ライフサイエンスコーパス: WT

1 WT and B2-deficient mice were infected with H1N1 PR8 by

2 WT mice (5-20 mo) were investigated in a cross-sectional

3 WT mice that received LY2828360 coadministered with morp

4 WT, p40(-/-), and p35(-/-) mice fed an HFD become obese

5 WT-, SA-, and SE-Brg1 exhibited distinct differences in

6 s 8-37 showed potent inhibition of the HIV-1 WT NL4-3 strain and of the mutant K103N, Y181C, Y188L, a

7 In contrast, a second segment, 15-25 WT, forms non-toxic labile beta-sheets.

8 om both Abeta and hIAPP, termed Abeta(24-34) WT and hIAPP(19-29) S20G, with 64% sequence similarity.

9 C57BL/6 WT, tlr4(-/-) and IL10(-/-) mice were exposed to LPS, an

10 onal skin of patients with FLG wild-type AD (WT/WT), FLG-mutated AD (FLG/WT), IV (FLG/FLG), or FLG WT

11 s in the NaV1.5 proteins purified from adult WT and failing CaMKIIdeltac-overexpressing (CaMKIIdeltac

12 galin expression remained unaltered in adult WT and KO mouse brain, SC, and kidneys.

13 1,25(OH)2D3 did not affect WT cell proliferation, but did stimulate VDR KO cell pro

14 (Scn8a(D/+)), homozygous (Scn8a(D/D))), and WT (Scn8a(+/+)) littermates were compared at 3 weeks of

15 TLR2-, TLR4-, MyD88-deficient and WT BALB/c mice were intratracheally challenged with PM2.

16 oteins possessing one or more WW domains and WT or PPXY mutant peptides of eVP40.

17 u inclusions consisted of both T40PL-GFP and WT endogenous mouse tau.

18 ure of A2V Abeta1-6 (Abeta6) hexapeptide and WT Abeta1-42 (Alphabeta42) is also found neuroprotective

19 ference in IgE production between VDR KO and WT cultures.

20 man amyloid precursor protein (APP mice) and WT mice.

21 ity (LMA) were recorded in Taar1 KO, OE, and WT mice.

22 Expression of MR was similar in RacET and WT mice.

23 tected pathologic alterations between TG and WT mice, only (18)F-AV45 could detect an effect of BACE

24 iptome changes in hyperoxia-exposed animals (WT versus knock-out) identified 171 genes unique to Cyp1

25 d Ig21 by displacing Ig20 from autoinhibited WT filamin, but surprisingly, the capacity of these liga

26 ce in the number of alveolar lesions between WT and Tlr2/4(-/-) mice.

27 e that were differentially regulated between WT, Cyp1a1-/- and Cyp1a2-/- mice.

28 current amplitude and action spectra between WT and the Opn4-expressing Drosophila further indicated

29 Both WT and KO mice discriminated between reward and no-rewar

30 d an increase in hydrodynamic volume in both WT and dimeric CaMKII without altering subunit stoichiom

31 egalin expression was about the same in both WT and KO mouse visceral yolk sac, brain, and spinal col

32 Co-expression of both WT and mutant CSPalpha cause a block in the fusion of au

33 gher molecular mass and activity, while BRAF(WT) is confined to smaller, slightly less active complex

34 nd genomic instability, which was rescued by WT GINS1.

35 t the single channel level compared with CaM-WT.

36 minant-negative manner to reduce CaMKIIalpha-WT autophosphorylation.

37 tly augmented cardiac apoptosis in WT vs. CD-WT mice, which was prevented by co-treatment with the re

38 VDR wildtype mouse corneal epithelial cells (WT), 1,25(OH)2D3 increased CYP24A1 protein expression an

39 was significantly reduced in HDM-challenged WT mice.

40 were significantly increased in cholestatic WT mice and significantly blunted in TRPC5 KO mice.

41 significantly higher than the corresponding WT region and, interestingly, the expression of the only

42 il and monocyte/macrophage lineages than did WT progenitors in myeloid colony-forming unit assays, su

43 On a high-salt diet, WT mice with Tmem27(Y/-) kidneys had the highest systoli

44 a dominant negative by partially disrupting WT CAV1 trafficking.

45 0% of the genes that are repositioned during WT development.

46 tion between the subcellular pools of the E2(WT) protein occurred upon ChlR1 silencing.

47 er demonstrate the importance of eliminating WT virus contamination in an animal model of gammaherpes

48 ompared with mice expressing virally encoded WT melanopsin; however, the phase angle of entrainment a

49 HNO enhanced WT kinase activity, an effect significantly attenuated i

50 n the inhibition by morphine for DOP-/- c.f. WT neurons and a DPDPE-induced decrease of IPSC frequenc

51 Liver histology showed that only WT fed FF (WT-FF) developed NASH and fibrosis.

52 LG-mutated AD (FLG/WT), IV (FLG/FLG), or FLG WT control skin, we assessed the potential autocrine rol

53 ved eicosanoids in FLG-associated versus FLG-WT AD pathogenesis.

54 Both AD (FLG/WT) and IV (FLG/FLG) HEEs showed impaired late epidermal

55 Only AD (FLG/WT) HEEs exhibited significantly increased levels of inf

56 LG wild-type AD (WT/WT), FLG-mutated AD (FLG/WT), IV (FLG/FLG), or FLG WT control skin, we assessed t

57 and a lower IFN response compared with FLT3-WT AML samples.

58 swelling and membrane depolarization in FRD-WT mice but not in FRD-S2814A mice, in which the CaMKII

59 c and metastatic, whereas those derived from WT mice treated with pIL6 ((IL6) WT LSCs) had significan

60 ect was rescued by bone marrow exosomes from WT, but not miR-155(-/-), cells, suggesting that uptake

61 ibrogenic hepatic stellate cells (HSCs) from WT and TLR4-KO mice were assessed in vitro.

62 s accurately discriminated UCP3 Tg mice from WT when modeled within a specific exercise condition (i.

63 n Ca(2+) transients in cardiac myocytes from WT but not CD38(-/-) mice.

64 Increasing charge segregation from WT RAM sharply decreases transcriptional activation for

65 acellular matrix was similarly reduced in GF WT, Tlr2(-/-) , and heterozygous Vwf(+/-) mice that are

66 mouse models in combination with CX3CR1(GFP/WT);CCR2(RFP/WT) double knock-in mice.

67 2 in the hematopoietic compartment (TLR2KO-->WT) was comparable to TLR2KO mice.

68 munopathology compared with wild-type (WT)-->WT chimeric mice.

69 rkers were increased in the lungs of healthy WT mice treated with recombinant murine CIRP, but not in

70 H-mutated (IDH-MUT) tumors compared with IDH-WT tumors.

71 y complex than that formed from IkappaBalpha(WT) because DNA dissociated more slowly.

72 erived from WT mice treated with pIL6 ((IL6) WT LSCs) had significantly less proliferation and no tum

73 In WT mice, PM2.5 + OVA exacerbated OVA-related lung eosino

74 In WT mice, the addition of elacridar (at systemic plasma c

75 In WT-infected mice, infiltrates in gastric tissues were pr

76 only a minor fraction (30-40%) of the 26S in WT mouse embryonic fibroblast cells.

77 97 and either Thr-500, Ser-510 or Thr-513 in WT-GC-A increased the Km 23- to 70-fold but the same mut

78 the response of NPQ to light acclimation in WT and mutant plants were observed between two successiv

79 TORC1 signaling in alphaRaptorKO mice and in WT animals exposed to chronic rapamycin administration d

80 significantly augmented cardiac apoptosis in WT vs. CD-WT mice, which was prevented by co-treatment w

81 he expression of cytokines and chemokines in WT and TLR4-KO HSCs.

82 in expression of cytokines and chemokines in WT and TLR4-KO mice.

83 inhibition of [(3)H]DA uptake by cocaine in WT hDAT.

84 HFD, blood flow recovery was compromised in WT mice, whereas it was fully recovered in p40(-/-) and

85 knockout dams, and antigen concentrations in WT amniotic fluid (AF) were higher than in IgG-free AF o

86 sults indicate that asymmetric conduction in WT M2 is due to W41 inhibition of C-terminal acid activa

87 bile acid and lipid content was elevated in WT mice, with a reduction observed in TRPC5 KO mice.

88 collective frequency of unbinding events in WT-RBCs is not significantly different from that of SS-R

89 ation and estrogen target gene expression in WT and mutant ER-containing cells and were more effectiv

90 cking Abs attenuated BDL-induced fibrosis in WT mice.

91 cells at more than 10-fold the frequency in WT cells.

92 matin features of inactive X-linked genes in WT and Eed (-/-) TSCs suggests that PRC2 acts as a brake

93 e that this clearance is nearly identical in WT and Ccr2(-/-) mice, and that neutrophils replace CCR2

94 saturate LTD produced the same impairment in WT as observed in DKO mice.

95 ene induction was significantly increased in WT mice, including sterol regulatory element-binding pro

96 tein markers were significantly increased in WT-FF.

97 Acute CCl4 -mediated liver injury in WT mice induced endogenous CcnE1 expression and prolifer

98 ly moderate effects on bile acid kinetics in WT mice, but completely inhibited active transport of co

99 e size of tumors was significantly larger in WT mice, whereas there was no difference in the number o

100 denine), markedly increased PNPLA3 levels in WT mice, coincident with the appearance of ubiquitylated

101 y (1.8-fold) up-regulated Pxr mRNA levels in WT mice.

102 ay 1 postinfection compared to the levels in WT mice.

103 oa than WT capacitated controls and lower in WT spermatozoa treated with the PRDX6 inhibitor.

104 olonged in DREAM KO control mice, but not in WT or DREAM bone marrow chimeric mice.

105 genes were down-regulated in cbl1 but not in WT roots.

106 p-regulation of a large set of genes only in WT and not cbl1 shoots, while a different set of genes w

107 and diastolic function were present only in WT mice, and not in PAD4(-/-) mice.

108 production, and transgenic overexpression in WT mice exacerbates these phenotypes.

109 letely resolved in Darc(E2) but persisted in WT mice.

110 esterol, triglycerides and phospholipids, in WT, but not TRPC5 KO mice.

111 of OSBPL3 facilitates SREBP-1 processing in WT mice, while silencing hepatic Osbpl3 reverses the lip

112 egrin activation, reduced IFN-I responses in WT but not CD11b-deficient mice, and protected lupus-pro

113 ion, MNCV, and CMAP almost to levels seen in WT animals.

114 histidines to the neutral state, as seen in WT M2, but left half of all histidines cationic, unambig

115 ansdifferentiation and fibrotic signaling in WT BM-FPCs in vitro.

116 d that these genes are direct VDR targets in WT keratinocytes.

117 l line )) were higher in Prdx6 (-/-) than in WT spermatozoa (p </= 0.05).

118 heterozygous KI mice were similar to that in WT mice.

119 were present in numbers similar to those in WT animals and functionally intact, and transfer of WT p

120 day x 12 days) blocked morphine tolerance in WT but not in CB2KO mice.

121 ation, as reducing protofilament turnover in WT is not sufficient to induce bundling.

122 pared to elevated K48-poly-ubiquitination in WT cells, indicating increased stability of NUMBL in TAK

123 miR-155 was 10-fold upregulated in WT-derived ILC2s in response to IL-33.

124 yte size, and reduced insulin sensitivity in WTs.

125 lpha DNA-binding domain mutation knocked in (WT/KI) to produce WT, ERalpha KO, or ERalpha KIKO female

126 lungs compared with M. tuberculosis-infected WT mice.

127 Following infection, WT mice mounted more robust humoral and cellular immune

128 early but not at later stages of infection, WT mice had higher circulatory proinflammatory cytokines

129 ants by as much as 80% but failed to inhibit WT-GC-B.

130 HDM-pulsed LRP-1-deficient CD11b(+) DCs into WT mice generated a similar phenotype of enhanced eosino

131 his question, heterozygous ERalpha knockout (WT/KO) dams were fed a control breeder chow diet (25% fa

132 ound/internalized LDL, as compared with LDLR-WT.

133 and MCF-7 breast carcinoma, B16F10 melanoma, WT-GBM glioma and MKN45-P gastric carcinoma.

134 o activation with CaM in the dimeric mutant, WT-holoenzyme, and a monomeric CaMKII oligomerization-do

135 cts with these sequences in VDR(-/-) but not WT keratinocytes.

136 gation, IVC thrombosis was evident in 60% of WT mice and 25% of pcsk9 (-/-) mice (p < 0.05).

137 We also showed that the ability of WT HBx-expressing cells to form tumors in nude mice was

138 CD3(-)NK1.1(+) NK cells into the airways of WT hosts suppressed the inflammatory response.

139 ormation of NIH 3T3 mouse fibroblasts and of WT KRAS to rescue the growth defect of mouse embryonic f

140 A comparison of WT and Gsk3a;Gsk3b knock-out (Gsk3 DKO) ESCs revealed pr

141 An analysis of primary root growth of WT, med12, aux1-7 and med12 aux1 single and double mutan

142 1-108-alphaS fibrils resist incorporation of WT-alphaS monomers.

143 ient fibroblasts was comparable to levels of WT IFNAR1 in control fibroblasts.

144 uction neutralization test) using a panel of WT JE strains at baseline, then after the booster at 28

145 Preincubation of WT-TTR with small molecules that occupy the T4 binding s

146 ion, and CRISPR-Cas9-mediated replacement of WT KRAS with a mutant allele sensitized heterozygous mut

147 gration to CNS compared with the response of WT Th17 cells and thereby ameliorated EAE.

148 nt cell type, we measured the stabilities of WT ROMK and the ROMK Bartter mutants in HEK293 cells.

149 We previously reported a structure of WT human P450 21A2 with bound progesterone and now prese

150 5) variants had stability similar to that of WT FrdA, contained noncovalent FAD, and displayed a redu

151 als and functionally intact, and transfer of WT platelets did not restore arthritis susceptibility.

152 Furthermore, transplantation of WT bone marrow into miR-155KO mice mitigated this phenot

153 in proteins, preferentially adopting the OF (WT) and IF (5L6-8) states either in the presence or abse

154 Liver histology showed that only WT fed FF (WT-FF) developed NASH and fibrosis.

155 ukin-6 (IL-6) relative to BALB/cJ and PDE11A WT mice, respectively.

156 allergen transfer was detectable in pregnant WT mice but not in pregnant B-cell knockout dams, and an

157 duced by DeltaVlsE and yet failed to prevent WT-induced spirochetemia.

158 omain mutation knocked in (WT/KI) to produce WT, ERalpha KO, or ERalpha KIKO females lacking ERE-depe

159 in kinase, whereas the overexpression of Ras-WT enhanced it.

160 GSNOR KO animals receiving WT bone marrow had significantly reduced survival follow

161 in combination with CX3CR1(GFP/WT);CCR2(RFP/WT) double knock-in mice.

162 Finally, we demonstrate that Rheb-WT can bind AMPK to facilitate AMPK activation, whereas

163 depletion of satellite cells compared to SC-WT (P < 0.05).

164 by severity and length of vaginal shedding, WT C57BL/6 and HLA-DR4 mice were significantly protected

165 sitive to c-MYC inhibition than that of Spop-WT cells, suggesting that c-MYC upregulation functionall

166 tly, swelling of MyD88(-/-) joints surpassed WT joint swelling, and resolution of joint inflammation

167 ts on PSI isolated from Arabidopsis thaliana WT in dark-adapted and high-light-stressed (NPQ) states,

168 w-derived macrophages produced more A20 than WT cells following P. gingivalis challenge.

169 p14 had higher basal peptidase activity than WT 26S, and this activity was stimulated to a greater ex

170 tiporter 3, and lower lithium clearance than WT mice.

171 neurons were more susceptible to death than WT neurons and formed Htt aggregates under the condition

172 distance and a higher solvent exposure than WT-alphaS fibrils, which is also indicated by the pronou

173 CD18(-/-) leukocytes extravasated later than WT leukocytes.

174 non-ubiquitinated proteins (e.g. Sic1) than WT particles.

175 in Prdx6 (-/-) capacitated spermatozoa than WT capacitated controls and lower in WT spermatozoa trea

176 ed significantly lower (18)F-FDG uptake than WT mice in the thalamus (P = 0.0004) and hippocampus (P

177 BPND in the striatum was lower in zQ175 than WT animals by 40% for (11)C-raclopride, by 52% for (18)F

178 Here, we demonstrate that WT mice treated with CLP for 2 weeks had significantly r

179 emoval was 87% in the CYP2E1 bed, 85% in the WT bed, and 34% in the unplanted bed in 2012.

180 ieving high proton-pumping efficiency in the WT CcO.

181 y more inflammatory cell infiltration in the WT ligated but not in the TLR9(-/-) ligated mice compare

182 t the subcellular distribution of FRQ in the WT, highly elevated FRQ levels were detected in the nucl

183 al tissues compared to its expression in the WT.

184 re smaller in CD38(-/-) myocytes than in the WT.

185 embryos/mouse) compared to the levels of the WT controls (9.1 +/- 0.4 embryos/mouse) (P < 0.05).

186 by restoration of just normal levels of the WT Hsp104.

187 different RNAs, we find that features of the WT SHAPE reactivity allow us to improve thermodynamic st

188 72Q) exhibited less phosphorylation than the WT enzyme and a deacetylation-mimicking mutant (K72R).

189 Addition of purified Usp14 to the WT and Usp14-defficient proteasomes reduced both their b

190 w titers of OVA-specific IgE compared to the WT-OVA/alum model.

191 y cytoplasmic in the HeLa cells; whereas the WT-MIP was stable dispersed throughout the cytoplasm, an

192 like (DNM1L) protein-knockout mice or their WT littermates.

193 D11b(+) pulmonary dendritic cells than their WT controls at the baseline and after sensitization with

194 lso exhibited faster deactivation than their WT counterparts, revealing that these substitutions impa

195 ocytes transmigrated more rapidly than their WT counterparts.

196 ith the A2V and A2T hexapeptides compared to WT Abeta6.

197 uced transendothelial resistance compared to WT cells.

198 ct on health or development, and compared to WT controls, Foxp3+ Tregs lacking HDAC11 showed increase

199 ic steatosis in the LTKO mice as compared to WT controls.

200 Compared to WT leukocytes, CtsB(-/-) leukocytes accumulated in a hig

201 clustered in the mutant channel compared to WT M2.

202 displayed less hepatic fibrosis compared to WT mice in two separate murine models: CCl4 and bile duc

203 generated from Erk5 (fl/fl) mice compared to WT mice.

204 (115.0 +/- 16.1 min, p < 0.001) compared to WT PAEC (34.0 +/- 8.2 min).

205 and diminished FOXO4 expression compared to WT-iPSC-derived neurons.

206 anastomotic leakage (P = 0.003) compared to WT.

207 eening demonstrates comparable efficiency to WT Cas9, which indicates the suitability of our approach

208 x interaction can be restored by exposure to WT plasma or to purified VWF depending on the VWF integr

209 ax7- and myogenin-positive cells relative to WT muscles, suggesting that dyW-/- muscles fail to gener

210 te a dramatic increase in pSTAT3 relative to WT muscles.

211 but not all, TnT mutants for Tm relative to WT TnT.

212 %; both [ATP] and [5-InsP7] were restored to WT levels by overexpression of PPIP5K1, and a kinase-com

213 uggesting intersubunit affinities similar to WT.

214 ributes to aneuploidy tolerance in both TP53-WT and mutant cells by reducing basal caspase-2 levels a

215 m latently HSV-1-infected, glutamine-treated WT mice showed upregulation of several IFN-gamma-inducib

216 staining in DP1(-/-) and laropiprant-treated WT groups were observed.

217 ound in LanCL1 knock-out, TKO and wild type (WT) mouse brains, suggesting that LanCL proteins are not

218 Compared to the wild type (WT), the inactivation of misR identified 157 differentia

219 ltifilament bundles compared with wild type (WT).

220 with 80% of them also modified in wild type (WT).

221 phologies similar to those of the wild-type (WT) A24 Cruzeiro strain in BHK cells, and both high- and

222 Wild-type (WT) and B cell-deficient mice received ovalbumin (OVA) i

223 Male wild-type (WT) and Cyp2e1-null mice were fed standard chow or FF fo

224 C57BL/6 wild-type (WT) and IL-15(-/-) mice were sensitized and challenged w

225 differentially expressed between wild-type (WT) and Nrf2(-/-) mice in both preterm and control sampl

226 Wild-type (WT) and TG mice received vehicle or BACE inhibitor (60 m

227 XO transcription factors in three wild-type (WT) and three HD induced-pluripotent stem cell (iPSC) li

228 ic serum nephritis was induced in wild-type (WT) and ubiquitin-binding deficient ABIN1[D485N] mice, a

229 In wild-type (WT) animals, administration of CL-316,243, a selective b

230 ed in MCMV-infected Ebi3(-/-) and wild-type (WT) B6 mice.

231 response to darkness but exhibits wild-type (WT) behaviour when exposed to abscisic acid (ABA) or CaC

232 ity reduction was elicited in the wild-type (WT) C57BL/6 mice (4.3 +/- 1.4 embryos/mouse) compared to

233 Moreover, when coexpressed with wild-type (WT) CAV1 in Cav1(-/-) MEFs, CAV1-P158 functions as a dom

234 e proton-pumping mechanism of the wild-type (WT) CcO, much attention has been given to the mutation o

235 ctivate M2 gene expression in the wild-type (WT) cell line, but not in the knockdown cell line.

236 of less fit cells, or losers, by wild-type (WT) cells, influencing overall tissue health.

237 odel, we found that compared with wild-type (WT) control and nonhematopoietic DREAM knockout (KO) mic

238 ed enhanced mortality compared to wild-type (WT) controls, while mice lacking the necroptotic effecto

239 lls compared with the age-matched wild-type (WT) controls.

240 ated vascular leakage compared to wild-type (WT) counterparts.

241 secreted higher IgE ex vivo than wild-type (WT) cultures, and the addition of IL-10 eliminated the d

242 Here we demonstrate that wild-type (WT) FAM46C overexpression induces substantial cytotoxici

243 enotypes could be complemented by wild-type (WT) hematopoietic cells or administration of exosomes pr

244 c rats are indistinguishable from wild-type (WT) insulin.

245 ragenic ouf suppressors with near wild-type (WT) JA pathway activity were recovered and one mutant, o

246 that shortly after phagocytosis, wild-type (WT) L. monocytogenes escaped from a noncanonical autopha

247 e were examined and compared with wild-type (WT) littermates following intranasal exposure to HDM all

248 lithium responsivity relative to wild-type (WT) littermates in tail suspension, an antidepressant-pr

249 Pcsk9 deficient (pcsk9 (-/-)) and wild-type (WT) littermates underwent partial inferior vena cava (IV

250 quencing of ATXN2Q127 mice versus wild-type (WT) littermates.

251 crease of 10-300 fold compared to wild-type (WT) merozoites.

252 Wild-type (WT) mice either were or were not (controls) exposed to c

253 ponding to peak LCN2 induction in wild-type (WT) mice injected with LPS, Lcn2(-/-) mice challenged wi

254 nt and FXII-deficient mice and in wild-type (WT) mice pretreated with a PKal inhibitor prior to tPA.

255 gene knockout (Adipoq(-/-) ) and wild-type (WT) mice were crossed to produce pregnant mouse models w

256 -155 deficient (miR-155(-/-)) and wild-type (WT) mice were subjected to acute or chronic allergen-ind

257 ing rest and activity compared to wild-type (WT) mice, and smaller responses to chemoreceptor activat

258 Compared with cisplatin-treated wild-type (WT) mice, cisplatin-treated MIOX-TG mice had even greate

259 In wild-type (WT) mice, LY2828360 (3 mg/kg per day i.p. x 12 days) sup

260 When inoculated into naive wild-type (WT) mice, this persistently circulating CHIKV strain dis

261 ttenuate development of asthma in wild-type (WT) mice, with both naturally occurring regulatory T (nT

262 Compared with the wild-type (WT) rat, Cyp3a1/2 expression was completely absent in th

263 with RhoGAPArg85'Ala relative to wild-type (WT) RhoGAP.

264 sphorothioate bonds modified on a wild-type (WT) specific sink inhibit the Exo III digestion; thus, s

265 Unexpectedly, in wild-type (WT) TSCs these genes are transcribed and are enriched fo

266 nity, and protection of mice from wild-type (WT) WNV infection.

267 Human healthy (wild-type (WT)) and homozygous sickle (SS) red blood cells (RBCs) e

268 is present, which, in contrast to wild-type (WT), leads (A) to the loss of the V27 pocket for the ada

269 To induce type 2 diabetes, wild-type (WT), p40IL-12(-/-) (p40(-/-)), and p35IL-12(-/-) (p35(-/

270 ary immunopathology compared with wild-type (WT)-->WT chimeric mice.

271 Mfc)/190JChdi, CHDI-81003003) and wild-type (WT, C57BL/6J) animals were imaged with the dopamine D2 r

272 ts and Methods Mutation analyses (wild-type [WT] and mutant) for TP53, KRAS, and EGFR were determined

273 synaptic targeting of GluK1 because, unlike WT Neto2 and the phosphodeficient mutant Neto2 S409A, th

274 lammation and injury in previously untreated WT and TLR4-KO mice.

275 C) line carrying the V247fs mutation (V247fs-WT and V247fs-MT), and iPSC line in which the V247fs mut

276 /Hsc70 inhibitors as well as Hsc70 variants (WT & E175S).

277 emotherapy with TP53/KRAS comutations versus WT/WT (hazard ratio, 2.49 [95% CI, 1.10 to 5.64]; P = .0

278 ased and the duration decreased in KO versus WT rats.

279 Here, we utilize comparative S672R versus WT NMR analyses to show that the S672R mutation results

280 This phenomenon was corroborated when WT mice were treated with a CB2-specific antagonist that

281 ay the same number of myofibers as wildtype (WT) muscles, but by E18.5 dyW-/- muscles are significant

282 fat plus cholesterol diet (HFC)-on wildtype (WT) and liver-specific Foxo1/3/4 triple knockout mice (L

283 O exhibited higher SK current than wildtype (WT) and apamin prolonged their APs.

284 24-48 h reperfusion compared with wildtype (WT) counterparts.

285 the striatum of zQ175 mice as compared with WT animals, in agreement with data obtained in clinical

286 ng in the hippocampus of zQ175 compared with WT animals.

287 SPIN showed decreased survival compared with WT bacteria after phagocytosis by neutrophils.

288 c MSCs of TLR4-deficient mice, compared with WT cardiac MSCs.

289 dams was significantly reduced compared with WT dams.

290 D mice had increased steatosis compared with WT HFD mice.

291 Compared with WT mice injected with LPS, Lcn2(-/-) mice injected with

292 cant increase in pSTAT3 levels compared with WT myotubes, indicating that alpha7beta1 can act as a ne

293 finity (10-fold increase in Ki compared with WT RGS2 in a flow cytometry competition binding assay).

294 a reduced GTP hydrolysis rate compared with WT, but this altered activity does not account for bundl

295 te shift toward high spin by comparison with WT OleTJE, indicating the key role of His(85) in this pr

296 d HFD (45% fat) 4 weeks prior to mating with WT/KO males or heterozygous males with an ERalpha DNA-bi

297 NIK transgenic Tregs competed poorly with WT Tregs in vivo and produced pro-inflammatory cytokines

298 '-O-(thiotriphosphate) (ATPgammaS) than with WT particles.

299 HCV pseudotype viruses similar to those with WT E1E2.

300 sured in ABIN1[D485N] mice transplanted with WT mouse bone marrow.

301 ow that the position occupied by W972 within WT Arkadia is critical for the function of RING and that