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1 TGN concentrations of >220 pmol/8 x 10(8) RBCs are assoc
3 ed 6-MMP (6-methyl mercaptopurine) and low 6-TGN (6-thioguanine nucleotide) consistent with AZA-induc
4 GN and post-TGN cargo without the need for a TGN marker that universally cosegregates with all cargo.
5 P4a) and YIP4b (formerly YIP2), which form a TGN-localized complex with ECHIDNA (ECH) in Arabidopsis
10 plex mediate the transport of MIG-14/Wls and TGN-38/TGN38 cargo proteins from the recycling endosome
13 Furthermore, we find that retrograde cargo TGN-38 is trapped in early endosomes after depletion of
14 s, there was no association between red cell TGN levels and taking 6-MP with food versus without (206
20 s to early endosomes/trans-Golgi network (EE/TGN) and is constitutively endocytosed through a monoubi
22 ther the trans-Golgi network/early endosome (TGN/EE)-localized vacuolar H(+)-ATPase activity nor the
25 the trans-Golgi network and early endosomes (TGN/EE) function as the central junction for major endom
30 es the requirement of K33-ubiquitination for TGN-pool F-actin assembly and post-Golgi trafficking.
32 tion, silencing retromer or disrupting Golgi/TGN organization all impair efficient TSH-dependent cAMP
34 inhibiting PKA II/interfering with its Golgi/TGN localization, silencing retromer or disrupting Golgi
36 c reticulum and, after passage through Golgi/TGN to the cell division plane, transformed into fusogen
37 findings support the notion that HCV hijacks TGN-endosome trafficking to facilitate particle assembly
38 disruption of Crn7-Eps15 interaction impairs TGN-pool F-actin assembly, a process essential for gener
42 hat the ECH/YIP4 complex plays a key role in TGN-mediated secretion of pectin and hemicellulose to th
43 herers, high intra-individual variability in TGN levels contributed to increased relapse risk (hazard
45 gest that the virus perturbs a specific late TGN secretory pathway resulting in buildup of a key prot
46 se appear to be a subdomain of the mammalian TGN, showing only partial overlap with the TGN marker go
48 al compartments and the trans-Golgi network (TGN) [including the retromer complex (Vps35, Vps26) and
49 ansport of BACE1 to the trans-Golgi network (TGN) and a delayed delivery of BACE1 to the lysosomes, t
50 fic retrogradely to the trans-Golgi network (TGN) and activate endogenous Gs-proteins in the retromer
52 n transport between the trans-Golgi network (TGN) and early endosome (EE) requires Drs2, a phospholip
57 ed cupro-enzymes in the trans-Golgi network (TGN) and exports excess copper out of cells by trafficki
58 L20 is localized to the trans-Golgi network (TGN) and is important for post-Golgi trafficking by prom
59 t CLN3 localizes to the trans-Golgi network (TGN) and partitions with buoyant microdomain fractions.
60 rade trafficking to the trans-Golgi network (TGN) and reaches a steady-state distribution in the TGN
61 FR/RTK anchoring on the trans-Golgi network (TGN) and recycling back to the plasma membrane, leading
62 ves sequentially to the trans-Golgi network (TGN) and recycling endosomes before nuclear translocatio
65 trafficking toward the trans-Golgi network (TGN) and the Golgi apparatus correlates with transductio
66 7B was localized to the trans-Golgi network (TGN) and the plasma membrane of the soma and dendrites b
67 ins transit through the trans-Golgi network (TGN) and the prevacuolar compartment (PVC) en route to t
70 rade transport from the trans-Golgi network (TGN) by facilitating localized actin assembly at the TGN
71 f SM homeostasis at the trans-Golgi network (TGN) by treatment of HeLa cells with d-ceramide-C6, whic
72 ciated with a subapical trans-Golgi network (TGN) compartment, whose cytoplasmic position at the poll
73 sicles that emerge from trans-Golgi network (TGN) compartments and regulates polarized membrane traff
75 of ARF1 and BIG4 at the trans-Golgi network (TGN) depends on ECHIDNA (ECH), a plant homolog of yeast
77 me and L2 travel to the trans-Golgi network (TGN) following exit from the LE, while L1 is retained.
81 V16 pseudogenome in the trans-Golgi network (TGN) in Pyk2-depleted cells, suggesting that the kinase
82 early endosomes and the trans-Golgi network (TGN) in unstimulated human colonic epithelial cells.
83 post-Golgi compartment trans-Golgi Network (TGN) is a central hub divided into multiple subdomains h
84 c vesicles at the yeast trans-Golgi network (TGN) is believed to be mediated by their coalescence wit
86 ncipal functions of the trans Golgi network (TGN) is the sorting of proteins into distinct vesicular
88 enance of the Golgi and trans Golgi network (TGN) PI4P pools, however, the actual targeting mechanism
90 lated checkpoint at the trans-Golgi network (TGN) that controls the surface delivery of the delta opi
92 s from endosomes to the trans-Golgi network (TGN) to prevent proteolytic processing or by directing n
93 se III (Chs3p) from the trans-Golgi network (TGN) to the cell surface and to and from the early endos
94 is transported from the trans-Golgi network (TGN) to the cell surface in specific carriers called CAR
95 beta1 integrin from the trans-Golgi network (TGN) to the EC surface, thus allowing FN fibrillogenesis
97 for transport from the trans-Golgi network (TGN) to the late endosome/prevacuolar compartment (PVC)
98 ber of cargoes from the trans-Golgi network (TGN) to the plasma membrane in Saccharomyces cerevisiae
99 mbrane protein from the trans-Golgi network (TGN) to the plasma membrane in the root epidermis of Ara
101 exit of GPP130 from the trans-Golgi network (TGN) toward lysosomes is mediated by the sorting recepto
102 e-dependent endosome-to-trans-Golgi network (TGN) transport of the cation-independent mannose 6-phosp
103 or several decades, the trans-Golgi network (TGN) was considered the most distal stop and hence the u
104 its trafficking to the trans-Golgi network (TGN) were unaffected, indicating that the decreased intr
107 at ANK localizes to the trans-Golgi network (TGN), clathrin-coated vesicles and the plasma membrane.
108 localized in the Golgi/trans-Golgi network (TGN), in the early endosomes, and on the plasma membrane
109 ) from endosomes to the trans-Golgi network (TGN), is thought to consist of a cargo-selective VPS26-V
111 ein is localized to the trans-Golgi network (TGN), prevacuolar compartment (PVC), and plasma membrane
112 and associated with the trans-Golgi network (TGN), suggesting that FgVps35 functions at the donor end
113 of the receptor in the trans-Golgi network (TGN), to the effect that overexpressed PIST reduces acti
115 step takes place at the trans-Golgi network (TGN), where Rod1 localizes dynamically upon triggering e
117 id is trafficked to the trans-Golgi network (TGN), whereupon it enters the nucleus during mitosis.
118 ining vesicles from the trans-Golgi network (TGN), which is regulated by a domain of protein RS1 (RSC
119 show a critical role of trans-Golgi network (TGN)-endosome trafficking during the assembly, but princ
121 ein is required for the trans-Golgi network (TGN)-mediated trafficking of the auxin influx carrier AU
132 LB1 associated with the trans-Golgi network (TGN)/early endosome (EE) and tracked along filamentous a
134 adherence, red cell thioguanine nucleotide (TGN) levels, and risk of relapse in children with TMPT w
136 sured as erythrocyte thioguanine nucleotide [TGN] levels) in children with acute lymphoblastic leukem
138 acyl-chain length links lipid composition of TGN subdomains with polar secretory trafficking of PIN2
140 l microsomal spread and 2) identification of TGN and post-TGN cargo without the need for a TGN marker
142 ing clathrin-coated vesicles, caused loss of TGN localization and somatodendritic polarity of ATP7B.
144 ant cell division in which a large number of TGN-derived membrane vesicles fuse with one another to f
145 argo selectivity for betagamma regulation of TGN to PM transport and a novel role for betagamma in me
146 nterfering RNA (siRNA)-mediated silencing of TGN-associated adaptor proteins and a panel of dominant
147 found that Eqt-SM is enriched in a subset of TGN-derived secretory vesicles that are also enriched in
148 y, we found that ATL1 interacts with EDR1 on TGN/EE vesicles and that EDR1 suppresses ATL1-mediated c
150 tudies showed that cleavage occurs in a post-TGN compartment and that lysosomotropic agents enhance s
151 spread and 2) identification of TGN and post-TGN cargo without the need for a TGN marker that univers
153 eir arrival at the cell surface and the post-TGN breakup of large pleomorphic membrane fragments that
156 S2 perturbs TGN architecture, redistributing TGN membranes to closely associate with HCV core protein
157 endosomal compartments, decreased retrograde TGN trafficking, and increased Abeta production in H4 ne
158 a reaction that requires Ca(2+), the soluble TGN-resident protein Cab45 is necessary for the sorting
165 colocalizes with secretory proteins and the TGN Ca(2+) pump (SPCA1) in specific TGN microdomains.
169 irs by their degree of colocalization at the TGN and by the evolution of colocalization during their
171 of a novel functional protein complex at the TGN and its key members: cytosolic PKD2 binds ARF-like G
172 demonstrate the sorting of native SM at the TGN and its transport to the plasma membrane by specific
173 not sialylated by a sialyltransferase at the TGN and that this enzyme and its substrate TGN46 could n
176 tion of AP-1- and GGA-coated carriers at the TGN but may be dispensable for outward traffic en route
177 localization of YIP4 and ECH proteins at the TGN is interdependent and influences the localization of
178 to membranes, whereas GBF1 localized at the TGN mediates ARF activation that leads to the recruitmen
180 that generation of putrescine by ODC1 at the TGN stimulates release of SGLT1-containing vesicles.
181 ormation of this multiprotein complex at the TGN that controls constitutive secretion of matrix metal
182 facilitating localized actin assembly at the TGN through K33-linked ubiquitination of coronin 7.
183 mes and lysosomes is thought to occur at the TGN through recognition of sorting signals in the cytoso
184 we show that sphingomyelin production at the TGN triggers a signalling pathway leading to PtdIns(4)P
185 eractions of p14 with activated Rab11 at the TGN, resulting in p14 sorting into AP1-coated vesicles f
187 binds to different receptor proteins at the TGN, which trigger release of vesicles with different tr
197 R1 negatively regulates ATL1 activity at the TGN/EE and thus controls stress responses initiated by A
198 rf-binding protein)-coated structures at the TGN/endosomal interface, resulting in the peripheral dis
200 DISLL, which controls transport between the TGN and endosomes via interaction with GGA proteins.
202 e found that TGN46, which cycles between the TGN and the plasma membrane, was not sialylated by a sia
203 thrin/AP-mediated cycling of ANK between the TGN, endosomes, and the cell surface regulates membrane
207 ar sites and reveals a critical role for the TGN in GPCR signaling.Recent investigations suggest that
208 e incoming viral genome dissociates from the TGN and associates with microtubules after the onset of
209 d auxin carriers to plasma membrane from the TGN and reveal how trafficking of auxin influx carriers
210 een implicated in polar trafficking from the TGN but the underlying mechanisms linking lipid composit
211 flux carrier to the plasma membrane from the TGN during hook development and defects in BIG or ARF1 r
212 that timely exit of these proteins from the TGN is critical for effective pre-invasive immune respon
218 that CTL1 regulates protein sorting from the TGN to the PM through its function in lipid homeostasis.
223 PV-harboring transport vesicles bud from the TGN, followed by association with mitotic chromosomes.
224 mation of tubular membrane carriers from the TGN, perinuclear accumulation of early endosomes and imp
225 generic ACT7-dependent trafficking from the TGN, the EXOCYST84b (EXO84b) tethering factor mediates P
226 ain contacts initiate exit of ATP7B from the TGN, whereas increased phosphorylation may be needed to
232 eptors can be released from retention in the TGN by coexpression of the plasma membrane-associated sc
234 e studies demonstrate that clustering in the TGN is required for normal biosynthetic apical sorting o
237 at levels of both GM1 and cholesterol in the TGN-endosomal compartment are upregulated in some inheri
241 hermore, HPV16 capsid proteins arrive in the TGN/Golgi in a retromer-dependent fashion during entry,
242 d to efficiently traffic retrograde into the TGN and endoplasmic reticulum and into the recycling end
246 iched in secretory vesicle subdomains of the TGN and are critical for de novo polar secretory sorting
247 accompanied by apparent fragmentation of the TGN and redistribution of K15P to a dispersed peripheral
249 icellulose and distinguishes the role of the TGN in secretion from its roles in endocytic and vacuola
253 x with actin to modulate the function of the TGN/EE at the intersection of the exocytic and endocytic
255 LISA and coimmunoprecipitation show that the TGN/endosomal small GTPase Rab14 and PKCiota interact di
256 ense proteins continuously cycle through the TGN and that timely exit of these proteins from the TGN
259 The syntaxin TlgB(Tlg2) localizing to the TGN appears to mediate retrograde traffic connecting pos
260 Transport from recycling endosomes to the TGN has also been reported, but much less is understood
263 s suggest that retrograde trafficking to the TGN induces local Gs-protein activation and cAMP/PKA sig
265 and UL37 are known to be transported to the TGN sites of virus envelopment and to function in virion
266 constitutive internalization of LGR5 to the TGN suggests the existence of novel biochemical roles fo
267 of internalized Shiga toxin B subunit to the TGN, as well as recycling of internalized transferrin to
268 raction mediates localization of Sec7 to the TGN, because deletion of the HDS1 domain or mutation of
269 adation in lysosomes and retrieves it to the TGN, where insulin--responsive vesicles are formed.
281 e early or late endosome and traffics to the TGN/Golgi via the retrograde pathway during cell entry.
289 UB13 fusion protein (YFP-PUB13) localizes to TGN and Golgi compartments and that PUB13, PI4Kbeta1, an
290 (Crn7), which facilitates Crn7 targeting to TGN through a ubiquitin-dependent interaction with Eps15
292 620N) there is a perturbation in endosome-to-TGN transport but not endosome-to-plasma membrane recycl
293 nal effects on retromer-mediated endosome-to-TGN transport, provide new insight into retromer deregul
298 lasma membrane only in border cells, whereas TGN-LVs containing the XG and PGA/RG-I epitopes fuse wit
299 They also colocalize to similar extents with TGN and recycling endosome markers, as well as with baso
300 xhibited Ca(2+)-stimulated interactions with TGN SNAREs, and underwent Ca(2+)-stimulated TGN recruitm
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