancing the development of Foxp3(+)-induced T regulatory cells.

8 L-2 induces organ pathology and expansion of T regulatory cells.

9 g dependent and IL-2-nano-APC did not affect T regulatory cells.

10 ntiation, and downregulates the induction of T regulatory cells.

11 of IRIS was not influenced by the levels of T regulatory cells.

12 insic unresponsiveness and the activation of T regulatory cells.

13 e IFN-gamma production by expanding FoxP3(+) T regulatory cells.

14 se transfer is ameliorated by cotransferring T regulatory cells.

15 fector cells while sparing the generation of T regulatory cells.

16 responses to Ag and induce the generation of T regulatory cells.

17 d the number of intratumoral CD4(+) Foxp3(+) T regulatory cells.

18 and IL-10 suggested a role for CD4(+)CD25(+) T regulatory cells.

19 is mediated by both conventional and induced T regulatory cells.

20 gene expression, and reduces MDSCs and tumor T regulatory cells.

21 tial mechanism was reduction in intratumoral T regulatory cells.

22 This profile was not observed for natural T regulatory cells.

23 cytes and in increased thymic and peripheral T regulatory cells.

24 igration of purified CD4(+)CD25(+)CD127(dim) T regulatory cells.

25 ss the endothelial barrier at the expense of T regulatory cells.

26 ctions in differentiated CD4(+) T helper and T regulatory cells.

27 ion, despite a systemic increase in FoxP3(+) T regulatory cells.

28 d no GVHD with expanded donor and host Foxp3 T regulatory cells.

29 t expansion of Th17 cells and a reduction in T regulatory cells.

30 DO1 represents an effective tool to generate T regulatory cells.

31 fferentiation, in particular T-helper 17 and T-regulatory cells.

32 e unique T-cell subset, composed of Foxp3(+) T-regulatory cells.

33 nd increased levels of CD4(+)CD25(+)Foxp3(+) T-regulatory cells.

34 and CD8(+) T-effector cells to CD4(+)CD25(+) T-regulatory cells.

35 d a relative bias toward suppressive Th2 and T-regulatory cells.

36 DAA therapy increased patients' numbers of T-regulatory cells (1.5% +/- 0.18% before therapy vs 2.1

37 APCs, blood-brain barrier permeability, and T regulatory cell activity, respectively.

38 An increase in myeloid and T regulatory cells and a decrease in NK and T cytotoxic

39 PN reduces lamina propria activated and T regulatory cells and also naive and memory B cells.

40 At week 12, increased peripheral-blood T regulatory cells and decreased antigen-specific T cell

41 ntial for the development and maintenance of T regulatory cells and for activation-induced cell death

42 y increased the frequency of thymic Foxp3(+) T regulatory cells and Foxp3(-)FR4(hi)CD73(hi) anergic p

43 f food allergy through induction of IL-10(+) T regulatory cells and indirect stabilization of mast ce

44 Of the cell subsets investigated, T regulatory cells and M0 and M2 macrophages emerged as

45 ity of the vaccine to reduce infiltration of T regulatory cells and myeloid-derived suppressor cells.

46 h factor-beta (proTGFbeta) on the surface of T regulatory cells and platelets; however, whether GARP

47 nd elicited proportionally less expansion of T regulatory cells and reduced pulmonary oedema.

48 This programmed DCs to induce FOXP3(+) T regulatory cells and suppressed production of proinfla

49 evels of SIV DNA to CXCR5(-)CCR7(+) "T zone" T regulatory cells and TFH.

50 on of AhR-KO mice resulted in an increase in T regulatory cells and transforming growth factor beta,

51 increased abundance of TAMs and intratumoral T-regulatory cells and decreased abundance of CD8(+) tum

52 levels of blood- and brain-resident Foxp3(+) T-regulatory cells and display an alteration in the infl

53 bers of myeloid-derived suppressor cells and T-regulatory cells and increased T-helper 1 and 17 respo

54 UMSCs also induced the maturation of T-regulatory cells and led to inflammatory cell death.

55 es revealed higher percentages of CD8(+) and T-regulatory cells and lower percentages of B cells.

56 rogrammed death ligand-1 and accumulation of T-regulatory cells and M2-type macrophages.

57 Comparable elevations of T-regulatory cells and myeloid-derived suppressor cells

58 follows: 1) induction of IL-10 and FOXP3(+) T regulatory cells, and 2) suppression of proinflammator

59 -peptide levels, changes in peripheral blood T regulatory cells, and chimerism.

60 PDL1 and CTLA4, increased tumor-infiltrating T regulatory cells, and decreased natural killer (NK) ce

61 es, including cancer-associated fibroblasts, T regulatory cells, and inflammatory mediators.

62 conversion of CD4+CD25- T cells to CD4+CD25+ T regulatory cells, and KLF10 target gene expression.

63 mokine receptor type 5(+) (CCR5(+)) T cells, T regulatory cells, and T-helper 17 cells were unaltered

64 ole in gut inflammation and the induction of T regulatory cells, and the short chain fatty acids (SCF

65 subpopulations of T cells, such as Th17 and T regulatory cells, and to define their role in SLE.

66 igh-dose allergen exposure models in humans, T regulatory cells are essential in the suppression of T

67 This study tests whether Foxp3(+) T-regulatory cells are responsible in the early phase of

68 states include Th1, Th2, Th17, and Foxp3(+) T regulatory cells, as well as the more recently describ

69 ed the induction and maintenance of Foxp3(+) T regulatory cells, as well as their in vitro suppressiv

70 kines and Chemokines, (vi) Cellular markers (T regulatory cells, B regulatory cells and dendritic cel

71 arthritis through the regulation of the Th17/T-regulatory cell balance and osteoclastogenesis.

72 nistic probes for KLF10-mediated effects and T regulatory cell biology.

73 ction was associated with increased adaptive T regulatory cells but not natural regulatory T cells in

74 GITR expression was highest on T regulatory cells but was also detected on Th1 and LCMV

75 jury by IL-33 correlated with an increase in T regulatory cells but with a decrease in macrophages, d

76 rkhead box P3 (FOXP3) is well-established in T-regulatory cells, but the function of transient FOXP3

77 contributes to the function of CD4(+)CD25(+) T regulatory cells by enhancing immune suppression, both

78 l focus on enhancing the clinical benefit of T-regulatory cells by increasing their number and streng

79 Dominant tolerance imposed by CD4(+)Foxp3(+) T regulatory cells can actively control autoaggressive T

80 We also found increased levels of T regulatory cells (CD25(+)CD127(-)) in the spleen and m

81 ver, infiltrating T cells were predominantly T-regulatory cells (CD25+/Forkhead Box P3 [FoxP3+]).

82 erved an induction of regulatory cells (CD4+ T regulatory cells; CD8+ T suppressor cells) and of T me

83 ficantly reduced lamina propria CD4CD25Foxp3 T regulatory cells compared with chow-fed mice, whereas

84 markedly higher percentage of CD8(+)CD122(+) T regulatory cells compared with wild type, which correl

85 ratumoral T effector cells to CD4(+)FoxP3(+) T regulatory cells, compared with monotherapy.

86 ddressed whether alteration in the levels of T regulatory cells contributed to the development of IRI

87 ter reports that adoptive immunotherapy with T-regulatory cells controls the alloreactivity of conven

88 characterized by increased allergen-specific T regulatory cells, decreased circulating Fel d 1 tetram

89 The epigenetic transmittance of adaptive T regulatory cell deficiency is demonstrated throughout

90 schemes using a Toll-like receptor agonist, T regulatory cell depletion, or the immune modulator B7-

91 ty have been noted to result from defects in T regulatory cell, development and function.

92 ically regulate the acquisition of CD4+CD25+ T regulatory cell differentiation and function, an effec

93 ing pathways critical to T-cell trafficking, T regulatory cell differentiation or suppressor function

94 d FOXP3 induction and inappropriate adaptive T regulatory cell differentiation results in vitro and i

95 4 pathway in DCs and programs them to drive T regulatory cell differentiation.

96 may involve augmentation of TGF-beta-induced T regulatory cell differentiation.

97 head box P3 (Foxp3) locus during the induced T regulatory cell differentiation.

98 nse by augmenting both T-helper-1-driven and T-regulatory-cell-driven inflammatory responses in the l

99 cell subsets (Th1, Th2, Th17, and inducible T-regulatory cells), each of which has specialized funct

100 ding Th2 skewing and reduced IL-10-secreting T regulatory cells, exaggerated with additional allergen

101 ed MV induce immune suppression by promoting T regulatory cell expansion and the demise of antitumor

102 lows overgrowth of Lactobacilli and triggers T regulatory cell expansion in the gut.

103 erapy with tolerogenic donor-specific type 1 T regulatory cells for patients with type 1 diabetes und

104 erance cannot occur in murine models lacking T regulatory cells, for which Foxp3+ is a key marker.

105 lso exhibited higher FoxP3(+) CD25(+) CD4(+) T regulatory cell frequency, FoxP3 expression, and alter

106 imited and important cell populations (e.g., T regulatory cells) from disease conditions or in diseas

107 A number of other gene defects that affect T regulatory cell function also give rise to IPEX-relate

108 The tolerogenic cytokine IL9 promotes T regulatory cell function and allergic airway inflammat

109 e the clinical and experimental evidence for T regulatory cell function in the lung and discuss the e

110 spectrum of genetic defects that compromise T regulatory cell function underlies human disorders of

111 JNK phosphorylation plays a central role in T regulatory cell function with therapeutic implications

112 taining T cell homeostasis as well as normal T regulatory cell function, thereby controlling abnormal

113 or suppressor gene and a master regulator in T regulatory cell function.

114 logical functions, including cardiac growth, T-regulatory cell function, neuronal disorders, muscle d

115 Human CD4+CD25+Foxp3+ T regulatory cells (huTreg) suppress CD4+ T cell-mediate

116 l therapy, patients had increased numbers of T-regulatory cells, IgM+CD21-/low-memory B cells, CD4+CX

117 by other monocyte subsets and enhance CD4(+) T regulatory cell IL-10 expression.

118 were therefore evaluated for CD4(+) T cells, T regulatory cells, IL-17, and supporting cytokines by i

119 shown that CD4(+) T-cells, especially CD4(+) T-regulatory cells, improve wound healing after MI, wher

120 us altering the ratio of donor T effector to T regulatory cells in favor of reducing the pathological

121 cterized TFR as CXCR5(+)CCR7(-) "follicular" T regulatory cells in lymphoid tissues of healthy rhesus

122 These results reveal an unexpected role for T regulatory cells in promoting the recruitment of MCps

123 ed infiltration of activated macrophages and T regulatory cells in skin and digit joints as well as b

124 ter constitutive phosphorylation of STAT5 in T regulatory cells in spleen cells compared with mice tr

125 and highlight the key role for TGF-beta1 and T regulatory cells in the establishment and maintenance

126 e selection including elimination of natural T regulatory cells in the thymus.

127 with anti-CD40/CpG + IC/anti-CTLA-4 reduced T regulatory cells in the tumors and was effective again

128 a reduction in the number of CD4(+)FoxP3(+) T regulatory cells in the tumors.

129 ge, SHIV-immunized RM had significantly more T regulatory cells in the vagina than the unimmunized RM

130 IL-10 conversion of CD4 T cells to CD4 FoxP3 T regulatory cells in vitro, and DHA-treated M2 macropha

131 They find that DHA induces FoxP3 T regulatory cells in vivo, M2 macrophages drive transfo

132 eukin 10 and FOXP3, and increased follicular T-regulatory cells in pretreatment mice.

133 cantly reduced the numbers of CD4(+)Foxp3(+) T-regulatory cells in the tissue.

134 nd consequent induction of immunosuppressive T-regulatory cells in tumor tissue promote immune tolera

135 ivers, LSECs are active in the generation of T regulatory cells, in hepatic fibrosis LSECs induce an

136 tivation of CD4 T cells, as well as FOXP3(+) T regulatory cells, in response to YFV vaccination prece

137 CD4(+) T-cell lineages, Th1, Th2, Th17, and T-regulatory cells, in their gene expression profiles.

138 eficit in CD4(+) TCRbeta(+) Foxp3(+) CD25(+) T regulatory cells, increased IL-6 and IL-17 production

139 ose-dependent, cell contact-independent, and T-regulatory cell-independent manner.

140 These data identify the critical role of CD8-T regulatory cell interactions in regulating the suppres

141 thogen recognition receptors in human FOXP3+ T regulatory cells is established, yet the function of t

142 n of pathogen recognition receptors in human T regulatory cells is the protection against death recep

143 hat the balance between T-helper (Th) 17 and T-regulatory cells is an important factor in toxoplasmos

144 ompanied by an increase in the proportion of T regulatory cells; it is speculated that this may compe

145 n response to fetal tissue, and depletion of T regulatory cells led to an increase in fetal-specific

146 ions of solid organ transplantation and that T-regulatory cells may function toward maintenance of th

147 eted T cells acquire intrinsic resistance to T regulatory cell-mediated inhibition.

148 iate ratio of conventional T lymphocytes and T-regulatory cells, natural killer cells, gamma delta T

149 Naturally occurring Foxp3(+)CD4(+)CD25(+) T regulatory cell (nTreg)-mediated suppression of lung a

150 d, genetically targeted and expanded natural T regulatory cells (nTreg).

151 ctivity of CD4(+)CD25(+) naturally occurring T regulatory cells (nTregs) in wild-type (WT) hosts.

152 Naturally occurring CD4(+)CD25(+)Foxp3(+) T regulatory cells (nTregs) regulate lung allergic respo

153 (Th1, Th2, and Th17) and regulatory (natural T regulatory cells [nTregs] and adaptive Treg cells [aTr

154 y elevated TGF-beta1 and high nasopharyngeal T regulatory cell numbers, is crucial for prolonged carr

155 tors and percentage of CD4(+)CD25(+)FoxP3(+) T regulatory cells observed in E2-deficient animals.

156 not associated with differences in levels of T regulatory cells or baseline pro-inflammatory cytokine

157 numbers of IgM+CD21-/low memory B cells and T-regulatory cells (P = .03), and positive correlations

158 teronyssinus-induced CD4(+) CD25(+) FOXP3(+) T regulatory cell percentage, intracellular Foxp3 expres

159 oting FoxP3(+)RoRgammat(+)IL17(+) pathogenic T-regulatory cells (pgTreg), with a concomitant restorat

160 smokers' and nonsmokers' AM induced FoxP3(+) T regulatory cell phenotype responses in allogeneic admi

161 nitial experiment 1 protocol, lamina propria T regulatory cell phenotype was evaluated by Foxp3 expre

162 numbers of CD4(+) T cells of T-helper 2 and T-regulatory cell phenotypes.

163 e into pathogenic Th1 and Th17 or protective T regulatory cells plays a pivotal role in the pathogene

164 a, and tumor development, whereas Smad3(-/-) T-regulatory cells provided no protection.

165 Adoptive transfer of WT CD4(+)CD25(+) T-regulatory cells provided significant protection of Sm

166 included serum creatinine (SCr), peripheral T-regulatory cells (pTregs)(127/CD4+/25), and DSA for gr

167 oral CD8(+) T effector/CD4(+)CD25(+)Foxp3(+) T regulatory cell ratio.

168 rization, along with increased T effector to T regulatory cell ratios.

169 Th17 cytokines and exhibit skewed T effector/T regulatory cell ratios.

170 epatitis infection with TGFbeta activity and T regulatory cell recruitment to establish a favorable m

171 Using reporter mice, we observed that these T regulatory cells released substantial amounts of IL-10

172 contrast to restoration of MDSCs, levels of T regulatory cells remained reduced in BRAFi-resistant t

173 med to investigate the efficacy, safety, and T regulatory cell response of vitamin D as an adjunct to

174 The T regulatory cell response to immune activation increase

175 The percentage of LP T regulatory cells significantly decreased with TPN in W

176 We hypothesized that T-regulatory cells specific for donor alloantigens would

177 d CD4(+) T cell responses and alterations in T regulatory cells (T(reg) cells) play a critical role i

178 metabolize vitamin A and stimulate Foxp3(+) T regulatory cells (T(reg) cells).

179 a chemokine associated with infiltration of T regulatory cells (T(reg)).

180 t interactions with T cells, either inducing T regulatory cells (T(REG)s) or causing anergy.

181 s to support negative selection and Foxp3(+) T-regulatory cell (T-reg) development.

182 poptosis of CD8+ T cells and infiltration of T-regulatory cells (T(reg)).

183 expansion of CD4+ CD25+ Foxp3+ and TGF-beta+ T-regulatory cells (T-regs) after Yersinia infection tha

184 tudies have identified an effector subset of T regulatory cells termed T follicular regulatory (Tfr)

185 in higher levels of class I in CD4(+)CD25(+) T regulatory cells than in conventional CD4(+)CD25(-) T

186 Ag-SP infusion also induces T regulatory cells that are dispensable for tolerance in

187 uding T regulatory type 1 cells, a subset of T regulatory cells that exert their suppressive activity

188 T regulatory cells that express the transcription factor

189 higher expression of 24-hydroxylase than Th2/T regulatory cells, that was reverted by LOV or ROCK inh

190 ilar proportions of CD86(+) DCs and Foxp3(+) T regulatory cells, the SP-A(-/-) mice had elevated prop

191 ors to subvert proinflammatory signaling via T regulatory cells, thereby inducing anti-inflammatory e

192 vel, both mDCs and plasmacytoid DCs generate T regulatory cells through an IDO1/IDO2-dependent mechan

193 city may augment suppression of Th2 cells by T regulatory cells, through mechanisms that involve T ce

194 e product (WASP) serves an essential role in T regulatory cells to contain Th2 effector cell differen

195 newly identified inhibitory cytokine used by T regulatory cells to control T cell-driven immune respo

196 anism that involves IL-10 and CD4(+)FoxP3(+) T regulatory cells to dampen exaggerated mucosal inflamm

197 le of inducing in T lymphocytes, the pivotal T regulatory cell transcription factor forkhead box P3 (

198 stablished a method of CD4(+)CD25(+)FoxP3(+) T regulatory cell (Treg) enrichment from cryopreserved U

199 (TGF-beta) and concomitantly an increase in T regulatory cell (Treg) function.

200 depleting and destabilizing the intratumoral T regulatory cell (Treg) population, the precise mechani

201 art mediated through induction of a FoxP3(+) T regulatory cell (Treg) response.

202 d (CB) fetal T cell differentiation into key T regulatory cell (Treg) subsets.

203 CD4 T cells, including T regulatory cells (Treg cells) and effector T helper ce

204 A proper balance between Th17 and T regulatory cells (Treg cells) is critical for generati

205 e possibility that simultaneous expansion of T regulatory cells (Treg) and T effector cells early pos

206 TGFbeta and IL10 favored generation of T regulatory cells (Treg) and Th2-oriented responses tha

207 T regulatory cells (Treg) avert autoimmunity, but their

208 The overwhelming body of research on T regulatory cells (Treg) has focused on CD4 + CD25 + Fo

209 f Th2 responses in allergic disease, whereas T regulatory cells (Treg) have been shown to suppress pr

210 cells regulated the number of CD4(+)Foxp3(+) T regulatory cells (Treg) in the CNS during EAE.

211 The accumulation of CD4(+) T regulatory cells (Treg) in tumor tissue is a widely de

212 and preferentially induced the expansion of T regulatory cells (Treg) in vitro and in vivo Targeted

213 T regulatory cells (Treg) play an important role in the

214 myeloid-derived suppressor cells (MDSC) and T regulatory cells (Treg) play important roles in immune

215 er, in the clinical setting, CD4(+) CD25(hi) T regulatory cells (Treg) present within the tumor micro

216 hanism involves the accumulation of FOXP3(+) T regulatory cells (Treg), a class of suppressive T cell

217 lockade reduced accumulation of intratumoral T regulatory cells (Treg), but it was insufficient to su

218 Before this therapy was initiated, T regulatory cells (Treg), Th17, and granulocytic myeloi

219 le for it in mediating recruitment of CD4(+) T regulatory cells (Treg).

220 recent advances in the fields of intestinal T-regulatory cell (Treg) and tolerogenic dendritic cell

221 viral adaptive responses and contributing to T-regulatory cell (Treg) development.

222 Anti-CTLA4 predominantly inhibits T-regulatory cells (Treg cells), thereby increasing the

223 T-regulatory cells (Treg) and mast cells (MC) are abunda

224 rease the frequency of CD4(+)CD25(+)FoxP3(+) T-regulatory cells (Treg) relative to conventional T cel

225 cancer requires recruitment and expansion of T-regulatory cells (Treg) that promote escape from host

226 of FoxP3(+)RoRgammat(-)IL17(-) conventional T-regulatory cells (Treg).

227 ively re-adding CD4(+) CD25(bright) T cells (T regulatory cells, Treg), their effect on drug-specific

228 ects on either the donor T effector cells or T regulatory cells Tregs in vitro.

229 effect of vitamin D on lung histology, AHR, T regulatory cells (Tregs) and BALF cytokines was examin

230 minate immunosuppressive populations such as T regulatory cells (Tregs) and myeloid-derived suppresso

231 Thymic-derived natural T regulatory cells (Tregs) are characterized by function

232 T regulatory cells (Tregs) are critical in shaping the l

233 Foxp3(+) T regulatory cells (Tregs) are critically important for

234 ies in animal models suggest that intragraft T regulatory cells (Tregs) are important in maintaining

235 Forkhead box P3(+) T regulatory cells (Tregs) are key players in maintainin

236 Probiotic group coincided with higher ileal T regulatory cells (Tregs) before and after challenge, a

237 FOXP3-expressing T regulatory cells (Tregs) can be divided into two disti

238 warz and Schwarz demonstrate that UV-induced T regulatory cells (Tregs) can influence the biology of

239 were resistant to killing by CD4(+)Foxp3(+) T regulatory cells (Tregs) compared with wild-type DCs.

240 T regulatory cells (Tregs) control immune homeostasis by

241 Intratumoral accumulation of T regulatory cells (Tregs) creates an immunosuppressive

242 Activated T regulatory cells (Tregs) express latent TGF-beta1 on t

243 T regulatory cells (Tregs) have been associated with pro

244 and expands the numbers of immunomodulatory T regulatory cells (Tregs) in animal models.

245 T regulatory cells (Tregs) in the spleen, pancreatic isl

246 Reduced T regulatory cells (Tregs) inversely correlate with arth

247 ever proven in vivo, that the eye can induce T regulatory cells (Tregs) locally.

248 ntering SAg-mediated T cell activation using T regulatory cells (Tregs) might be beneficial in diseas

249 gulatory functions of B10 cells and FoxP3(+) T regulatory cells (Tregs) overlap or influence EAE immu

250 Notably, T regulatory cells (Tregs) showed significantly lower ex

251 Allergic conjunctivitis did affect T regulatory cells (Tregs) that support graft survival.

252 reased numbers and proliferation of FoxP3(+) T regulatory cells (Tregs), a model T cell population kn

253 iation factor for immunosuppressive Foxp3(+) T regulatory cells (Tregs), an increase in Foxp3(+) Treg

254 nsplantation, we reported that donor-derived T regulatory cells (Tregs), coinfused with conventional

255 Foxp3(+) T regulatory cells (Tregs), conventional CD4(+)Foxp3(-)

256 We evaluated T regulatory cells (Tregs), myeloid-derived suppressor c

257 use prevents autoimmune attack by recruiting T regulatory cells (Tregs), protecting mice from diabete

258 ically address the effects of type I IFNs on T regulatory cells (Tregs), we studied mixed bone marrow

259 d whether their function is coordinated with T regulatory cells (Tregs).

260 mouse by promoting the local recruitment of T regulatory cells (Tregs).

261 crophages were unable to sufficiently induce T regulatory cells (Tregs).

262 ts and limited efficacy due to activation of T regulatory cells (Tregs).

263 ciency of tolerance-inducing CD4+CD25+FoxP3+ T regulatory cells (Tregs).

264 , IL-12p70, IL-10, TGF-beta, and IL-17), and T regulatory cells (Tregs).

265 tuberculosis-expanded CD4(+)CD25(+)FOXP3(+) T regulatory cells (Tregs).

266 numbers and function of CD4+CD25(high)FOXP3+ T regulatory cells (Tregs).

267 cells (Tfhs), and forkhead box P3 (Foxp3)(+) T regulatory cells (Tregs).

268 g inducing anti-inflammatory IL-10-secreting T regulatory cells (Tregs).

269 yzed early events and selective depletion of T regulatory cells (Tregs).

270 r T cells and opposing inhibitory effects on T regulatory cells (Tregs).

271 CD4(+)CD25(+)Foxp3(+) T-regulatory cells (Tregs) accumulate in tumors; however

272 nfection by bystander immune cells including T-regulatory cells (Tregs) and natural killer (NK) cells

273 T-regulatory cells (Tregs) are found infiltrating tumors

274 Foxp3(+) T-regulatory cells (Tregs) are key to immune homeostasis

275 Foxp3(+) T-regulatory cells (Tregs) are primarily generated in th

276 BACKGROUND & AIMS: Foxp3(+) T-regulatory cells (Tregs) maintain intestinal homeostas

277 T-regulatory cells (Tregs), a subset of CD4+ T cells, ha

278 tress, regulating survival in murine natural T-regulatory cells (Tregs), an immune subset controlling

279 important in CD4 T-effector and/or Foxp3(+) T-regulatory cells (Tregs), and we found that B10.S-Eae5

280 /gal-9 was inhibited in the absence of donor T-regulatory cells (Tregs), GVHD was inhibited.

281 Although CD4(+)CD25(+) T cells (T regulatory cells [Tregs]) and natural killer T cells (

282 nders had increased IL-10-producing FOXP3(+) T regulatory cells upon vaccination, only in hepatitis B

283 (+) T cells, the differentiation of Foxp3(+) T regulatory cells was suppressed, whereas Th17 cells we

284 lightly prevalent over Th2, whereas Th17 and T regulatory cells were <1%.

285 higher frequencies of the immunosuppressive T regulatory cells were also detected in the virus-infec

286 Frequencies of Foxp3 T regulatory cells were comparable in both surviving and

287 The levels of T regulatory cells were measured using flow cytometry at

288 T regulatory cells were nearly abolished and antitumor i

289 c CD3(+) alphabeta TCR(+) cells and Foxp3(+) T regulatory cells were present in DKO mice but signific

290 T regulatory cells were significantly decreased in AA pa

291 hocytes in the draining lymph nodes, whereas T-regulatory cells were dampened.

292 In mixed chimeras, increased numbers of T-regulatory cells were found in draining compared with

293 Elevated levels of CD3+ FoxP3+ T-regulatory cells were found in skin and muscle of vasc

294 n and muscle, elevated levels of CD3+ FoxP3+ T-regulatory cells were found in the skin and muscle obt

295 ced vascular oxidative stress while FoxP3(+) T-regulatory cells were unaltered.

296 hanges, together with reduced recruitment of T regulatory cells, were associated with higher ratios o

297 MPL monotherapy was restored by depletion of T regulatory cells, whereas eliminating CD8(+) T cells a

298 +) T cells rather than CD4(+)CD25(+)Foxp3(+) T regulatory cells, which were also induced by imiquimod

299 rickettsiosis are Th1-cell-related adaptive T-regulatory cells, which substantially contribute to su

300 pathology, 9142-primed mice also had splenic T regulatory cells with greater suppressive activity tha