ライフサイエンスコーパス: TNF-related apoptosis-inducing ligand

1 ate cells sensitizes to cell death by TRAIL (TNF-related apoptosis-inducing ligand).

2 nd TNF superfamily proteins 2, 7, 9, and 10 (TNF-related apoptosis-inducing ligand).

3 uced by tumor necrosis factor (TNF) alpha or TNF-related apoptosis-inducing ligand.

4 nse to death receptor ligands, TNF-alpha and TNF-related apoptosis-inducing ligand.

5 tumor necrosis factor receptor 1 (2.29), and TNF-related apoptosis-inducing ligand (0.34).

6 also called TRAIL for tumor necrosis factor (TNF)-related apoptosis-inducing ligand [2]) belongs to t

7 Apo-2 ligand (Apo-2L)/TNF-related apoptosis-inducing ligand, a new member of t

8 , accompanied with upregulated expression of TNF-related apoptosis-inducing ligand and activation of

9 Also, PS-341 enhanced TRAIL (TNF-related apoptosis-inducing ligand) and TNFalpha (tum

10 other contexts, interactions between TRAIL (TNF-related apoptosis-inducing ligand/Apo-2L) and its re

11 of human recombinant tumor necrosis factor (TNF)-related apoptosis-inducing ligand/Apo2 ligand (TRAI

12 so bind to other TNF family members, such as TNF-related apoptosis-inducing ligand/Apo2 ligand (TRAIL

13 Apoptosis ligand 2 tumor necrosis factor (TNF)-related apoptosis-inducing ligand (Apo2L/TRAIL) bel

14 Apo2 ligand/tumor necrosis factor (TNF)-related apoptosis-inducing ligand (Apo2L/TRAIL) mai

15 We have previously shown that Apo2 ligand/TNF-Related apoptosis inducing ligand (Apo2L/TRAIL) indu

16 ein comprising the ectodomain of Apo2 ligand/TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) has

17 E-selectin adhesion protein and Apo2L/TRAIL (TNF-related apoptosis-inducing ligand) apoptosis ligand

18 n of p38alpha signaling and up-regulation of TNF-related apoptosis-inducing ligand are detected in ap

19 up-regulation of Fas, death receptor 3, and TNF-related apoptosis-inducing ligand by CD30 indicates

20 ion, we show that murine IFN-gamma and human TNF-related apoptosis-inducing ligand can be displayed o

21 ls to apoptosis induced by TNF-family member TNF-related apoptosis-inducing ligand, consistent with a

22 MYC, up-regulation of surface levels of the TNF-related apoptosis-inducing ligand death receptor 5,

23 ta) as a gene whose inactivation potentiates TNF-related apoptosis-inducing ligand death receptor-med

24 TRAIL (TNF-related apoptosis-inducing ligand) death receptors D

25 ytosis and apoptotic signaling downstream of TNF-related apoptosis-inducing ligand-death receptor (TR

26 The mAb 4H6 (IgG1) competed with Apo2L/TNF-related apoptosis-inducing ligand (DR4's ligand) for

27 tory markers tumor necrosis factor (TNF) and TNF-related apoptosis-inducing ligand in irradiated skin

28 osis induced by the cell death ligand TRAIL (TNF-related apoptosis-inducing ligand) in human cancer c

29 arabine (Ara-C), etoposide, or Apo-2L/TRAIL (TNF-related apoptosis-inducing ligand)-induced apoptosis

30 crosis factor-induced apoptosis but not from TNF-related apoptosis-inducing ligand-induced apoptosis.

31 l death, with no effect seen on TNF-alpha or TNF-related apoptosis-inducing ligand-induced apoptosis.

32 TRAIL (TNF-related apoptosis-inducing ligand) induces apoptosis

33 mbination with TRAIL (tumor necrosis factor [TNF]-related apoptosis-inducing ligand) induces a synerg

34 TRAIL, the TNF-related apoptosis-inducing ligand, induces apoptosis

35 , tumor necrosis factor alpha (TNFalpha) and TNF-related apoptosis-inducing ligand inhibit overall tr

36 Furthermore, the cytokines Fas ligand, TNF-related apoptosis-inducing ligand, interleukin (IL)-

37 TRAIL (TNF-related apoptosis-inducing ligand) is a member of th

38 TRAIL (TNF-related apoptosis-inducing ligand) is a potential an

39 TRAIL (tumor necrosis factor [TNF]-related apoptosis-inducing ligand) is a molecule th

40 TNF-alpha (Tumor Necrosis Factor) or TRAIL (TNF-Related Apoptosis-Inducing Ligand); is an extremely

41 s mediated by TRAIL (tumour necrosis factor (TNF)-related apoptosis-inducing ligand) it is common for

42 substantial increase in TNF-alpha and TRAIL (TNF-related apoptosis-inducing ligand)-mediated apoptosi

43 Fs) resulted in resistance to TNF-alpha- and TNF-related apoptosis-inducing ligand-mediated apoptosis

44 T-cells; TNF, tumor necrosis factor; TRAIL, TNF-related apoptosis-inducing ligand; OPG, osteoprotege

45 gonist rituximab in combination with rhApo2L/TNF-related apoptosis inducing ligand or fenretinide, a

46 pression/secretion and function of NKp30 and TNF-related apoptosis-inducing ligand, particularly amon

47 ors: tumor necrosis factor receptor (TNF-R), TNF-related apoptosis-inducing ligand receptor (TRAIL-R)

48 Herein we show that TNF-related apoptosis-inducing ligand receptor (TRAIL-R)

49 d in NS1-immunized rabbits crossreacted with TNF-related apoptosis-inducing ligand receptor 1 (death

50 ic Fas-associated protein with death domain, TNF-related apoptosis-inducing ligand receptor, or Fas s

51 Affected receptors include Fas, TRAIL (TNF-related apoptosis-inducing ligand) receptor 1 (TR1),

52 ew member of this family, TRICK2, the TRAIL (TNF-related apoptosis-inducing ligand) receptor inducer

53 r necrosis factor (TNF)-alpha receptor 1, or TNF-related apoptosis-inducing ligand receptors (DR4 and

54 eceptor (TNFR) superfamily, including TNFR1, TNF-related apoptosis-inducing ligand receptors (TRAIL-R

55 we evaluated two drug formulations of TRAIL (TNF-related apoptosis inducing ligand): soluble and anch

56 soluble extracellular domain of proapoptotic TNF-related apoptosis-inducing ligand (sTRAIL) would mar

57 anzyme degranulation pathway and the TNF/Fas/TNF-related apoptosis-inducing ligand superfamily of apo

58 ng adenovirus E1A and tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) in a repl

59 udies, treatment with tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL, also know

60 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) (Apo2 lig

61 Ligation of DR5 by tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) activates

62 f combining CD437 and tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and Fas l

63 apoptosis induced by tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and one o

64 that plasma levels of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) are eleva

65 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces a

66 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces a

67 late with PML NBs and tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induction

68 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a cyto

69 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a memb

70 Tumor necrosis (TNF)-related apoptosis-inducing ligand (TRAIL) is a memb

71 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a memb

72 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a memb

73 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a memb

74 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a TNF

75 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is an imm

76 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is known

77 Coadministration of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) or TNF-al

78 apoptosis induced by tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) or TNFalp

79 that miR-494 induced Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) resistanc

80 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selective

81 Because tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selective

82 s DR5, a receptor for tumor-necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) that is e

83 diators and products--tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), Fas liga

84 aurosporine (STS) and tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), respecti

85 ic pathways driven by tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), thereby

86 sms in genes encoding tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), TNF- alp

87 in and inhibits tumor necrosis factor-alpha (TNF)-related apoptosis-inducing ligand (TRAIL)-induced a

88 tion of PDC-dependent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated

89 h2-related cytokines, tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-R2/DR5, a

90 osis-inducing protein tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL).

91 death is mediated by tumour-necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL).

92 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)/APO-2L is

93 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)/Apo2 liga

94 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL, APO-2L) i

95 ted increased urinary tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL/Apo-2L) le

96 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL/Apo2L) is

97 nfected with HIV, HIV infection up-regulates TNF-related apoptosis inducing ligand (TRAIL) and death-

98 kappaB ligand (RANKL), TNF-alpha, CD95L, and TNF-related apoptosis inducing ligand (TRAIL) in T cell

99 ng leukocytes to present the cancer-specific TNF-related apoptosis inducing ligand (TRAIL) on their s

100 nce had significantly higher serum levels of TNF-related apoptosis inducing ligand (TRAIL), compared

101 iologically relevant death ligands including TNF-related apoptosis inducing ligand (TRAIL).

102 e T cells used the cognate proteins FasL and TNF-related apoptosis-inducing ligand (TRAIL) (but not T

103 The cytokine TNF-related apoptosis-inducing ligand (TRAIL) and its ce

104 Since the discovery of TNF-related apoptosis-inducing ligand (TRAIL) and its ne

105 past year, knowledge of the system involving TNF-related apoptosis-inducing ligand (TRAIL) and its re

106 gnificantly increases the expression of both TNF-related apoptosis-inducing ligand (TRAIL) and of the

107 mic compound (Smac-mimic), which potentiates TNF-related apoptosis-inducing ligand (TRAIL) and tumor

108 is upregulated in response to treatment with TNF-related apoptosis-inducing ligand (TRAIL) and tumor

109 uclear factor-kappaB (RANK)/RANK ligand, and TNF-related apoptosis-inducing ligand (TRAIL) Apo-2L/TRA

110 s factor (TNF) family of cytokines, FasL and TNF-related apoptosis-inducing ligand (TRAIL) are known

111 tumor necrosis factor-alpha (TNF-alpha) and TNF-related apoptosis-inducing ligand (TRAIL) are produc

112 the thiazolidinedione troglitazone (TZD) and TNF-related apoptosis-inducing ligand (TRAIL) can induce

113 TNF-related apoptosis-inducing ligand (TRAIL) can select

114 t the induction of the proapoptotic molecule TNF-related apoptosis-inducing ligand (TRAIL) during rea

115 fter HIV-1 exposure, which in turn regulates TNF-related apoptosis-inducing ligand (TRAIL) expression

116 Additionally, physapubescin synergizes with TNF-related apoptosis-inducing ligand (TRAIL) for marked

117 TNF-related apoptosis-inducing ligand (TRAIL) has been s

118 The TNF-related apoptosis-inducing ligand (TRAIL) has well-d

119 TNF-related apoptosis-inducing ligand (TRAIL) holds prom

120 the main intrahepatic lymphocytes expressing TNF-related apoptosis-inducing ligand (TRAIL) in CHB.

121 ed apoptosis partly through the induction of TNF-related apoptosis-inducing ligand (TRAIL) in pancrea

122 mined the role of the TNF superfamily member TNF-related apoptosis-inducing ligand (TRAIL) in S. pneu

123 describe an improved approach to delivering TNF-related apoptosis-inducing ligand (TRAIL) in vivo in

124 The TNF-related apoptosis-inducing ligand (TRAIL) induces ap

125 TNF-related apoptosis-inducing ligand (TRAIL) is a death

126 TNF-related apoptosis-inducing ligand (TRAIL) is a membe

127 TNF-related apoptosis-inducing ligand (TRAIL) is a more

128 TNF-related apoptosis-inducing ligand (TRAIL) is a poten

129 TNF-related apoptosis-inducing ligand (TRAIL) is a poten

130 TNF-related apoptosis-inducing ligand (TRAIL) is able to

131 previously shown that endogenously expressed TNF-related apoptosis-inducing ligand (TRAIL) is require

132 Because TNF-related apoptosis-inducing ligand (TRAIL) kills cell

133 Enhanced expression of TNFSF10 or TNF-related apoptosis-inducing ligand (TRAIL) mRNA in un

134 ministration of dTAT NP-encapsulated AT2R or TNF-related apoptosis-inducing ligand (TRAIL) pDNA marke

135 nd (RANKL), TNF-alpha, Fas ligand (FasL) and TNF-related apoptosis-inducing ligand (TRAIL) play pivot

136 TNF-related apoptosis-inducing ligand (TRAIL) promotes i

137 g agents, i.e. monoclonal antibodies against TNF-related apoptosis-inducing ligand (TRAIL) receptor 1

138 family of receptors such as Fas/CD95 and the TNF-related apoptosis-inducing ligand (TRAIL) receptors

139 t the extracellular domain of the four known TNF-related apoptosis-inducing ligand (TRAIL) receptors

140 ur necrosis factor receptor 1 (TNFR1), CD95, TNF-related apoptosis-inducing ligand (TRAIL) receptors,

141 (with high affinity) to the death domain of TNF-related apoptosis-inducing ligand (TRAIL) receptors,

142 he TNFR superfamily, such as Fas, TNFR1, and TNF-related apoptosis-inducing ligand (TRAIL) receptors.

143 ribed to enhance cell survival and to induce TNF-related apoptosis-inducing ligand (TRAIL) resistance

144 TNF-related apoptosis-inducing ligand (TRAIL) selectivel

145 TNF-related apoptosis-inducing ligand (TRAIL) shows prom

146 sduce apoptotic signals upon binding soluble TNF-related apoptosis-inducing ligand (TRAIL) that, like

147 h tumor necrosis factor alpha (TNFalpha) and TNF-related apoptosis-inducing ligand (TRAIL) to potentl

148 TNF-related apoptosis-inducing ligand (TRAIL) was initia

149 Recent evidence suggests that TNF-related apoptosis-inducing ligand (TRAIL), a death-i

150 TNF-related apoptosis-inducing ligand (TRAIL), a member

151 The observation that TNF-related apoptosis-inducing ligand (TRAIL), a member

152 21(WAF1) or death receptor 5 (KILLER/DR5) of TNF-related apoptosis-inducing ligand (TRAIL), and induc

153 L2, tumor necrosis factor alpha (TNF-alpha), TNF-related apoptosis-inducing ligand (TRAIL), and inter

154 ligand (L), CD27L, CD30L, OX40L, 4-1BBL, and TNF-related apoptosis-inducing ligand (TRAIL), but not C

155 In H460 cells, significant release of TNF-related apoptosis-inducing ligand (TRAIL), but not T

156 phenotype defined by increased expression of TNF-related apoptosis-inducing ligand (TRAIL), CD38, and

157 e to tumor necrosis factor alpha (TNFalpha), TNF-related apoptosis-inducing ligand (TRAIL), etoposide

158 Recent reports demonstrate that TNF-related apoptosis-inducing ligand (TRAIL), interacti

159 in (OPG), a soluble receptor of the cytokine TNF-related apoptosis-inducing ligand (TRAIL), is secret

160 , vascular endothelial growth factor (VEGF), TNF-related apoptosis-inducing ligand (TRAIL), TNF-alpha

161 1 and 2, active caspase 8, active caspase 3, TNF-related apoptosis-inducing ligand (TRAIL), TRAIL-R(D

162 as, TNF receptor-1 (TNFR1), or receptors for TNF-related apoptosis-inducing ligand (TRAIL), we invest

163 ent member of this family of proteins [e.g., TNF-related apoptosis-inducing ligand (TRAIL), which ind

164 sitive to killing by the proapoptotic ligand TNF-related apoptosis-inducing ligand (TRAIL), which is

165 ions, metastatic melanoma cell lines undergo TNF-related apoptosis-inducing ligand (TRAIL)- and tumor

166 at protects human colon carcinoma cells from TNF-related apoptosis-inducing ligand (TRAIL)-induced ap

167 ed to demonstrate the complete inhibition of TNF-related apoptosis-inducing ligand (TRAIL)-induced ap

168 y, miR-25 was shown to protect cells against TNF-related apoptosis-inducing ligand (TRAIL)-induced ap

169 Therapeutic agents that activate TNF-related apoptosis-inducing ligand (TRAIL)-induced ap

170 For TNF-related apoptosis-inducing ligand (TRAIL)-mediated a

171 tosis was also observed in 17AAG-treated and TNF-related apoptosis-inducing ligand (TRAIL)-treated ca

172 thus blocking apoptosis initiated by Fas and TNF-related apoptosis-inducing ligand (TRAIL).

173 ed cells to apoptosis induced by TNF and the TNF-related apoptosis-inducing ligand (TRAIL).

174 id arthritis express receptors that can bind TNF-related apoptosis-inducing ligand (TRAIL).

175 c (AdsDR5), which is capable of neutralizing TNF-related apoptosis-inducing ligand (TRAIL).

176 agonistic anti-Fas monoclonal antibody, and TNF-related apoptosis-inducing ligand (TRAIL).

177 and an IFN-dependent elevation of macrophage TNF-related apoptosis-inducing ligand (TRAIL).

178 ensitivity to tumor necrosis factor (TNF) or TNF-related apoptosis-inducing ligand (TRAIL).

179 tant to the novel selective cytotoxic agent, TNF-related apoptosis-inducing ligand (TRAIL).

180 ls were directly linked to the expression of TNF-related apoptosis-inducing ligand (TRAIL).

181 mming, partly because of the upregulation of TNF-related apoptosis-inducing ligand (TRAIL).

182 and radiotherapy and biologicals, including TNF-related apoptosis-inducing ligand (TRAIL).

183 tumor necrosis factor alpha (TNF-alpha) and TNF-related apoptosis-inducing ligand (TRAIL).

184 mulatory effects, including the induction of TNF-related apoptosis-inducing ligand (TRAIL)/Apo-2L on

185 Fas ligand (FasL) and TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L are

186 tosis induced by the TNF-alpha family member TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L.

187 contributes to CD4+ T cell apoptosis by the TNF-related apoptosis-inducing ligand (TRAIL)/death rece

188 TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) has

189 pa B activity and potentiate the activity of TNF-related apoptosis-inducing ligand (TRAIL/Apo2L), dex

190 the chemical inhibitor wortmannin increased TNF-related apoptosis-inducing ligand (TRAIL; Apo2) mRNA

191 We now show that the binding of TNF-related, apoptosis-inducing ligand (TRAIL) to its ce

192 ctivated by the death receptor pathway, is a TNF-related, apoptosis-inducing ligand (TRAIL)-induced l

193 ated killing express the death receptor DR5 (TNF-related apoptosis-inducing ligand [TRAIL] receptor 2

194 or that is most closely related to mammalian TNF-related apoptosis-inducing ligand [TRAIL] receptors)

195 For TRAIL (TNF-related apoptosis-inducing ligand) variability manif

196 inducible nitric oxide synthase, IL-23, and TNF-related apoptosis-inducing ligand were present in IF

197 lymphotoxin-alpha(1)beta(2), Fas ligand, and TNF-related apoptosis inducing ligand; while cancer cell