ライフサイエンスコーパス: Watson-Crick base pair

1 the carrier ligand and secondarily to form a Watson-Crick base pair.

2 nformation like that observed with a matched Watson-Crick base pair.

3 gnificant destabilization of the 5'-flanking Watson-Crick base pair.

4 and therefore can accommodate only a single Watson-Crick base pair.

5 TP), and that the fit is better for a normal Watson-Crick base pair.

6 ed with the enzymatic formation of a natural Watson-Crick base pair.

7 ide that stacks onto the pseudo-knot-closing Watson-Crick base pair.

8 modates the wobble base pair better than the Watson-Crick base pair.

9 steric clashes that would be produced by the Watson-Crick base pair.

10 scent 'base' is nearly as large as an entire Watson-Crick base pair.

11 ith a closed protein conformation and pseudo-Watson-Crick base pair.

12 rather than the major groove as in a normal Watson-Crick base pair.

13 residues A5 and U14 do not form an expected Watson-Crick base-pair.

14 *G mispair is comparable to that of the four Watson-Crick base pairs.

15 fic lesions to bypass and favor distinct non-Watson-Crick base pairs.

16 elative to the stability of a helix with all Watson-Crick base pairs.

17 by 0.4 kcal/mol than bulge loops adjacent to Watson-Crick base pairs.

18 helices that comprise canonical Watson-Crick/Watson-Crick base pairs.

19 es that contain either isosteric GU pairs or Watson-Crick base pairs.

20 vely) more efficiently than nicks containing Watson-Crick base pairs.

21 te for phosphodiester bond formation between Watson-Crick base pairs.

22 processed up to 400-fold faster than stable Watson-Crick base pairs.

23 A hairpin duplex and a similar DNA with only Watson-Crick base pairs.

24 the sequences with other mismatched or with Watson-Crick base pairs.

25 cal reactivity but are able to form standard Watson-Crick base pairs.

26 and entropy per base values associated with Watson-Crick base pairs.

27 ne adenine pK(a) values for a variety of non-Watson-Crick base pairs.

28 extended by human Pol(iota) compared to the Watson-Crick base pairs.

29 es electron-driven proton transfer (EDPT) in Watson-Crick base pairs.

30 dopt anti glycosidic torsion angles and form Watson-Crick base-pairs.

31 pol ternary complex but deviate from normal Watson-Crick base-pairs.

32 ures that are fully determined by underlying Watson-Crick base pairing.

33 hat can recognize complementary sequences by Watson-Crick base pairing.

34 nucleoside analogue that can participate in Watson-Crick base pairing.

35 e lesions because they cannot participate in Watson-Crick base pairing.

36 dye to a specific region of the RNA through Watson-Crick base pairing.

37 to pair with an extended triangle strand by Watson-Crick base pairing.

38 es as a left-handed Z-form double helix with Watson-Crick base pairing.

39 ween hydration of individual nucleotides and Watson-Crick base pairing.

40 ike intermediate and Poleta using the normal Watson-Crick base pairing.

41 predicted to form a stem-loop with standard Watson-Crick base pairing.

42 s that specifically disrupt the Hoogsteen or Watson-Crick base pairing.

43 nicking site]) lacks extensive potential for Watson-Crick base pairing.

44 The strands are held together exclusively by Watson-Crick base pairing.

45 ructure of d(GCGAAAGCT), which does not have Watson-Crick base pairing.

46 5' end of the PPT deviates from traditional Watson-Crick base pairing.

47 taining RNA/DNA hybrid deviate from standard Watson-Crick base pairing.

48 , where optical detection can be achieved by Watson-Crick base pairing.

49 ssemble two individual DNA molecules through Watson-Crick base pairing.

50 that could not be accounted for by classical Watson-Crick base pairing.

51 helix unwinding, and a diminished quality of Watson-Crick base pairing.

52 n complexes to their target nucleic acids by Watson-Crick base pairing.

53 occurrence of both stacking interactions and Watson-Crick base pairing.

54 , which eliminates the need for conventional Watson-Crick base pairing.

55 sDNA, likely due to the competition from the Watson-Crick base pairing.

56 hance RNA stability and increase affinity in Watson-Crick base pairing.

57 dly copy a DNA template according to precise Watson-Crick base pairing.

58 ghly sequence-specific manner through direct Watson-Crick base pairing.

59 Recognition occurs through direct Watson-Crick base-pairing.

60 cognize double-stranded B-DNA through direct Watson-Crick base-pairing.

61 tability supplied to the RNA complex through Watson-Crick base-pairing.

62 old nanoparticle-QD assemblies programmed by Watson-Crick base-pairing.

63 y beyond that which can be achieved based on Watson-Crick base-pairing.

64 :1 motif can be used to distinguish the four Watson.Crick base pairs, a comparable recognition code f

65 ismatch arrangements, but also in a standard Watson-Crick base pair, adopted the same C3'-endo ribose

66 e modified base to participate in a standard Watson-Crick base pairing alignment.

67 within the C2'-endo/C1'-exo range and proper Watson-Crick base pair alignments outside the lesion sit

68 ex are in anti orientation, forming standard Watson-Crick base-pair alignments.

69 at the nanoscale through the specificity of Watson-Crick base pairing, allowing both complex self-as

70 ased on isostericity of Watson-Crick and non-Watson-Crick base pairs, along with the collapsing (hori

71 Non-Watson-Crick base pairs also play crucial roles in terti

72 ored to the 5'-end of the sequence by an A.T Watson-Crick base pair and a potential G.A noncanonical

73 Fpg uses an aromatic wedge to open the Watson-Crick base pair and everts the lesion into its ac

74 deoxynucleoside analogs (xDNA) that maintain Watson-Crick base pairing and base stacking ability; how

75 stent with an overall A-like motif featuring Watson-Crick base pairing and base stacking across the e

76 The 1-MeA lesion impairs Watson-Crick base pairing and blocks normal DNA replicat

77 ith high affinity to single-stranded DNA via Watson-Crick base pairing and can form triple helices vi

78 O4-MeThy may act to destabilize Watson-Crick base pairing and in doing so provide these

79 ugar-phosphate backbones that are capable of Watson-Crick base pairing and in some cases cross-pairin

80 porate dATP opposite the 5' T of the CPD via Watson-Crick base pairing and not by Hoogsteen base pair

81 th Ts of the dimer appears to be mediated by Watson-Crick base pairing and not by Hoogsteen base pair

82 -related strand and each duplex contains six Watson-Crick base pairs and 3'-end adenosine overhangs.

83 MMR must be able to recognize non-Watson-Crick base pairs and excise the misincorporated n

84 discriminate among the four combinations of Watson-Crick base pairs and their orientations at the en

85 astable kissing dimer is formed via standard Watson-Crick base pairs and then converted into a more s

86 They disturb Watson-Crick base-pairing and base-stacking interactions

87 th various combinations of S(2) for atoms in Watson-Crick base-pairs and for two inter-base-pair para

88 ons with a thymine-thymine (T-T) mismatch in Watson-Crick base-pairs and the ligative disassembly of

89 steen trans base pair stacked over a classic Watson-Crick base pair, and a bulge of one or more nucle

90 s may be a common feature of adenines in non-Watson-Crick base pairs, and identify two adenines which

91 with a U1406-U1495 base-pair, a C1407-G1494 Watson-Crick base-pair, and a G1408-A1493 base-pair inst

92 Watson-Crick base pairing appears to play an important r

93 d for a B-type DNA conformation with typical Watson-Crick base pairing are observed along the duplex,

94 hes with other bases (such as GA and AC) and Watson-Crick base pairs are not cleaved by the enzyme.

95 n other RNAs, is presented in which core non-Watson-Crick base pairs are precisely specified.

96 ture, the exchange rates of imino protons in Watson-Crick base pairs are up to 5000-fold lower than t

97 The kinetics of forming a proper Watson-Crick base pair as well incorporating bases oppos

98 esion on the major groove side would utilize Watson-Crick base pairing as indicated by our MD simulat

99 (P1ex), consisting of as little as a single Watson-Crick base pair, as well as the mere presence of

100 ons with p53, the current structures display Watson-Crick base pairs associated with direct or water-

101 base pair configuration that approximates a Watson-Crick base pair at higher pH.

102 solfataricus DNA polymerase 4, which forms a Watson-Crick base pair at the 3' thymine of a dimer but

103 t metal ions, a free 5'-flap (if present), a Watson-Crick base pair at the terminus of the reacting d

104 -side of the cross-link there was a break in Watson-Crick base pairing at base pair X(6).T(17), where

105 ntify and classify modifications that affect Watson-Crick base pairing at three different levels of t

106 oducts at cryptic sites, suggesting that non-Watson-Crick base pairs at the 5' splice site are acting

107 rogen bond alignment as well as by a A22-U40 Watson-Crick base-pair at the junction of stem I.

108 sient sequence-specific excursions away from Watson-Crick base-pairing at CA and TA steps inside cano

109 In vitro assays revealed an active role for Watson-Crick base-pairing at positions 9 and 10 in promo

110 Importantly, no Raman markers of Watson-Crick base pairing, base stacking, or C2'-endo/an

111 Our results indicate an important role for a Watson--Crick base pair between G+1 and C25; this may be

112 orporation was eliminated by disruption of a Watson-Crick base pair between nucleotides 30 and 40 in

113 features: (i) the loop region is closed by a Watson-Crick base pair between Psi1911 and A1919, which

114 e fold, thus providing a platform to promote Watson-Crick base pairing between C9 of the decaloop and

115 Typically, Watson-Crick base pairing between the antisense compound

116 Sequence specificity is provided by Watson-Crick base pairing between the DNA substrate and

117 he binding pocket is stabilized first by the Watson-Crick base pairing between the ligand and Y74, an

118 ciferase gene in cell-free translation using Watson-Crick base pairing between the mRNA and a complem

119 all cases with high 3'-5' regioselectivity, Watson-Crick base pairing between the RNA monomers and t

120 Simulations suggest that the Watson-Crick base-pairing between G8 and C3, the hydroge

121 nucleobase pairs follow standard rules for Watson-Crick base pairing but have rearranged hydrogen b

122 tributes to the selection of correct dNTP by Watson-Crick base pairing, but it cannot explain how low

123 cialized alignment software can also include Watson-Crick base pairs, but none adequately addresses t

124 The discrimination of the four Watson-Crick base pairs by minor groove DNA-binding poly

125 citation of individual guanine-cytosine (GC) Watson-Crick base pairs by ultrafast time-resolved UV/vi

126 triplex structure enhances the stability of Watson-Crick base pairs by up to 5 kcal/mol.

127 the ISL resulting in the formation of a new Watson-Crick base pair (C67 x G80), and disrupts a proto

128 where GCC is replaced by CGG, only a single Watson-Crick base pair can form upon re-pairing when dec

129 This report constitutes evidence that single Watson-Crick base pairs can be identified within individ

130 thermostable (T(m)>90 degrees C), forming 11 Watson-Crick base-pairs capped by a stable ACAA tetraloo

131 The programmability of Watson-Crick base pairing, combined with a decrease in t

132 the new method reproduces better than 90% of Watson-Crick base pairs, comparable with the accuracy of

133 a few of these lonepairs adopt the standard Watson-Crick base-pair conformations, while the majority

134 Watson-Crick base pairing controls the effective molarit

135 of protein-DNA interactions that select for Watson-Crick base pairs correlate with the lowered fidel

136 and free energy calculations suggesting that Watson-Crick base pairing could be employed in poliota f

137 Intermolecular enol tautomers of Watson-Crick base pairs could emerge spontaneously via i

138 his provides a means to distinguish faithful Watson-Crick base-paired DNA from damaged DNA.

139 n the sequence identity of the matched (i.e. Watson-Crick base pair) DNA terminus (template/primer, G

140 forming a two-base overhang (radC) and a six Watson-Crick base-paired duplex.

141 two RNA termini are spatially constrained by Watson-Crick base pairing during the ligation reaction.

142 ndem G.U motifs depends both on the adjacent Watson-Crick base pairs, e.g., 5'G > 5'C, and the sequen

143 ation accuracy, the favored formation of non-Watson-Crick base pairs, efficient mismatch extension, a

144 ut to determine the relationship between non-Watson Crick base-paired elements in the RNA and aminogl

145 ion on the acidities, proton affinities, and Watson-Crick base pairing energies.

146 se to and approximately perpendicular to the Watson-Crick base-pairing faces of two highly conserved

147 modified nucleotide monomers maintained the Watson-Crick base pair fidelity.

148 that form a water-inserted cis Watson-Crick/Watson-Crick base pair flanked by short helices that com

149 base-pairs are very well stacked between the Watson-Crick base-paired flanking bases.

150 irs significantly diminish the importance of Watson-Crick base pairing for the formation of a stable

151 This was evidenced by the disruption of the Watson-Crick base pairing for X(6) x T(17) and A(7) x T(

152 Unexpectedly, only in cases where Watson-Crick base pairs form at the 5'splice site do we

153 ization, positioning its 5'-nucleotide via a Watson-Crick base pair, forming a 3',5'-phosphodiester b

154 a large fraction of the bases engage in non-Watson-Crick base pairing, forming motifs that mediate l

155 t, consistent with stabilization by tertiary Watson-Crick base pairing found in the folded Diels-Alde

156 s underscore the importance of H-bonding and Watson-Crick base pair geometry in the selection of nucl

157 Any deviation from the Watson-Crick base pair geometry was shown to have a dest

158 etween the codon and anticodon, thus sensing Watson-Crick base-pairing geometry and discriminating ag

159 t G*U and U*G wobble pairs separated by four Watson-Crick base pairs has been determined to 2.5 A res

160 nical DNA double helix structure that retain Watson-Crick base-pairing have important roles in DNA re

161 secondary structures displaying noncanonical Watson-Crick base pairing, have recently emerged as key

162 reductions in NMR signal intensities of the Watson-Crick base-paired imino protons and a reduction b

163 The predictable chemistry of Watson-Crick base-pairing imparts a unique structural pr

164 valently bonded base pair that can replace a Watson-Crick base pair in a nucleic acid with minimal di

165 irtually indistinguishable from a canonical, Watson-Crick base pair in double-stranded DNA.

166 e estimate for the free energy change when a Watson-Crick base pair in stem 2 is changed, (2) the loo

167 experiments provided conclusive evidence of Watson-Crick base pairing in alpha PNA-ssDNA hybrids.

168 stabilization even in the face of disrupted Watson-Crick base pairing in S-conformation.

169 loss of local base stacking interactions and Watson-Crick base pairing in the immediate vicinity of t

170 f messenger RNAs (mRNAs) and can involve non-Watson-Crick base pairing in the miRNA seed region.

171 *TA and T*CG triads is comparable to that of Watson-Crick base pairs in canonical triads.

172 y high affinity for AT relative to all other Watson-Crick base pairs in DNA.

173 in the DNA triplex is comparable to that of Watson-Crick base pairs in double-helical DNA.

174 Non-terminal Watson-Crick base pairs in helical stems are experimenta

175 are the most common and highly conserved non-Watson-Crick base pairs in RNA.

176 The results indicate that the stability of Watson-Crick base pairs in the G*TA and T*CG triads is c

177 set of heterocycle pairs to target the four Watson-Crick base pairs in the minor groove of DNA.

178 ide insights into the roles of the other non-Watson-Crick base-pairs in the early stages of unfolding

179 ably well adapted to accommodate the 5'T via Watson-Crick base pairing, in accord with a proposed rol

180 G.U pair showed that replacing G.U by a G.C Watson-Crick base-pair inactivates alanine acceptance by

181 ructure was observed by NMR methods with all Watson-Crick base pairs intact, and the duplex exhibited

182 reveals that G1207 has to disengage from its Watson-Crick base pairing interaction with C1051 in the

183 show that HCV IRES activity requires a 3-nt Watson-Crick base-pairing interaction between the apical

184 ains a pyrimidine residue (Y74) that forms a Watson-Crick base-pairing interaction with the bound pur

185 tural model of loop 6 that specifies all non-Watson-Crick base pair interactions, derived by isosteri

186 ining only DNA components, establishing that Watson-Crick base-pairing interactions alone suffice for

187 used two different means to assemble DNA-NPs-Watson-Crick base-pairing interactions and depletion int

188 mble I) held together via guanosine-cytidine Watson-Crick base-pairing interactions is reported.

189 n and programmable intra- and intermolecular Watson-Crick base-pairing interactions.

190 the D-loop was found to be important since a Watson-Crick base pair introduced at the base of the D-l

191 Formation of a Watson-Crick base pair is accomplished predominantly by

192 er, these observations suggest that a single Watson-Crick base pair is an inadequate model of the pho

193 Since a single Watson-Crick base pair is not stable in solution, RNA po

194 This observation of reverse Watson-Crick base pairing is further supported by therma

195 ) the classical intercalation motif in which Watson-Crick base pairing is intact at the lesion site a

196 NMR data reveal that Watson-Crick base pairing is maintained at both the 5' a

197 ficiency of charge migration through stacked Watson-Crick base pairs is analyzed for coherent hole mo

198 ility to the anchor region through increased Watson-Crick base-pairing is sufficient to impart trans

199 ical studies indicate that the capability of Watson-Crick base-pairing is widespread among potentiall

200 NA junction has B-DNA arms with all standard Watson-Crick base pairs; it therefore represents the int

201 annealed to the plasmid through non-covalent Watson-Crick base-pairing; its removal, therefore, requi

202 and forming a heteroduplex stabilized by 11 Watson-Crick base pairs (K(d) = 0.47 +/- 0.16 microM).

203 The specificity and predictability of Watson-Crick base pairing make DNA a powerful and versat

204 mited by the need to forward-design specific Watson-Crick base pairing manually for any given target

205 estern yellows virus reveals, in addition to Watson-Crick base-pairing, many loop-stem RNA tertiary s

206 This position is not involved in the normal Watson-Crick base pairing needed for specific hybridizat

207 For bulge loops with adjacent Watson-Crick base pairs, neither the identity of the bul

208 e find that whereas hydrogen bonds between a Watson-Crick base pair of template DNA and incoming NTP

209 of nanoparticle arrays and lattices exploit Watson-Crick base pairing of single-stranded DNA sequenc

210 ,N(6)-gamma-HMHP-dA is expected to block the Watson-Crick base pairing of the adducted adenine with t

211 Watson-Crick base pairing of the modified guanine with t

212 Self-assembly of these oligomers by Watson-Crick base pairing of the recognition sequences c

213 The four Watson-Crick base pairs of DNA can be distinguished in t

214 hat gene expression can be controlled by the Watson-Crick base-pairing of small RNAs with messenger R

215 ormational features characteristic of both a Watson-Crick base pair (on the guanine containing strand

216 Of the Watson-Crick base-pairs, only the 5'-terminal pair of st

217 nucleotide is bound in either the canonical Watson-Crick base pair or a nonplanar base pair.

218 one dNTP in excess drives formation of a non-Watson-Crick base pair or if it forces replicative DNA c

219 equally well control substrates with either Watson-Crick base pairs or mismatched substrates with no

220 es mismatch repair with recognition of a non-Watson-Crick base-pair or base insertion/deletion site i

221 Formation of either a Watson-Crick base-pair or G.U pair between positions 688

222 but also causes the enzyme to favor faithful Watson-Crick base pairing over mutagenic configurations.

223 s for insertion of nucleotides that can form Watson-Crick base pairs parallel those for the Klenow fr

224 rising nucleotides that interact through non-Watson-Crick base pairing play critical roles in RNA fun

225 ructures form recurrent 3D motifs, where non-Watson-Crick base pairs play a central role.

226 of the base pair; intercalators that bind to Watson-Crick base pairs promote the polymerization of ol

227 To maintain the correct Watson-Crick base pairing properties of the wobble base

228 ecificity is determined by the nature of the Watson-Crick base-pairing region of the NTP base and the

229 Watson-Crick base pairing remained intact throughout the

230 Mismatched (non-Watson-Crick) base pairs represent the most common type

231 -rich PNAs can hybridize by the formation of Watson-Crick base pairs, resulting in hybrid PNA-RNA dup

232 to the mutant sites of duplex DNA under the Watson-Crick base pairing rule.

233 We show that human Pol(iota) violates the Watson-Crick base-pairing rule opposite template T.

234 any biological source synthesize DNA by the Watson-Crick base-pairing rule, incorporating A, G, C, a

235 erases must select nucleotides that preserve Watson-Crick base pairing rules and choose substrates wi

236 Structural DNA nanotechnology relies on Watson-Crick base pairing rules to assemble DNA motifs i

237 ming duplex structures with DNA according to Watson-Crick base pairing rules, but contains a N-(2-ami

238 f the knowledge of helical DNA structure and Watson-Crick base pairing rules, scientists have constru

239 Meanwhile, nucleic acid probes based on Watson-Crick base-pairing rules are also being widely ap

240 A polymerase I (Klenow fragment) to preserve Watson-Crick base-pairing rules.

241 The standard Watson-Crick base-pairing scheme, retained in the T:A an

242 regions and employ both Watson-Crick and non-Watson-Crick base-pairing, screening of candidate binder

243 hod recapitulates more than one-third of non-Watson-Crick base pairs seen in the native structures.

244 RNA molecule and the disruption it causes to Watson-Crick base pairing should be considered when asse

245 Thus, polyamides designed to target Watson-Crick base pairs should utilize the strength of -

246 Watson-Crick base-pairing slows the rate of vibrational

247 G mismatches were examined and compared with Watson-Crick base-pair stabilities.

248 plays an underappreciated role in modulating Watson-Crick base pairing strength and potentially pi-pi

249 ase III[DeltadsRBD] is sensitive to specific Watson-Crick base-pair substitutions which also inhibit

250 uilding blocks are found to be much stronger Watson-Crick base-pairing systems than RNA.

251 tiCG, antiTA, and antiAT with respect to the Watson-Crick base pair targets that they bind.

252 Although m(6)A does not preclude Watson-Crick base pairing, the N(6)-methyl group alters

253 nt end duplex with two a+.c mispairs and six Watson-Crick base-pairs, the strands in the duplex slide

254 fers C/G base pairs (>10 times) to the other Watson-Crick base pairs; therefore, f/Im behaves like th

255 Both duplexes are standard A form, with Watson-Crick base pairing throughout.

256 cleotide analogues that mimic the shape of a Watson-Crick base pair to investigate the kinetic conseq

257 mplete purine ring that allows the canonical Watson-Crick base pairing to be maintained.

258 in how low-fidelity DNA polymerases overcome Watson-Crick base pairing to catalyze non-Watson-Crick d

259 ained when adenine and thymine bases undergo Watson-Crick base pairing to form a double helix.

260 e use of isostericity matrix analysis of non-Watson-Crick base pairing to rationalize mutagenesis of

261 copies of any nucleic acid without impairing Watson-Crick base pairing to short probes would eliminat

262 e unique geometry of canonical G.C and A.T/U Watson-Crick base pairs to discriminate against DNA and

263 on at the nanoscale can be achieved by using Watson-Crick base-pairing to direct the assembly and ope

264 ' (A.T and G.C) and 'inverted' (T.A and C.G) Watson-Crick base pairs, using UV melting profiles to as

265 Watson-Crick base pairing was conserved at the S-cdG.dC

266 Without the requirement of specific Watson-Crick base-pairing, we obtained discrete, free-st

267 as the cytosine amino protons of all of the Watson-Crick base pairs were assigned.

268 icities of Im, Py, Hp, and beta for the four Watson.Crick base pairs were determined for two polyamid

269 es formation of one Watson-Crick and two non-Watson-Crick base pairs, which facilitate generation of

270 o form a bisPNA in which one strand binds by Watson-Crick base pairing while the other binds by Hoogs

271 idues G1-G2-C3-G4 and C6-U7 forming standard Watson Crick base-pairs with self-complementary residues

272 When psi forms a Watson-Crick base pair with adenine in an RNA helix, NH1

273 vivo due to its anti-conformation forming a Watson-Crick base pair with correct deoxycytidine 5'-tri

274 y assumed that 7-deazaguanine forms a normal Watson-Crick base pair with cytosine, detailed thermodyn

275 ne such modification is the formation of the Watson-Crick base pair with cytosine, which is reported

276 nalysis reveals that Fm7dG forms a canonical Watson-Crick base pair with dCTP, but metal ion coordina

277 Moreover, dCTP forms a Watson-Crick base pair with dG, two nucleotides upstream

278 ed only upon addition of dCTP, which forms a Watson-Crick base pair with template dG and not during m

279 that, whereas the 3' T of the dimer forms a Watson-Crick base pair with the incoming dideoxy ATP, th

280 The 3' thymine of the CPD forms a Watson-Crick base pair with the incoming dideoxyATP, but

281 ating Tg is intrahelical and forms a regular Watson-Crick base pair with the incorporated A.

282 rating the nucleotide that forms the correct Watson-Crick base pair with the template base.

283 a-2-oxo-phenothiazine, tCfTP) that maintains Watson-Crick base pairing with guanine.

284 tes within the active site in the absence of Watson-Crick base pairing with template and mapped movem

285 t the 3' ss is mainly recognized through non-Watson-Crick base pairing with the 5' ss and branch poin

286 ture, BrG adopts anti conformation and forms Watson-Crick base pairing with the incoming dCTP analog.

287 tion, both guanines of the Pt-GG lesion form Watson-Crick base pairing with the primer terminus dC an

288 Such Watson-Crick base pairing with tRNA has been observed in

289 due to the ability of 8-oxoG to form stable Watson-Crick base pairs with deoxycytidine (8-oxoG:dC) a

290 (tC) is a fluorescent nucleotide that forms Watson-Crick base pairs with dG.

291 hirality are incapable of forming contiguous Watson-Crick base pairs with each other-has enforced a "

292 of residues 697-699 involved in the proposed Watson-Crick base pairs with stem-loop I.

293 he extended single-stranded oligomers formed Watson-Crick base pairs with the dangling end of the dup

294 eferentially inserts ribonucleotides forming Watson-Crick base pairs with the DNA template >200-fold

295 omal P site, bases C74 and C75 of tRNA, form Watson-Crick base-pairs with G2252 and G2251, respective

296 T. thermophilus Kt-23 has two further non-Watson-Crick base pairs within the non-canonical helix,

297 ole (Hz/Bi) pairs for each of the respective Watson-Crick base pairs within the sequence context 5'-T

298 sion of the two phosphate backbones, forcing Watson-Crick base-pairs within the duplex to flip outwar

299 AlkD distort the DNA backbone to detect non-Watson-Crick base pairs without duplex intercalation.

300 Non-Watson-Crick base pairs would lead to mutations.