ライフサイエンスコーパス: Tourette syndrome

1 cularly those involving motor systems (e.g., Tourette syndrome).

2 inhibit automatic behaviors, such as tics in Tourette syndrome.

3 pression, obsessive-compulsive disorder, and Tourette syndrome.

4 n FSIs has been found in human patients with Tourette syndrome.

5 regions are important in the pathogenesis of Tourette syndrome.

6 sential blepharospasm, hemifacial spasm, and Tourette syndrome.

7 lse control is volitional tic suppression in Tourette syndrome.

8 ocus heterogeneity or a polygenic origin for Tourette syndrome.

9 and evaluated for a possible involvement in Tourette syndrome.

10 ronto-striatal networks hyperconnectivity in Tourette syndrome.

11 tem to study how motor tics are generated in Tourette syndrome.

12 rders, especially schizophrenia, autism, and Tourette syndrome.

13 on in unmedicated patients with Gilles de la Tourette syndrome.

14 gain in HIV infection, sleep disorders, and Tourette syndrome.

15 spired new research on functional anatomy of Tourette syndrome.

16 iology in schizophrenia, anxiety, autism and Tourette syndrome.

17 predict or influence longitudinal outcome of Tourette syndrome.

18 rders associated with Huntington disease and Tourette syndrome.

19 proach could improve motor and vocal tics in Tourette syndrome.

20 and behavioural expressions of Gilles de la Tourette syndrome.

21 e and effective intervention for adults with Tourette syndrome.

22 ole of the basal ganglia in causing tics and Tourette syndrome.

23 molecular and cellular mechanisms underlying Tourette syndrome.

24 the neurobiology, genetics and treatment of Tourette syndrome.

25 lative to comparison subjects, patients with Tourette syndrome activated more strongly the frontal co

26 We studied 11 patients with Tourette syndrome and 11 healthy controls.

27 g was used to scan 120 participants (51 with Tourette syndrome and 69 comparison subjects) as they ei

28 icantly associated with disinhibition, while Tourette syndrome and ADHD risk scores were not.

29 Motor tics are a cardinal feature of Tourette syndrome and are traditionally associated with

30 y experience with patients with Gilles de la Tourette syndrome and covers its definition and history

31 habitual behavioural control in Gilles de la Tourette syndrome and formally tested the hypothesis of

32 r, eye blinking, in children and adults with Tourette syndrome and in healthy comparison subjects.

33 ychotic-medicated patients with Gilles de la Tourette syndrome and matched controls.

34 ons contribute to movement disorders such as Tourette syndrome and obsessive compulsive disorder, in

35 ar stereotypies manifest in animal models of Tourette syndrome and obsessive compulsive disorder.

36 the temporal properties of tics expressed in Tourette syndrome and other tic disorders have eluded cl

37 the abnormal striatal inhibition typical of Tourette syndrome and other tic disorders results in tic

38 motor tics resembling those expressed during Tourette syndrome and other tic disorders.

39 of haloperidol, one available treatment for Tourette syndrome and primarily a D2 receptor antagonist

40 odeling movement sequences and treatments in Tourette syndrome and related disorders.

41 on have been observed in human patients with Tourette syndrome and rodent models of dystonia.

42 zheimer and Parkinson diseases, Gilles de la Tourette syndrome, and addiction.

43 s has also been implicated in schizophrenia, Tourette syndrome, and bipolar disorder.

44 regulated in ischemic stroke, migraine, and Tourette syndrome are shown to be associated with distin

45 the other neuropsychiatric symptoms seen in Tourette syndrome are thought to have an organic basis,

46 uclear families, which were collected by the Tourette Syndrome Association International Consortium f

47 s conducted on 77 sib pairs collected by the Tourette Syndrome Association International Consortium f

48 d a replication sample of 186 trios from the Tourette Syndrome Association International Consortium o

49 Tics in Tourette syndrome begin in childhood, peak in early adol

50 ficit/Hyperactivity Disorder, Schizophrenia, Tourette Syndrome, Bipolar Disorder, or persons at high

51 re the neural basis of tics in patients with Tourette syndrome by using event-related functional MRI

52 ession was studied in 22 adult subjects with Tourette syndrome by using functional magnetic resonance

53 g in frontal and parietal lobes in groups of Tourette syndrome children relative to controls.

54 Tourette syndrome/chronic tic disorder (TS/CT) and obses

55 rs of a 3-generation pedigree with 7 showing Tourette syndrome/chronic tic phenotype (TS-CTD) were ev

56 update summarizes progress in understanding Tourette syndrome clinical characteristics, etiology, an

57 nglia networks in patients with Gilles de la Tourette syndrome compared with controls.

58 tual behaviour in patients with Gilles de la Tourette syndrome correlated with greater structural con

59 Tourette syndrome/CT and OCD cluster in families.

60 A rare genetic form of Tourette syndrome due to L-histidine-decarboxylase mutat

61 riatal activity is increased in persons with Tourette syndrome during the inhibition of eye blinks.

62 and latent class analyses were conducted in Tourette syndrome families and replicated in an independ

63 Polygenic risk scores derived from a Tourette syndrome genome-wide association study (GWAS) w

64 mary outcome variable was total score on the Tourette Syndrome Global Scale.

65 Gilles de la Tourette syndrome (GTS) is a complex neuropsychiatric di

66 Gilles de la Tourette syndrome (GTS) is a neurodevelopmental disorder

67 Gilles de la Tourette syndrome (GTS) is a potentially debilitating ne

68 Gilles de la Tourette syndrome (GTS) is characterized by multiple mot

69 erlying the involuntary tics of Gilles de la Tourette syndrome (GTS) remains unknown.

70 e concordant for a diagnosis of Gilles de la Tourette syndrome (GTS).

71 ied in a family suffering from Guilles de la Tourette syndrome (GTS).

72 An individual diagnosed with Tourette syndrome has been described carrying a constitu

73 tions, such as major depressive disorder and Tourette syndrome, have more limited, but promising resu

74 g the translocation exhibit features seen in Tourette syndrome including motor tics, vocal tics, and

75 Gilles de la Tourette syndrome is a clinically heterogeneous disorder

76 Tourette syndrome is a neuropsychiatric disorder charact

77 Tourette syndrome is a prototypic neuropsychiatric disor

78 Evidence suggests that Tourette syndrome is characterized by an increase in dop

79 Enhanced multi-component behaviour in Tourette syndrome is likely based on an enhanced ability

80 Phenotypic heterogeneity in Tourette syndrome is partly due to complex genetic relat

81 ropsychiatric conditions: Parkinson disease, Tourette syndrome, major depressive disorder, and obsess

82 e needed to further understand their role in Tourette syndrome management.

83 the gamma-aminobutyric acid-ergic system in Tourette syndrome may conceivably underlie the symptoms

84 ehaviour was collected from 15 patients with Tourette syndrome (mean age = 30.40 +/- 11.10) and 15 he

85 y due to complex genetic relationships among Tourette syndrome, obsessive-compulsive disorder (OCD),

86 forms of neuropsychiatric disease, including Tourette syndrome, obsessive-compulsive spectrum disorde

87 METHOD: Assessments for Tourette syndrome, OCD, and ADHD symptoms were conducted

88 Assessments for Tourette syndrome, OCD, and ADHD symptoms were conducted

89 itability and polygenic load associated with Tourette syndrome, OCD, and ADHD were estimated.

90 in diseases such as parkinsonism, dystonia, Tourette syndrome, or schizophrenia.

91 variety of neurological disorders including Tourette Syndrome, Parkinson's disease and schizophrenia

92 sal ganglia and thalamus are disinhibited in Tourette syndrome patients.

93 The symmetry phenotype correlated with Tourette syndrome polygenic load and was present in othe

94 Mothers of Tourette syndrome probands had high rates of symmetry (4

95 mena were found to have important impacts on Tourette syndrome quality of life.

96 on Depression Rating Scale, the Gilles de la Tourette Syndrome-Quality of Life Scale, and the Global

97 g that this phenotype may reflect additional Tourette syndrome (rather than OCD) genetic liability th

98 This survey of recent literature addressing Tourette syndrome reflects clinical and laboratory findi

99 ns such as obsessive-compulsive disorder and Tourette syndrome remain uncertain.

100 he substantia nigra, Parkinson's disease and Tourette syndrome, show gender differences and age-relat

101 fied two heritable endophenotypes related to Tourette syndrome that cross traditional diagnostic boun

102 c interneurons are reported in patients with Tourette syndrome, the normal functions of these interne

103 Compared with 273 patients with Tourette syndrome, those with PMDs resembling tics were

104 To investigate the transmission of Tourette syndrome (TS) and associated disorders within f

105 lities are implicated in the pathogenesis of Tourette syndrome (TS) and chronic multiple tics.

106 Tic disorders, including Tourette syndrome (TS) and chronic tic disorders (CTDs),

107 g symptoms of otherwise treatment-refractory Tourette syndrome (TS) has been documented in several pu

108 Previous studies of brain structure in Tourette syndrome (TS) have produced mixed results, and

109 The etiology of Tourette syndrome (TS) involves disturbances in the stru

110 nce that the pathophysiology of Gilles de la Tourette syndrome (TS) involves structural and functiona

111 Tourette syndrome (TS) is a childhood-onset tic disorder

112 Tourette syndrome (TS) is a chronic neurologic disorder

113 Tourette syndrome (TS) is a common, chronic neuropsychia

114 Tourette syndrome (TS) is a complex childhood neurodevel

115 Tourette syndrome (TS) is a developmental disorder chara

116 Tourette syndrome (TS) is a developmental neurological d

117 Tourette syndrome (TS) is a developmentally regulated ne

118 Tourette syndrome (TS) is a model neuropsychiatric disor

119 Tourette syndrome (TS) is a neurodevelopmental disorder

120 Tourette syndrome (TS) is a neurodevelopmental disorder

121 Tourette syndrome (TS) is a neuropsychiatric disorder ch

122 Tourette syndrome (TS) is an inherited developmental neu

123 Tourette syndrome (TS) is characterized by high rates of

124 Tourette syndrome (TS) is characterized by multiple moto

125 Tourette syndrome (TS) is characterized by tics, sensori

126 Gilles de la Tourette syndrome (TS) is characterized by tics, which a

127 e is considerable evidence that Gilles de la Tourette syndrome (TS) is due to frontal-striatal dysfun

128 The pathophysiology of Tourette syndrome (TS) is thought to involve disturbance

129 Tourette syndrome (TS) prominently involves dopaminergic

130 We analyzed rare CNVs in Tourette syndrome (TS) to identify novel risk regions an

131 e investigated the role of the cerebellum in Tourette syndrome (TS), a condition defined by the prese

132 om of the classic neuropsychiatric disorder, Tourette syndrome (TS), and constitute an example of dis

133 lia and cortical targets in individuals with Tourette syndrome (TS), but less is known regarding the

134 ctural finding in the brain of patients with Tourette syndrome (TS), but the cellular abnormalities t

135 y risk-conferring common genetic variants in Tourette syndrome (TS), requiring the adoption of altern

136 as raised whether patients with Gilles de la Tourette syndrome (TS), who show tic-like movements, are

137 s are likely involved in the pathogenesis of Tourette syndrome (TS).

138 Slit and Trk-like 1) as a candidate gene for Tourette Syndrome (TS).

139 orbidity: autism spectrum disorder (ASD) and Tourette syndrome (TS).

140 d to obsessive-compulsive disorder (OCD) and Tourette syndrome (TS).

141 investigate this conjecture in children with Tourette syndrome (TS).

142 improved by plasma exchange (mean change on Tourette syndrome unified rating scale of 49%).

143 Tourette syndrome was associated with increased risk of

144 e disorder (OCD) or tic disorders, including Tourette syndrome, were randomly assigned treatment with

145 ently been implicated in the pathogenesis of Tourette syndrome, whereas motor and sensorimotor cortic

146 opsychology, and the effects of Gilles de la Tourette syndrome with studies showing that the quality

147 the model also shows the utility of casting Tourette syndrome within a system-level perspective rath