ライフサイエンスコーパス: Treponema pallidum

1 ens (e.g. Helicobacter pylori, C. jejuni and Treponema pallidum).

2 disease caused by the spirochetal bacterium Treponema pallidum.

3 ermini of the 17- and 47-kDa lipoproteins of Treponema pallidum.

4 from the emergence of phenotypic variants of Treponema pallidum.

5 se of humans caused by spirochetal bacterium Treponema pallidum.

6 lated oral spirochetes (PROS) are related to Treponema pallidum.

7 ctivation by motile Borrelia burgdorferi and Treponema pallidum.

8 or by identification of the causative agent, Treponema pallidum.

9 n identified previously in OM fractions from Treponema pallidum.

10 nd characterized in Treponema phagedenis and Treponema pallidum.

11 vage site, and has 26% identity with TmpC of Treponema pallidum.

12 eraction datasets of Helicobacter pylori and Treponema pallidum.

13 philis is caused by the spirochetal pathogen Treponema pallidum.

14 lopment following intradermal challenge with Treponema pallidum.

15 hesin Tp0751 within the spirochete bacterium Treponema pallidum.

16 e of the related syphilis-causing spirochete Treponema pallidum.

17 ) for herpes simplex virus, and 27 (19%) for Treponema pallidum; 12 (8%) were positive for > 1 organi

18 Neurosyphilis was defined as detection of Treponema pallidum 16S RNA in CSF or CSF white blood cel

19 Synthetic analogs of lipopeptides from Treponema pallidum also inhibited Ag processing.

20 The Tp34 (TP0971) membrane lipoprotein of Treponema pallidum, an obligate human pathogen and the a

21 Treponema pallidum, an obligate parasite of humans and t

22 Immunoblots using anti-FlaA serum from Treponema pallidum and a lysate of B. burgdorferi showed

23 is increasing evidence that lipoproteins of Treponema pallidum and Borrelia burgdorferi are key infl

24 Lipoproteins of Treponema pallidum and Borrelia burgdorferi possess pote

25 spirochetes including the syphilis bacterium Treponema pallidum and Lyme disease pathogen Borrelia bu

26 of Escherichia coli, Haemophilus influenzae, Treponema pallidum and Mycoplasma genitalium.

27 Treponema pallidum and other members of the genera Trepo

28 of the organisms Caenorhabditis elegans and Treponema pallidum and to differ by one residue from PEP

29 Treponema pallidum and Treponema denticola encode within

30 me disease (Borrelia burgdorferi), syphilis (Treponema pallidum) and leptospirosis (Leptospira interr

31 r antibodies to herpes simplex virus type 2, Treponema pallidum, and hepatitis B, tests for hepatitis

32 ion of DNA targets from Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus (HSV) types

33 ction (M-PCR) assay for Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus (HSV) was c

34 eaction assay to detect Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus (HSV); sera

35 al ulcer disease (GUD), Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus, was used t

36 ly related proteins in Borrelia burgdorferi, Treponema pallidum, and Leptospira kirschneri.

37 eins/lipopeptides from Borrelia burgdorferi, Treponema pallidum, and Mycoplasma fermentans activated

38 y of bacteria, such as Borrelia burgdorferi, Treponema pallidum, and Mycoplasma fermentans.

39 Western blot analysis using Treponema pallidum anti-FlaA serum indicated that FlaA w

40 d electronic reader for detection of HIV and Treponema pallidum antibodies in 450 previously characte

41 um samples and compared to reference HIV and Treponema pallidum antibody detection methods.

42 mology with the sequences of E. coli Dps and Treponema pallidum antigen TpF1 or 4D, proteins which as

43 rex Diagnostics) that uses three recombinant Treponema pallidum antigens (TpN15, TpN17, and TpN47) an

44 ively detects IgG and IgM antibodies against Treponema pallidum antigens in human serum and plasma.

45 lopment of the T-cell response to a panel of Treponema pallidum antigens over the course of syphilis

46 resence of antibodies reactive with specific Treponema pallidum antigens.

47 Phagocytosis of Treponema pallidum by cytokine-activated macrophages aid

48 ly detected ulcers were tested for HSV-2 and Treponema pallidum by polymerase chain reaction (PCR).

49 Unlike many pathogenic bacteria, Treponema pallidum cannot synthesize riboflavin; we rece

50 rom a few eubacteria (Clostridium difficile, Treponema pallidum, Chlorobium tepidum).

51 The genomes of Treponema denticola and Treponema pallidum contain a gene, licCA, which is predi

52 Surprisingly, opsonophagocytosis of Treponema pallidum did not elicit a discernible cell dea

53 Treponema pallidum DNA from even small numbers of organi

54 rase chain reaction (PCR) was used to detect Treponema pallidum DNA in cerebrospinal fluid (CSF) from

55 e used real-time quantitative PCR to measure Treponema pallidum DNA levels in rabbits infected intrat

56 The prevalence of Treponema pallidum DNA was examined in the following sev

57 Treponema pallidum DNA was isolated from 158 patients wi

58 Previous studies demonstrated that Treponema pallidum encodes a cluster-9 (C9) ABC transpor

59 eran Affairs facility, finding 5.5% reactive Treponema pallidum enzyme immunoassay (EIA) tests.

60 e evaluated a molecular subtyping system for Treponema pallidum for its ability to differentiate betw

61 ficiency virus gene (HIV), and the syphilis (Treponema pallidum) gene.

62 The recent discovery that the Treponema pallidum genome encodes 12 orthologs of the Tr

63 s were predicted by computer analysis of the Treponema pallidum genome.

64 obtained with standard laboratory tests (the Treponema pallidum haemagglutination assay [TPHA] and th

65 polymerase chain reaction (M-PCR) to detect Treponema pallidum, Haemophilus ducreyi, and herpes simp

66 varied genome sizes (Mycoplasma pneumoniae, Treponema pallidum, Helicobacter pylori, Campylobacter j

67 tion assay (CSF-TPPA) is sensitive and a CSF Treponema pallidum hemagglutination assay (CSF-TPHA) tit

68 pid plasma reagin [RPR] titer > or = 1:8 and Treponema pallidum hemagglutination assay [TPHA]/fluores

69 asma reagin titer > or = 1 :8 and a positive Treponema pallidum hemagglutination assay or indirect fl

70 unts, and serologic assays for antibodies to Treponema pallidum, herpes simplex virus, and hepatitis

71 be a false-positive reaction by nonreactive Treponema pallidum immobilization and fluorescent trepon

72 polymerase chain reaction (PCR) testing for Treponema pallidum in cerebrospinal fluid (CSF) samples.

73 sensitive and specific PCR method to detect Treponema pallidum in clinical specimens was developed.

74 may prove to be useful techniques to detect Treponema pallidum in intraocular specimens.

75 hilis and invasion of cerebrospinal fluid by Treponema pallidum in patients with human immunodeficien

76 ons of syphilis and the invasive behavior of Treponema pallidum in tissue culture systems reflect the

77 The species Treponema pallidum includes three subspecies (pallidum,

78 Treponema pallidum includes three subspecies of antigeni

79 d to examine mechanisms that likely underlie Treponema pallidum-induced immune cell activation and co

80 Identification of infants with Treponema pallidum infection of the central nervous syst

81 philis is an inflammatory eye disease due to Treponema pallidum infection.

82 Treponema pallidum infections can have severe complicati

83 The 15-kDa lipoprotein of Treponema pallidum is a major immunogen during natural s

84 Treponema pallidum is cleared from sites of infection by

85 ions of syphilis and the infecting strain of Treponema pallidum is not known.

86 e genome of the etiologic agent of syphilis, Treponema pallidum, is compact and devoid of many metabo

87 In syphilis research, the Nichols strain of Treponema pallidum, isolated in 1912, has been the most

88 Treponema pallidum, its membrane lipoproteins, and synth

89 The molecular masses of Tromp1, three Treponema pallidum lipoproteins, and a bovine serum albu

90 that this protein shares similarity with the Treponema pallidum LRR (LRR(TP)) family of proteins and

91 rrelia burgdorferi and by B. burgdorferi and Treponema pallidum lysates but were poorly activated by

92 The nucleotide sequence of the Treponema pallidum mcp2 gene was determined.

93 followed by microhemagluttination assay for Treponema pallidum (MHA-TP) testing of RPR-reactive sera

94 compared the microhemagglutination assay for Treponema pallidum (MHA-TP), a treponemal test, with two

95 test and the microhemagglutination assay for Treponema pallidum (MHA-TP).

96 tive by another treponema-specific test, the Treponema pallidum microhemagglutination assay.

97 s were used: a nonimmune group infected with Treponema pallidum (NI/TP), a nonimmune group injected w

98 ettsia rickettsii, Chlamydia group positive, Treponema pallidum, Orientia tsutsugamushi, Fransciscell

99 TroA (Tromp1) was initially reported to be a Treponema pallidum outer membrane protein with porin-lik

100 Immunization with purified Treponema pallidum outer membrane vesicles (OMV) has pre

101 sequences from a 26-kDa protein in isolated Treponema pallidum outer membranes (OMs).

102 Recent reports that isolated Treponema pallidum outer membranes contain an ortholog f

103 with two other treponemal tests, the Serodia Treponema pallidum particle agglutination (TP-PA) assay

104 chemiluminescence immunoassay (CLIA), and a Treponema pallidum particle agglutination (TP-PA) test.

105 ther tested by rapid plasma reagin (RPR) and Treponema pallidum particle agglutination (TP.PA) testin

106 flex testing with rapid plasma reagin (RPR), Treponema pallidum particle agglutination (TPPA), and fl

107 [FTA] assay [Zeus Scientific, Raritan, NJ], Treponema pallidum particle agglutination [TP-PA; Fujire

108 and Trep-Sure EIA) and three manual assays (Treponema pallidum particle agglutination [TP-PA], fluor

109 ed data suggest that the cerebrospinal fluid Treponema pallidum particle agglutination assay (CSF-TPP

110 al serology underwent reflexive testing with Treponema pallidum particle agglutination assay (TP-PA)

111 , RPR-negative serology were tested with the Treponema pallidum particle agglutination assay (TP-PA)

112 sly evaluated using the rapid plasma reagin, Treponema pallidum particle agglutination, and chemilumi

113 ative rapid plasma reagin (RPR) test and the Treponema pallidum passive particle agglutination (TP-PA

114 Western blot analysis using antisera to Treponema pallidum PF proteins along with N-terminal ami

115 complete genomes of Borrelia burgdorferi and Treponema pallidum provides a number of insights into ev

116 Treponema pallidum rapidly disseminates from a genital s

117 e have previously observed that while native Treponema pallidum rare outer membrane protein 1 (Tromp1

118 Treponema pallidum rare outer membrane protein 1 (Tromp1

119 Identification of Treponema pallidum rare outer membrane proteins (OMPs) h

120 Definitive identification of Treponema pallidum rare outer membrane proteins (OMPs) h

121 aggregates the low-density membrane-spanning Treponema pallidum rare outer membrane proteins (TROMPs)

122 Treponema pallidum reacts poorly with the antibodies pre

123 la, as well as the parental ortholog for the Treponema pallidum repeat (Tpr) family in the syphilis s

124 It has been shown that the Treponema pallidum repeat protein K (TprK) differs in se

125 When used as an immunogen, Treponema pallidum repeat protein K (TprK) has been show

126 ts immunized with the Seattle Nichols strain Treponema pallidum repeat protein K (TprK) were previous

127 We previously identified Treponema pallidum repeat proteins TprC/D, TprF, and Tpr

128 The tpr (Treponema pallidum repeat) genes are believed to code fo

129 This rapid assay detected HIV and Treponema pallidum serum antibodies with sensitivities o

130 of the spirochaetes Borrelia burgdorferi and Treponema pallidum show strong strand-specific skews in

131 SORs from Desulfovibrio gigas and Treponema pallidum showed similar turnover rates when su

132 creening tests (antilipoidal antibodies) and Treponema pallidum-specific tests (anti-T. pallidum anti

133 Transcriptional regulation in Treponema pallidum ssp. pallidum is poorly understood, p

134 onfers macrolide resistance is present in >1 Treponema pallidum strain, 58 isolates collected between

135 techniques that allow the differentiation of Treponema pallidum strains on the basis of two variable

136 059G) in both copies of the 23S rRNA gene in Treponema pallidum strains.

137 n lesions or presence of ulcers negative for Treponema pallidum subsp pertenue on PCR, and active yaw

138 of the 15-kDa gene have been determined for Treponema pallidum subsp. pallidum (Nichols and Bal-3 st

139 tive transport related operon (tro) locus of Treponema pallidum subsp. pallidum (Nichols strain) (Tp)

140 transcript levels in the syphilis spirochete Treponema pallidum subsp. pallidum (Nichols) isolated fr

141 Transcriptional analysis of the tpr genes in Treponema pallidum subsp. pallidum (referred to here as

142 s, is morphologically indistinguishable from Treponema pallidum subsp. pallidum (T. pallidum), the hu

143 A 38-kDa lipoprotein of Treponema pallidum subsp. pallidum (T. pallidum), the sy

144 this bacterial infection, which is caused by Treponema pallidum subsp. pallidum (TPA), has been re-em

145 The clearance of Treponema pallidum subsp. pallidum from early syphilis l

146 ons have demonstrated that immunization with Treponema pallidum subsp. pallidum glycerophosphodiester

147 The spirochete Treponema pallidum subsp. pallidum is the causative agen

148 Treponema pallidum subsp. pallidum is the causative agen

149 and expression of the gene encoding a 28-kDa Treponema pallidum subsp. pallidum rare outer membrane p

150 and sequencing of the gene encoding a 31-kDa Treponema pallidum subsp. pallidum rare outer membrane p

151 908 of the 1,039 proteins in the proteome of Treponema pallidum subsp. pallidum using a protein array

152 ly mapping the 47-kDa lipoprotein (Tpp47) of Treponema pallidum subsp. pallidum using an overlapping

153 ction of the predicted lipoprotein TP0136 of Treponema pallidum subsp. pallidum were investigated bas

154 ent Tpr proteins in the syphilis spirochete, Treponema pallidum subsp. pallidum, may have important i

155 syphilis, caused by the spirochete bacterium Treponema pallidum subsp. pallidum, remains a public hea

156 In Treponema pallidum subsp. pallidum, the agent of syphili

157 Treponema pallidum subsp. pallidum, the agent of syphili

158 The tprK gene of Treponema pallidum subsp. pallidum, the causative agent

159 Treponema pallidum subsp. pallidum, the causative agent

160 The tpr gene family of Treponema pallidum subsp. pallidum, the causative agent

161 n occurs in surface-exposed proteins, and in Treponema pallidum subsp. pallidum, the syphilis agent,

162 The tprK gene in the syphilis spirochete, Treponema pallidum subsp. pallidum, undergoes antigenic

163 uence of the bacterium that causes syphilis, Treponema pallidum subsp. pallidum.

164 C4D guinea pigs to cutaneous infection with Treponema pallidum subsp. pertenue Haiti B strain.

165 ribing the use of DNA sequencing to identify Treponema pallidum subsp. pertenue-specific sequences in

166 Although the three Treponema pallidum subspecies (T. pallidum subsp. pallid

167 Treponema pallidum subspecies pallidum (Nichols) chromos

168 The tprK gene sequence of Treponema pallidum subspecies pallidum (T. pallidum) is

169 thogen-related oral spirochetes (PROS, using Treponema pallidum subspecies pallidum monoclonal antibo

170 ntigen, designated Tp92, was identified from Treponema pallidum subspecies pallidum.

171 Haemophilus ducreyi (HD) and Treponema pallidum subspecies pertenue (TP) are major ca

172 Yaws, caused by Treponema pallidum subspecies pertenue and diagnosed by

173 mergence of resistance to macrolides against Treponema pallidum subspecies pertenue was seen.

174 disease (Borrelia burgdorferi) and syphilis (Treponema pallidum) swim through viscous fluids, such as

175 multaneously for multiple antigens of HIV-1, Treponema pallidum (syphilis), and hepatitis C virus (HC

176 eisseria gonorrhoeae, Chlamydia trachomatis, Treponema pallidum (syphilis), herpes simplex virus 2, a

177 In Treponema pallidum (T. pallidum), the causative agent of

178 purified outer membrane vesicles (OMV) from Treponema pallidum (T.p.) could elicit Abs capable of ki

179 s is a chronic bacterial infection caused by Treponema pallidum that is endemic in low-income countri

180 Treponema pallidum, the bacterial agent of syphilis, can

181 Treponema pallidum, the bacterial agent of syphilis, is

182 mography (cryo-ET) was utilized to visualize Treponema pallidum, the causative agent of syphilis, at

183 Tp0655 of Treponema pallidum, the causative agent of syphilis, is

184 Treponema pallidum, the causative agent of syphilis, is

185 Genome sequence analysis of Treponema pallidum, the causative agent of syphilis, sug

186 Treponema pallidum, the causative agent of venereal syph

187 Insights into the genomic adaptive traits of Treponema pallidum, the causative bacterium of syphilis,

188 In the causative agent of syphilis, Treponema pallidum, the gene encoding 3-phosphoglycerate

189 The outer membrane of Treponema pallidum, the non-cultivable agent of venereal

190 of the 32-kDa membrane lipoprotein (Tp32) of Treponema pallidum, the syphilis bacterium.

191 The ability of Treponema pallidum, the syphilis spirochete to colonize

192 The finding that Treponema pallidum, the syphilis spirochete, contains 12

193 examine the native cellular organization of Treponema pallidum, the syphilis spirochete.

194 In Treponema pallidum, this protein (TatT) is a water-solub

195 in this cluster are most similar to those of Treponema pallidum (Tp) and Bacillus subtilis (Bs).

196 reading frame (cheX) that is homologous with Treponema pallidum (Tp) and Borrelia burgdorferi (Bb) ch

197 ittle is known about the mechanisms by which Treponema pallidum (Tp), the causative agent of syphilis

198 nd composition of the outer membrane (OM) of Treponema pallidum (Tp), the noncultivable agent of vene

199 A 38-kDa lipoprotein of Treponema pallidum (Tp38) was predicted to be a periplas

200 he antigenicity of the 15-kDa lipoprotein of Treponema pallidum (Tpp15 or TpN15) was comprehensively

201 Two new tprD alleles have been identified in Treponema pallidum: tprD2 is found in 7 of 12 T. pallidu

202 The Treponema pallidum tro operon encodes an ABC transporter

203 logy to most of the previously characterized Treponema pallidum tro operon.

204 We previously demonstrated that Treponema pallidum TroA is a periplasmic metal-binding p

205 ith sequence similarity at its C terminus to Treponema pallidum TroR.

206 The tprK gene in Treponema pallidum undergoes antigenic variation.

207 The complete genome sequence of Treponema pallidum was determined and shown to be 1,138,

208 A serum sample containing antibody against Treponema pallidum was reported as positive by 70% of th

209 A molecular-based subtyping system for Treponema pallidum was used during an investigation of i

210 d-type fliG genes from T. denticola and from Treponema pallidum were cloned into this expression plas

211 882 of the 1,039 proteins in the proteome of Treponema pallidum were examined.

212 vestigated the interaction of the spirochete Treponema pallidum with the ECM component laminin.