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1 asers to increase sample throughput of axial TOF MS instruments, obtaining a high-resolution image st
2 horesis/time-of-flight mass spectrometry (CE/TOF-MS) methodology for these labeled glycans, which com
3 icability of two different platforms (LC-ESI-TOF MS and LC-ESI-IT MS) as powerful tools for the chara
4 lutive chromatographic method coupled to ESI-TOF MS (for initial characterisation purposes) and coupl
5 n time-of-flight mass spectrometry (HPLC-ESI-TOF-MS) method has been applied for the separation, iden
7 ray time-of-flight mass spectrometry (LC-ESI-TOF-MS) has been applied to screen bioactive metabolites
9 zation time-of-flight mass spectrometry (ESI-TOF-MS) to derive the reaction mechanism and to obtain t
10 zation time-of-flight mass spectrometry (ESI-TOF-MS), thereby demonstrating the influence of differen
12 ography-time-of-flight mass spectrometry (GC-TOF-MS) based metabolomics combined with partial least s
15 th time-of-flight mass spectrometry (GC x GC-TOF-MS) measurements, each with an associated match fact
16 hy-time-of-flight mass spectrometry (GC x GC-TOF-MS), and their identity were confirmed by comparison
18 ography/time-of-flight mass spectrometry (GC/TOF-MS), here used to examine the S. cerevisiae metabolo
19 sample processing of data acquired by GCxGC-TOF MS for the identification of potentially novel persi
20 aphy time-of-flight mass spectrometry (GCxGC-TOF MS) is considered as a powerful analytical platform
24 dentification power of PI coupled with GCxGC-TOF-MS is the first report covering volatiles to low-vol
25 aselines, and GC(2)MS is able to align GCxGC/TOF-MS data sets acquired under different experimental c
29 aphy time-of-flight mass spectrometry (GCxGC/TOF-MS) is superior for chromatographic separation and p
31 GC(2)MS then aligns the blobs of two GCxGC/TOF-MS data sets according to their distance and similar
32 ormance of GC(2)MS was evaluated using GCxGC/TOF-MS data sets of Angelica sinensis compounds acquired
34 olution time-of-flight mass spectrometer (HR TOF MS), under the challenging conditions of a flow-modu
37 time-of-flight mass spectrometry (LAESI-IMS-TOF-MS) was used for the analysis of synthetic polymers
39 on-trap time-of-flight mass spectrometer (IT-TOF-MS) for the separation and identification of constit
40 a time-of-flight mass spectrometer (UPLC-IT-TOF-MS) that allowed the characterization of the toxin p
43 e-of-flight mass spectrometric detection (LC-TOF-MS) and LC with tandem MS (MS/MS) detection have bee
45 hat accurately detects the pure ions of a LC/TOF-MS profile to extract pure ion chromatograms and det
46 ography/time-of-flight mass spectrometry (LC/TOF-MS) chromatograms of 228 plasma samples and 23 poole
47 ography/time-of-flight mass spectrometry (LC/TOF-MS) ion signals in a complex biological sample remai
49 zation time-of-flight mass spectrometry (LDI-TOF MS) studies of the crystalline samples show intense
50 nning mirror, a laboratory-built axial MALDI TOF MS instrument utilizing a 4-kHz UV laser recorded a
51 tion time-of-flight mass spectrometry (MALDI TOF MS) imaging of surfaces and tissues is a rapidly evo
67 grees C using a spectrophotometer) and MALDI-TOF MS (both the standard result output and by visual sp
68 standardized culture, extraction, and MALDI-TOF MS analysis, isolates were identified using score cu
69 value (NPV) of MALDI-TOF MS alone and MALDI-TOF MS coupled with UA were 86.6% versus 93.4% (chi(2) =
70 cation (CONV), (ii) manual plating and MALDI-TOF MS identification (MALDI), (iii) MALDI-TOF MS identi
72 ity and that the combination of UA and MALDI-TOF MS provided an accurate and rapid detection and iden
75 ant factors that must be considered as MALDI-TOF MS moves into applications beyond microbial identifi
76 fication by use of the Bruker Biotyper MALDI-TOF MS system, including density of organism spotting on
77 s study evaluated the Bruker Biotyper (MALDI-TOF MS) system for the identification of clinically rele
78 (0.9%) isolates were misidentified by MALDI-TOF MS (including Aspergillus amoenus [n = 2] and Asperg
79 the substitution has been validated by MALDI-TOF MS analysis of the functionalized precursors and FT-
81 y testing of the samples identified by MALDI-TOF MS produced an overall categorical agreement of 99.2
83 ng bioconjugates were characterized by MALDI-TOF MS, differential scanning calorimetry (DSC), fluores
84 for both DP8 and DP9 were confirmed by MALDI-TOF MS, including two of high confidence, calreticulin a
93 terial and yeast isolates prepared for MALDI-TOF MS identification can be repeatedly analyzed without
95 I-TOF MS identification (MALDI), (iii) MALDI-TOF MS identification and early phase implementation of
96 elevant Nocardia spp. and to implement MALDI-TOF MS libraries developed by single laboratories across
97 ed characteristic isotopic patterns in MALDI-TOF MS, and both a fragmentation product y1 ion correspo
98 implementation of TLA (TLA1), and (iv) MALDI-TOF MS identification and late phase implementation of T
99 ty of the Bruker Biotyper and Vitek MS MALDI-TOF MS systems and their in vitro diagnostic (IVD), rese
100 red, demonstrate the value of this new MALDI-TOF MS method as an analytical tool for the identificati
101 s have been characterized by (1)H NMR, MALDI-TOF MS, steady-state absorption and emission spectroscop
102 dia isolates, and NIH and OSU Nocardia MALDI-TOF MS libraries were distributed to three centers.
103 supplementation of the Bruker Nocardia MALDI-TOF MS library with both the OSU and NIH libraries incre
104 and negative predictive value (NPV) of MALDI-TOF MS alone and MALDI-TOF MS coupled with UA were 86.6%
105 is study was to evaluate the impact of MALDI-TOF MS alone versus MALDI-TOF MS combined with real-time
107 aluated the capacity of combination of MALDI-TOF MS and urine analysis (UA) for direct detection and
108 Our work highlights applications of MALDI-TOF MS beyond identification, focusing on mycobacterial
111 ee sites, while specificity and NPV of MALDI-TOF MS for males were significantly higher than those fo
113 s review discusses the various uses of MALDI-TOF MS for the identification and susceptibility testing
114 his work, we report the specificity of MALDI-TOF MS for the identification of 162 Mycobacterium speci
115 ecent literature describing the use of MALDI-TOF MS for the routine identification of a variety of ye
116 United States demonstrating the use of MALDI-TOF MS to facilitate the clinical diagnosis in patients
117 in the databases and in the ability of MALDI-TOF MS to rapidly identify slowly growing mycobacteria a
118 specificity study, the performance of MALDI-TOF MS was directly compared with that of 16S rRNA gene
120 peptides at other times of processing, MALDI-TOF MS was also employed as a fast and easier technique.
122 tion-time-of-flight mass spectrometry (MALDI-TOF MS) after enzymatic digestion of the polysaccharide
125 tion-time of flight mass spectrometry (MALDI-TOF MS) and BD Kiestra total laboratory automation (TLA)
126 tion-time of flight mass spectrometry (MALDI-TOF MS) and evaluated the capacity of combination of MAL
127 tion-time-of flight mass spectrometry (MALDI-TOF MS) assay was developed to detect these and six prev
128 tion-time of flight mass spectrometry (MALDI-TOF MS) can be used as a method for the rapid identifica
129 tion-time of flight mass spectrometry (MALDI-TOF MS) decreases the time to organism identification an
130 tion-time of flight mass spectrometry (MALDI-TOF MS) directly from positive blood cultures using prew
133 tion-time of flight mass spectrometry (MALDI-TOF MS) for group B streptococcus (GBS) identification,
134 tion-time of flight mass spectrometry (MALDI-TOF MS) for identification of Fusobacterium nucleatum su
135 tion-time of flight mass spectrometry (MALDI-TOF MS) for rapid organism identification and dedicating
136 tion-time of flight mass spectrometry (MALDI-TOF MS) for the identification of bacteria and yeasts is
137 tion time of flight mass spectrometry (MALDI-TOF MS) for the identification of Exophiala species.
138 tion-time of flight mass spectrometry (MALDI-TOF MS) for the identification of NTM isolated on RGM me
139 tion-time of flight mass spectrometry (MALDI-TOF MS) has become the standard for routine bacterial sp
140 tion-time of flight mass spectrometry (MALDI-TOF MS) has emerged as a rapid and accurate method for i
141 tion-time of flight mass spectrometry (MALDI-TOF MS) has recently been described as a fast and inexpe
142 tion-time of flight mass spectrometry (MALDI-TOF MS) has recently been reported to be a reliable and
143 tion-time of flight mass spectrometry (MALDI-TOF MS) has reduced the time to identification of cultur
144 tion-time of flight mass spectrometry (MALDI-TOF MS) has revolutionized clinical microbiology for iso
145 tion-time of flight mass spectrometry (MALDI-TOF MS) identification, and score interpretation, using
146 tion-time of flight mass spectrometry (MALDI-TOF MS) identified Staphylococcus lugdunensis to be a mo
147 tion-time of flight mass spectrometry (MALDI-TOF MS) in clinical microbiology has revolutionized spec
148 tion-time of flight mass spectrometry (MALDI-TOF MS) in conjunction with active antimicrobial steward
149 tion time of flight mass spectrometry (MALDI-TOF MS) in the identification of Haemophilus, Aggregatib
150 tion-time of flight mass spectrometry (MALDI-TOF MS) is a powerful tool for the rapid and highly accu
151 tion time of flight mass spectrometry (MALDI-TOF MS) is a rapid and accurate method of identifying mi
152 tion time-of-flight mass spectrometry (MALDI-TOF MS) is currently changing the clinical routine for i
153 tion time-of-flight mass spectrometry (MALDI-TOF MS) is frequently used for the characterization of c
154 tion time-of-flight mass spectrometry (MALDI-TOF MS) platforms in the medical microbiological practic
155 tion-time of flight mass spectrometry (MALDI-TOF MS) sample preparation methods, including the direct
157 sorption/ionization mass spectrometry (MALDI-TOF MS) that allows quantification of pure or mixed dete
158 tion-time of flight mass spectrometry (MALDI-TOF MS) to detect pKpQIL_p019 (p019)-an approximately 11
159 tion-time of flight mass spectrometry (MALDI-TOF MS) was used to confirm selectivity of imprints.
160 tion-time of flight mass spectrometry (MALDI-TOF MS) with Sepsityper processing (Bruker Daltonics, Bi
162 tion-time of flight mass spectrometry (MALDI-TOF MS), sequencing of eight genes in the GPL locus, and
163 tion-time of flight mass spectrometry (MALDI-TOF MS), suspicious isolates are now routinely identifie
164 tion time-of-flight mass spectrometry (MALDI-TOF MS)-based assay was developed that could directly fo
165 tion-time of flight mass spectrometry (MALDI-TOF MS)-based identifications of the flown and stationar
174 me-of-flight tandem mass spectrometry (MALDI-TOF MS/MS), we now reveal that actually up to five fucos
175 tion time-of-flight mass spectrometry (MALDI-TOF MS; 14 SNPs) in at least 1303 Caucasian children (65
178 ynamic range and higher precision than MALDI-TOF MS, while still generating results in a similar time
182 r aerobic actinomycetes using both the MALDI-TOF MS manufacturer's supplied database(s) and a custom
183 142,532.69, versus $68,886.51 with the MALDI-TOF MS method, resulting in a laboratory savings of $73,
184 Plasmid identification using this MALDI-TOF MS method was accomplished in as little as 10 min fr
185 AMS intervention included: real-time MALDI-TOF MS pharmacist notification and prospective AMS provi
186 cobacteria require extraction prior to MALDI-TOF MS analysis, previously published protocols have bee
190 l microbiology laboratories to utilize MALDI-TOF MS for the rapid identification of clinically releva
191 he impact of MALDI-TOF MS alone versus MALDI-TOF MS combined with real-time, pharmacist-driven, antim
192 positive blood cultures identified via MALDI-TOF MS combined with prospective AMS intervention compar
193 ost of performing the bioMerieux Vitek MALDI-TOF MS with conventional microbiological methods to dete
194 gainst all Exophiala isolates in vitro MALDI-TOF MS successfully distinguished all 18 species and ide
195 ptibility testing might be useful when MALDI-TOF MS results in an organism identification, and it mig
196 al outcomes, rapid identification with MALDI-TOF MS combined with real-time AMS intervention is more
198 n an off-line combination of CIEF with MALDI-TOF MS was employed for rapid and reliable identificatio
202 chniques such as RP-HPLC-UV, GFAAS and MALDI-TOF-MS allowed the identification of several proteins bo
203 thod for sialic acid stabilization and MALDI-TOF-MS analysis, to allow direct modification of impure
205 applied microchip electrophoresis and MALDI-TOF-MS-based glycomic procedures to 20 control serum sam
206 nd E nterobacter spp. were analyzed by MALDI-TOF-MS in negative ion mode to obtain glycolipid mass sp
207 solid phase extraction and analyzed by MALDI-TOF-MS in reflectron positive mode with 2,5-dihydroxyben
210 hed an expeditious method that couples MALDI-TOF-MS with a simple dilution method to quantify curcumi
211 onisation properties and resolution in MALDI-TOF-MS, these phosphopeptides were identified as suitabl
213 -assisted laser desorption/ionization (MALDI-TOF-MS) for determination of Cu, Fe, Mn and Zn and ident
214 B and 1.2 x 10(5) J/m(2) UVA), neither MALDI-TOF-MS nor RT-qPCR detected significant decreases in the
216 chip technology (24 polymorphisms) or MALDI-TOF-MS (40 polymorphisms) in at least 1303 German childr
217 Following UV254 exposure, quantitative MALDI-TOF-MS detected significantly more RNA modifications tha
219 tion time-of-flight mass spectrometry (MALDI-TOF-MS) analysis of high abundance proteins is gaining p
221 tion Time of Flight Mass Spectrometry (MALDI-TOF-MS) biotyping to deliver rapid and accurate strain s
222 with time-of-flight mass spectrometry (MALDI-TOF-MS) has been used to analyse various molecules (incl
223 tion time-of-flight mass spectrometry (MALDI-TOF-MS) has successfully been used for the analysis of h
224 tion time-of-flight mass spectrometry (MALDI-TOF-MS) is a valuable tool for glycan characterization a
226 tion time-of-flight mass spectrometry (MALDI-TOF-MS) method and corresponding mathematic matrix to de
227 tion time-of-flight mass spectrometry (MALDI-TOF-MS) to study deamidation in wool textiles, we identi
231 ation with minimal side reactions: the MALDI-TOF-MS profiles obtained were in good agreement with hyd
232 cylglycerol) in complex mixtures using MALDI-TOF-MS with fractional factorial design (FFD) and Pareto
234 y RNA pulldown experiments followed by MALDI/TOF-MS analysis, we identified heterogeneous nuclear rib
237 for wide m/z range applications, whereas MR-TOF MS can provide advantages in a "zoom-in" mode in whi
238 prising both conventional time-of-flight MS (TOF-MS) and nano-electromechanical systems-based MS (NEM
239 time-of-flight mass spectrometry (IR-MALDI-o-TOF MS) in combination with collision-induced dissociati
241 In this paper, we present results of a PI-TOF-MS study at the Advanced Light Source at Lawrence Be
242 ble to those with other synchrotron-based PI-TOF-MS reactors, and it is anticipated that this high pr
243 S research to include synchrotron sourced PI-TOF-MS required a radical reconception of the shock tube
244 ization time-of-flight mass spectrometry (PI-TOF-MS) is an important technique in combustion chemistr
245 action-time-of-flight-mass spectrometer (PTR-TOF-MS) were compared to BEFs reported in previous studi
248 is was performed using hybrid quadrupole (Q) TOF MS with an atmospheric pressure chemical ionization
249 cation and multivariate analysis to UHPLC-(Q)TOF MS data acquired in both, positive and negative ioni
255 ocol starts from untargeted metabolomic LC-Q-TOF-MS data that have been analyzed with the bioinformat
256 upole time-of-flight mass spectrometry (LC-Q-TOF-MS) was utilized to acquire metabolic profiles of mu
257 upole time-of-flight mass spectrometry (LC-Q-TOF-MS), hundreds to thousands of peaks with a unique m/
261 upole time-of-flight mass spectrometry (LC/Q-TOF-MS) and triple quadrupole mass spectrometry (LC/MS-M
266 of the OxPLs a recently introduced MALDI-QIT-TOF-MS/MS platform was employed and cross-validated by L
267 tored by UV-Vis spectroscopy and LC-ESI-(Qq)-TOF-MS-DAD, enabling the identification of some intermed
268 PD studies that the sensitivity of the REMPI-TOF-MS is comparable to commercial EI-Q-MS solutions and
270 al rituximab sample shows that online sLCxLC-TOF-MS can be used to rapidly characterize mAb samples,
272 med with a time-of-flight mass spectrometer (TOF-MS) to allow for a comprehensive evaluation of the o
273 ionization time-of-flight mass spectrometry (TOF-MS) allows the detection of thousands of compounds.
274 apply LIAD time-of-flight mass spectrometry (TOF-MS) to the natural biochromophores chlorophyll, hemi
277 ctrometry with NO(+) as the reagent ion (SRI-TOF-MS (NO(+))) was applied for near real-time monitorin
278 ubstantial increase in the throughput of the TOF MS-based tissue imaging can be achieved by incorpora
279 electrospray ionization (ESI) source to the TOF MS analyzer by means of a linear SLIM, demonstrating
280 gh sensitivity and high mass accuracy of the TOF-MS revealed the presence of more than 70 glycans.
282 issue sections was performed using MALDI-TOF/TOF MS in both negative and positive ionization modes af
283 time-of-flight mass spectrometry (MALDI-TOF/TOF MS) were used to assess the different protein expres
286 /time-of-flight mass spectrometry (MALDI-TOF/TOF-MS) for sequential identification of the peptide.
290 paper, the potential of Synapt G2-S (Q-TWIM-TOF MS) has been investigated for sensitive and specific
292 combined metabolomic approach based on UHPLC-TOF-MS profiling and (1)H NMR fingerprinting to highligh
294 aphy/time-of-flight mass spectrometry (UHPLC/TOF-MS), was used for the analysis of 60 pesticides in v
296 raphy time-of-flight mass spectrometry (UPLC TOF-MS), Fourier transform ion cyclotron resonance (FT-I
300 S(+) radical scavenging assay and LC-MS with TOF-MS for compositional analysis of the most potent ant
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