ライフサイエンスコーパス: TUNEL staining

1 ytochrome C release, caspase 3 activity, and TUNEL staining).

2 alter macrophages bearing a marker of death (TUNEL staining).

3 rase-mediated dUTP-biotin nick end-labeling (TUNEL) staining).

4 tivation, lactate dehydrogenase release, and TUNEL staining.

5 tern blotting, and apoptosis was analyzed by TUNEL staining.

6 for quantification of neovascularization and TUNEL staining.

7 of caspases 3/7, and increased annexin V and TUNEL staining.

8 ivity, reduced cell viability, and increased TUNEL staining.

9 ion, and with minimal caspase activation and TUNEL staining.

10 s and increases in ALT and AST, and positive TUNEL staining.

11 e, despite reduced cell death as measured by TUNEL staining.

12 as indicated by both caspase-3 activity and TUNEL staining.

13 apoptosis was semiquantitatively analyzed by TUNEL staining.

14 Apoptotic cell death was assessed by TUNEL staining.

15 expressing R116C mutant had a high level of TUNEL staining.

16 ndicated by reduced caspase 3 activation and TUNEL staining.

17 72 h that was supported by DNA analysis and TUNEL staining.

18 responded to a similar pattern of silver and TUNEL staining.

19 t LDH leakage, oligonucleosome formation and TUNEL staining.

20 th elevated caspase-3 activity and increased TUNEL staining.

21 ed in tumor tissue in the absence of GLI1 by TUNEL staining.

22 cluding the formation of pyknotic nuclei and TUNEL staining.

23 duced dose-dependent apoptosis with positive TUNEL staining.

24 somic cleavage of DNA (laddering) as well as TUNEL staining.

25 uring retinal developmental as determined by TUNEL staining.

26 orphologic analysis as well as annexin V and TUNEL staining.

27 sions, SMCs and ECs colocalized with IgE and TUNEL staining.

28 se of caspase 8 activation and photoreceptor TUNEL staining.

29 dU incorporation and activated caspase-3 and TUNEL staining.

30 ay, caspase 8 immunoblots, and photoreceptor TUNEL staining.

31 ermined by caspase-3 activation and positive TUNEL staining.

32 Apoptotic cell death was assessed by TUNEL staining.

33 Apoptosis was detected with TUNEL staining.

34 g pathways were assessed by Western blot and TUNEL staining.

35 mmunohistochemistry, immunofluorescence, and TUNEL staining.

36 Apoptotic cell death was assessed by TUNEL staining.

37 ntly increased apoptotic T cells detected by TUNEL staining.

38 rther confirmed by histological analysis and TUNEL staining.

39 leotidyl transferase dUTP nick end labeling (TUNEL) staining.

40 idyl transferase-mediated nick end labeling (TUNEL) staining.

41 rase-mediated dUTP-biotin nick end labeling (TUNEL) staining.

42 idine triphosphate-biotin nick end-labeling (TUNEL) staining].

43 ased after compared with before CPB/CA using TUNEL staining (1.55+/-0.66 versus 0.325+/-0.05%, respec

44 ) at equimolar concentrations as assessed by TUNEL staining [1 mcmol/L: NE (8+/-2%) approximately ISO

45 romodeoxyuridine incorporation and increased TUNEL staining accompanied these decreases.

46 tosis, including no caspase-3 activation, no TUNEL staining, activation of ERKs, and elevated spinal

47 Apoptosis was determined by TUNEL staining, active caspase-3 staining, and by activa

48 From Mason staining and TUNEL staining, aFGF-NP+UTMD group showed significant di

49 transferase-mediated dUTP nick end-labeling (TUNEL) staining after 24 h.

50 inal ganglion cells with fluorescent dye, or TUNEL staining) after up to a 1-year duration of diabete

51 Necrosis and TUNEL staining also increased twofold and sevenfold, res

52 TUNEL staining also revealed less brain apoptosis in tra

53 dUTP nick end labeling (TUNEL) staining also revealed on-going apoptosis specifi

54 TUNEL staining and a nucleosome release assay were used

55 from ischemia-induced apoptosis detected by TUNEL staining and an apoptotic-related DNA fragmentatio

56 Apoptosis was determined by TUNEL staining and annexin-V labeling of phosphatidylser

57 Apoptosis was determined by TUNEL staining and annexin-V labeling of phosphatidylser

58 db/db showed markedly elevated apoptosis by TUNEL staining and caspase 3 levels compared with WT.

59 Apoptosis, as measured by TUNEL staining and caspase expression, was decreased in

60 24 h MCAO was associated with a decrease in TUNEL staining and caspase-3 activity in the control ani

61 inhibition is associated with an increase in TUNEL staining and caspase-3 cleavage and is blocked wit

62 TUNEL staining and caspase-3 cleavage revealed less apop

63 sion in Stat3(DeltaDelta) mice were similar, TUNEL staining and caspase-3 were increased in alveolar

64 ent and there is minimal caspase activation, TUNEL staining and cell death.

65 embryonic day 12.5 (E12.5) according to both TUNEL staining and cleaved caspase 3 immunofluorescence.

66 We show by TUNEL staining and confirm by TEM that apoptosis occurs

67 growth inhibition correlated with increased TUNEL staining and decreased Ki-67 expression in both PC

68 of this mechanism correlates with increased TUNEL staining and decreased ventricular mass and functi

69 Salt-induced PCD (TUNEL staining and DNA laddering) in primary roots of bo

70 Typical apoptotic features (TUNEL staining and DNA laddering) were seen in rat retin

71 Apoptosis was assayed by Hoechst 33258 and TUNEL staining and DNA laddering.

72 Cell death was evaluated with TUNEL staining and ethidium homodimer-1 (EthD) dyes.

73 MRL/+ mice were evaluated for apoptosis with TUNEL staining and Fas and Fas ligand expression with im

74 TUNEL staining and immunostaining for Muller and photore

75 death was observed in the spleen by means of TUNEL staining and in the blood by means of electron mic

76 red staining, was associated with increased TUNEL staining and increased immunopositivity for macrop

77 orn Gsalpha transgenic mice showed increased TUNEL staining and internucleosomal DNA fragmentation co

78 ns, limited segmental demyelination, lack of TUNEL staining and lack of accumulation of ubiquitinated

79 Apoptosis was assessed by TUNEL staining and measuring activity of caspases 3 and

80 Retinal cryosections were examined by TUNEL staining and outer nuclear layer thickness measure

81 Cardiomyocyte apoptosis was determined by TUNEL staining and PARP cleavage (immunoblotting of nucl

82 Interestingly, TUNEL staining and PCNA staining showed neither enhanced

83 TUNEL staining and proteolysis were significantly reduce

84 matolysis, as determined by a combination of TUNEL staining and pulse-field and agarose gel electroph

85 Apoptosis in the RPE was examined by TUNEL staining and quantified by cell-death-detection EL

86 osis, and neuronal cell death, as assayed by TUNEL staining and retinal thickness at 6 and 12 weeks a

87 in articular chondrocytes was identified by TUNEL staining and the immunostaining of cleaved caspase

88 Cell apoptosis was determined by TUNEL staining and the immunostaining of cleaved caspase

89 Brain tissue was subjected to TUNEL staining and TUNEL positive cells were quantified.

90 TUNEL stainings and time-lapse video recordings demonstr

91 erminal transferase d-UTP nick-end labeling (TUNEL) staining and agarose-gel electrophoresis of extra

92 cleotidyltransferase dUTP nick-end labeling (TUNEL) staining and caspase 3 activation.

93 ne 5'-triphosphate-biotin nick end-labeling (TUNEL) staining and DNA gel electrophoresis.

94 rase-mediated dUTP-biotin nick end-labeling (TUNEL) staining and DNA laddering.

95 e death by TdT-dUTP terminal nick-end label (TUNEL) staining and transmission electron microscopy, fo

96 apoptosis (TdT-dUTP terminal nick-end label [TUNEL] staining) and p53 protein expression (immunohisto

97 son Trichrome staining), and apoptosis (with TUNEL staining), and we performed transcriptome analysis

98 otential, Bcl2 to BAX expression, along with TUNEL staining, and Annexin V binding were examined in R

99 hours as shown by nuclear chromatin changes, TUNEL staining, and caspase 3 activation.

100 by histopathology, serum aminotransferases, TUNEL staining, and caspase activation.

101 onstrated by reduced caspase-3 activity, HSC-TUNEL staining, and DNA fragmentation.

102 and apoptosis was assessed by DNA laddering, TUNEL staining, and ELISA for histone-associated DNA fra

103 increased Annexin V-FITC staining, increased TUNEL staining, and increased cleaved caspase 3 protein.

104 Flow cytometry, TUNEL staining, and light microscopy demonstrated that C

105 , as demonstrated by DNA electrophoresis and TUNEL staining, and significantly improved neurological

106 transferase-mediated dUTP nick-end labeling (TUNEL) staining, and blockade by a caspase inhibitor.

107 transferase-mediated dUTP nick end labeling (TUNEL) staining, and DNA laddering.

108 sed for TdT-dUTP terminal nick-end labeling (TUNEL) staining, and the number of nuclei containing fra

109 transferase-mediated dUTP nick end labeling (TUNEL) staining, and Western blot for cleaved caspases.

110 tosis and also determined the reliability of TUNEL staining as an indicator of apoptosis in keratinoc

111 transferase-mediated dUTP nick end labeling (TUNEL) staining as early as 6 hours postlesion.

112 Cell death ELISA and TUNEL staining assays were used to assess apoptosis.

113 Pretreatment with ATA virtually eliminated TUNEL staining at 4 days.

114 asts failed to activate capase-3 or increase TUNEL staining but instead exhibited autophagy, as demon

115 crease in the amount of apoptosis in tips by TUNEL staining, but diminished proliferation throughout

116 rase-mediated dUTP-biotin nick end labeling (TUNEL) staining, but not in neurons.

117 umber of apoptotic myocytes as determined by TUNEL staining by 3.6- fold.

118 e results demonstrate that the diminution in TUNEL staining by alpha-MSH is through alpha-MSH mediati

119 ite-bearing neurons against the induction of TUNEL staining by high glucose.

120 n and a decrease in apoptosis as measured by TUNEL staining, caspase 3 activation, and DNA laddering

121 mediated dUTP-digoxigenin nick-end labeling (TUNEL) staining, caspase-3 activation, and myeloperoxida

122 The IEC TUNEL staining, caspases 3, 8, and 9, and p53 protein le

123 rase-mediated dUTP-biotin nick end labeling (TUNEL) staining characteristic of apoptosis.

124 c cell death at a high frequency as shown by TUNEL staining, chromatin condensation, and the appearan

125 leotidyl transferase dUTP nick-end labeling (TUNEL) staining, circulating levels of alanine aminotran

126 0.25 mM H(2)O(2) for 1 hour showed increased TUNEL staining compared with nonstressed cells (17 +/- 1

127 nd incorporated more 5-bromodeoxyuridine and TUNEL staining compared with unstimulated controls.

128 MDA (P = 0.006), but not M30 CK18 levels or TUNEL staining, compared to subjects without stainable h

129 TUNEL staining confirmed that photoreceptor and bipolar

130 DNA fragmentation detected by TUNEL staining could be induced by staurosporine and Fas

131 TUNEL staining coupled with morphologic assessment was p

132 The number of apoptotic cells using TUNEL staining decreased by nearly 50% in NGF-cultured i

133 TUNEL staining demonstrated increased rates of apoptosis

134 ear-infrared imaging of caspase activity and TUNEL staining demonstrated that TRA-8 rapidly induced a

135 TUNEL staining demonstrated the presence of apoptotic ce

136 transferase-mediated dUTP nick end labeling (TUNEL) staining demonstrated a 4-fold increase in apopto

137 ng flow cytometric analysis of PI uptake and TUNEL staining, DNA electrophoresis, and electron micros

138 independent measures of apoptosis, including TUNEL staining, DNA laddering, and caspase-3 activity, a

139 transferase-mediated dUTP nick end labeling (TUNEL) staining, DNA fragmentation, caspase-3 activity,

140 TUNEL staining for apoptosis was performed on 8 paraform

141 detected by increased BrdU labeling, whereas TUNEL staining for apoptotic cells was unaffected.

142 TUNEL staining for DNA double-strand breaks confirmed th

143 sessed by both Cresyl violet staining and by TUNEL staining for DNA fragmentation.

144 transferase-mediated dUTP nick-end labeling (TUNEL) staining for intratumoral apoptosis.

145 mediated dUTP-digoxigenin nick end-labeling (TUNEL) staining, glial fibrillary acidic protein (GFAP)

146 TUNEL staining identified dying cells at P14 through P60

147 DNA fragmentation was evident on TUNEL staining in 10/15 subjects injected with hemolysat

148 pho-Akt (P-Akt) staining accompanied by weak TUNEL staining in Axl-positive tumors, suggesting an ant

149 Extensive cell death was also detected by TUNEL staining in focal areas around lesions.

150 Retinal thinning, TUNEL staining in ONL, 4-HNE-, and 4-HHE protein modific

151 We also observed DNA cleavage determined by TUNEL staining in TBBEC treated with LPS.

152 l ischemic lesion area and largely prevented TUNEL staining in the cortex.

153 TUNEL staining in the MPNc was very low and although it

154 nd a statistically significant difference in TUNEL staining in tumor tissue between mice treated with

155 leotidyl transferase dUTP nick end labeling (TUNEL) staining in situ.

156 idine triphosphate-biotin nick-end labeling (TUNEL) staining in tumor biopsies (n = 15).

157 leotidyl transferase dUTP nick-end labeling (TUNEL) staining in vascular cells within the neovascular

158 (i.p.) of METH (30 mg/kg) induces apoptosis (TUNEL staining) in approximately 25% of neurons in the s

159 optosis (decreased cell viability, increased TUNEL staining, increased expression of cleaved PARP, cl

160 Positive TUNEL staining, increases in caspase-2 and -3 cleavage,

161 TUNEL staining indicated that PS-341 treatment sensitize

162 cytes showed more cleaved caspase-3 and more TUNEL staining, indicating an anti-apoptotic function of

163 d insulin+ beta-cells with some positive for TUNEL staining, indicating apoptosis.

164 ximately 20% of satellite cells positive for TUNEL staining, indicating DNA damage associated with ap

165 rase-mediated dUTP-biotin nick end labeling (TUNEL) staining, indicating that the gene 7 products do

166 Cerebellar granule cells demonstrated high TUNEL staining indicative of apoptosis.

167 mal cornified layers and increased epidermal TUNEL staining, indicative of premature keratinocyte pro

168 Total lung lavage protein concentration, TUNEL staining, lipid peroxidation, and wet-to-dry ratio

169 ages and granulocytes that were apoptotic by TUNEL staining occasionally appeared to display A1 throu

170 Maximal TUNEL staining occurred in the piriform cortex between 1

171 Intense TUNEL staining of apoptotic cells was seen earlier (1 da

172 ogradely labeled neurons and no evidence for TUNEL staining of axotomized cortical motoneurons.

173 inding and time course of apoptosis, whereas TUNEL staining of cardiac tissue sections identified spo

174 TUNEL staining of CNS tissue demonstrates the presence o

175 TUNEL staining of infected lung sections demonstrated in

176 S of P2X7R-/- mice early in the disease, and TUNEL staining of inflamed CNS tissues supported this re

177 TUNEL staining of lens epithelial cells in capsulotomy s

178 Blood levels of caspase 3 and TUNEL staining of liver were also reduced in dexamethaso

179 TUNEL staining of senescent HSCs showed approximately 21

180 TUNEL staining of the inner retina of the mouse was most

181 enzymatic assay of myocardial caspase 3 and TUNEL staining of tissue sections.

182 lls in the lamina propria and spleen by both TUNEL staining of tissues and dispersed spleen cell popu

183 cleotidyl transferase UTP nick-end labeling (TUNEL) staining of histologic sections in wild-type and

184 rase-mediated dUTP-biotin nick end labeling (TUNEL) staining of intestinal sections revealed increase

185 transferase-mediated dUTP nick end-labeling (TUNEL) staining of lymphoid tissues (pharyngeal tonsil,

186 Apoptosis was assayed by TUNEL staining on preparations of corneal tissue section

187 ckness in paraffin-embedded sections, and by TUNEL staining on retinal cryosections.

188 ring ischemia alone, but it colocalized with TUNEL staining over the 3 time points of reperfusion.

189 tohepatitis (P < 0.05) and increased hepatic TUNEL staining (P = 0.02), as well as increased serum le

190 TUNEL staining peaked at 12 h, earlier than the diminish

191 TUNEL staining, real-time RT-PCR, immunostaining, and EL

192 TUNEL staining, real-time RT-PCR, polymorphonuclear neut

193 nsferase mediated dUTP nick end labeling, or TUNEL, staining, respectively, and were compared with cl

194 TUNEL staining results corroborated this finding.

195 TUNEL-staining results in cultured stromal cells (kerato

196 Lineage tracing and TUNEL staining reveal that Nanos1-deficient PGCs fail to

197 TUNEL staining revealed a 6-fold increase in the number

198 Neither the DNA laddering assay nor TUNEL staining revealed an increase in apoptosis of PKCd

199 TUNEL staining revealed more apoptotic hypertrophic chon

200 Our data suggest that TUNEL staining should be evaluated with morphological ch

201 Moreover, TUNEL staining showed a high percentage of apoptotic cho

202 TUNEL staining showed cell death only around bubbles and

203 TUNEL staining showed little DNA breakage in neutrophils

204 TUNEL staining showed reduced apoptosis in the thymus of

205 TUNEL staining showed that ghrelin mitigated the signifi

206 TUNEL staining showed that the percent TUNEL positive nu

207 TdT-mediated nick end-label (TUNEL) staining showed apoptotic cells in regions expres

208 transferase-mediated dUTP nick end-labeling (TUNEL) staining suggested that cell death was due to apo

209 e in the rate of apoptosis, as determined by TUNEL staining, suggesting it plays a non-apoptotic role

210 ot result in detectable DNA strand breaks by TUNEL staining that are hallmarks of the classical apopt

211 TUNEL staining to detect apoptosis and immunohistochemic

212 resent study using propidium iodide and FITC-TUNEL staining to identify apoptotic cells, demonstrates

213 a high permeability to Ca(2+), we performed TUNEL staining to investigate the effects of receptor up

214 Instead, TUNEL staining, together with Fas, active caspase-3, and

215 Early in reperfusion, TUNEL staining was colocalized with endothelial cells fr

216 TUNEL staining was diminished after intravitreal TNF-alp

217 TUNEL staining was increased in Cx50D47A lenses, especia

218 TUNEL staining was marked, but ssDNA and cleaved caspase

219 cell death of transplanted RPE, as judged by TUNEL staining was observed rarely.

220 he corneas were processed for histology, and TUNEL staining was performed to assess whether blue-IRIS

221 TUNEL staining was performed to assess whether IRIS or N

222 TUNEL staining was performed to detect apoptosis.

223 Intense TUNEL staining was seen in BALB/c versus B6 cornea at 1

224 TUNEL staining was used for identification of apoptotic

225 TUNEL staining was used to analyze the cytotoxicity of T

226 ative stress was localized using 8-OHdG, and TUNEL staining was used to detect apoptosis.

227 TUNEL staining was used to quantitate the number of cell

228 TUNEL staining was variable.

229 idyl transferase-mediated nick-end labeling (TUNEL) staining was minimal in mice fed either diet befo

230 leotidyl transferase dUTP nick-end labeling (TUNEL) staining was performed to quantify apoptotic cell

231 TUNEL-staining was positive in the outer nuclear layer o

232 aspase 3 enzymatic activity and apoptosis by TUNEL staining were also increased after 12 weeks of dox

233 Immunoreactive p21/WAF1 and TUNEL staining were used as indicators of p53 activity f

234 Caspase-3 activity and TUNEL-staining were increased in KD hearts after ischemi

235 within 24 h and many cells were apoptotic by TUNEL staining, whereas virulent H37Rv exhibited minimal

236 enced by elevated caspase-3, -9 activity and TUNEL staining, which was completely blocked by Ucf-101,

237 rase-mediated dUTP-biotin nick end labeling (TUNEL) staining with GFP.

238 TUNEL staining (with or without PMN depletion) and PMN i

239 There was TUNEL staining within choroidal neovascular lesions in e