ライフサイエンスコーパス: Trypanosoma

1 ection system of parasitic protozoa, such as trypanosoma and leishmania parasites.

2 ypanosomatids, which include human pathogens Trypanosoma and Leishmania This makes Paratrypanosoma un

3 estral characters such as peptidases between Trypanosoma and Leishmania, genomic differences that wer

4 ude medically important members of the genus Trypanosoma and Leishmania, the 26/28S large subunit rib

5 ll-studied in non-unikont parasites, such as Trypanosoma and Plasmodium, and found important in their

6 Most of the samples were active against Trypanosoma b.

7 Trypanosoma brucei (T. brucei) is responsible for the fa

8 ng drug target within the parasitic protozoa Trypanosoma brucei (T. brucei), the causative agent for

9 e atomic structure of its close homolog from Trypanosoma brucei (TbASNA) at 2.2 A.

10 rominent defence of the unicellular parasite Trypanosoma brucei against the host immune system is a d

11 The Trypanosoma brucei aminopurine transporter P2/TbAT1 has

12 ct life cycle stages of two human parasites; Trypanosoma brucei and Leishmania mexicana.

13 el can be applied to the characterization of Trypanosoma brucei and Leishmania spp. ribosomes as well

14 wledge largely stems from the human pathogen Trypanosoma brucei and mouse experimental models.

15 zation of this channel to acidocalcisomes of Trypanosoma brucei and suggest that caution should be ex

16 The parasitic trypanosomes Trypanosoma brucei and T. cruzi are responsible for sign

17 roducts exhibit significant activity against Trypanosoma brucei and T. cruzi, featuring favorable dru

18 o be essential for survival and virulence of Trypanosoma brucei and, in Trypanosoma cruzi, PDEC2 was

19 Mitochondrial ribosomes of Trypanosoma brucei are composed of 9S and 12S rRNAs, eub

20 Trypanosoma brucei belongs to a group of protists that s

21 Trypanosoma brucei BILBO1 (TbBILBO1) is an essential com

22 h a single-digit micromolar activity against Trypanosoma brucei brucei (EC50 = 2.97 muM), thus being

23 een of approximately 87000 compounds against Trypanosoma brucei brucei identified a number of promisi

24 eening of a focused protease library against Trypanosoma brucei brucei in culture.

25 ate immunity against the veterinary pathogen Trypanosoma brucei brucei is conferred by trypanosome ly

26 d low micromolar levels of inhibition of the Trypanosoma brucei brucei parasite grown in culture.

27 ts: I172V, I172A, L232A, and P168A (TIM from Trypanosoma brucei brucei); a 208-TGAG for 208-YGGS loop

28 everal African trypanosome species including Trypanosoma brucei brucei, but not the human-infective p

29 een of approximately 87000 compounds against Trypanosoma brucei brucei, we recently identified eight

30 Trypanosoma brucei causes African sleeping sickness for

31 Trypanosoma brucei causes African trypanosomiasis and co

32 Trypanosoma brucei causes fatal human African trypanosom

33 The protist parasite Trypanosoma brucei causes Human African trypanosomiasis

34 Trypanosoma brucei causes human African trypanosomiasis

35 Trypanosoma brucei causes human African trypanosomiasis

36 Trypanosoma brucei causes human African trypanosomiasis

37 The protozoan parasite Trypanosoma brucei causes the fatal illness human Africa

38 A defining feature of Trypanosoma brucei cell shape is the lateral attachment

39 red the transcriptomes of cultured procyclic Trypanosoma brucei cells in early and late logarithmic p

40 also showed high inhibitory potency against Trypanosoma brucei cultures.

41 Survival of Trypanosoma brucei depends upon switches in its protecti

42 The human parasite Trypanosoma brucei does not synthesize heme de novo and

43 generates functional mitochondrial mRNAs in Trypanosoma brucei Editing is catalyzed by three distinc

44 Trypanosoma brucei encodes three paralogue single-protei

45 Unlike other type II TKs, the Trypanosoma brucei enzyme (TbTK) is a tandem protein wit

46 Trypanosoma brucei evades the host immune system through

47 screens were undertaken in bloodstream form Trypanosoma brucei exposed to the antifolates methotrexa

48 Trypanosoma brucei expresses a diverse repertoire of N-g

49 However, Trypanosoma brucei expresses an unusual CPC consisting o

50 The bloodstream form of the human pathogen Trypanosoma brucei expresses oligomannose, paucimannose,

51 Trypanosoma brucei faces relentless immune attack in the

52 We sought to develop inhibitors of Trypanosoma brucei FolD (TbFolD) as potential antiparasi

53 ine reductase 1 with phenotypic screening on Trypanosoma brucei for hit identification.

54 tivity against either human FPPS (HsFPPS) or Trypanosoma brucei FPPS (TbFPPS), the most active being

55 amides have been identified as inhibitors of Trypanosoma brucei from screening of a focused protease

56 uman African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense can be diagnosed in the ear

57 Infection rates of Trypanosoma brucei gambiense in tsetse are extremely low

58 to replace the current treatment regimen for Trypanosoma brucei gambiense infections, following a pos

59 this effect in an important human pathogen, Trypanosoma brucei gambiense.

60 e of Human African Trypanosomiasis caused by Trypanosoma brucei gambiense.

61 on of both alleles of JGT from the genome of Trypanosoma brucei generates a cell line that completely

62 The Trypanosoma brucei genome contains more than 1,000 VSG g

63 However, the Trypanosoma brucei genome encodes only the last two step

64 l evaluation of aminopyrazole derivatives as Trypanosoma brucei GSK3 short inhibitors.

65 In contrast to most other eukaryotes Trypanosoma brucei has a single mitochondrion whose sing

66 In this study, we report the structure of Trypanosoma brucei HpHbR in complex with human haptoglob

67 ausative agent of African sleeping sickness, Trypanosoma brucei In mitochondria of this pathogen, mos

68 The life cycle of Trypanosoma brucei involves developmental transitions th

69 Trypanosoma brucei is a protozoan parasite that evades i

70 The African trypanosome Trypanosoma brucei is a single-celled eukaryote with a s

71 Trypanosoma brucei is a vector borne, lethal protistan p

72 Trypanosoma brucei is an extracellular parasite that cau

73 Trypanosoma brucei is the causative agent of African sle

74 The parasite Trypanosoma brucei is the causative agent of African sle

75 The eukaryotic protozoan parasite Trypanosoma brucei is the causative agent of human Afric

76 The mitochondrion of the parasitic protozoan Trypanosoma brucei lacks tRNA genes, and thus imports al

77 screen with 176 individual bloodstream form Trypanosoma brucei lines identified PKs required for pro

78 Trypanosoma brucei N-myristoyltransferase (TbNMT) is an

79 The Polo-like kinase (PLK) in Trypanosoma brucei plays multiple roles in basal body se

80 Trypanosoma brucei PRMT7 (TbPRMT7) is a protein arginine

81 on of the potentials of the redox centers in Trypanosoma brucei QSOX provides a context for understan

82 The infectious metacyclic forms of Trypanosoma brucei result from a complex development in

83 ition of the cysteine proteases rhodesain of Trypanosoma brucei rhodesiense and falcipain-2 of Plasmo

84 .045 muM against the human pathogenic strain Trypanosoma brucei rhodesiense and is more than 4000 tim

85 tent inhibitory effect against the parasites Trypanosoma brucei rhodesiense and Leishmania donovani w

86 r proteins that contribute to virulence, and Trypanosoma brucei rhodesiense EVs contain the serum res

87 stance to most African trypanosomes, but not Trypanosoma brucei rhodesiense or T.b. gambiense, which

88 layed in vitro nanomolar IC50 values against Trypanosoma brucei rhodesiense STIB900 with selectivity

89 ural product displayed high activity against Trypanosoma brucei rhodesiense, a recalcitrant parasite

90 ch as Plasmodium falciparum, Lassa Virus and Trypanosoma brucei rhodesiense, has resulted in elevated

91 ave additional trypanolytic activity against Trypanosoma brucei rhodesiense, the cause of acute Afric

92 orrelation with the human infective parasite Trypanosoma brucei rhodesiense, the most potent compound

93 st important human trypanosomatid pathogens (Trypanosoma brucei rhodesiense, Trypanosoma cruzi, and L

94 c markers in CSF from patients infected with Trypanosoma brucei rhodesiense, using 1H nuclear magneti

95 ite concentrations in patients infected with Trypanosoma brucei rhodesiense, using liquid chromatogra

96 We report X-ray structures of Trypanosoma brucei S-adenosylmethionine decarboxylase al

97 ved following RNAi-mediated silencing of the Trypanosoma brucei SODA ortholog suggests that SODA is e

98 The protozoan parasites Trypanosoma brucei spp. cause important human and livest

99 sites Trypanosoma cruzi, Leishmania spp. and Trypanosoma brucei spp., respectively.

100 the procyclic and bloodstream form stages of Trypanosoma brucei that yields viable and proliferative

101 ing the cell cycle of the protozoan parasite Trypanosoma brucei The source of components required to

102 ow that cytosine 32 in the anticodon loop of Trypanosoma brucei tRNA(Thr) is methylated to 3-methylcy

103 Mitochondrial mRNAs in Trypanosoma brucei undergo extensive insertion and delet

104 ghly motile and versatile protozoan pathogen Trypanosoma brucei undergoes a complex life cycle in the

105 Trypanosoma brucei undergoes cytokinesis uni-directional

106 Trypanosoma brucei uses multiple mechanisms to evade det

107 nhibited J synthesis in Leishmania major and Trypanosoma brucei using DMOG.

108 ve-site residues of PRMT7 from the protozoan Trypanosoma brucei We have designed 26 single and double

109 ulation of glycosomes in live procyclic form Trypanosoma brucei When added to cells, this fluorescent

110 Compound 64 cured mice infected with Trypanosoma brucei when dosed orally down to 2.5 mg/kg.

111 component of approximately 20S editosomes in Trypanosoma brucei which contains a degenerate, noncatal

112 idal activity against the protozoan parasite Trypanosoma brucei with IC50 < 5 muM, being each of thos

113 bitor of proliferation for the HAT pathogen (Trypanosoma brucei), we have now tested this class of an

114 tozoa (Leishmania spp., Plasmodium spp., and Trypanosoma brucei).

115 Trypanosoma brucei, a causative agent of African Sleepin

116 We examined BBSome functions in Trypanosoma brucei, a flagellated protozoan parasite tha

117 rganisms belonging to the phylum euglenozoa: Trypanosoma brucei, a lethal human parasite, and Euglena

118 Trypanosoma brucei, a lethal parasite living in the huma

119 and condition-specific metabolic network of Trypanosoma brucei, a parasitic protozoan responsible fo

120 In Trypanosoma brucei, an ancient unicellular eukaryote, on

121 e biosynthesis pathway of the human parasite Trypanosoma brucei, an early branching eukaryote that la

122 y a pivotal role in life-cycle regulation of Trypanosoma brucei, as the translocation of a protein ph

123 ishmania displays striking conservation with Trypanosoma brucei, despite the latter parasite replicat

124 However, in Trypanosoma brucei, disorganized arrays of microtubules

125 ential for growth of the parasitic protozoan Trypanosoma brucei, enabling the study of its function i

126 microbes, such as the kinetoplastid parasite Trypanosoma brucei, have a defined size, shape, and form

127 insect salivary glands for all subspecies of Trypanosoma brucei, including the human pathogens.

128 ed to TbKHC1, an orphan kinesin H chain from Trypanosoma brucei, inhibited T. musculi excreted/secret

129 The African trypanosome, Trypanosoma brucei, is a parasitic protozoan that achiev

130 receptor of the African trypanosome species, Trypanosoma brucei, is expressed when the parasite is in

131 OM protein of the early diverging protozoan Trypanosoma brucei, is signal-anchored.

132 tive agent of human African trypanosomiasis, Trypanosoma brucei, lacks de novo purine biosynthesis an

133 In Trypanosoma brucei, most mitochondrial mRNAs undergo int

134 In Trypanosoma brucei, PE synthesis has been shown to occur

135 Trypanosoma brucei, protozoan parasites that cause human

136 t that CRK1, a G1 cyclin-dependent kinase in Trypanosoma brucei, regulates anterograde protein traffi

137 ains of TR from the basal eukaryotic species Trypanosoma brucei, revealing the ancestry of TR compris

138 e SAS-4 homolog in the flagellated protozoan Trypanosoma brucei, TbSAS-4, plays an unusual role in co

139 ruzi, the causative agent of Chagas disease; Trypanosoma brucei, the causative agent of African sleep

140 Trypanosoma brucei, the causative agent of African sleep

141 Lipid metabolism in Trypanosoma brucei, the causative agent of African sleep

142 Here, we report that Trypanosoma brucei, the causative agent of African trypa

143 Trypanosoma brucei, the causative agent of human African

144 , which had been identified as a hit against Trypanosoma brucei, the causative agent of human African

145 mpound library for antiparasitic activity on Trypanosoma brucei, the causative agent of human African

146 es (PKs) are a class of druggable targets in Trypanosoma brucei, the causative agent of Human African

147 Here, we show that Trypanosoma brucei, the causative agent of human sleepin

148 Trypanosoma brucei, the causative agent of sleeping sick

149 In Trypanosoma brucei, the composition of the gamma-tubulin

150 Trypanosoma brucei, the etiologic agent of African Sleep

151 In the case of Trypanosoma brucei, the etiological agent of African try

152 A recent genome-wide analysis of Trypanosoma brucei, the etiological agent of sleeping si

153 In Trypanosoma brucei, the vast majority of gRNAs are trans

154 In Trypanosoma brucei, three of the five centrins associate

155 e diseases caused by the protozoan parasites Trypanosoma brucei, Trypanosoma cruzi, and Leishmania sp

156 nt parasites and include the human pathogens Trypanosoma brucei, Trypanosoma cruzi, and Leishmania sp

157 wth, and infectivity of the trypanosomatids: Trypanosoma brucei, Trypanosoma cruzi, and Leishmania.

158 pathway and its enzymes have been studied in Trypanosoma brucei, Trypanosoma cruzi, and various Leish

159 In the protist Trypanosoma brucei, two distinct genes encode fairly dif

160 its application to the pathogenic protozoan, Trypanosoma brucei, using hyperpolarized (13)C1 pyruvate

161 In the unicellular parasite Trypanosoma brucei, which causes African sleeping sickne

162 The protozoan parasite Trypanosoma brucei, which causes devastating diseases in

163 An example is Trypanosoma brucei, which causes human African trypanoso

164 in the causative agent of sleeping sickness, Trypanosoma brucei, with that of human erythrocytes, and

165 ke and the modulation of drug sensitivity in Trypanosoma brucei.

166 by RNA polymerase I (Pol I) in the parasite Trypanosoma brucei.

167 diting in kinetoplastid protists typified by Trypanosoma brucei.

168 ents in the large ribosomal subunit (60S) of Trypanosoma brucei.

169 e boundaries of previously annotated CDSs in Trypanosoma brucei.

170 As and is unique for kinetoplastids, such as Trypanosoma brucei.

171 generates functional mitochondrial mRNAs in Trypanosoma brucei.

172 telomeric ESs and VSG antigenic switching in Trypanosoma brucei.

173 characterize the non-snRNP PRP19 complex of Trypanosoma brucei.

174 and the early diverging parasitic protozoan, Trypanosoma brucei.

175 lar activity against the bloodstream form of Trypanosoma brucei.

176 all lysine residues for all core histones of Trypanosoma brucei.

177 ut not CD8(+), T cells in mice infected with Trypanosoma brucei.

178 . Leishmania donovani, Trypanosoma cruzi and Trypanosoma brucei.

179 ganisation of transcription in the genome of Trypanosoma brucei.

180 essential for retrograde cargo transport in Trypanosoma brucei.

181 ,3-d]pyrimidines are inhibitors of PTR1 from Trypanosoma brucei.

182 tion of 19 kinetochore proteins (KKT1-19) in Trypanosoma brucei.

183 cycle, and development in the model parasite Trypanosoma brucei.

184 glycoprotein (VSG) expression sites (ESs) of Trypanosoma brucei.

185 in tRNAs from Bacillus subtilis, plants and Trypanosoma brucei.

186 orthologue, PNT1, in the parasitic protozoon Trypanosoma brucei.

187 ositol pyrophosphate biosynthetic pathway in Trypanosoma brucei: inositol polyphosphate multikinase (

188 of unicellular parasitic flagellate protozoa.Trypanosoma bruceispecies and Trypanosoma cruziare the m

189 We report a way to selectively kill Trypanosoma by blocking glycosomal/peroxisomal import th

190 o-infections with other trypanosome species (Trypanosoma congolense and Trypanosoma vivax) are common

191 mal African trypanosomiasis (AAT), caused by Trypanosoma congolense and Trypanosoma vivax, remains on

192 Here we show that in Trypanosoma congolense this receptor is instead expresse

193 Trypanosoma cruzi (T. cruzi) infection is endemic in Lat

194 hibitors of the carbonic anhydrase (CA) from Trypanosoma cruzi (TcCA).

195 vector-borne pathogens, with the example of Trypanosoma cruzi (the etiological agent of Chagas disea

196 the authors present a 2.5-A structure of the Trypanosoma cruzi 60S ribosomal subunit and propose a mo

197 re than 20 outstanding derivatives with anti-Trypanosoma cruzi activity.

198 disease is caused by the protozoan parasite Trypanosoma cruzi and affects 5-8 million people in Lati

199 Chagas disease is caused by the parasite Trypanosoma cruzi and is an important cause of morbidity

200 have been considered as virulence factors of Trypanosoma cruzi and Leishmania spp., and have been dem

201 e is a chronic infection in humans caused by Trypanosoma cruzi and manifested in progressive cardiomy

202 to human disease, i.e. Leishmania donovani, Trypanosoma cruzi and Trypanosoma brucei.

203 The Trypanosoma cruzi ascorbate peroxidase is, by sequence a

204 ole and posaconazole have not been tested in Trypanosoma cruzi carriers.

205 Trypanosoma cruzi causes American trypanosomiasis, where

206 The Chagas' disease parasite Trypanosoma cruzi elicits a potent inflammatory response

207 The genome of the parasite Trypanosoma cruzi encodes two copies of autophagy-relate

208 e extreme genetic diversity of the protozoan Trypanosoma cruzi has been proposed to be associated wit

209 Oral transmission of Trypanosoma cruzi has gained relevance because of its as

210 at immune responses in subjects with chronic Trypanosoma cruzi infection display features common to o

211 Trypanosoma cruzi infection drives the expansion of rema

212 Increasingly during the past few decades, Trypanosoma cruzi infection has been detected in North A

213 city and equivalent or improved efficacy for Trypanosoma cruzi infection is a priority.

214 loss of certain functional activities during Trypanosoma cruzi infection might result in the inabilit

215 nic Chagas disease cardiomyopathy, caused by Trypanosoma cruzi infection, is a major cause of heart f

216 Trypanosoma cruzi infection, which is the etiological ag

217 eviously described in immune response during Trypanosoma cruzi infection.

218 ine protease cruzipain (Cz) protects against Trypanosoma cruzi infection.

219 uestions in detail using the murine model of Trypanosoma cruzi infection.

220 afety of benznidazole in adults with chronic Trypanosoma cruzi infection.

221 o be relevant in the context of experimental Trypanosoma cruzi infection.

222 In chronic Trypanosoma cruzi infections, parasite burden is control

223 Chagas disease caused by Trypanosoma cruzi is a paradigmatic example of a chronic

224 The insect-transmitted protozoan parasite Trypanosoma cruzi is the causative agent of Chagas disea

225 Trypanosoma cruzi is the causative agent of chronic chag

226 Trypanosoma cruzi is the etiologic agent of Chagas disea

227 Trypanosoma cruzi is the etiological agent of Chagas dis

228 are highly conserved in clinically relevant Trypanosoma cruzi isolates and are recognized by B and T

229 896 patients; 60.5% had positive results for Trypanosoma cruzi on PCR.

230 no significant activity was detected against Trypanosoma cruzi or Leishmania donovani.

231 Chagas disease, caused by Trypanosoma cruzi parasite, was described thousands of y

232 Trypanosoma cruzi parasites are the causative agents of

233 es, we determined the 2.5-A structure of the Trypanosoma cruzi ribosome large subunit by single-parti

234 Trypanosoma cruzi species is categorized into six discre

235 Trypanosoma cruzi trans-sialidase (TcTS) is a key target

236 Congenital Trypanosoma cruzi transmission is now estimated to accou

237 pest insect that has the ability to transmit Trypanosoma cruzi under experimental laboratory conditio

238 Serological testing for Trypanosoma cruzi was performed at enrollment.

239 ureus), a virus (influenza), and a parasite (Trypanosoma cruzi).

240 potentially foodborne parasites (for example Trypanosoma cruzi).

241 Chagas disease is caused by the protozoan Trypanosoma cruzi, affecting millions of people worldwid

242 as disease, caused by the protozoan parasite Trypanosoma cruzi, affects 7 million people in Latin Ame

243 gas disease is a chronic infection caused by Trypanosoma cruzi, an intracellular protozoan parasite.

244 disease is caused by the protozoan parasite Trypanosoma cruzi, and activation of CD8(+) T cells is c

245 d pathogens (Trypanosoma brucei rhodesiense, Trypanosoma cruzi, and Leishmania donovani), and two com

246 infections due to Toxoplasma gondii (n = 3), Trypanosoma cruzi, and Leishmania species.

247 the protozoan parasites Trypanosoma brucei, Trypanosoma cruzi, and Leishmania spp.

248 lude the human pathogens Trypanosoma brucei, Trypanosoma cruzi, and Leishmania spp., which in humans

249 of the trypanosomatids: Trypanosoma brucei, Trypanosoma cruzi, and Leishmania.

250 mes have been studied in Trypanosoma brucei, Trypanosoma cruzi, and various Leishmania species.

251 ng infection with the intracellular parasite Trypanosoma cruzi, as evidenced by transcriptome and cyt

252 rom the parasite that causes Chagas disease, Trypanosoma cruzi, directly in whole, unprocessed human

253 sed by infection with the protozoan parasite Trypanosoma cruzi, is a leading cause of heart disease (

254 Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and affec

255 Chagas disease, caused by the parasite Trypanosoma cruzi, is endemic in Latin America.

256 s' disease, caused by the protozoan parasite Trypanosoma cruzi, is the most common cause of cardiac-r

257 y infection with the kinetoplastid parasites Trypanosoma cruzi, Leishmania spp. and Trypanosoma bruce

258 a novel mechanism used by diverse pathogens (Trypanosoma cruzi, Listeria monocytogenes, and adenoviru

259 mice with the myotropic Colombiana strain of Trypanosoma cruzi, parasites persisted in tissue at low

260 and virulence of Trypanosoma brucei and, in Trypanosoma cruzi, PDEC2 was shown to be required for no

261 uM against neglected Chagas' disease causing Trypanosoma cruzi, respectively.

262 bound to a distinctive Argonaute protein of Trypanosoma cruzi, TcPIWI-tryp.

263 Using a murine model of infection with Trypanosoma cruzi, the causal agent of Chagas cardiomyop

264 lled intestinal microbiota, neither affected Trypanosoma cruzi, the causal agent of Chagas disease, i

265 ted with AT during part of their life cycle: Trypanosoma cruzi, the causative agent of Chagas disease

266 Trypanosoma cruzi, the causative agent of Chagas disease

267 gi, and more recently the protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease

268 The release of EVs by Trypanosoma cruzi, the causative agent of Chagas disease

269 (NMT), an essential and druggable target in Trypanosoma cruzi, the causative agent of Chagas' diseas

270 Trypanosoma cruzi, the causing agent of Chagas disease,

271 Methods for genetic manipulation of Trypanosoma cruzi, the etiologic agent of Chagas disease

272 of the contractile vacuole complex (CVC) of Trypanosoma cruzi, the etiologic agent of Chagas disease

273 critical events throughout the life cycle of Trypanosoma cruzi, the etiological agent of Chagas disea

274 Trypanosoma cruzi, the etiological agent of Chagas disea

275 ves that inhibit TIM's catalytic activity in Trypanosoma cruzi, the parasite that causes Chagas disea

276 elivers Gzms into three protozoan parasites (Trypanosoma cruzi, Toxoplasma gondii and Leishmania majo

277 disease is caused by the protozoan parasite Trypanosoma cruzi, which depends on the production of en

278 ar why only a proportion of children born to Trypanosoma cruzi-infected mothers acquire the infection

279 ongenital transmission and cardiomyopathy in Trypanosoma cruzi-infected women.

280 hmania-like flagellum attachment zone, and a Trypanosoma cruzi-like cytostome are ancestral features,

281 in the activation and functional profile of Trypanosoma cruzi-specific DN T cells.

282 viduals infected with the protozoan parasite Trypanosoma cruzi.

283 mmunity following intradermal infection with Trypanosoma cruzi.

284 ection caused by the intracellular protozoan Trypanosoma cruzi.

285 CI 2.2-6.8) were estimated to be infected by Trypanosoma cruzi.

286 the kinetoplastidea including Leishmania and Trypanosoma cruzi.

287 used by the kinetoplastid protozoan parasite Trypanosoma cruzi.

288 idate clathrin-associated proteins (CAPs) in Trypanosoma cruzi; the cohort includes orthologs of many

289 llate protozoa.Trypanosoma bruceispecies and Trypanosoma cruziare the major agents of human trypanoso

290 The causative parasite, Trypanosoma, encodes soluble versions of inorganic pyrop

291 testing identified the infecting species as Trypanosoma evansi.Despite relapsing 6 weeks after compl

292 The parasitic protists of the Trypanosoma genus infect humans and domestic mammals, ca

293 o enrich different cell types, concentrating Trypanosoma in blood at very low levels of infection, on

294 hosts) trypanosomatid species of the genera Trypanosoma, Leishmania, and Phytomonas, but only fragme

295 examination of blood revealed infection with Trypanosoma METHODS: Microscopic observation, polymerase

296 ced in macrophages during mouse infection by Trypanosoma musculi, a natural parasite of this host.

297 , an enzyme that reduces dihydrobiopterin in Trypanosoma spp., has been identified as a candidate tar

298 identify PEX14 as an "Achilles' heel" of the Trypanosoma suitable for the development of new therapie

299 panosome species (Trypanosoma congolense and Trypanosoma vivax) are common in animals, generating the

300 (AAT), caused by Trypanosoma congolense and Trypanosoma vivax, remains one of the most important liv