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1 WG consumption for 4-8 wk determined a 4-fold increase i
2 WG definitions focus on the principal components of the
3 WG wheat consumption significantly increased excreted FA
4 WG-4 kinks and stiffens the peptide backbone, which may
5 WGs appear to be effective at normalizing blood glucose
8 ly immature this vasculature was, even at 11 WG: no basement membrane, absence of pericytes, and poor
17 protein extracts were immunoblotted with 27 WG patients' sera, 10 Churg-Strauss syndrome (CSS) patie
22 definition for a WG, with a definition for a WG food still in its early stages; a standard definition
23 ists on the main parts of a definition for a WG, with a definition for a WG food still in its early s
24 allele for CTLA-4 expression may represent a WG-related susceptibility mutation that accounts, in par
25 316 overweight and obese participants with a WG intake of <30 g/d were recruited and randomly assigne
26 Fourteen patients were treated for active WG using a standardized regimen of CYC and glucocorticoi
31 h HIV viremia and in individuals with active WG, indicating that expression of this receptor is modul
32 discriminating endogenous metabolites after WG versus refined grain (RG) wheat bread consumption.
33 and Bacteroidetes abundances, whereas after WG consumption, it correlated with increased Bacteroidet
34 leus (0.34 +/- 0.14), RG (0.20 +/- 0.04) and WG (0.15 +/- 0.08); Y was higher in soleus versus both R
35 ith disease activity (P = 1.3 x 10(-4)), and WG patients with low-level expression of the WG signatur
36 1.0; Lo, 15.3 +/- 1.3; Hi, 10.2 +/- 1.6) and WG (mmHg: rest, 19.0 +/- 1.3; Lo, 12.2 +/- 1.1; Hi, 9.9
37 HNE ANCAs may discriminate between CIMDL and WG, whereas a positive test result for PR3 ANCA may not.
40 w-twitch (soleus) versus fast-twitch (RG and WG) muscle during contraction, and (3) relative flux thr
44 omprehensive biomarker pool to better assess WG wheat consumption, and to monitor the endogenous chan
46 hort in which a positive association between WG and longer alleles of (AT)n in the Ctla4 3'-UTR was d
48 ohort studies reporting associations between WG intake and mortality from all causes, cardiovascular
60 hen validated the new, disease-specific BVAS/WG in 2 simulation exercises and a clinical case series
61 mulation exercises was r = 0.93 for the BVAS/WG and r = 0.88 for the PGA in the first and r = 0.91 fo
63 ank correlation coefficient between the BVAS/WG and the PGA was r = 0.81 (95% confidence interval 0.7
64 Correlations between the scores on the BVAS/WG and the physician's global assessment (PGA) of diseas
65 n exercises and in actual patients, the BVAS/WG correlates well with the PGA, is sensitive to change,
72 ngham Vasculitis Activity Score for WG (BVAS/WG) in 20 patients with persistently active disease or w
74 (GSEA) was performed to search for candidate WG-associated molecular pathways and disease activity bi
76 usion exists over which foods are considered WGs and how much is needed to achieve health benefits.
78 uggests that, in contrast to RG consumption, WG wheat consumption may facilitate antioxidant defense
82 out work, conducted in collaboration with Dr WG McKenna, aimed at gaining a better understanding of '
83 (b)M(187-195) response have a distinct "(D/E)WG" motif formed by a limited number of recombination st
85 e, nutrition policy advises consumers to eat WGs for at least one-half of their total grain intake (2
91 the Birmingham Vasculitis Activity Score for WG (BVAS/WG) in 20 patients with persistently active dis
92 y) which was added to standard therapies for WG (glucocorticoids, methotrexate, cyclophosphamide, aza
93 et [-6.8 nmol/g (13.0 nmol/g) dry weight for WG compared with 1.8 nmol/g (12.3 nmol/g) dry weight for
95 subjects and those who consumed 60 or 120 g WG, but not between those who consumed 60 and 120 g WG.
98 ol (no dietary change), intervention 1 (60 g WG/d for 16 wk), or intervention 2 (60 g WG/d for 8 wk f
103 nitive systems, such as Watson for Genomics (WG), integrate massive amounts of new omic data with the
104 r content of the TCR containing the germline WG motif in the CDR3, and a remarkable sharing of one do
105 l human eyes from 5.5 to 12 weeks gestation (WG) were prepared for immunohistochemical analysis or fo
106 al human eyes from 7 to 22 weeks' gestation (WG), using antibodies against PAL-E, PV-1 (fenestrations
109 This study aimed to assess the whole grain (WG) content of foods consumed in the UK which include in
111 indings on associations between whole grain (WG) intake and mortality are inconsistent and have not b
112 Mounting evidence suggests that whole grain (WG) intake plays an important role in chronic disease pr
130 PSV, subgroups (47 Wegener's granulomatosis [WG], 12 microscopic polyangiitis, 16 Churg-Strauss syndr
131 ncreased in the whole grain-rich diet group (WG) but not in the refined grain-based diet group (RG) (
133 Institute (NHLBI) convened a Working Group (WG) on August 5 to 6, 2010 in Bethesda, Maryland to disc
134 ect organizers established 4 working groups (WGs) to address the following themes: 1) nutrient specif
138 2 can interact with hAgo via three of the GW/WG repeats in its Argonaute-binding domain: motif-1, mot
140 ), we generate expression datasets (Illumina WG 6.2 arrays) in the normal mouse retina and 2 days aft
141 ic transcriptome was profiled using Illumina WG-6v2.0 chip in control and AngII infused (490 ng/kg/mi
146 r genetic studies of immune dysregulation in WG, the pathogenesis of which may be facilitated by mult
152 ssion values of the 86 up-regulated genes in WG PBMCs were associated with disease activity (P = 1.3
154 cells infiltrating granulomatous lesions in WG, we investigated the proliferative response and cytok
155 ed that the fold change in PR3 RNA levels in WG PBMCs corresponded to changes in the BVAS-WG score ov
156 alse discovery rate [FDR] 0.002), but not in WG PMNs (P = 0.03, FDR 0.28), and a preliminary longitud
158 nscription was significantly up-regulated in WG PBMCs (P = 1.3 x 10(-5), false discovery rate [FDR] 0
160 ity.We assessed the effects of diets rich in WGs compared with refined grains (RGs) on immune and inf
161 nt differences between patients with limited WG and those with severe WG with regard to sex, age, the
165 oxidative (soleus) versus glycolytic muscle (WG) during rest and in slow-twitch (soleus) versus fast-
171 National Cancer Institute Working Group (NCI-WG) guidelines, the complete response (CR) rate as asses
172 ancer Institute-sponsored Working Group (NCI-WG) response criteria for chronic lymphocytic leukemia (
175 nalysis demonstrated inverse associations of WG intake with total and cause-specific mortality, and f
176 udies, was used to investigate biomarkers of WG wheat intake and further explore the diet-disease ass
177 developed to follow a hypothetical cohort of WG patients over their lifetimes starting from the time
178 ds consumed confirms the low contribution of WG foods to the overall pattern of foods consumed in the
180 ed all patients who had a first diagnosis of WG during 1990-2005, using Oxford Information System and
187 aining <51% WG accounted for the majority of WG food codes identified, recognising the importance of
188 lasma alkylresorcinols (compliance marker of WG intake) were measured at baseline and at 6 and 12 wk.
189 d plasma total alkyresorcinols (a measure of WG intake) (P < 0.0001), stool weight (P < 0.0001), stoo
197 tion, excretion, and the physiologic role of WG wheat polyphenols in subjects with suboptimal dietary
200 ive, standardized trial for the treatment of WG was performed using CYC and glucocorticoids for remis
202 ept and cyclophosphamide in the treatment of WG, indicate that the combination of TNF inhibition and
204 concentrations.The short-term consumption of WGs in a weight-maintenance diet increases stool weight
207 Herein, wheatgrass-derived oligosaccharides (WG-PS3) were isolated and found to induce CD69 and Th1 c
208 ommon amino acids) was exposed to HOCl, only WG produced a high yield of the chloroindolenine derivat
209 secutive patients with refractory ophthalmic WG treated with rituximab were retrospectively reviewed.
214 ctively in the discs also promoted premature WG, CUT and SENS expression in the wing discs of sucrose
215 istory items, and information about previous WG treatments and risk factors for malignancy were recor
217 the formation of a novel oxidation product, WG-4, through modification of adjacent tryptophan and gl
218 porting relative risks for >/=3 quantitative WG categories, and they were <50 g/d among most study po
219 h convened in Washington, DC, and recognized WG definitions as a key nutrition and public health-rela
220 asma AR concentrations reflect self-reported WG food intake in a 16-wk WG intervention study and to e
223 d to map 5fC/5caC at the whole-genome scale (WG-MAB-seq), within specific genomic regions enriched fo
224 st R(2) with the PGA was obtained by scoring WG activity based on the following items: the 25 predefi
226 tients with limited WG and those with severe WG with regard to sex, age, the likelihood of recurrent
236 ets for 6 wk.Compared with the RG group, the WG group had increased plasma total alkyresorcinols (a m
237 mall compared with other patient groups, the WG strongly urged concerted efforts to enroll every tran
238 centrations of menaquinones decreased in the WG diet compared with the RG diet [-6.8 nmol/g (13.0 nmo
240 umor necrosis factor-alpha (P = 0.04) in the WG group than in the RG group, which were positively ass
245 ined, the favorable energetic effects in the WG translated into a 92-kcal/d (95% CI: 28, 156-kcal/d)
250 esorcinols increased with consumption of the WG diet and did not change with consumption of the RG di
251 WG patients with low-level expression of the WG signature genes showed expression profiles that were
254 plasma AR concentrations increased with the WG intervention and could be used to distinguish between
255 ons focus on the principal components of the WGs and their proportions, whereas WG-food definitions d
256 t Wingless signaling reduces ACF1 binding to WG targets, and ISWI and ACF1 regulate repression by ant
260 important disease manifestations specific to WG, and to streamline the instrument for use in clinical
262 al care have, for most patients, transformed WG from being a disease with a high potential for short-
263 udy was to understand the biology underlying WG and to discover markers of disease activity that woul
264 ts of the WGs and their proportions, whereas WG-food definitions describe the quantity of WGs present
266 , drug allergy (with PSV 3.6 [1.8-7.0], with WG 4.0 [1.8-8.7], and with cANCA 4.7 [1.9-11.7]), and al
267 he index year (with PSV 3.4 [0.9-12.5], with WG 4.8 [1.2-19.8], and with classic ANCA [cANCA] 3.9 [1.
268 cohort of 604 consecutive patients (64 with WG, 14 with microscopic polyangiitis [MPA], and 526 othe
269 ted with PSV (OR 2.3 [95% CI 1.2-4.6]), with WG (2.7 [1.2-5.8]), with MPA (6.3 [1.9-21.6]), and with
270 rking lifetime (with PSV 2.7 [1.1-6.6], with WG 3.4 [1.3-8.9], and with cANCA 3.3 [1.0-10.8]), drug a
273 ead exposure were positively associated with WG as compared with either control group, although the n
276 lasma AR concentrations were correlated with WG intake and could be used to distinguish between low-
280 d by telephone interview to 53 patients with WG and 2 control groups: one with osteoarthritis and the
285 Sera from 61 PR3 ANCA-positive patients with WG or MPA were assayed by capture enzyme-linked immunoso
288 and CD4+ T cells isolated from patients with WG was elevated, when compared with healthy donors.
291 dnisone as initial therapy for patients with WG-related glomerulonephritis and a normal or near-norma
297 lect self-reported WG food intake in a 16-wk WG intervention study and to establish which phenotypic
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