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1 TPP is homologous to Escherichia coli type I signal pept
2 TPP likely is a major contributor to these biological ac
3 TPP might also be a promising platform for tumor-specifi
4 r (CP), 3, prepared from S = 1/2 Co(TPP), 1 (TPP = 5,10,15,20-tetraphenylporphyrin dianion), and S =
5 e, we present an in-depth analysis of the 10 TPP genes and gene products in Arabidopsis (TPPA-TPPJ).
6 otal structural determination of Ag29(BDT)12(TPP)4, an atomically precise tetravalent nanocluster (NC
8 ment of GeCl2(dioxane) with Li2(TPP)(OEt2)2 (TPP = tetraphenylporphyrin) in THF yields Ge(TPP), the f
10 expression of this operon is regulated by a TPP-binding riboswitch via a feedback inhibition mechani
12 es indicate that many fungal species carry a TPP riboswitch with similar intron architecture, and the
13 we identified a gene cluster that encodes a TPP ABC transporter which consists of a TPP-binding prot
14 n, the structure shows that the protein is a TPP-binding protein, opening up many avenues for future
15 es a TPP ABC transporter which consists of a TPP-binding protein (TDE0143), a transmembrane permease
17 es cerevisiae) showed that all encode active TPP enzymes with an essential role for some conserved re
21 n at saturating concentrations of Mg(2+) and TPP, the P1 helix, as well as distal regions surrounding
24 ntioxidant, while the BODIPY fluorophore and TPP ensure partitioning within the inner mitochondrial m
26 and the density maps of the ligand-free and TPP+-bound forms of EmrE, we identify regions within the
28 gether, our studies suggest that thiamin and TPP function as important stress-response molecules that
31 11 genes encode proteins with both TPS- and TPP-like domains but only one of these (AtTPS1) appears
32 e site models (TPP)FeII(ImH)2 (FeIIImH) and (TPP)Fe(Im)(ImH) (FeIIIIm) have been examined in acetonit
35 irect interaction between substrates such as TPP(+) and the essential residue E14 in transmembrane he
36 xymethylpyrimidine pyrophosphate, as well as TPP, but with an identical alternative splicing mechanis
38 nalogue Mito-Met10, synthesized by attaching TPP(+) to Met via a 10-carbon aliphatic side chain, was
42 boswitch employs modular domains for binding TPP to form a platform for gene expression regulation.
54 on polymer (CP), 3, prepared from S = 1/2 Co(TPP), 1 (TPP = 5,10,15,20-tetraphenylporphyrin dianion),
56 ce hybrid repeat unit best formulated as [Co(TPP)](0.5+) hemication (Co(2.5+)) bound to a dithiadiazo
57 bsence of olefin substrates, reaction of [Co(TPP)] with ethyl styryldiazoacetate was found to generat
59 the molecular identification of the colonic TPP uptake system as the product of the SLC44A4 gene.
64 l tris(o-phenylenedioxy)cyclotriphosphazene (TPP) is used as ahost for organizing dipolar molecular r
66 , tris(o-phenylenedioxy)cyclotriphosphazine (TPP, 1), using differential scanning calorimetry, solid-
68 ng ribosome binding, whereas most eukaryotic TPP riboswitches are predicted to regulate gene expressi
69 en the widespread distribution of eukaryotic TPP riboswitches and the diversity of their locations in
70 operon is negatively regulated by exogenous TPP and is mediated by a TPP-sensing riboswitch (Td(thi-
71 TPP biosynthesis pathway and needs exogenous TPP for growth, suggesting that it may obtain exogenous
73 that is required for the uptake of exogenous TPP and that the expression of this operon is regulated
74 d a decreased ability to transport exogenous TPP, and the mutant failed to grow when exogenous TPP wa
78 iron meso-tetraphenylporphyrin chloride (Fe[TPP]Cl) complex in 1,1,1,3,3,3-hexafluoropropan-2-ol (HF
79 ustworthiness is payoff-maximizing will find TPP to be less net costly (for example, because mechanis
81 the WWTP ranged from 0.02 mg/day/person for TPP to 28.7 mg/day/person for TBOEP, whereas the emissio
82 0.17 +/- 0.064 muM; and highly specific for TPP and not affected by free thiamine, thiamine monophos
84 alternative splicing regulation by a fungal TPP riboswitch from Neurospora crassa, which is mostly l
85 d that combining BH3 mimetics and gamitrinib-TPP blunted cellular proliferation in a synergistic mann
88 stic investigations revealed that gamitrinib-TPP activated a PERK-dependent integrated stress respons
96 the hypothesis that the microbiota-generated TPP is absorbable and could contribute toward host thiam
99 ll confocal imaging studies showed the human TPP transporter protein to be expressed at the apical me
101 ted with triphenylphosphonium hydroethidine (TPP-HE), which forms the superoxide specific reporter hy
105 wo sensitization steps (Fe(III)TPP --> Fe(II)TPP, and Fe(II)TPP --> Fe(I)TPP) both occur in <200 fs.
106 or the first two sensitization steps (Fe(III)TPP --> Fe(II)TPP, and Fe(II)TPP --> Fe(I)TPP) both occu
107 gnetic six-coordinate purple N-bound Co(III)(TPP)(N-py-DTDA(-))(O horizontal lineSMe2) complex (lambd
108 ane affords bright green diamagnetic Co(III)(TPP)(N-py-DTDA(-)), 3b, with multiple MLCT bands in the
112 diagnose active TB for treatment initiation (TPP#1) and for a community-based triage or referral test
114 lphavbeta3-integrin antagonist IntegriSense, TPP exhibits a significantly higher tumor-to-background
115 Moreover, in contrast with IntegriSense, TPP reliably differentiates between tumor cells and cell
116 tors with transversely dipolar rotators into TPP channels is followed by solid-state nuclear magnetic
117 tosan (1-2.5%w/w) and BSA (0.25-10%w/w) into TPP solutions ranging in concentration from 0.1 to 10%w/
120 Direct interaction between (13)C-labeled TPP(+) and key residues within the EmrE dimer has been p
121 ate of membrane Hsp70, fluorescently labeled TPP is continuously internalized into syngeneic, spontan
123 A new BiLi porphyrin sandwich compound, LiBi(TPP)2 has been synthesized and characterized (TPP=tetrap
128 ate that plastidic SPI 1 (Plsp1) is the main TPP in Arabidopsis thaliana (Arabidopsis) although bioch
130 ributions within PDAC leads to microregional TPP values that vary on the hundred micron distance scal
131 transfer catalyst and manganese porphyrin Mn(TPP)Cl 1, reaction of sodium hypochlorite with different
133 is(histidine) cytochrome active site models (TPP)FeII(ImH)2 (FeIIImH) and (TPP)Fe(Im)(ImH) (FeIIIIm)
137 nts provide a formal reputational account of TPP, and demonstrate how the costs of punishing may be r
138 negligible concentration of the C-2 anion of TPP, but of course not with an enzyme in modern biology.
140 t the utilization of lower concentrations of TPP is a good approach to improve the protein retention
141 vealed the double mutant is nearly devoid of TPP and instead accumulates the precursor of the TPK rea
142 to protonophores; saturable as a function of TPP concentration, with an apparent Km of 0.17 +/- 0.064
144 n glioma xenografts to explore the impact of TPP moieties, linkers, bifunctional chelators (BFCs), an
145 ) are suitable BFCs for the 64Cu-labeling of TPP cations; (3) NOTA-Bn ( S-2-(4-thioureidobenzyl)-1,4,
149 we investigated the inhibitory properties of TPP I prosegment expressed and isolated from Escherichia
150 Interestingly, the inhibitory properties of TPP I prosegment with the introduced classic late infant
151 s, the antineoplastic activity and safety of TPP(+)C10 warrant further comprehensive evaluation.
154 ing mainly of thyrotoxic periodic paralysis (TPP) and sporadic periodic paralysis (SPP), is largely u
155 Thyrotoxic hypokalemic periodic paralysis (TPP) is characterized by acute attacks of weakness, hypo
157 dentified threonine phosphorylation pathway (TPP) share the property of secretory ATPase recruitment
158 ated with blended NPs composed of PLGA-b-PEG-TPP and a triblock copolymer containing a fluorescent qu
159 onsidering efficacy, the targeted PLGA-b-PEG-TPP NP provides a remarkable improvement in the drug the
160 iphenylphosphonium (TPP) polymer (PLGA-b-PEG-TPP) with either nontargeted PLGA-b-PEG-OH or PLGA-COOH.
165 phate FRs that included triphenyl phosphate (TPP), tris(4-butylphenyl) phosphate (TBPP), and a mix of
166 etween 4.14 ng/g dw for tripropyl phosphate (TPP) and 7290 ng/g dw for TBOEP; for ash, they were betw
168 omains of TPS and trehalose-6-phosphorylase (TPP) in tandem as a fused gene product of Escherichia co
169 nalyzed according to the IL28B polymorphism, TPP SVR rates did not reach statistically significant di
170 study investigated their total polyphenols (TPP), catechins, caffeine, gallic acid and theanine.
173 tumor cell-penetrating peptide-based probe (TPP) recognizes an epitope of Hsp70 that is exclusively
174 h Organization (WHO) target product profile (TPP) criteria for a detection test and triage test to ev
175 rank test p = 0.11); treatment per-protocol (TPP) 78.1% (95% CI: 0.65 to 0.86) and 53.5% (95% CI: 0.3
178 n the case of the thiamine 5'-pyrophosphate (TPP) riboswitch from the Escherichia coli thiM gene enco
184 r this control is via thiamin-pyrophosphate (TPP) riboswitches, regions of the mRNA to which TPP can
185 The structure shows thiamine pyrophosphate (TPP) and two calcium ions are bound to Cypl and give the
186 ucture of the native thiamine pyrophosphate (TPP) riboswitch aptamer domain and identified large chan
189 latory mechanisms of thiamine pyrophosphate (TPP) riboswitches and has not been fully characterized.
192 relationships of the thiamine pyrophosphate (TPP)-dependent family of enzymes was investigated by gen
200 ockdown and overexpression lines of a single TPP, AtTPPG, points to unique properties of individual T
201 have been examined in acetonitrile solvent (TPP = tetraphenylporphyrin, ImH = 4-methylimidazole).
204 ve probed the specific binding of substrates TPP(+) and MTP(+) to EmrE reconstituted into 1,2-dimyris
209 tudied were 5,10,15,20-tetraphenylporphyrin (TPP), 5,10,15,20-tetramesitylporphyrin (TMP), and 2,3,7,
210 yrins 1(P1) (P1 = meso-tetraphenylporphyrin (TPP)) and 1(P2) (P2 = 3,5-Di(t)Bu-ChenPhyrin) with organ
212 In 10% MeOH/H(2)O, the tetraphenylporphyrin (TPP) and 1,4,5,8-naphthalenetetracarboxylic acid diimide
213 para positions of the tetraphenylporphyrin (TPP) phenyls results in an important positive deviation
214 better mitochondrion-targeting molecule than TPP and 3mTPP (tris(2,4,6-trimethoxyphenyl)phosphonium);
224 MeOH, assembly is driven exclusively by the TPP ring, leading to the formation of nonspecific, unstr
225 resentative values of rate constants for the TPP derivative were k = 8.6 x 10(5) M(-1) s(-1) for styr
227 ion and concomitant folding processes in the TPP riboswitch that culminate in the regulation of gene
229 evidence that the rate-limiting step in the TPP(+) transport cycle is not the outward-inward conform
231 ondingly, we posit that such features of the TPP aptamer domain contribute directly to the mechanism
232 maging to probe the folding landscape of the TPP aptamer domain in the absence and presence of magnes
238 structural mechanism similar to that of the TPP riboswitch, including the guanine and adenine ribosw
239 provides insight into the plasticity of the TPP riboswitches but also shows that their maintenance i
241 as 2 degrees C broader in the absence of the TPP(+) substrate versus its presence, which suggested th
243 x, as well as distal regions surrounding the TPP-binding site, exhibit an unexpected degree of residu
248 The phylogeny is most parsimonious with the TPP enzymes having arisen from a homotetramer which subs
249 idylethanolamine (PEG-PE) conjugate with the TPP group attached to the distal end of the PEG block (T
257 the weaker binding state is able to bind to TPP, but is unable to form a tertiary docking interactio
266 e demonstrate the broad applicability of TPE-TPP to monitor amyloid fibril aggregation, including und
267 triphenylphosphonium) tetraphenylethene (TPE-TPP)) with aggregation-induced emission characteristics
269 ith phos-phines, such as triphenylphosphine (TPP), 1,2-bis(diphenylphosphino)ethane [DPPE], and tris(
270 f the smallest clusters, triphenylphosphine (TPP)-stabilized undecagold, there are conflicting report
271 on of the 64Cu-labeled triphenylphosphonium (TPP) cations as new radiotracers for imaging tumors by p
274 ethylene glycol) (PEG)-triphenylphosphonium (TPP) polymer (PLGA-b-PEG-TPP) with either nontargeted PL
275 that is decorated with triphenylphosphonium (TPP) cations for detection of mitochondrial membrane pot
276 prepared via complexation with triphosphate (TPP) anions and were successively coated with hyaluronic
279 ionic gelation with sodium tripolyphosphate (TPP), further encapsulated in ZN microparticles, were fo
280 erved heterozygous mutation in KCNJ18 in two TPP patients and two separate heterozygous mutations in
282 1 showed processing activity against various TPP substrates at a level comparable to that of LepB.
284 nide was actually a better catalyst than was TPP in simple solution, where there is a negligible conc
286 +)/RPR(+), 88 were TPP(H)A(+)/RPR(-), 6 were TPP(H)A(-)/RPR(+), and 254 were negative for both tests.
287 ecimens, 241 were TPP(H)A(+)/RPR(+), 88 were TPP(H)A(+)/RPR(-), 6 were TPP(H)A(-)/RPR(+), and 254 wer
291 ) riboswitches, regions of the mRNA to which TPP can bind directly, thus facilitating fine-tuning to
292 multiantigen set performance approached WHO TPP criteria for clinical utility among HIV-uninfected a
295 uptake and tumor/liver ratios, 64Cu(DO2A-xy-TPP)+ is the best candidate for more extensive evaluatio
300 phenylphosphonium Zinpyr-1 diacetate (DA-ZP1-TPP), is essentially nonfluorescent in the metal-free st
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