ライフサイエンスコーパス: UIP

1 traction bronchiectasis, honeycombing, and a UIP pattern than those with nonfibrotic HP (P = .015, P

2 and lower zone predominance was considered a UIP pattern.

3 Pflex (Cstart), compliance between Pflex and UIP (Cinf), and compliance between UIP and peak pressure

4 Pflex and UIP (Cinf), and compliance between UIP and peak pressure (Cend) for the inflation limb, and

5 ance associated with the distinction between UIP and fibrotic NSIP.

6 or patients with NSIP than for those in both UIP groups (p < 0.001), although survival in the two UIP

7 ificantly increased the synthesis of CCL7 by UIP fibroblasts.

8 mparisons), with more fibrosis in concordant UIP (2.13 +/- 0.62) than in discordant UIP (1.42 +/- 0.7

9 se trials represented patients with definite UIP and a large subgroup of patients with possible UIP.

10 rdant UIP (2.13 +/- 0.62) than in discordant UIP (1.42 +/- 0.73), fibrotic NSIP (0.83 +/- 0.58), or c

11 all lobes were categorized as concordant for UIP (n = 51) and those with UIP in at least one lobe wer

12 Patients concordant for UIP were older (63 +/- 9 [mean +/- SD] yr; p < 0.05 as c

13 all other groups) than those discordant for UIP (57 +/- 12 yr) or with fibrotic NSIP (56 +/- 11 yr)

14 one lobe were categorized as discordant for UIP (n = 28).

15 P in any lobe should be classified as having UIP.

16 However, UIP, PMC, Cinf, and Cdef increased as the PIP increased.

17 cal clinical and HRCT features of idiopathic UIP, neither prednisone nor colchicine resulted in objec

18 hic usual interstitial pneumonia (idiopathic UIP) were entered into a randomized prospective treatmen

19 historical control subjects with idiopathic UIP, and was more consistent with survival previously re

20 expressed at significantly higher levels in UIP lung biopsies compared with biopsies from patients w

21 Survival was lower in UIP than in fibrotic NSIP (p = 0.001) but not in patient

22 ant STAT3 signaling plays a critical role in UIP/IPF pathogenesis.

23 trends have considerable prognostic value in UIP and NSIP.

24 f the usual interstitial pneumonia type (IPF/UIP) were reviewed.

25 0 deaths during a median follow-up of 42 mo (UIP, 89%; NSIP, 61%, DIP/RBILD, 0%).

26 honeycombing on HRCT and/or confirmation of UIP by biopsy versus patients without either, using pool

27 honeycombing on HRCT and/or confirmation of UIP by biopsy.

28 ristic computed tomographic (CT) features of UIP are predominantly basal and peripheral reticular pat

29 The fibroblast foci of UIP are the leading edge of a complex reticulum that is

30 patients with UIP or NSIP, the mortality of UIP remained higher, p < 0.01, but the 5-yr survival in

31 h IIP, patients with a histologic pattern of UIP in any lobe should be classified as having UIP.

32 psy (n = 22) demonstrated a preponderance of UIP and diffuse alveolar damage.

33 f pentachrome-stained histologic sections of UIP was performed.

34 Staining of UIP lung biopsy specimens demonstrated that phosphorylat

35 uent in DIP/RBILD than in NSIP (p < 0.01) or UIP (p < 0.0005).

36 c index) at 6 and 12 months in 104 patients (UIP, n = 63; fibrotic NSIP, n = 41).

37 athologists as usual interstitial pneumonia (UIP) (47%), NSIP (36%), or desquamative interstitial pne

38 nction between usual interstitial pneumonia (UIP) and nonspecific interstitial pneumonia (NSIP), the

39 patients with usual interstitial pneumonia (UIP) confirmed by surgical lung biopsy.

40 OOP) in 1, and usual interstitial pneumonia (UIP) in 1.

41 Patients with usual interstitial pneumonia (UIP) in all lobes were categorized as concordant for UIP

42 of underlying usual interstitial pneumonia (UIP) or nonspecific interstitial pneumonia, a review of

43 d to compare a usual interstitial pneumonia (UIP) pattern at CT with survival.

44 roup including usual interstitial pneumonia (UIP), desquamative interstitial pneumonia (DIP), nonspec

45 onias comprise usual interstitial pneumonia (UIP), nonspecific interstitial pneumonia (NSIP), desquam

46 patients with usual interstitial pneumonia (UIP), nonspecific interstitial pneumonia, and respirator

47 al features of usual interstitial pneumonia (UIP), on high-resolution computed tomography (HRCT).

48 Usual interstitial pneumonia (UIP), the pathologic correlate of idiopathic pulmonary f

49 with suspected usual interstitial pneumonia (UIP).

50 broblasts from usual interstitial pneumonia (UIP)/idiopathic pulmonary fibrosis (IPF) lungs character

51 ction point (Pflex), upper inflection point (UIP), compliance below Pflex (Cstart), compliance betwee

52 gnosed in clinical practice who had possible UIP with traction bronchiectasis on HRCT and had not und

53 d a large subgroup of patients with possible UIP.

54 psy in select cases when CT shows a probable UIP pattern.

55 highest in DIP/RBILD and higher in NSIP than UIP, p < 0.0005.

56 Median survival of the UIP group was 2.8 yr which is significantly worse (p < 0

57 ps (p < 0.001), although survival in the two UIP groups was comparable (p = 0.16).

58 Patients with UIP have worse survival than patients with other types o

59 When analysis was confined to patients with UIP or NSIP, the mortality of UIP remained higher, p < 0

60 fibroblast lines obtained from patients with UIP relative to patients with other IIP and patients wit

61 s concordant for UIP (n = 51) and those with UIP in at least one lobe were categorized as discordant