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1 he expression of the innate immune receptor, Toll-like receptor 3.
2 ary and sufficient to stimulate WIHN through toll-like receptor 3.
3 nents to endosomal compartments that contain Toll-like receptor-3.
4 ch no signaling occurs via the intracellular Toll-like receptors 3, 7 and 9 (sensors for double-stran
5 RNA expression of protein kinase R (PKR) and Toll-like receptors 3, 7, and 9 was also measured from c
6  responses to RSV that correlated with lower Toll-like receptor 3/7 transcript and decreased expressi
7                                              Toll-like receptor 3-activated macrophages confer anti-H
8                Prestimulation of MSCs with a toll-like receptor 3 agonist further enhanced the therap
9                                 We show that toll-like receptor 3 agonist Poly I:C, combined with exo
10 ted, polyinosinic:polycytidylic acid (PIC, a Toll-like receptor 3 agonist) was highly effective as an
11 sion in SeV-infected cells demonstrated that Toll-like receptor 3, although essential for gene induct
12                                              Toll-like receptor 3, an innate pattern recognition rece
13                                              Toll-like receptor 3 and 4 agonists, tumor necrosis fact
14              We set to determine the role of toll-like receptor 3 and the binding of double-stranded
15 incorporating FADD is largely independent of Toll-like receptor 3 and the dsRNA-dependent kinase PKR,
16  and IPS-1 adaptor cytosolic pathway and the Toll-like receptor 3 and TIR domain-containing adaptor-i
17               Cathelicidins were induced via toll-like receptor-3 and were inhibited by IL-4/IL-13 th
18                              This applies to toll-like receptors 3 and 4 (TLR3, TLR4), which sense do
19 e disease viruses or after engagement of the Toll-like receptors 3 and 4 by double-stranded RNA and l
20 ), pathogen recognition receptors RIG-I, and Toll-like receptors 3 and 7.
21                      Cotransfection of human Toll-like receptors 3 and 9 (receptors for dsRNA and CpG
22 e innate pattern-recognition receptor TLR-3 (Toll-like receptor 3) and resulted in a marked inhibitio
23 terferon-beta (-/-), and wild-type mice with toll-like receptor 3 antibody neutralization.
24 re clearly defined with the observation that Toll-like receptor 3 can sense self RNA released from ne
25   We sought to evaluate an inhibitory mAb to Toll-like receptor 3, CNTO3157, on experimental HRV-16 i
26 gative lines were no longer able to induce a Toll-like receptor 3-dependent hyperinflammatory cytokin
27              Additionally, pretreatment with toll-like receptor 3/double-stranded RNA ligand inhibito
28                                            A toll-like receptor 3/double-stranded RNA ligand inhibito
29  double-stranded RNA from injured cells with toll-like receptor 3 drives the acute inflammatory respo
30                                              Toll-like receptor 3 expression was analyzed in postmort
31                                              Toll-like receptor 3 expression was higher in patients a
32 thimazole markedly decreased virally induced Toll-like receptor-3 expression and signaling and signif
33 otype and increased surface translocation of toll-like receptor 3 from the endosome to the surface.
34 in the toll-like receptor 2 gene (TLR2), the toll-like receptor 3 gene (TLR3), the toll-like receptor
35      In this issue, studies demonstrate that Toll-like receptor 3 has an important role in signaling
36 r the genetic dissection of inborn errors of Toll-like receptor 3 immunity.
37 ion of double-stranded RNA signaling through Toll-like receptor 3 is mediated by the viral protease N
38                                              Toll-like receptor-3 is critically involved in host defe
39 elanoma differentiation associated gene 5 or toll-like receptor 3, is the cytoplasmic sensor for intr
40                       C57BL/6J wild-type and toll-like receptor 3 knockout mice.
41                                          The Toll-like receptor 3 ligand, polyinosinic-polycytidylic
42 , such as an agonistic anti-CD40 antibody or Toll-like receptor 3 ligand.
43       To test this idea, we encapsulated the Toll-like receptor-3 ligand poly(inosinic:cytidylic acid
44  showed reduced stimulation of T cells after Toll-like receptor 3 ligation.
45 on caused by poly(I:C)-induced activation of toll-like receptor 3 localized in intracellular vesicles
46 se (IKK)-epsilon) are critically involved in Toll-like receptor-3-mediated IFN-beta production throug
47                    Alveolar macrophages from toll-like receptor 3 (-/-) mice had a lower early apopto
48 oceeded normally in macrophages deficient in Toll-like receptor 3 or 7.
49           Neither NK cells nor signaling via Toll-like receptor 3 or MyD88 were essential for viral c
50 ation of type I IFN responses through either Toll-like receptor 3 or retinoic acid-inducible gene I/m
51 s caused by defects in the activation of the Toll-like receptor 3 pathway, overall contributed to the
52  We observed that IHH possesses a functional Toll-like receptor 3 pathway.
53                                        TLR3 (Toll-like receptor 3) recognizes dsRNA, a potent indicat
54 on, or the binding of double-stranded RNA to Toll-like receptor 3, results in the coordinate activati
55         Compared with wild-type septic mice, toll-like receptor 3 septic mice had attenuated abdomina
56 lication of the HGC, in which we generated a Toll-like receptor 3-specific connectome useful for the
57 ion, and macrophage apoptosis was reduced in toll-like receptor 3 (-/-), TIR-domain-containing adapte
58     Unilateral lung contusion was induced in toll-like receptor 3 (-/-), TIR-domain-containing adapte
59        In the presence of 4-1BB ligation and Toll-like receptor 3 (TLR)3 and/or TLR4 triggering, CD8
60 model of brain inflammation by injecting the Toll-like receptor 3 (TLR-3) agonist polyinosinic:polycy
61                            Mice deficient in Toll-like receptor 3 (TLR-3) also developed this same sy
62  molecule that is critically involved in the Toll-like receptor 3 (TLR-3) and TLR-4 signaling pathway
63 an cell line competent for signaling through Toll-like receptor 3 (TLR-3) and TLR-5.
64             Experiments with astrocytes from Toll-like receptor 3 (TLR-3) knockout mice indicated tha
65                 The dsRNA signaling moieties Toll-like receptor 3 (TLR-3), retinoic acid-inducible ge
66  (ISG15) E3 ligase, HERC5, in the context of Toll-like receptor 3 (TLR3) activation and IFN induction
67 nhances double-stranded RNA (dsRNA)-mediated Toll-like receptor 3 (TLR3) activation.
68 -1 but did inhibit responses to poly(I.C), a Toll-like receptor 3 (TLR3) activator that does not sign
69 olyinosine-polycytidylic acid (poly(I:C)), a Toll-like receptor 3 (TLR3) agonist used as a mimetic to
70 rough in vivo administration of poly(I:C), a Toll-like receptor 3 (TLR3) agonist.
71 are emerging; in particular, dsRNA receptors Toll-like receptor 3 (TLR3) and cytosolic helicases expr
72 of the mRNA to evade activation of endosomal Toll-like receptor 3 (TLR3) and downstream innate immune
73 ich is released from damaged skin, activates Toll-Like Receptor 3 (TLR3) and its downstream effectors
74    Poly(I:C) acts through two dsRNA sensors, Toll-like receptor 3 (TLR3) and melanoma differentiation
75           This induction is mediated through toll-like receptor 3 (TLR3) and protein kinase R (PKR),
76      Viral double-stranded RNA, a ligand for Toll-like Receptor 3 (TLR3) and the cytoplasmic RNA rece
77 physical and functional relationship between Toll-like receptor 3 (TLR3) and the pattern recognition
78 naling of the pathogen recognition receptors Toll-like receptor 3 (TLR3) and TLR4.
79 ucing signals from intracellularly signaling Toll-like receptor 3 (TLR3) and TLR4.
80  UVB-damaged keratinocytes were dependent on Toll-like receptor 3 (TLR3) and Toll-like receptor adapt
81 anded RNA (dsRNA) induces phosphorylation of Toll-like receptor 3 (TLR3) at tyrosine 759 and subseque
82 ter activation in response to stimulation of Toll-like receptor 3 (TLR3) by extracellular double-stra
83                   The innate immune receptor Toll-like receptor 3 (TLR3) can be present on the surfac
84                                              Toll-like receptor 3 (TLR3) can signal the production of
85                   The structure of the human Toll-like receptor 3 (TLR3) ectodomain (ECD) was recentl
86 us 1 (HSV-1), children with inborn errors of toll-like receptor 3 (TLR3) immunity are prone to HSV-1
87                   Here, we report a role for toll-like receptor 3 (TLR3) in cone-rod dystrophy (CORD)
88 idylic acid sodium salt (poly I:C) to target Toll-like receptor 3 (TLR3) in endosomes.
89 N) leads to a reduction in the expression of Toll-like receptor 3 (TLR3) in macrophages from young do
90                                              Toll-like receptor 3 (TLR3) is a key effector of the inn
91                                              Toll-like receptor 3 (TLR3) is an innate immune system r
92                       Finally, we found that Toll-like receptor 3 (TLR3) is not required for either p
93                    We previously showed that Toll-like receptor 3 (TLR3) is the critical pattern reco
94 86, and CD40) expression and did not inhibit Toll-like receptor 3 (TLR3) ligand [poly(I:C)]-induced m
95 of innate immunity by viral infection or the toll-like receptor 3 (TLR3) ligand on liver regeneration
96                        Here we show that the Toll-like receptor 3 (TLR3) ligand poly(I:C) (PIC) induc
97                                              Toll-like receptor 3 (TLR3) mediates antiviral response
98 ants impaired IFN-beta production induced by Toll-like receptor 3 (TLR3) or TLR4 agonists but failed
99                      Defects in genes of the Toll-like receptor 3 (TLR3) pathway are associated with
100 ral dsRNA through two distinct pathways; the Toll-like receptor 3 (TLR3) pathway detects dsRNA phagoc
101 d loss-of-function studies, we find that the toll-like receptor 3 (TLR3) pathway enables efficient in
102 iation-associated protein 5 (RIG-I/MDA5) and Toll-like receptor 3 (TLR3) pathways.
103                                              Toll-like receptor 3 (TLR3) recognizes double-stranded R
104                                              Toll-like receptor 3 (TLR3) recognizes dsRNA and initiat
105 a (TNF-alpha) and has been implicated in the Toll-like receptor 3 (TLR3) response to double-stranded
106 horylation, leading to inefficient RIG-I and Toll-like receptor 3 (TLR3) responses.
107 tic properties, acts as a novel regulator of Toll-like receptor 3 (TLR3) signaling to interferon (IFN
108                      We investigated whether Toll-like receptor 3 (TLR3) stimulation would protect th
109                  Recognition of viral RNA by Toll-like receptor 3 (TLR3) triggers activation of the t
110        Recognition of double-stranded RNA by Toll-like receptor 3 (TLR3) will increase the production
111 y of RNA interference by directly activating Toll-like receptor 3 (TLR3), a double-stranded RNA immun
112 lock type I interferon signaling mediated by Toll-like receptor 3 (TLR3), a receptor we have previous
113 e 561 mRNA by exogenous dsRNA is mediated by Toll-like receptor 3 (TLR3), and it requires no new prot
114 tremendously when HEK293 cells overexpressed Toll-like receptor 3 (TLR3), and the increased secretion
115 sm through both its membrane-bound receptor, Toll-like receptor 3 (TLR3), as well as cytoplasmic rece
116  agonist that recognizes the cellular sensor Toll-like receptor 3 (TLR3), in regulating Valpha14iNKT
117 Differentiation-associated gene 5 (MDA5) and Toll-Like Receptor 3 (TLR3), induces the TANK-Binding Ki
118 d the modulatory effects of Th2 cytokines on Toll-like receptor 3 (TLR3), interferon-responsive facto
119 egfr1) siRNA suppressed CNV via cell-surface toll-like receptor 3 (TLR3), its adaptor TRIF, and induc
120 erleukin-1 (IL-1)/Toll receptor superfamily, Toll-like receptor 3 (TLR3), recognizes double-stranded
121 his family of pattern recognition receptors, toll-like receptor 3 (TLR3), recognizes viral double-str
122 se HCV dsRNAs also induced the expression of Toll-like receptor 3 (TLR3), retinoic acid-inducible gen
123 wnstream of several viral sensors, including Toll-like receptor 3 (TLR3), RIG-I, and MDA5.
124 ors, respectively, and with the exception of Toll-like receptor 3 (TLR3), signal via the adaptor mole
125 CL22, CD274, and CD273 and downregulation of Toll-like receptor 3 (TLR3), TLR5, and TLR7.
126 eltaE3L is unaffected by genetic ablation of Toll-like receptor 3 (TLR3), TRIF, TLR9, and MyD88.
127                         Influenza stimulates toll-like receptor 3 (TLR3), which can increase RhoA act
128 merous interferon-regulated genes, including Toll-like receptor 3 (Tlr3), which encodes an innate imm
129 mal organization to the selective control of toll-like receptor 3 (TLR3)- and TLR4-mediated proinflam
130 rmore, preexposure of LC to L3 did not alter Toll-like receptor 3 (TLR3)- or TLR4-mediated expression
131     These interferon responses attributed to toll-like receptor 3 (TLR3)-activated Kupffer and liver
132                    Inhibition of BRD4 blocks Toll-like receptor 3 (TLR3)-dependent neutrophilia and R
133                             Inborn errors in Toll-like receptor 3 (TLR3)-IFN type I and III pathways
134 hat West Nile virus (WNV) is able to inhibit Toll-like receptor 3 (TLR3)-mediated activation of inter
135            Here we report that EV68 inhibits Toll-like receptor 3 (TLR3)-mediated innate immune respo
136 nse to viral infection is often triggered by Toll-like receptor 3 (TLR3)-mediated signaling by double
137 Huh7 hepatoma cells by ectopic expression of Toll-like receptor 3 (TLR3).
138 ed by signalling through the dsRNA receptor, toll-like receptor 3 (TLR3).
139 ) from necrotic keratinocytes that activates Toll-like receptor 3 (TLR3).
140 f the endosomal pattern recognition receptor Toll-like receptor 3 (TLR3).
141 een identified as an endogenous activator of Toll-like receptor 3 (TLR3).
142 ed (ds) RNA-induced innate responses through Toll-like receptor 3 (TLR3).
143 g the caspase-11 pathway in vivo with LPS or Toll-like receptor-3 (TLR3) agonist resulted in high mor
144                                              Toll-like receptor-3 (TLR3) is crucial for the innate im
145                                              Toll-like receptor-3 (TLR3) senses double-stranded RNA,
146                                We found that Toll-like receptor-3 (TLR3) senses HCV infection in cult
147                                              Toll-like receptor-3 (TLR3), a member of the pathogen re
148                   The innate immune receptor Toll-like-Receptor 3 (TLR3) was upregulated after ZIKV i
149 s well as following exposure to poly(I.C) (a Toll-like receptor 3 [TLR3] stimulus) and 5' poly(U) HCV
150 lectively on keratinocytes triggered through Toll-like receptor 3(TLR3).
151 pothesized that small-molecule activators of toll-like receptor 3, together with external microenviro
152  kinase, 2'5'-oligoadenylate synthetase, and Toll-like receptor 3, transcripts that encode dsRNA-resp
153  is sensed by the human epithelial cells via Toll-like receptor 3, triggering Interferon Regulating F
154 eover, a direct interaction between PAR2 and Toll-like receptor 3 was observed.

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