ライフサイエンスコーパス: TNF-alpha converting enzyme

1 allow cleavage by the metalloprotease TACE (TNF-alpha-converting enzyme).

2 ncreases the activity of the metalloprotease TNF-alpha-converting enzyme.

3 ed shedding, but shedding was independent of TNF-alpha-converting enzyme (a disintegrin and metallopr

4 tivation of the metalloprotease TACE/ADAM17 (TNF-alpha-converting enzyme), a previously unknown p53 t

5 This enhanced TNF-alpha-converting enzyme activity significantly incre

6 The latter enzymes, as well as TNF alpha-converting enzyme and FasL-converting enzyme,

7 n CMV due to an enhanced activity of ADAM17 (TNF-alpha converting enzyme) and matrix metalloprotease

8 phil elastase, tumor necrosis factor [TNF]), TNF-alpha-converting enzyme, and matrix metalloproteinas

9 pparent deficiency in the level of the major TNF-alpha converting enzyme in adipose tissue to account

10 This enzyme (called the TNF-alpha-converting enzyme, or TACE) is a new member of

11 ages in a manner requiring activation of the TNF-alpha-converting enzyme TACE.

12 TNF alpha converting enzyme (TACE) processes precursor T

13 The tumor necrosis factor (TNF)-alpha converting enzyme (TACE/ADAM-17) is a transme

14 Here, we report that TNF-alpha converting enzyme (TACE) (a disintegrin and me

15 Using the TNF-alpha converting enzyme (TACE) inhibitor, TAPI-1, TP

16 pyl dicarboxylate were examined as potential TNF-alpha converting enzyme (TACE) inhibitors.

17 TNF-alpha converting enzyme (TACE) is a membrane-bound m

18 TNF-alpha converting enzyme (TACE) is a multidomain, mem

19 TNF-alpha converting enzyme (TACE) is the protease respo

20 TNF-alpha converting enzyme (TACE) or disintegrin and me

21 Endothelial deletion of the TNF-alpha converting enzyme (TACE) prevented the TNF-alp

22 sTNF is generated by TNF-alpha converting enzyme (TACE) proteolytic release o

23 TNF-alpha have centered on the inhibition of TNF-alpha converting enzyme (TACE) through the use of hy

24 ane protein that is enzymatically cleaved by TNF-alpha converting enzyme (TACE) to generate a 17-kDa

25 ct with epithelial cells, and by 1 h induced TNF-alpha converting enzyme (TACE) transcription.

26 The TNF-alpha converting enzyme (TACE), a disintegrin and me

27 In the present study, we demonstrate that TNF-alpha converting enzyme (TACE), a disintegrin and me

28 esothelin sheddase activity is mediated by a TNF-alpha converting enzyme (TACE), a member of the matr

29 ly in fibroblasts and monocytes deficient in TNF-alpha converting enzyme (TACE), a sheddase involved

30 F-related apoptosis-inducing ligand (TRAIL), TNF-alpha converting enzyme (TACE), TRAIL receptor (TRAI

31 (solTNF) molecule after being cleaved by the TNF-alpha converting enzyme (TACE).

32 yzed for expression of AR and its activator, TNF-alpha converting enzyme (TACE).

33 The TNF-alpha converting enzyme (TACE; a disintegrin and met

34 TNF-alpha converting enzyme (TACE; ADAM17), a member of

35 Tumor necrosis factor alpha (TNF-alpha) converting enzyme (TACE) is the first discove

36 ase (MAPK) and tumour necrosis factor-alpha (TNF-alpha) converting enzyme (TACE) were also assessed.

37 llagenase-1) or tumor necrosis factor-alpha (TNF-alpha) converting enzyme (TACE).

38 hown to involve tumor necrosis factor alpha (TNF-alpha) converting enzyme (TACE).

39 Tumor necrosis factor alpha (TNF-alpha)-converting enzyme (TACE) is at the center of

40 uction, which corresponded to an increase in TNF-alpha-converting enzyme (TACE) activity.

41 TNF-alpha-converting enzyme (TACE) cleaves pro-TGF-alpha

42 Shedding mediated by TNF-alpha-converting enzyme (TACE) results in an unattac

43 Metalloprotease inhibitors and TNF-alpha-converting enzyme (TACE) small interfering RNA

44 rophages, by suppressing the activity of the TNF-alpha-converting enzyme (TACE), arguing that MUC1 is

45 lecular mass 26K which can be processed by a TNF-alpha-converting enzyme (TACE), to generate secreted

46 thelial (NCI-H292) cells via metalloprotease TNF-alpha-converting enzyme (TACE)-dependent EGFR activa

47 mucus, and its expression is modulated by a TNF-alpha-converting enzyme (TACE)-EGF receptor pathway

48 ionally by inhibiting cellular processing by TNF-alpha-converting enzyme (TACE).

49 TNF-alpha-converting enzyme (TACE, herein denoted as Ada

50 Targeting this protease, TNF-alpha-converting enzyme (TACE; also referred to as a

51 ADAM 17 (TNF-alpha converting enzyme, TACE) is a potential target

52 vation of the tmTNF cleavage metalloprotease TNF-alpha-converting enzyme via p38 MAP kinase activatio