ライフサイエンスコーパス: Tat protein

1 h transactivation of the HIV promoter by the Tat protein.

2 a cell-penetrating peptide derived from the TAT protein.

3 es capable of neutralizing the effect of the Tat protein.

4 those observed for peptides derived from the Tat protein.

5 human immunodeficiency virus type I (HIV-1) Tat protein.

6 oter of HIV-1 that is activated by the HIV-1 Tat protein.

7 n sequence from human immunodeficiency virus TAT protein.

8 similar to those of the ungulate lentiviral Tat protein.

9 s for deleterious mutations elsewhere in the Tat protein.

10 PTD) derived from the human immunodeficiency TAT protein.

11 erase II is strongly stimulated by the viral Tat protein.

12 onal repression by DRB and activation by the Tat protein.

13 human immunodeficiency virus type 1 (HIV-1) Tat protein.

14 n elongation complexes is inhibited by HIV-1 Tat protein.

15 ed cells were treated with exogenously added Tat protein.

16 n in the presence of either DRB or the HIV-1 Tat protein.

17 Vpu also expressed a functional single-exon Tat protein.

18 fection with HIV-1, in part due to the HIV-1 Tat protein.

19 physical interaction between MED14 and HIV-1 Tat protein.

20 annels in the response of microglia to HIV-1 Tat protein.

21 least 1000-fold more toxic than recombinant Tat protein.

22 orescence microscopy of Texas Red-conjugated TAT proteins.

23 for transcriptional activation by lentivirus Tat proteins.

24 o the translocon, FRET was observed for both Tat proteins.

25 g the HIV-1 transactivator of transcription (Tat) protein.

26 e and HIV-1 transactivator of transcription (Tat) protein.

27 dies examined the ability of two variants of Tat protein (1-100 nM), Tat 1-72 and Tat 1-86, to produc

28 Treatment of rat microglia with HIV-1 Tat protein (200 ng/ml) resulted in pro-inflammatory mic

29 s cellular defense, HIV-1 has evolved in its Tat protein a suppressor of RNA silencing (SRS) function

30 he human immunodeficiency virus type 1 (HIV) Tat protein, a potent activator of HIV gene expression,

31 Here we demonstrate that HIV-1 Tat protein, a potent viral transactivator shown to be r

32 l region of the human immunodeficiency virus Tat protein, a protein transduction domain known to ente

33 demonstrate that highly divergent lentiviral Tat proteins activate transcription from their cognate L

34 Treatment with HIV-tat protein activated NF-kappa B, degraded I kappa B alp

35 wnstream of the MyD88 and TRIF pathways, the Tat protein activated the protein kinase C (PKC) betaII

36 As the HIV-1 Tat protein activates the overall expression of the huma

37 Human immunodeficiency virus, type 1 (HIV-1) Tat protein activates transcription from the HIV-1 long

38 s basal HIV gene expression and that the HIV Tat protein activates transcription independently of the

39 uman immunodeficiency virus, type 1 (HIV-1), Tat protein activates viral gene expression through prom

40 T-tg or C57BL/6J mice; however, induction of Tat protein after the extinction of CPP also produced re

41 by vGPCR was greatly increased by the HIV-1 Tat protein, although Tat alone had little effect on NF-

42 ransduction domain (PTD) embedded in the HIV TAT protein (amino acids 47-57) has been shown to succes

43 study was to determine whether and how HIV-1 Tat protein, an immunosuppressive viral factor, induces

44 PI3K-dependent inhibition required the viral Tat protein and a trans activation response region eleme

45 ar cofactor cyclin T1, which binds the viral Tat protein and activates the RNA polymerase II transcri

46 We found HIV-Tat protein and IL-17-expressing mononuclear cells in th

47 ble to that of the RNA-binding domain of the Tat protein and inhibited protein binding to the RNA.

48 uction of NO production by recombinant HIV-1 Tat protein and inhibition of RSV-tat-induced NO product

49 anges conformation in response to binding of Tat protein and of a variety of peptidic and small molec

50 e suggest a model where CycT1 interacts with Tat protein and positions the protein complex to make co

51 The HIV-1 Tat protein and several small molecules bind to HIV-1 tr

52 M) of the human immunodeficiency virus (HIV) Tat protein and TAR RNA is essential for Tat activation

53 Novel systems using Tat protein and the GHOST cell line were developed to te

54 mation of a specific complex between the HIV Tat protein and the small RNA element TAR is critical fo

55 cture, termed TAR RNA, in concert with HIV-1 Tat protein and these positive and negative elongation f

56 protein transduction domain (PTD) of the HIV/TAT protein and transduced pancreatic islets ex vivo wit

57 ciates with the human immunodeficiency virus Tat protein and with the transactivation response elemen

58 man immunodeficiency virus 1-transactivator (Tat) protein and linked to the mitochondrial targeting s

59 V replication, with associated production of Tat protein, and C. parvum infection synergistically inc

60 with the human immunodeficiency virus type 1 Tat protein, and Drosophila mof, a gene essential for ma

61 s have documented the neurotoxic property of Tat protein, and Tat has therefore been proposed to cont

62 observed that neuronal cultures treated with Tat protein are protected from Tat-mediated cytotoxicity

63 ysiology of M. smegmatis and homologs of the TAT proteins are also present in the genome of Mycobacte

64 and simian immunodeficiency virus (HIV/SIV) Tat proteins are specified by two coding exons.

65 Our results demonstrate that Tat protein associates with RNA polymerase II complexes

66 ptide mimic of the RNA-binding domain of BIV Tat protein based on a designed beta-hairpin scaffold.

67 d, however, by immunization with inactivated Tat protein before vaccination with the bicistronic gp12

68 tides from the carboxy terminus of the HIV-1 Tat protein bind to the apical stem-loop region of TAR R

69 The arginine-rich RNA-binding domains of the Tat proteins bind to their cognate transactivation respo

70 At the HIV-1 promoter, the viral Tat protein binds simultaneously to the nascent TAR RNA

71 Our previous studies showed that HIV-1 Tat protein binds to PP1 through the Tat Q(35)VCF(38) se

72 The bovine immunodeficiency virus (BIV) Tat protein binds with high affinity to its TAR RNA site

73 This minimal hybrid mutant hCycT1-Tat protein bound TAR RNA as well as human and murine P-

74 NF-kappa B, AP-1, JNK, and apoptosis by HIV-tat protein but has minimal or no role in activation of

75 h protein-protein interaction with the HIV-1 Tat protein can also activate cad transcription.

76 The HIV Tat protein can be endocytosed by surrounding uninfected

77 Here we show that HIV-1 Tat protein can directly promote KSHV transmission.

78 In cultured cells, the HIV-1 Tat protein can induce the expression of the cytokines i

79 ch as HIV-1 Transactivator of Transcription (Tat) protein can activate microglia is thus of paramount

80 Specific HIV proteins, such as Tat protein, can contribute to the dysfunction of tight

81 Administration of recombinant HIV-1 Tat protein caused a 13-fold increase in HERV-K (HML-2)

82 histiocytic lymphoma U937 cells with the HIV-tat protein causes activation of JNK and AP-1 in a time-

83 piCCT1 has a region of similarity to the HIV Tat protein cell-transduction domain, we tested whether

84 RNA polymerase II, is regulated by the HIV-1 Tat protein, CK2, TFIIB, and the large subunit of TFIIF

85 in vitro biochemical assays with recombinant Tat protein confirmed that TR1 targets two disulfide bon

86 The recombinant HIV-1 Tat protein contains a small region corresponding to res

87 cause HIV-1 Transactivator of Transcription (Tat) protein continues to be present despite antiretrovi

88 The HIV-1-encoded Tat protein controls transcription elongation by increas

89 The Tat protein controls transcription in lentiviruses such

90 We discovered that HIV-Tat protein could be transported along anatomical pathwa

91 Hence we examined if Tat protein could directly activate T cells.

92 Using an HIV-1 Tat protein-derived peptide to mediate rapid and efficie

93 exposure of cultures to a deletion mutant of Tat protein devoid of amino acids 31-61 (Tat Delta31-61)

94 The human immunodeficiency virus Tat protein directly associates with CycT1 to utilize Cy

95 Moreover, the CycT1 complex formed by each Tat protein displays a distinct RNA target specificity t

96 pendent on the same cellular cofactor as the Tat proteins encoded by other lentiviruses, is neverthel

97 Tat protein, encoded by one of the HIV-1 regulatory gene

98 ne composition in the proper function of the Tat protein export pathway.

99 uorum-sensing and uncover a function for the Tat protein export system in the production of secreted

100 The Tat protein export system translocates folded proteins a

101 TAT peptides derived from the HIV-1 TAT protein facilitate intracellular delivery of protein

102 ly proposed a two-step model where the viral Tat protein first preassembles at the promoter with an i

103 The pretreatment of human monocytes with Tat protein for 10 to 30 min suffices to irreversibly en

104 d to the nontoxic transduction domain of the tat protein from human immunodeficiency virus type 1 (ta

105 recently identified inhibitors of the viral Tat protein from the bovine immunodeficiency virus (BIV)

106 In this study, we demonstrate that Tat proteins from representative HIV-1 subtype E isolate

107 ates transactivation by Tat and suggest that Tat proteins function by localizing such a PITALRE-conta

108 Brief exposure (10 min) to each variant of Tat protein (>1 nM) markedly increased levels of intrace

109 athione peroxidase, NK-lysin/granulysin, HIV Tat protein, H(2)O(2), lipid hydroperoxides, vitamin K,

110 The human immunodeficiency virus (HIV) Tat protein has a critical role in viral transcription,

111 The human immunodeficiency virus (HIV)-Tat protein has been implicated in the neuropathogenesis

112 The HIV-1 Tat protein has been reported to exert an adverse effect

113 human immunodeficiency virus type 1 (HIV-1) Tat protein has been reported to transactivate several c

114 ddition, our results indicate that the alpha-TAT protein has functions that require acetyltransferase

115 findings are particularly important because Tat protein has recently been detected in the brain of H

116 ated that a TAT peptide derived from the HIV TAT protein has the ability to transduce peptides or pro

117 Several HIV-1-derived proteins including the Tat protein have been shown to transcriptionally repress

118 In marked contrast, bovine lentiviral Tat proteins have evolved a high-affinity TAR interactio

119 The virally encoded Tat protein hijacks positive transcription elongation fa

120 human immunodeficiency virus type 1 (HIV-1) Tat protein (hTat) activates transcription initiated at

121 Here the specific interaction between Tat protein, human cyclin T1, and HIV-1 TAR RNA was anal

122 Here we report that synthetic HIV-1 Tat protein, immobilized on a solid substrate, up-regula

123 ndent on the presence of both HAT domain and Tat proteins, implying that Tat influences the transcrip

124 ese effects, we constitutively expressed HIV-Tat protein in astrocytes.

125 Recently, we showed the presence of Tat protein in brains of patients with HIV-1 encephaliti

126 an elongation block that is overcome by HIV Tat protein in conjunction with P-TEFb.

127 gain a better understanding of the roles of Tat protein in HIV-1 neuropathogenesis, we attempted to

128 whole organism to support a critical role of Tat protein in HIV-1 neuropathogenesis.

129 nly further highlights the importance of HIV Tat protein in HIV/neuroAIDS, but also presents a new st

130 wn to suppress transcriptional activation by Tat protein in human cells with an IC(50) of approximate

131 n the activation of transcription by the HIV Tat protein in human cells.

132 ctivation, we explored the role of the HIV-1 Tat protein in inducing the expression of these endogeno

133 Inclusion of recombinant Tat protein in the boosting phase along with the Env pro

134 nterferes with transcriptional activation by Tat protein in vitro and in HeLa cells.

135 R is not required for binding by recombinant Tat protein in vitro, suggesting that the loop region ac

136 L response to autologous virus Env, Gag, and Tat proteins in three patients, and investigated the ext

137 We show here that HIV type 1 (HIV-1) Tat protein, in combination with anti-CD3/CD28 mAbs, pro

138 mbinant biologically active HIV-1-associated Tat protein increased FasL expression in the cytoplasm o

139 cryptosporidiosis, we found that recombinant Tat protein increased TLR4 mRNA expression in both uninf

140 HIV-1 Tat protein increases synaptic dopamine (DA) levels by d

141 itioned media from astrocytes or recombinant Tat protein inhibited NPC proliferation and migration an

142 In this study, we show that the HIV-1 Tat protein interacts with rapid kinetics to engage the

143 in the brain, or by injection of recombinant Tat protein into the brain, which may cause secondary st

144 human immunodeficiency virus type 1 (HIV-1) Tat protein is a key pathogenic factor in a variety of a

145 The HIV-1 Tat protein is a potent neurotoxin produced during HAND

146 eptide from the Jembrana disease virus (JDV) Tat protein is a structural "chameleon" that binds bovin

147 efore, this study analyzed whether the HIV-1 Tat protein is able to activate these two pathways separ

148 g domain of the Jembrana disease virus (JDV) Tat protein is able to recognize two different TAR RNA s

149 As Tat protein is actively released by HIV-1 infected cells

150 l repeat (LTR) promoter element by the viral Tat protein is an essential step in the HIV-1 life cycle

151 Human immunodeficiency virus (HIV)-1 Tat protein is an important pathogenic factor in HIV-ass

152 The Tat protein is essential for HIV type 1 (HIV-1) replicat

153 human immunodeficiency virus type 1 (HIV-1) Tat protein is essential for viral replication and stimu

154 The human immunodeficiency virus Tat protein is essential for virus replication and is a

155 that the bovine immunodeficiency virus (BIV) Tat protein is fully able to bind to BIV TAR both in viv

156 mmunodeficiency virus (HIV) infection, HIV-1 Tat protein is known to synergize with psychostimulant d

157 protein Puralpha and the HIV type 1 (HIV-1) Tat protein is mediated by specific ribonucleic acids.

158 deregulation of neuronal functions by HIV-1 Tat protein is miRNA-dependent.

159 The HIV-1 Tat protein is one of the proteins present in HIV that a

160 n of the bovine immunodeficiency virus (BIV) Tat protein is shown to bind specifically to its target

161 We report here that the HIV Tat protein is strongly immunosuppressive, both immediat

162 The HIV-1 Tat protein is translated from the early spliced mRNA an

163 The transactivator of transcription (Tat) protein is essential for efficient HIV type 1 (HIV-

164 we showed that neurotoxic factors other than Tat protein itself were present in the supernatant of Ta

165 in a Jurkat cell line stably expressing the Tat protein (Jurkat-Tat) or in Jurkat cells treated with

166 nd, unlike human papillomavirus E6 and HIV-1 TAT proteins, LANA did not reduce TIP60 stability.

167 Since the nuclear presence of Tat protein leads to alteration of host gene expression,

168 ion with HIV-1 or stimulation with the HIV-1 Tat protein leads to the activation of K111 proviruses.

169 TLR4 pathway with rapid kinetics, the HIV-1 Tat protein leads to the engagement of both the MyD88 an

170 TLR4 pathway with rapid kinetics, the HIV-1 Tat protein leads to the engagement of both the MyD88 an

171 HIV-tat protein, like TNF, activates a wide variety of cellu

172 Human immunodeficiency virus-1 tat (HIV-tat) protein, like other proinflammatory cytokines (such

173 hat the HIV transactivator of transcription (Tat) protein manipulates the intrinsic toggling of HIV's

174 These data indicate that the HIV-1 Tat protein may act as a protocytokine by causing the re

175 Hence, Tat protein may induce autophagosome and lysosome fusion

176 y virus type 1 (HIV-1) potent transactivator Tat protein mediates pleiotropic effects on various cell

177 To characterize the mechanism by which HIV-1 Tat protein modulates human brain microvascular endothel

178 ned whether exposure of susceptible cells to Tat protein of HIV could result in the production of sel

179 The Tat protein of human immunodeficiency virus (HIV) is ess

180 The Tat protein of human immunodeficiency virus type 1 (HIV-

181 The Tat protein of immunodeficiency viruses is the main acti

182 ation to define the interactions between the Tat proteins of Escherichia coli at molecular-level reso

183 Asparagine is prevalent in Tat proteins of viruses in clades A, C, and D, which are

184 Here we investigated the effects of the Tat protein on enteric neuronal excitability, proinflamm

185 the KS-promoting factor TNF-alpha, the HIV-1 Tat protein, or the human herpesvirus 8 protein ORF74, w

186 The transacting activator of transduction (TAT) protein plays a key role in the progression of AIDS

187 e 1 (HIV-1) transactivator of transcription (Tat) protein possesses a unique membrane-transduction pr

188 f Tat and respond similarly to extracellular Tat protein produced during infection.

189 ady-state RNA levels, and with intracellular Tat protein production, suggesting that antisense transc

190 nding to the same site as arginine 52 of the Tat protein, rather than to the neomycin binding site.

191 The viral Tat protein recruits human Super Elongation Complex (SEC

192 The viral Tat protein recruits human super elongation complexes (S

193 human immunodeficiency virus type 1 (HIV-1) Tat protein recruits positive transcription elongation f

194 human immunodeficiency virus type-1 (HIV-1) Tat protein regulates transcription by stimulating RNA p

195 HIV-1 Tat protein regulates transcription elongation by bindin

196 The HIV-1 Tat protein regulates transcription elongation through b

197 Tat protein released from HIV-infected blood-borne leuko

198 ed with a variant TAR able to bind all three Tat proteins replicate efficiently with any of the prote

199 LTR) promoter element by the essential viral Tat protein requires recruitment of positive transcripti

200 demonstrated that exposure of HUVECs to HIV Tat protein resulted in induced expression of cell adhes

201 domain from the human immunodeficiency virus TAT protein, results in delivery of the biologically act

202 position 31, found in >90% of HIV-1 clade C Tat proteins, results in a marked decrease in IL-10 prod

203 Analysis of different Tat proteins revealed that the 101-amino-acid SF2 HIV-1

204 component of the twin-arginine translocase (Tat) protein secretion pathway and likely forms a secret

205 The HIV-1 Tat protein selectively recruits P-TEFb as part of a sup

206 found that treatment of DCs with whole HIV-1 Tat protein significantly upregulated the level of expre

207 Our results also show that HIV-1 Tat protein stimulated DSIF and RNA pol II phosphorylati

208 ealthy or HIV-1-infected patients with HIV-1 Tat protein stimulated the expression of PD-L1.

209 The HIV type 1 (HIV-1) Tat protein stimulates transcription elongation by recru

210 The HIV-1 Tat protein stimulates viral gene expression by recruiti

211 Tat protein strongly activates transcription from the hu

212 FP-SsrA or upon overexpression of the native Tat proteins SufI and CueO.

213 cein-labeled TAR RNA and a rhodamine-labeled Tat protein synthesized through solid-phase chemistry.

214 uction was achievable, as minimum amounts of Tat protein, synthesized following application of a shor

215 n domain of the human immunodeficiency virus TAT protein (Tat), an Angiopep peptide (Ang-2), and the

216 Here, we report that ACs treated with HIV-1 Tat protein (Tat-ACs) have a decreased ability to organi

217 ll membrane transduction domain of the HIV-1 Tat protein (TAT-C24WT).

218 treatment with a CRMP2 peptide fused to HIV TAT protein (TAT-CBD3) blocked neuronal death following

219 udy the interaction between PTD of the HIV-1 Tat protein (TAT-PTD; residues 47-60 of Tat, fluorescent

220 g domain of the human immunodeficiency virus Tat protein (Tat-srIkappaBalpha).

221 to the HIV transactivator of transcription (TAT) protein (TAT-CBD3) decreased neuropeptide release f

222 ed to the protein transduction domain of HIV-TAT protein (TATFLAGVHL-peptide) to facilitate entry int

223 An 11-residue basic domain of the HIV-1 tat protein, termed the tat transduction domain (TTD), h

224 element is regulated by the essential viral Tat protein that binds to the viral TAR RNA target and r

225 netrating peptide (CPP) conjugate of the HIV TAT protein that is fused to an aminoterminal sequence o

226 immunodeficiency virus (SIVmnd), also encode Tat proteins that activate transcription via RNA targets

227 ty is seen in viral replication assays using Tat proteins that rely on CycT1 for TAR binding but are

228 upporting HIV-1 transactivation by the viral Tat protein, the AFF4-SEC is more important for HSP70 in

229 ed by the human immunodeficiency virus (HIV) Tat protein to activate elongation of the integrated pro

230 tion complex (SEC) used by the viral encoded Tat protein to activate HIV transcription.

231 mbrana disease virus (JDV) utilize the viral Tat protein to activate viral transcription.

232 These studies link the HIV-1 Tat protein to cell cycle-specific biological functions.

233 in concert with these factors and the HIV-1 Tat protein to ensure that viral transcription is induce

234 fused to the polybasic sequence from the HIV Tat protein to facilitate entry into cells.

235 conjugation of peptides derived from the HIV TAT protein to membrane-impermeant molecules has gained

236 protein, called the TAT peptide, enables the TAT protein to penetrate cell membranes.

237 Binding of the HIV tat protein to the TAR (transactivating response region)

238 continues to synergize normally with the HIV Tat protein to transactivate the HIV long terminal repea

239 at is responsible for the inability of these Tat proteins to produce high IL-10 levels in monocytes d

240 report that binding of HIV-1 transactivator (Tat) protein to low-density lipoprotein receptor-related

241 and is the site of interaction of the HIV-1 Tat protein together with host cellular factors.

242 th versions of these peptides containing HIV-Tat protein transduction and mammalian mitochondrial tar

243 The TAT protein transduction domain (PTD) has been used to d

244 or-associated Ag (OVA) that contains the HIV TAT protein transduction domain (PTD) was readily engine

245 r uptake of the human immunodeficiency virus TAT protein transduction domain (PTD), or cell-penetrati

246 ass IA PI3K adaptor subunit, fused to an HIV-TAT protein transduction domain (TAT-Deltap85) concentra

247 nto mice of dnRas, which was fused to an HIV-TAT protein transduction domain (TAT-dnRas).

248 When fused to the HIV-TAT protein transduction domain and delivered as a prote

249 d recombinant fusion proteins containing the TAT protein transduction domain and either wild-type Sur

250 ptide was redesigned to TSB2 that includes a TAT protein transduction domain and shortened to 14 aa.

251 een fluorescent protein or dnRas lacking the TAT protein transduction domain did not block airway inf

252 esults provide insight into the mechanism of TAT protein transduction domain transduction.

253 is fused to the human immunodeficiency virus TAT protein transduction domain.

254 directed mutagenesis and fused downstream of TAT protein transduction domain.

255 tor, p16INK4a that contained an NH2-terminal TAT protein transduction domain.

256 a physiological role for nuclear RACK1, the Tat protein transduction system was used to transduce RA

257 The transactivator of transcription (TAT) protein transduction domain is an 11-amino acid pos

258 we used the transactivator of transcription (TAT) protein transduction domain to deliver human FXN pr

259 e effect of transactivator of transcription (TAT) protein transduction of the apoptosis repressor wit

260 The twin-arginine (Tat) protein translocase is a highly unusual protein tra

261 Current models for Tat protein transport are also discussed.

262 drical structures that may correspond to the Tat protein transport channel.

263 omponents of the thylakoid deltapH-dependent/Tat protein transport machinery was analyzed in vitro.

264 te the mechanism and energetics of bacterial Tat protein transport, we developed an efficient in vitr

265 protein (GFP)-tagged constructs to study the Tat protein transporter and Rieske Tat substrates in Syn

266 ormation of TAR RNA and its interaction with Tat protein under physiological conditions.

267 Our results demonstrate that HIV-1 Tat protein upregulates PD-L1 expression on MoDCs throug

268 ophobic domain may play an important role in Tat protein uptake and be useful for intracellular deliv

269 The viral Tat protein utilizes Cyclin T1 to activate proviral tran

270 HIV-1-derived TAT protein variants contain a transmembrane domain, whi

271 By detection of the Tat protein, virus transmission can be detected in high-

272 The visna virus Tat protein was also able to interact with covalently cr

273 Here, we demonstrate that the Cv-pdg-NLS-TAT protein was delivered to repair-proficient keratinoc

274 The colored Tat proteins were easily visible during purification, en

275 n domain of the human immunodeficiency virus TAT protein, were tested in in vitro and in vivo experim

276 ion of human immunodeficiency virus requires Tat protein which activates elongation of RNA polymerase

277 Replication of HIV-1 requires the Tat protein, which activates elongation of RNA polymeras

278 Replication of HIV requires the Tat protein, which activates elongation of RNA polymeras

279 opolysaccharide (LPS) and the neurotoxic HIV Tat protein, which cause dopamine neuronal toxicity afte

280 utlined various strategies for detecting the Tat protein, which helps transcribe the virus and enhanc

281 Replication of HIV-1 requires the viral Tat protein, which increases the extent of transcription

282 cy virus (HIV)-1 genes is activated by HIV-1 Tat protein, which induces phosphorylation of the C-term

283 This is mediated in part through the HIV-1 Tat protein, which is secreted by the infected cells and

284 by the human immunodeficiency virus, type 1 Tat protein, which is secreted by virally infected cells

285 Here, we report that the HIV-1 Tat protein, which is secreted from virus-infected cells

286 HIV Tat protein, which is the transactivator of transcriptio

287 ide (Abeta1-6A2V), linked to the HIV-related TAT protein, which is widely used for brain delivery and

288 HIV-infected macrophages release Tat protein, which may act directly on neurons to cause

289 HIV-1 transcription is activated by HIV-1 Tat protein, which recruits cyclin-dependent kinase 9 (C

290 V-1) transcription is regulated by the viral Tat protein, which relieves a block to elongation by rec

291 human immunodeficiency virus type 1 (HIV-1) Tat protein, which was able to restore the 7SK-binding a

292 V-1) replication requires the interaction of Tat protein with the human cyclinT1 (hCyclinT1) subunit

293 1 (HIV-1) requires specific interactions of Tat protein with the trans -activation responsive region

294 1 (HIV-1) requires specific interactions of Tat protein with the trans-activation responsive region

295 expression that requires the interaction of Tat protein with the trans-activation responsive region

296 expression that requires the interaction of Tat protein with the trans-activation responsive region

297 1 (HIV-1) requires specific interactions of Tat protein with the trans-activation responsive region

298 ciency virus (HIV) tat and boosting with the Tat protein would elicit protection against SHIV(89.6P).

299 to membrane translocation signals from HIV-1 tat protein (YGRKKRRQRRRPP-LRK(5)H, DT-2) or Drosophila

300 Vector constructs lacking a functional Tat protein yielded titers of around 4 x 10(6) to 8 x 10