ライフサイエンスコーパス: U6 snRNP

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1 train increases the levels of both Lsm8p and U6 snRNPs.

2 site, Hu proteins prevent binding of U1 and U6 snRNPs to the 5' splice site, while TIAR increases bi

3 base-pairing, and the release of free U4 and U6 snRNPs.

4 off" the 5' splice site region to the U5 and U6 snRNPs before splicing begins.

5 in seems to be critical for retaining U5 and U6 snRNPs during/after spliceosomal activation through i

6 s in equal stoichiometry with U2, U4, U5 and U6 snRNPs; however, its abundance in human far exceeds t

7 ein Prp43p is the removal of the U2, U5, and U6 snRNPs from the postsplicing lariat-intron ribonucleo

8 the tandem 5' splice sites being mediated by U6 snRNP, rather than U1 snRNP.

9 ortance of U1 snRNP and, to a lesser extent, U6 snRNP in differentially recognizing wild-type versus

10 proposed role as a chaperone in facilitating U6 snRNP assembly.

11 We propose a model for U6 snRNP assembly that explains how evolutionarily diver

12 t U6 snRNP in vitro, and propose a model for U6 snRNP assembly.

13 as1p causes a reduction in the level of free U6 snRNP.

14 mature U6 snRNP, consistent with a defect in U6 snRNP assembly.

15 ave drastically reduced levels of the mature U6 snRNP, consistent with a defect in U6 snRNP assembly.

16 pliceosomal snRNPs, the Lsm proteins mediate U6 snRNP localization except that nuclear retention is t

17 d U6 snRNA strongly suggests a novel role of U6 snRNP in regulated alternative RNA processing.

18 nonical core Sm proteins, there are a set of U6 snRNP specific Sm proteins, eight previously describe

19 s a key component in the very early steps of U6 snRNP assembly.

20 g of RNA structure that is chaperoned by the U6 snRNP protein Prp24.

21 ar retention is the likely mechanism for the U6 snRNP.

22 us facilitating assembly of the RNA into the U6 snRNP.

23 itating conformational rearrangements of the U6 snRNP in the association-dissociation cycle of splice

24 at SMN also functions in the assembly of the U6 snRNP in the nucleus and in the assembly of other Lsm

25 ectively, these data identify domains of the U6 snRNP that are critical for one of the first steps in

26 ified a mutation in a novel component of the U6 snRNP that causes yeast cells to require Lhp1p for gr

27 release from pre-rRNA and production of the U6 snRNP.

28 required for switching the U1 snRNP with the U6 snRNP at the precursor mRNA (pre-mRNA) 5' splice site

29 mplexes (designated B(028)) revealed that U4/U6 snRNP proteins are released during activation before

30 binding, thus assisting formation of the U4/U6 snRNP.

31 purified Prp24 protein regenerates duplex U4/U6 snRNPs for new rounds of splicing.

32 becomes essential for the accumulation of U4/U6 snRNPs and for cell viability.

33 , that interconverts free and base-paired U4/U6 snRNPs.

34 r localization of U6 is independent from [U4/U6] snRNP formation since sites of direct interaction of

35 itute post-transcriptional assembly of yeast U6 snRNP in vitro, and propose a model for U6 snRNP asse

36 e the post-transcriptional assembly of yeast U6 snRNP in vitro, which occurs through a complex series

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