ライフサイエンスコーパス: V. parahaemolyticus

1 V. parahaemolyticus displays additional phenotypic versa

2 V. parahaemolyticus lonS complemented E. coli lon mutant

3 V. parahaemolyticus serotype O6:K18 was isolated from th

4 This MLST scheme was applied to 100 V. parahaemolyticus strains isolated from geographically

5 We sequenced 92 V. parahaemolyticus genomes and used the genome of strai

6 A V. parahaemolyticus gene that performed the function of

7 Because many effectors are injected during a V. parahaemolyticus infection, it is not surprising that

8 which genes were suitable for establishing a V. parahaemolyticus cgMLST scheme.

9 age-treated mice displayed protection from a V. parahaemolyticus infection and survived lethal oral a

10 odiesterase via restoration of motility in a V. parahaemolyticus strain previously shown to accumulat

11 y effects of SlAEW and AEW solutions against V. parahaemolyticus may be attributed to the changes in

12 However, not all V. parahaemolyticus isolates swarm proficiently.

13 er resolution and discriminatory power among V. parahaemolyticus strains using WGS data.

14 ibrio species, V. mimicus, V. fluvialis, and V. parahaemolyticus, display lower MBCs of bile, DC, and

15 orum sensing represses TTS in V. harveyi and V. parahaemolyticus.

16 More than 12% of annotated V. parahaemolyticus genes are differentially expressed i

17 showing sustained intestinal colonization by V. parahaemolyticus.

18 cytotoxicity when HeLa cells are infected by V. parahaemolyticus, while complementation of the Deltav

19 mportant insights into the mechanism used by V. parahaemolyticus to cause disease.

20 y gene regions in four species (V. cholerae, V. parahaemolyticus, V. vulnificus, and V. mimicus).

21 species from the genus Vibrio: V. cholerae, V. parahaemolyticus, V. vulnificus, and V. mimicus.

22 attention, as the emergence of a new clone, V. parahaemolyticus O3:K6, has resulted in the first doc

23 sufficient for induction of autophagy during V. parahaemolyticus-mediated cell death and this effect

24 netic analysis of clinical and environmental V. parahaemolyticus originating largely from the Pacific

25 ltilocus sequence typing (MLST) database for V. parahaemolyticus was created in 2008, and a large num

26 Separate clonal complexes were observed for V. parahaemolyticus isolates originating from the Pacifi

27 ral locus in Vibrio species, is required for V. parahaemolyticus fitness in vivo and for induction of

28 multilocus sequence typing (MLST) scheme for V. parahaemolyticus based on the internal fragment seque

29 d genetic markers thought to be specific for V. parahaemolyticus O3:K6 and its clonal derivatives.

30 The assay identified an additional four V. parahaemolyticus isolates among the other 119 isolate

31 cpsQ encodes one of four V. parahaemolyticus homologs in the CsgD/VpsT family, me

32 Genetic diversity in V. parahaemolyticus appears to be driven primarily by fr

33 oxRS to determine the role of these genes in V. parahaemolyticus RIMD2210633, an O3:K6 isolate, and s

34 they may be relative newcomers to growth in V. parahaemolyticus.

35 ative regulators modulates CPS production in V. parahaemolyticus.

36 hat quorum sensing can stimulate swarming in V. parahaemolyticus; it does so via an alternative pathw

37 These data suggest that in V. parahaemolyticus, RpoN plays an important role in car

38 We show that quorum sensing regulates TTS in V. parahaemolyticus.

39 -frame deletion mutation in rpoN (VP2670) in V. parahaemolyticus RIMD2210633, a clinical serogroup O3

40 arahaemolyticus and V. vulnificus, including V. parahaemolyticus pandemic strains.

41 omics-based method to distinguish individual V. parahaemolyticus strains on the basis of their protei

42 the clone carrying the luxR-like locus into V. parahaemolyticus dramatically affected colony morphol

43 Although not itself luminescent, V. parahaemolyticus produces autoinducer molecules capab

44 Application of this MLST scheme to more V. parahaemolyticus strains and by different laboratorie

45 ion profiles of a wild-type strain (NY-4) of V. parahaemolyticus with those of an ExsD deletion mutan

46 Comparative transcriptomic analysis of V. parahaemolyticus isolated from rabbit intestines and

47 l, the functional level, and, in the case of V. parahaemolyticus, the amino acid sequence or protein

48 This work initiates the characterization of V. parahaemolyticus biofilm formation in the OP and TR c

49 his cgMLST scheme to the characterization of V. parahaemolyticus strains provided by different labora

50 In the pandemic clone of V. parahaemolyticus, a histone-like DNA-binding protein,

51 e unique biomarker for the pandemic clone of V. parahaemolyticus, it was possible to rationally desig

52 o the main U.S. West Coast clonal complex of V. parahaemolyticus (sequence type 36 [ST36]) causing oy

53 se results highlight the genetic dynamism of V. parahaemolyticus and aid in refining the genetic defi

54 Here, we report a draft genome of V. parahaemolyticus strain 10329 of the O4:K12 serotype.

55 Whole-genome comparisons of 295 genomes of V. parahaemolyticus, including several traced to northea

56 lagella that inhibits the phage infection of V. parahaemolyticus.

57 ore-detailed pathogenicity investigations of V. parahaemolyticus.

58 ole of quorum signaling in the lifestyles of V. parahaemolyticus, the functional homolog of the gene

59 A portion of the tonB1 locus of V. parahaemolyticus was sequenced and found to encode pr

60 We describe a recognized outbreak of V. parahaemolyticus infection associated with the consum

61 ted to one of the largest known outbreaks of V. parahaemolyticus in the United States.

62 Between 1973 and 1998, 40 outbreaks of V. parahaemolyticus infections were reported to the CDC,

63 ector proteins contribute to pathogenesis of V. parahaemolyticus infection.

64 lular machinery required for phagocytosis of V. parahaemolyticus during infection.

65 tive sigma factors in the stress response of V. parahaemolyticus RIMD2210633, an O3:K6 pandemic isola

66 s C (the theorized threshold for the risk of V. parahaemolyticus illness from the consumption of raw

67 n environmental study to identify sources of V. parahaemolyticus and contributors to the outbreak.

68 d in the first documented pandemic spread of V. parahaemolyticus.

69 Here we show that an AHPND-causing strain of V. parahaemolyticus contains a 70-kbp plasmid (pVA1) wit

70 nce different from those of other strains of V. parahaemolyticus.

71 recise identification of pandemic strains of V. parahaemolyticus.

72 ng the evolution and population structure of V. parahaemolyticus.

73 Vp1659 is specifically secreted by T3SS1 of V. parahaemolyticus, and Vp1659 is not required for the

74 potentially explaining the broad tropism of V. parahaemolyticus, and highlight the utility of genome

75 en for genes that contribute to viability of V. parahaemolyticus in vitro and in the mammalian intest

76 deletion of vopW abrogates the virulence of V. parahaemolyticus in several animal models of diarrhea

77 phage dramatically reduces the virulence of V. parahaemolyticus only when polar flagella were absent

78 four isolates, and all clustered with other V. parahaemolyticus sequences.

79 the pathogenic vibrios tested, particularly V. parahaemolyticus and V. alginolyticus, are similar at

80 r whether these assays detect all pathogenic V. parahaemolyticus strains since a clear correlation be

81 To prevent V. parahaemolyticus infections, persons should avoid con

82 Here, we used RNA-Seq to profile V. parahaemolyticus gene expression in infected infant r

83 We confirmed that deletion of rpoN rendered V. parahaemolyticus nonmotile, and it caused reduced bio

84 nfectivity for multiple-antibiotic-resistant V. parahaemolyticus and V. vulnificus, including V. para

85 odel against a multiple-antibiotic-resistant V. parahaemolyticus pandemic strain infection.

86 cially for the multiple-antibiotic-resistant V. parahaemolyticus pandemic strain.

87 ection using a multiple-antibiotic-resistant V. parahaemolyticus pandemic strain.

88 testinal tract by the streptomycin-resistant V. parahaemolyticus.

89 Between 1988 and 1997, 345 sporadic V. parahaemolyticus infections were reported: 59% were g

90 ikovii (9 strains), V. mimicus (10 strains), V. parahaemolyticus (30 strains), and V. vulnificus (10

91 t appears to infect at much lower doses than V. parahaemolyticus strains with these same determinants

92 We conclude that V. parahaemolyticus, V. vulnificus, V. cholerae and subp

93 Thus, we demonstrate that V. parahaemolyticus can invoke a programme of gene contr

94 ST43, 50, 65, 135 and 417) demonstrates that V. parahaemolyticus gastroenteritis in the Pacific North

95 It is evident that V. parahaemolyticus population structure in the Pacific

96 he data reported in this study indicate that V. parahaemolyticus is genetically diverse with a semicl

97 Our analyses also suggest that V. parahaemolyticus has access to glucose or other prefe

98 The V. parahaemolyticus polar flaC flagellin gene was poorly

99 The V. parahaemolyticus transcriptional response to in vivo

100 so far that these phages can lysogenize the V. parahaemolyticus strain 16 host.

101 We determined the crystal structure of the V. parahaemolyticus PirA and PirB (PirA(vp) and PirB(vp)

102 ion flow through the central elements of the V. parahaemolyticus quorum pathway is proven for the fir

103 s, correctly identified more than 90% of the V. parahaemolyticus strains.

104 cted between 1997 and 2005 revealed that the V. parahaemolyticus chromosome 2 type III secretion syst

105 compared to the functions attributed to the V. parahaemolyticus TDH and TRH proteins.

106 n V. cholerae and P. aeruginosa, whereas the V. parahaemolyticus homolog of one of these regulators,

107 We identified genes that contribute to V. parahaemolyticus colonization of the intestine indepe

108 source of oysters that caused illness due to V. parahaemolyticus.

109 cteria and enhances the phage infectivity to V. parahaemolyticus, indicating that polar flagella play

110 undance was a significant correlate of total V. parahaemolyticus; however, the prevalence of genes co

111 n assay between the DeltatoxRS and wild-type V. parahaemolyticus strains marked with the beta-galacto

112 nowledge of additional factors that underlie V. parahaemolyticus pathogenicity is limited.

113 The 3 commonly reported Vibrio species were V. parahaemolyticus, V. vulnificus, and V. alginolyticus

114 The regulatory mechanism by which V. parahaemolyticus ToxR activates expression of T3SS2 r