ライフサイエンスコーパス: U. urealyticum

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1 U. urealyticum alone and in combination with LPS induced

2 U. urealyticum can be divided into two biovars comprisin

3 U. urealyticum has six closely related iron transporters

4 U. urealyticum was detected in 85 (41.1%) women.

5 U. urealyticum was identified in 29 subjects (11.4%).

6 U. urealyticum was not associated with NGU.

7 U. urealyticum-positive women also had a higher prevalen

8 alyticum-positive women compared with only 1 U. urealyticum-negative woman (0.4%) (P<.0001).

9 Preterm birth was documented in 7 (24.1%) U. urealyticum-positive women compared with only 1 U. ur

10 A subsequent preterm labor occurred in 17 U. urealyticum-positive women (58.6%), compared with 10

11 itive women (58.6%), compared with 10 (4.4%) U. urealyticum-negative women (P<.0001).

12 The relationship between intra-amniotic U. urealyticum in healthy second-trimester pregnant wome

13 and discrimination of Ureaplasma parvum and U. urealyticum and their 14 serovars by real-time PCR.

14 After stimulation with U. parvum and U. urealyticum, the expression of cell defense genes, in

15 , were cocultured with Ureaplasma parvum and U. urealyticum.

16 IL-6, and IL-10 in vitro by unstimulated and U. urealyticum (with or without lipopolysaccharide [LPS]

17 acterial enzymes appear not to be encoded by U. urealyticum, including the cell-division protein FtsZ

18 10(-2) CFU/microl PCR mixture for detecting U. urealyticum.

19 by enzyme-linked immunosorbent assay and for U. urealyticum and IL-1ra genotypes by PCR.

20 sting of second-trimester amniotic fluid for U. urealyticum can identify women at risk for subsequent

21 ra level was 450 ng/ml in women positive for U. urealyticum, as opposed to 225 ng/ml in women negativ

22 In preterm cells, high-inoculum U. urealyticum (10(6) CCU) (i) stimulated TNF-alpha and

23 High-inoculum U. urealyticum (i) stimulated release of all four cytoki

24 In vitro inoculation with low-inoculum U. urealyticum (10(3) color-changing units [CCU]) (i) pa

25 TNF-alpha in response to challenge with LPS, U. urealyticum, and M. hominis in a concentration-depend

26 The IL-1ra genotype or U. urealyticum colonization was unrelated to birth weigh

27 on in a dose-dependent manner but suppressed U. urealyticum-mediated TNF-alpha production only at the

28 U. parvum was detected more often than U. urealyticum.

29 We hypothesized that U. urealyticum alters the host immune response in the pr

30 We speculate that U. urealyticum enhances the proinflammatory response to

31 Although the U. urealyticum genome is similar to the two sequenced my

32 Among the 31 women with vaginal U. urealyticum, only 3 (9.7%) were homozygous for allele

33 preterm infants for Ureaplasma parvum versus U. urealyticum.

34 lationship between vaginal colonization with U. urealyticum, vaginal interleukin-1 receptor antagonis

35 Pregnant women who are colonized with U. urealyticum during the first trimester have elevated

36 e IL-1ra gene (IL-1RN*2) were colonized with U. urealyticum, as opposed to 47% of the 49 women who we

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