ライフサイエンスコーパス: UDP glucuronic acid

1 cal polymer from UDP-N-acetylglucosamine and UDP-glucuronic acid.

2 nal UDP-glycosyltransferase UGT co-substrate UDP-glucuronic acid.

3 ), UDP-N-acetylglucosamine (UDP-GlcNAc), and UDP-glucuronic acid.

4 lyzes two oxidations of UDP-glucose to yield UDP-glucuronic acid.

5 ntermediate that is synthesized by ArnA from UDP-glucuronic acid.

6 pose a pathway for l-Ara4N biosynthesis from UDP-glucuronic acid.

7 combinant UAS homologs all form UDP-Api from UDP-glucuronic acid albeit in different amounts.

8 Mutations in a previously identified UDP-glucuronic acid allosteric binding site decreased th

9 ities for the sugar donors UDP-galactose and UDP-glucuronic acid, although UDP-glucose was always pre

10 uccessive oxidations of UDP-glucose to yield UDP-glucuronic acid, an essential precursor for matrix p

11 UDP-glucose dehydrogenase (Ugd) generates UDP-glucuronic acid, an important precursor for the prod

12 copyranosiduronic acids (glucuronides) using UDP-glucuronic acid and acceptor substrates such as drug

13 (+)-dependent oxidation of the 4''-OH of the UDP-glucuronic acid and decarboxylation of the UDP-4-ket

14 rt to its ability to sequester intracellular UDP-glucuronic acid and inhibition of hyaluronan synthas

15 showed that the resulting mutant lacked both UDP-glucuronic acid and its downstream product, UDP-xylo

16 ponsible for the oxidation of UDP-glucose to UDP-glucuronic acid and its subsequent decarboxylation t

17 y, we propose a binding model for NAD(+) and UDP-glucuronic acid and the involvement of residues T(43

18 UXNAcS is specific and cannot utilize UDP-glucuronic acid and UDP-galacturonic acid as substra

19 s that synthesize the building blocks of HA, UDP-Glucuronic acid and UDP-N-Acetyl-Glucosamine, as wel

20 HA synthases (HAS1-3), which use cytoplasmic UDP-glucuronic acid and UDP-N-acetylglucosamine as subst

21 rategy, we used purified S. equisimilis HAS, UDP-glucuronic acid, and UDP[beta-32P]-Glc-NAc to radiol

22 The UGT1 and UGT2 enzymes use UDP-glucuronic acid, and UGT3 enzymes use UDP-N-acetylgl

23 oded by the ORF atu2297, with UDP-glucose or UDP-glucuronic acid as sugar donors.

24 .8-A resolution apo crystal structure of the UDP-glucuronic acid binding domain of human UGT isoform

25 he encoded protein is closely related to the UDP-glucuronic acid binding site consensus sequence, and

26 Biosynthesis of UDP-glucuronic acid by UDP-glucose 6-dehydrogenase (UGDH

27 2 nM) enhanced the potency of UDPG (but not UDP-glucuronic acid) by 7-fold.

28 s at residues predicted to interact with the UDP-glucuronic acid cofactor exhibited significantly imp

29 n the content of UDP-N-acetylhexosamines and UDP-glucuronic acid, correlating with the expression lev

30 acid (UDP-GlcA) is irreversibly catalyzed by UDP-glucuronic acid decarboxylase (UXS).

31 Biosynthesis of UDP-xylose is mediated by UDP-glucuronic acid decarboxylase, which converts UDP-gl

32 II transmembrane protein that functions as a UDP-glucuronic acid decarboxylase.

33 yptococcal sequence as putatively encoding a UDP-glucuronic acid decarboxylase.

34 m adenosine diphosphate-activated platelets, UDP-glucuronic acid-dependent bilirubin conjugation was

35 We demonstrated that lpsL encoded a UDP-glucuronic acid epimerase activity that was reduced

36 psL, a gene previously predicted to encode a UDP-glucuronic acid epimerase.

37 d C-4" oxidation and C-6" decarboxylation of UDP-glucuronic acid, followed by the C-4" transamination

38 ion and C-6" decarboxylation of [alpha-(32)P]UDP-glucuronic acid, followed by transamination to gener

39 Extracts of the mutants completely lacked UDP-glucuronic acid:Galbeta1,3Gal-R glucuronosyltransfer

40 AS) is a membrane-bound enzyme that utilizes UDP-glucuronic acid (GlcUA) and UDP-GlcNAc to synthesize

41 ae catalyzes sugar transfer from UDP-Glc and UDP-glucuronic acid (GlcUA) to a polymer with the repeat

42 The oxidative decarboxylation of UDP-glucuronic acid is catalyzed by the 345-residue C-te

43 In mammalian organisms, UDP-glucuronic acid is typically used in the transfer re

44 gar residues in the capsule are derived from UDP-glucuronic acid or its metabolites.

45 We propose that the regulation of UDP-glucuronic acid production in a specific subset of v

46 and indicating that an alternate pathway for UDP-glucuronic acid production was not used.

47 capI(Ssp) show homology to genes involved in UDP-glucuronic acid synthesis.

48 ponents may be linked to the availability of UDP-glucuronic acid; therefore UGDH is an intriguing the

49 micals by linking glucuronic acid donated by UDP-glucuronic acid to a lipophilic acceptor substrate.

50 n encoded by PsUGT1 catalyzes conjugation of UDP-glucuronic acid to an unknown compound.

51 e unprecedented oxidative decarboxylation of UDP-glucuronic acid to form uridine 5'-(beta-l-threo-pen

52 AD(+)-dependent oxidative decarboxylation of UDP-glucuronic acid to generate a UDP-4'-keto-pentose su

53 (i) the NAD(+)-dependent decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and (ii) the

54 One activity is to decarboxylate UDP-glucuronic acid to UDP-beta-l-threo-pentopyranosyl-4

55 e C. neoformans gene catalyzed conversion of UDP-glucuronic acid to UDP-xylose, as confirmed by NMR a

56 lucuronic acid decarboxylase, which converts UDP-glucuronic acid to UDP-xylose.

57 NAD+-dependent oxidative decarboxylation of UDP-glucuronic acid to yield the UDP-4''-ketopentose, ur

58 y the authentic sugar nucleotide precursors, UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylglucosami

59 Api) together with UDP-xylose is formed from UDP-glucuronic acid (UDP-GlcA) by UDP-Api synthase (UAS)

60 The biosynthesis of UDP-Xyl from UDP-glucuronic acid (UDP-GlcA) is irreversibly catalyzed

61 UDP-glucuronic acid (UDP-GlcA) is the precursor of many

62 alyzing (1) the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcA) to the UDP-4' '-ketopento

63 and is synthesized by the decarboxylation of UDP-glucuronic acid (UDP-GlcA).

64 sphate (Glc-6-P) --> Glc-1-P --> UDP-Glc --> UDP-glucuronic acid (UDP-GlcUA) --> (GlcUA-Glc)(n).

65 disaccharide units from the donor molecules UDP-glucuronic acid (UDP-GlcUA) and UDP-N-acetylglucosam

66 neumoniae requires UDP-glucose (UDP-Glc) and UDP-glucuronic acid (UDP-GlcUA) for production of the [3

67 he presence of protein-mediated transport of UDP-glucuronic acid (UDP-GlcUA) in rat liver endoplasmic

68 -d-GlcUA-(1-] from UDP-glucose (UDP-Glc) and UDP-glucuronic acid (UDP-GlcUA) is catalysed by the type

69 substrate for all glucuronidation reactions, UDP-glucuronic acid (UDP-GlcUA), was determined using a

70 yces cerevisiae expressing SQV-7 transported UDP-glucuronic acid, UDP-N-acetylgalactosamine, and UDP-

71 HA synthase for UDP-N-acetylglucosamine and UDP-glucuronic acid were estimated to be approximately 7

72 y catalyzes the conversion of UDP-glucose to UDP-glucuronic acid, which is essential for the biosynth