ライフサイエンスコーパス: TOFMS

1 Particularly, GC(3)/TOFMS achieved a combined (2)D x (3)D peak capacity rang

2 The GC(3)/TOFMS instrument experimentally achieved total peak capa

3 f-flight mass spectrometric detection (GC(3)/TOFMS) is described.

4 the 44 peaks, 25 were identified by use of a TOFMS library created for this study; another 11 were id

5 nd retrofitted to an orthogonal acceleration TOFMS.

6 mpling duty cycle of orthogonal acceleration TOFMS.

7 atographic separation of most compounds, and TOFMS allows mass spectral deconvolution of coeluting co

8 The geometric mean LOQs using the qMS and TOFMS were 4 and 3 ng/g ginseng, respectively.

9 e, we applied MCF derivatization and GC-APCI-TOFMS to the detection of changes in abundance of metabo

10 fference) that they could not be resolved by TOFMS alone.

11 ne chemical ionization mass spectrometry (CI-TOFMS) where formamide, isocyanic acid as well as higher

12 IMS-in-source collision induced dissociation-TOFMS (FISCID-MS) method requires only minor modificatio

13 ation-time-of-flight mass spectrometry (ENCI-TOFMS).

14 signal intensity of m/z in sheathless CE/ESI-TOFMS at pH 6.7 is approximately 50 times higher than th

15 ion time-of-flight mass spectrometry (CE/ESI-TOFMS).

16 of-flight mass spectrometry detector (LC-ESI-TOFMS) to identify fluorinated compounds in natural wate

17 using internal standards in the on-line ESI-TOFMS process.

18 lues are then obtained upon the basis of ESI-TOFMS so that an image of isolectric point (pI) versus M

19 The ESI-TOFMS analysis of SLTx-AB(5) revealed the complex remain

20 eved by coupling pressure-assisted CE to ESI-TOFMS using the described sheathless electrospray emitte

21 entional sample preparations using UHPLC-ESI-TOFMS analyses.

22 Compared with UHPLC-ESI-TOFMS, analysis by the nanoplatform enabled detection of

23 amples and to enhance column selectivity for TOFMS characterization in cases in which peak overlap is

24 C/min programming rate were explored for GC-TOFMS, specifically a 20 m, 100 mum inner diameter (i.d.

25 Analysis of GC-TOFMS data by this method produces what is referred to a

26 To optimize GC-TOFMS separations collected with a commercial instrument

27 ography-time-of-flight mass spectrometry (GC-TOFMS) and applied to the fast separation of complex sam

28 ography time-of-flight mass spectrometry (GC-TOFMS) is presented that significantly facilitates separ

29 These results demonstrate that GC x GC-TOFMS analysis in combination with a random forest techn

30 analyte signals in a subsection of a GC x GC-TOFMS chromatogram (i.e., for analyses when identities o

31 n of signal from a target analyte in GC x GC-TOFMS data (i.e., for an analysis in which the identity

32 sses algorithmically reduces complex GC x GC-TOFMS data sets to find class distinguishing chemical fe

33 We use real experimental GC x GC-TOFMS data to demonstrate the broad applicability of the

34 an appropriate number of factors in GC x GC-TOFMS data, demonstrated for a target analyte of interes

35 predicted by N-PLS and identified by GC x GC-TOFMS were confirmed using quantitative structure-activi

36 hy-time-of-flight mass spectrometry (GC x GC-TOFMS) data set to the bioassay data obtained from norma

37 th time-of-flight mass spectrometry (GC x GC-TOFMS) is a versatile instrumental platform capable of c

38 s with multichannel detection (e.g., GC x GC-TOFMS) or multiple samples (or replicates) of 2D data.

39 to time-of-flight mass spectrometry (GC x GC-TOFMS) was used with discovery-based data mining algorit

40 th time-of-flight mass spectrometry (GC x GC-TOFMS).

41 flight mass spectrometric detection (GC x GC-TOFMS).

42 th time-of-flight mass spectrometry (GC x GC-TOFMS).

43 time-of-flight mass spectrometry (TD-GC x GC-TOFMS).

44 t with several target analytes using GC x GC-TOFMS.

45 rming the feasibility of the new dynHS-TD-GC/TOFMS approach for routine analysis.

46 ime-of-flight mass spectrometry (dynHS-TD-GC/TOFMS) for the simultaneous quantitation of these boar t

47 t, and HVHF fluids had been available, GCxGC-TOFMS might have fingerprinted the contamination source.

48 d to contain 44 terpenes identified by GCxGC-TOFMS.

49 research was to develop a nontargeted GCxGC-TOFMS approach to characterize petroleum metabolites in

50 d to time-of-flight mass spectrometry (GCxGC-TOFMS), an unresolved complex mixture of organic compoun

51 e-of-flight mass spectrometry (HS-SPME/GCxGC-TOFMS).

52 GCxGC/TOFMS allowed identification of 220 compounds including

53 GCxGC/TOFMS allows more detailed study of the volatile profile

54 GCxGC/TOFMS analyses and QDA have shown that a larger spacing

55 of-flight mass spectrometry detection (GCxGC/TOFMS) and chemometric tools.

56 f-flight mass spectrometric detection (GCxGC/TOFMS) proved to be appropriate for this first simultane

57 of-flight mass spectrometry detection (GCxGC/TOFMS) was used to analyse the volatiles in five types o

58 A detailed examination of GCxGC/TOFMS data showed that the use of one-dimensional gas ch

59 with time-of-flight mass spectrometry (GCxGC/TOFMS) on plasma from patients with S. Typhi and S. Para

60 profile and sensory perception through GCxGC/TOFMS, QDA, GC-FID, GC/MS, and GC-O.

61 on of some of them was possible due to GCxGC/TOFMS performance.

62 00 scans/s or greater) of current generation TOFMS detectors.

63 The combination of the HPLC-FTMS(n) and HPLC-TOFMS-SPE-NMR platforms results in the efficient identif

64 onance spectroscopy (NMR) measurements (HPLC-TOFMS-SPE-NMR).

65 ne-dimensional (1D)-(1)H NMR spectra of HPLC-TOFMS-SPE-trapped compounds, we elucidated the structure

66 Mean recoveries using GC-HR-TOFMS were 93, 85, and 81% with mean standard deviations

67 tion time-of-flight mass spectrometry (GC-HR-TOFMS).

68 HT-TOFMS was able to sample peaks having widths in the mill

69 ansform time-of-flight mass spectrometry (HT-TOFMS) is a promising detector for any capillary-format

70 urized-capillary electrophoresis (pCE) to HT-TOFMS.

71 he visual interpretation of the data, LA-ICP-TOFMS data were projected onto the mu-CT voxels represen

72 s performed to spatially align the 2D LA-ICP-TOFMS images relative to the corresponding slices of the

73 To demonstrate the potential of 3D LA-ICP-TOFMS imaging, high-resolution multielement images of a

74 thin sections that were subjected to LA-ICP-TOFMS imaging.

75 sma-time-of-flight mass spectrometry (LA-ICP-TOFMS) and laboratory-based absorption microcomputed tom

76 sma time-of-flight mass spectrometry (LA-ICP-TOFMS) for high-speed, high-resolution, quantitative thr

77 plasma time-of-flight mass spectrometer (ICP-TOFMS) is described.

78 plasma-time-of-flight mass spectrometry (ICP-TOFMS) to provide full-spectrum elemental imaging at hig

79 The ability of the ICP-TOFMS to produce complete elemental mass spectra at high

80 laser-spot diameter of 5 mum coupled to ICP-TOFMS.

81 um i.d. RTX-5 column with a LECO Pegasus III TOFMS.

82 obility-time-of-flight mass spectrometry (IM-TOFMS) was used to identify and correlate response ions

83 value-added information provided by UPLC-IM-TOFMS makes it a promising analytical technique for anal

84 ty time-of-flight mass spectrometry (UPLC-IM-TOFMS) to corroborate the separation of distinct NA spec

85 ty time-of-flight mass spectrometry (UPLC-IM-TOFMS), integrating traveling wave ion mobility spectrom

86 ions were separated and identified using IM-TOFMS.

87 y advantage of this strategy is that the IM/ TOFMS approach allows the relative abundances of individ

88 erent sequences are assessed by comparing IM/TOFMS data for those components that pass through the co

89 obility/time-of-flight mass spectrometry (IM/TOFMS) analysis has been used to investigate the binding

90 The MP IMS-TOFMS instrument has been shown to reliably detect pepti

91 ometry-time-of-flight mass spectrometry (IMS-TOFMS) has been increasingly used in analysis of complex

92 an analog-to-digital converter, into the IMS-TOFMS system for the high-throughput analysis of highly

93 A major challenge is to transform IMS-TOFMS to a high-sensitivity, high-throughput platform, f

94 cover a broad range of polarity using MALDI TOFMS.

95 assisted laser desorption-ionization (MALDI) TOFMS peptide mapping and intact MW so that a standard m

96 Transfer into the elution buffer and MALDI-TOFMS detection was achieved from 5 microL of starting s

97 this first-time coupling of ThFFF and MALDI-TOFMS, compatibility issues were addressed and optimum c

98 n the MW distribution data obtained by MALDI-TOFMS and ThFFF.

99 ration by ThFFF and analyzed either by MALDI-TOFMS or reinjection into the ThFFF system.

100 actions were collected and analyzed by MALDI-TOFMS to determine the molecular weights and peptide map

101 ose beads and subsequently analyzed by MALDI-TOFMS using a curved-field reflectron.

102 ted analyte can be studied directly by MALDI-TOFMS, or subjected to proteolytic digestion for protein

103 wash was concentrated and analyzed by MALDI-TOFMS.

104 f purified proteins were determined by MALDI-TOFMS.

105 re followed by delayed extraction (DE) MALDI-TOFMS is presented.

106 microfabricated PCR instrument and DE-MALDI-TOFMS, a complete genotyping assay can be performed in u

107 al composition fractions essential for MALDI-TOFMS analyses.

108 from 1-10 ThFFF runs were combined for MALDI-TOFMS analysis.

109 Sample preparation for MALDI-TOFMS was enhanced through the use of hydrophobic/hydrop

110 On the other hand, MALDI-TOFMS's ability to directly measure molecular weight all

111 zed previously by solution preparation MALDI-TOFMS, were used to evaluate the various solvent-free pr

112 ethods were developed to allow routine MALDI-TOFMS analyses of polystyrene polymers up to 575 kDa.

113 tion time-of-flight mass spectrometer (MALDI-TOFMS) apparatus and the on-chip digestion followed by e

114 tion time-of-flight mass spectrometry (MALDI-TOFMS) have been coupled to yield a powerful combination

115 tion time-of-flight mass spectrometry (MALDI-TOFMS) method was developed for the analysis of underiva

116 tion time-of-flight mass spectrometry (MALDI-TOFMS) sample preparation methods for the characterizati

117 tion time-of-flight mass spectrometry (MALDI-TOFMS) targets.

118 tion time-of-flight mass spectrometry (MALDI-TOFMS).

119 tion time-of-flight mass spectrometry (MALDI-TOFMS).

120 tion time-of-flight mass spectrometry (MALDI-TOFMS).

121 tion-time-of-flight mass spectrometry (MALDI-TOFMS).

122 y techniques, but this work shows that MALDI-TOFMS using DCTB has advantages over these techniques, p

123 The application of ThFFF/MALDI-TOFMS to polydisperse polymers and polymer mixtures was

124 Progress in high-throughput MALDI-TOFMS analysis, especially in proteome applications, req

125 ein:matrix ratios, we were able to use MALDI-TOFMS to detect four bacterially expressed hydrophobic p

126 ependent analysis of methylation using MALDI-TOFMS clearly showed that both the presence and relative

127 t is demonstrated that NP RP HPLC with MALDI-TOFMS detection may serve as a rapid means of detecting

128 The GC-MPT-TOFMS system offered equal sensitivity for I, Br, and Cl

129 The GC-MPT-TOFMS system offered excellent stability over the course

130 yze urine by splitless nanoflowUHPLC-nanoESI-TOFMS (nUHPLC-nESI-TOFMS) after preconcentration by soli

131 ty arising from use of splitless nUHPLC-nESI-TOFMS analyses of SPE-concentrated samples represents a

132 Analyses of SPE preparations by nUHPLC-nESI-TOFMS revealed excellent retention time repeatability wi

133 ess nanoflowUHPLC-nanoESI-TOFMS (nUHPLC-nESI-TOFMS) after preconcentration by solid-phase extraction

134 tification of potential sources, nontargeted TOFMS analysis, molecular feature extraction (MFE) of sa

135 portion of the eluent (10%) was taken for oa-TOFMS for identification.

136 Analyte desorption and the subsequent PI-TOFMS detection step only lasts ten seconds.

137 tion time-of-flight mass spectrometry (TD-PI-TOFMS).

138 desorbed and directly transferred to the PI-TOFMS ion source.

139 tal LA signal within 9 ms, and the prototype TOFMS instrument enables simultaneous and representative

140 acteristic fragmentation pattern by hybrid Q-TOFMS offers a distinct advantage for the identification

141 leration time-of-flight mass spectrometry (Q-TOFMS).

142 igh-throughput ultra HPLC (UHPLC)-quadrupole TOFMS (qTOFMS) method, processed to systematically infer

143 ween 40 pairs of simultaneous 5-min GC-REMPI-TOFMS measurements of 1,2,4-trichlorobenzene and 5 min c

144 The GC-REMPI-TOFMS system can be used to provide frequent measures of

145 - time-of-flight mass spectrometry (GC-REMPI-TOFMS) system were compared over 5-min periods with conv

146 Furthermore, the NTD-REMPI-TOFMS setup was tested for breath gas taken from a mecha

147 tion time-of-flight mass spectrometry (REMPI-TOFMS) technique has been applied to the exhaust gas str

148 The high isomer selectivity of the REMPI-TOFMS instrument provided data for individual xylene iso

149 ing a GC column separator ahead of the REMPI-TOFMS.

150 resolution) as demonstrated here using REMPI-TOFMS.

151 latile organic compounds obtained with REMPI-TOFMS and conventional extractive sampling.

152 the sample introduction techniques for REMPI/TOFMS, the analyte molecules are adsorbed at the tip of

153 tion/time-of-flight mass spectrometry (REMPI/TOFMS) was developed for the analysis of product ions fo

154 sor into a time-of-flight mass spectrometer (TOFMS) for simultaneous thermal and speciation measureme

155 celeration time-of-flight mass spectrometer (TOFMS) is explored for elemental analysis.

156 reflectron time-of-flight mass spectrometer (TOFMS) that provides a mass spectrum at every pixel of a

157 resolution time-of-flight mass spectrometer (TOFMS) that provides improved selectivity and accurate e

158 faced to a time-of-flight mass spectrometer (TOFMS).

159 (CID) and time-of-flight mass spectrometry (TOFMS) analysis.

160 celeration time-of-flight mass spectrometry (TOFMS) based on the superimposition of a magnetic field

161 on (MALDI) time-of-flight mass spectrometry (TOFMS) following separation by reversed-phase high-perfo

162 coupled to time-of-flight mass spectrometry (TOFMS) for the detection of halogenated hydrocarbons sep

163 resolution time-of-flight mass spectrometry (TOFMS) for the identification of bioactives.

164 d to REMPI time-of-flight mass spectrometry (TOFMS).

165 The TOFMS instrument uses time-array detection to obtain up

166 The TOFMS was operated with a spectral acquisition rate of 2

167 adjusted to enhance the capabilities of the TOFMS detector.

168 d with the 0.1 ms temporal resolution of the TOFMS provides a new measurement capability and insight

169 corporated into the extraction region of the TOFMS system to provide sample heating and thermal infor

170 /min, due to the flow rate constraint of the TOFMS).

171 rage and rapid simultaneous detection of the TOFMS, the element composition of individual particles c

172 provide a narrow injection pulse, while the TOFMS provided a data collection rate of 500 Hz, initial

173 eparation typically is not required with the TOFMS detection, and a pressure-tunable column ensemble

174 Analysis by UHPLC-TOFMS confirmed that the SILAAs were incorporated into p

175 lustrated using both 600-MHz 1H NMR and UPLC-TOFMS data obtained from control rat urine samples (n =

176 ectivities in the 3D separation coupled with TOFMS are illustrated through the separation and detecti