ライフサイエンスコーパス: Yersinia

1 data and analysis tools for the analysis of Yersinia.

2 iaTree for constructing phylogenetic tree of Yersinia.

3 the function of the pathogenic machinery in Yersinia.

4 lling the host colonization and virulence of Yersinia.

5 Gram-negative bacterial pathogens, including Yersinia.

6 sphatase, is essential for full virulence of Yersinia.

7 spiratory electron acceptor tetrathionate by Yersinia.

8 pe III secretion system (T3SS) of pathogenic Yersinia.

9 bacter: 738, Salmonella: 624, Shigella: 376, Yersinia: 17) were identified and followed for a median

10 HEV (Mikrogen) or the ELISA test kit pigtype Yersinia Ab (Qiagen), respectively.

11 initially low-affinity antibacterial (e.g., Yersinia) Abs cross-reactive with TSHR, eventually leadi

12 Yersinia adhesin A (YadA) belongs to a class of bacteria

13 YscO is required for T3S in Yersinia and is known to interact with several other T3S

14 avirulent strains of Gram-negative bacteria, Yersinia and Klebsiella, and less so by their wild-type

15 compartment showed extreme susceptibility to Yersinia and were deficient in monocyte and neutrophil-d

16 luding enteric Escherichia coli, Salmonella, Yersinia, and Shigella, to subvert cell signaling and ho

17 Using Yersinia as a surrogate host, we demonstrated that many

18 Yersinia bacteria cause a range of human diseases, inclu

19 Pathogenic Yersinia bacteria cause a range of human diseases.

20 Pathogenic Yersinia bacteria inject effector proteins termed Yops,

21 crystal structure of the Anbu particle from Yersinia bercovieri (YbAnbu).

22 ronic inflammation, which persist long after Yersinia clearence.

23 tion system, whereas the delivery of GBP2 to Yersinia-containing vacuoles (YCVs) requires hypersecret

24 nded DNA (dsDNA) to a type I-F CRISPR system yersinia (Csy) surveillance complex leads to large quate

25 of Rac1 but not of RhoA, -B, or -C inhibited Yersinia effector translocation in CNF-Y-treated and con

26 During infection, Yersinia employs two virulence factors, YopE and YopH, t

27 tably Aeromonas sp. (23.8%) by FilmArray and Yersinia enterocolitica (48.1%) by the Luminex assay.

28 ed defective clearance of the ileal pathogen Yersinia enterocolitica and an elevated inflammatory cyt

29 ) spp., Shigella spp., Campylobacter spp. or Yersinia enterocolitica and matched each with up to 4 un

30 Escherichia coli, Yersinia enterocolitica and Salmonella enterica serovar

31 pe stress response required for virulence in Yersinia enterocolitica and Salmonella enterica.

32 ent the first three-dimensional structure of Yersinia enterocolitica and Shigella flexneri injectisom

33 rrelation spectroscopy, we show that in live Yersinia enterocolitica bacteria these soluble proteins

34 Yersinia enterocolitica biovar 1B employs two type three

35 Infection with Yersinia enterocolitica causes acute diarrhea in early c

36 The enteropathogenic bacterium Yersinia enterocolitica deactivates TLR-induced signalin

37 e III secretion system of the human pathogen Yersinia enterocolitica enabled efficient identification

38 t an aberrant acute inflammatory response to Yersinia enterocolitica infection leads to long-lasting

39 Yersinia enterocolitica is an enteropathogenic bacterium

40 Yersinia enterocolitica is typically considered an extra

41 gainst siderophilic extracellular pathogens (Yersinia enterocolitica O9) by controlling non-transferr

42 conjugation-ready tetrasaccharide of O-PS of Yersinia enterocolitica O:50 strain 3229 and the trisacc

43 YapE orthologues but is not conserved in the Yersinia enterocolitica protein.

44 chaperone in the physiology and virulence of Yersinia enterocolitica serotype O:3.

45 The highly pathogenic Yersinia enterocolitica strains have a chromosomally enc

46 er Yersinia species, and differences between Yersinia enterocolitica subsp. enterocolitica and Yersin

47 nia enterocolitica subsp. enterocolitica and Yersinia enterocolitica subsp. palearctica.

48 rophomonas maltophilia, Vibrio cholerae, and Yersinia enterocolitica T2S-expressing plant pathogens i

49 ins, fused to the N-terminal fragment of the Yersinia enterocolitica T3S substrate YopE, are effectiv

50 btype the important human-pathogenic species Yersinia enterocolitica to whole-genome resolution level

51 Yersinia enterocolitica type III secretion machines tran

52 , Bacillus cereus was the most sensitive and Yersinia enterocolitica was found to be the most resista

53 We report the MgADP structure of Yersinia enterocolitica YopO in complex with actin, whic

54 , is composed of ~22 copies of SctQ (YscQ in Yersinia enterocolitica), which require the presence of

55 We find that IECs infected with Yersinia enterocolitica, an enteric pathogen, use beta1

56 41, norovirus, rotavirus A, Vibrio cholerae, Yersinia enterocolitica, Entamoeba histolytica, Cryptosp

57 lmonella spp., Vibrio spp., Vibrio cholerae, Yersinia enterocolitica, enteroaggregative E. coli, ente

58 eserved stool specimens for the detection of Yersinia enterocolitica, enterotoxigenic Escherichia col

59 lence of a Gram-negative bacterial pathogen, Yersinia enterocolitica, when subjected to low temperatu

60 Staphylococcus aureus, Escherichia coli and Yersinia enterocolitica--demonstrated that the zone of i

61 re that CNF-Y increases Yop translocation in Yersinia enterocolitica-infected cells up to 5-fold.

62 olic flagellin of Salmonella Typhimurium and Yersinia enterocolitica.

63 causes plague, Yersinia pseudotuberculosis, Yersinia enterocolitica.

64 ighly resistant to orogastric infection with Yersinia enterocolitica.

65 Staphylococcus aureus, Escherichia coli and Yersinia enterocolitica.

66 ute to pathogenesis, including the bacterium Yersinia enterocolitica.

67 reus, Bacillus cereus, Escherichia coli, and Yersinia enterocolitica.

68 cute enteric infection by the proteobacteria Yersinia enterocolitica.

69 acilitate the ongoing and future research of Yersinia, especially those generally considered non-path

70 comparative genomics, and investigations of Yersinia-flea interactions have disclosed the important

71 ved two structures of an ASBT homologue from Yersinia frederiksenii (ASBTYf) in a lipid environment,

72 Pathogenic bacteria such as Listeria and Yersinia gain initial entry by binding to host target ce

73 Comparison of Yersinia genomes revealed that DNA encoding YapV or each

74 T) for comparative pathogenomics analysis of Yersinia genomes; (3) YersiniaTree for constructing phyl

75 and analysis platform is needed to hold the Yersinia genomic data and analysis tools for the Yersini

76 ialized platform to hold the rapidly-growing Yersinia genomic data and to provide analysis tools part

77 ce and analysis platform for the analysis of Yersinia genomic data.

78 on of sRNAs to the regulation of the T3SS in Yersinia has been largely unstudied, however.

79 The genus Yersinia has been used as a model system to study pathog

80 in sequencing technologies, many genomes of Yersinia have been sequenced.

81 ociated with urinary E. coli isolates is the Yersinia high pathogenicity island (HPI), which directs

82 The Yersinia high-pathogenicity island (HPI) is common to mu

83 zation interface of PcrH mirrors that of the Yersinia homolog SycD and not the dimerization interface

84 vo, suggesting that cell death promotes anti-Yersinia host defense.

85 and other Enterobacteriaceae expressing the Yersinia HPI also secrete escherichelin, a second metall

86 e escherichelin biosynthetic capacity of the Yersinia HPI while eliminating the Ybt biosynthetic capa

87 fect may relate to the apparent selection of Yersinia HPI-positive E. coli in uncomplicated clinical

88 The screening for anti-Yersinia IgG resulted in 86% positive findings using the

89 s platform MCR 3 to detect anti-HEV and anti-Yersinia IgG.

90 of immune signaling by YopJ to promote anti-Yersinia immune defense.

91 ses play an important role in promoting anti-Yersinia immune defense.

92 unity." The Gram-negative bacterial pathogen Yersinia inactivates critical proteins of the NF-kappaB

93 Pathogenic Yersinia, including Y. pestis, the agent of plague in hu

94 PK1-dependent cell death, we now reveal that Yersinia-induced apoptosis is critical for host survival

95 In this article, we show that Yersinia-induced apoptosis of human macrophages involves

96 Yersinia-induced apoptosis requires the kinase activity

97 3 and caspase-8 or FADD completely abrogated Yersinia-induced cell death and caspase-1 activation.

98 ticle, we report a key role for TNF/TNFR1 in Yersinia-induced cell death of murine macrophages, which

99 R4/TRIF-independent pathways in the death of Yersinia-infected cells.

100 In turn,Yersinia-infected macrophages respond to translocation o

101 he processing of MyD88 was not restricted to Yersinia infection and to proapoptotic Toll-IL-1R domain

102 Nevertheless, Yersinia infection induces inflammatory responses in viv

103 e cells, and were attenuated in disseminated Yersinia infection.

104 nt mice displayed enhanced susceptibility to Yersinia infection.

105 itu and the first structural analysis of the Yersinia injectisome.

106 Yersinia is a Gram-negative bacteria that includes serio

107 The genus Yersinia is a large and diverse bacterial genus consisti

108 accurate and reproducible identification of Yersinia isolates to the species level, a process often

109 ucture of the CdiA-CT/CdiIYkris complex from Yersinia kristensenii ATCC 33638.

110 e of NF-kappaB and MAPK signaling imposed by Yersinia on infected cells.

111 ichia, Salmonella, Klebsiella, Shigella, and Yersinia opportunistic pathogens, the structure of GusR

112 Here we show that YmoB, the Yersinia orthologue of TomB, and its single cysteine var

113 antigens (rAgs) of HEV genotypes 1 and 3 and Yersinia outer protein D (YopD) on a flow-through chemil

114 The Yersinia outer protein J (YopJ) family of bacterial effe

115 The Yersinia outer protein J (YopJ) family of T3Es is a wide

116 dent upon type III secretion system effector Yersinia outer protein J (YopJ), is minimally affected b

117 de host immune defences through injection of Yersinia outer proteins (Yops) into phagocytic cells.

118 These effectors, termed Yersinia outer proteins (Yops), modulate multiple host s

119 an injectisome and effector proteins, called Yersinia outer proteins (Yops), that modulate activation

120 responses in infected macrophages to promote Yersinia pathogenesis.

121 Here we demonstrate that when Yersinia pesitis is grown in laboratory media, peptides

122 a) in a 19th century intestinal specimen and Yersinia pestis ("Black Death" plague) in a medieval too

123 Yersinia pestis (the plague bacillus) and its ancestor,

124 s from cultures of two attenuated strains of Yersinia pestis [KIM D27 (pgm-) and KIM D1 (lcr-)] grown

125 Here we studied the interaction between the Yersinia pestis ABC heme importer (HmuUV) and its partne

126 Yersinia pestis adopts a unique life stage in the digest

127 specially potential bioterrorism agents like Yersinia pestis and Bacillus anthracis which feature on

128 of the same species, including 5 strains of Yersinia pestis and Bacillus anthracis.

129 tant of 20 nM between EGFP-labeled LcrV from Yersinia pestis and its cognate membrane-bound protein Y

130 tant to pigmentation locus-negative (pgm(-)) Yersinia pestis and that this phenotype maps to a 30-cen

131 s both the protective F1 capsular antigen of Yersinia pestis and the LcrV protein required for secret

132 e identification of new virulence factors in Yersinia pestis and understanding their molecular mechan

133 owed differences in virulence genes found in Yersinia pestis and Yersinia pseudotuberculosis compared

134 nt of YopJ-dependent cytotoxicity induced by Yersinia pestis and Yersinia pseudotuberculosis paradoxi

135 ion of either Yersinia pseudotuberculosis or Yersinia pestis bacteria express the small RNAs YSR35 or

136 molecule cyclic diguanylate is essential for Yersinia pestis biofilm formation that is important for

137 The 14th-18th century pandemic of Yersinia pestis caused devastating disease outbreaks in

138 Yersinia pestis causes bubonic plague, a fulminant disea

139 Yersinia pestis causes bubonic, pneumonic, and septicemi

140 The Gram-negative bacterium Yersinia pestis causes plague, a rapidly progressing and

141 Yersinia pestis causes the fatal respiratory disease pne

142 Braun lipoprotein (Lpp) and MsbB attenuated Yersinia pestis CO92 in mouse and rat models of bubonic

143 The pH 6 antigen (Psa) of Yersinia pestis consists of fimbriae that bind to two re

144 ts the most severe form of disease caused by Yersinia pestis due to its ease of transmission, rapid p

145 Yersinia pestis has caused at least three human plague p

146 Because Yersinia pestis HasA (HasA(yp)) presents a Gln at positi

147 ere, we report the oldest direct evidence of Yersinia pestis identified by ancient DNA in human teeth

148 tudies (influenza A in lesser snow geese and Yersinia pestis in coyotes), we argue that with careful

149 ery that regulates the entry and survival of Yersinia pestis in host macrophages is poorly understood

150 ated with iron(III)-yersiniabactin import in Yersinia pestis In this study, we compared the impact of

151 responses of C57BL/6 and SEG MPs exposed to Yersinia pestis in vitro were examined.

152 n lymph nodes (LNs), or buboes, characterize Yersinia pestis infection, yet how they form and functio

153 Yersinia pestis is a Gram-negative bacterium that is the

154 Yersinia pestis is a tier 1 agent due to its contagious

155 Yersinia pestis is an arthropod-borne bacterial pathogen

156 This frenzied inflammatory response to Yersinia pestis is poorly understood.

157 Yersinia pestis is the causative agent of bubonic and pn

158 Yersinia pestis is the causative agent of plague.

159 The bacteria Yersinia pestis is the etiological agent of plague and h

160 The plague bacillus Yersinia pestis is unique among the pathogenic Enterobac

161 We report that Yersinia pestis LcrF binds to and activates transcriptio

162 nst His-tagged influenza hemagglutinin 5 and Yersinia pestis LcrV antigens.

163 We find the origins of the Yersinia pestis lineage to be at least two times older t

164 n are broadly used in many fields, including Yersinia pestis pathogenesis.

165 rate chain to the 2' position of lipid A, in Yersinia pestis produced bisphosphoryl hexa-acylated lip

166 Inhalation of the bacterium Yersinia pestis results in primary pneumonic plague.

167 roinflammatory responses through TLRs by the Yersinia pestis T3S needle protein, YscF, the Salmonella

168 In Yersinia pestis the autotransporter YapE has adhesive pr

169 mal system for interrogating such couplings: Yersinia pestis transmission exerts intense selective pr

170 the possible role of Na(+)/H(+) antiport in Yersinia pestis virulence and found that Y. pestis strai

171 .3, raised to the LcrV virulence factor from Yersinia pestis were characterised for their Fab affinit

172 HSL synthases: Burkholderia mallei BmaI1 and Yersinia pestis YspI.

173 flammatory response induced by other lethal (Yersinia pestis) and non-lethal (Legionella pneumophila,

174 cessfully produce disease, the causal agent (Yersinia pestis) must rapidly sense and respond to rapid

175 a and Salmonella enterica serovar Typhi, and Yersinia pestis), and 3 protozoa (Leishmania spp., Plasm

176 ymerization of a single protein, e.g., YscF (Yersinia pestis), PscF (Pseudomonas aeruginosa), PrgI (S

177 n, the serine/threonine kinase YopO (YpkA in Yersinia pestis), uses monomeric actin as bait to recrui

178 trophic European Black Death/bubonic plague (Yersinia pestis).

179 Plague is initiated by Yersinia pestis, a highly virulent bacterial pathogen.

180 he consequence of a singular introduction of Yersinia pestis, after which the disease established its

181 rofloxacin resistance in Bacillus anthracis, Yersinia pestis, and Francisella tularensis.

182 een host-pathogen interactions of B. mallei, Yersinia pestis, and Salmonella enterica.

183 acids from BT organisms (Bacillus anthracis, Yersinia pestis, Francisella tularensis, Brucella spp.,

184 -six distinct strains of Bacillus anthracis, Yersinia pestis, Francisella tularensis, Burkholderia ma

185 ns cause host cell death upon infection, and Yersinia pestis, infamous for its role in large pandemic

186 ns, particularly the N terminus of YscF from Yersinia pestis, influences host immune responses.

187 Here we show that in Yersinia pestis, irp2, a gene encoding the synthetase (H

188 lague, caused by the Gram-negative bacterium Yersinia pestis, is favored by a robust early innate imm

189 biothreat agents such as Bacillus anthracis, Yersinia pestis, or Burkholderia pseudomallei Convention

190 The etiologic agent of bubonic plague, Yersinia pestis, senses self-produced, secreted chemical

191 r gene products are functional receptors for Yersinia pestis, the agent of plague, as shown by overex

192 The arthropod-borne transmission route of Yersinia pestis, the bacterial agent of plague, is a rec

193 ly, there is no FDA-approved vaccine against Yersinia pestis, the causative agent of bubonic and pneu

194 Yersinia pestis, the causative agent of plague, binds ho

195 Yersinia pestis, the causative agent of plague, expresse

196 hat distinguish DNA amplicons generated from Yersinia pestis, the causative agent of plague, from the

197 For transmission to new hosts, Yersinia pestis, the causative agent of plague, replicat

198 Yersinia pestis, the causative agent of plague, uses a t

199 Yersinia pestis, the causative agent of plague, utilizes

200 nd F1-V, a candidate recombinant antigen for Yersinia pestis, the causative agent of plague.

201 m (T3SS) is essential in the pathogenesis of Yersinia pestis, the causative agent of plague.

202 f essential gene prediction in the bacterium Yersinia pestis, the causative agent of plague.

203 mical characterization of the AI-2 system in Yersinia pestis, the causative agent of plague.

204 Yersinia pestis, the etiologic agent of plague, is a bac

205 9 (TLR9) agonist, confers protection against Yersinia pestis, the etiologic agent of plague.

206 that includes serious pathogens such as the Yersinia pestis, which causes plague, Yersinia pseudotub

207 ncient plague strains are basal to all known Yersinia pestis.

208 genome sequences, of which the majority are Yersinia pestis.

209 ue is a deadly respiratory disease caused by Yersinia pestis.

210 ement for Hfq in the closely related species Yersinia pestis.

211 including Salmonella, Escherichia, Shigella, Yersinia, Pseudomonas, and Chlamydia spp.

212 stis (the plague bacillus) and its ancestor, Yersinia pseudotuberculosis (which causes self-limited b

213 elated food- and waterborne enteric pathogen Yersinia pseudotuberculosis A combination of population

214 secreted in a type III-dependent manner from Yersinia pseudotuberculosis and also secreted from C. tr

215 Enteric pathogens such as Yersinia pseudotuberculosis and enteropathogenic Escheri

216 structures, we mapped the RNA structurome of Yersinia pseudotuberculosis at three different temperatu

217 and core metabolism in the enteric pathogen Yersinia pseudotuberculosis by integrated transcriptome

218 virulence genes found in Yersinia pestis and Yersinia pseudotuberculosis compared to other Yersinia s

219 lymph nodes and associated lymphatics after Yersinia pseudotuberculosis infection and clearance.

220 esponses within SLOs during gastrointestinal Yersinia pseudotuberculosis infection to limit pathogen

221 vated with lipopolysaccharide (LPS) prior to Yersinia pseudotuberculosis infection, caspase-1 is acti

222 In a mouse model of Yersinia pseudotuberculosis infection, we show that at l

223 ensal microbiota or animal susceptibility to Yersinia pseudotuberculosis infection.

224 We demonstrate that, in addition to MyD88, Yersinia pseudotuberculosis inhibits TRIF signaling thro

225 Yersinia pseudotuberculosis is a foodborne pathogenic ba

226 To test these models, we constructed a Yersinia pseudotuberculosis mutant expressing YopD devoi

227 Here, we constructed a Yersinia pseudotuberculosis mutant strain with arabinose

228 e found that only a small fraction of either Yersinia pseudotuberculosis or Yersinia pestis bacteria

229 cytotoxicity induced by Yersinia pestis and Yersinia pseudotuberculosis paradoxically leads to decre

230 itating biofilm on Caenorhabditis elegans by Yersinia pseudotuberculosis represents a tractable model

231 have suggested that rfaH may be required for Yersinia pseudotuberculosis resistance to antimicrobial

232 We report that oral infection with Yersinia pseudotuberculosis results in the development o

233 ium evolved from an ancestral enteroinvasive Yersinia pseudotuberculosis strain by gene loss and acqu

234 YscU is a Yersinia pseudotuberculosis type III secretion system pr

235 itor identified by in vitro screening, using Yersinia pseudotuberculosis Using a mouse model of P. ae

236 iI complexes from Escherichia coli EC869 and Yersinia pseudotuberculosis YPIII to explore the evoluti

237 nal peptide generated by auto-proteolysis of Yersinia pseudotuberculosis YscU, is secreted by the T3S

238 acterial pathogen that evolved recently from Yersinia pseudotuberculosis, an enteric pathogen transmi

239 Following clearance of Yersinia pseudotuberculosis, sustained inflammation and

240 Yersinia pseudotuberculosis, the closely related food-an

241 as the Yersinia pestis, which causes plague, Yersinia pseudotuberculosis, Yersinia enterocolitica.

242 Using this tool for Yersinia pseudotuberculosis-infected lymphatic tissues,

243 uring primary infection of C57BL/6 mice with Yersinia pseudotuberculosis.

244 of the T3SS in the gastrointestinal pathogen Yersinia pseudotuberculosis.

245 haracterize modified peptide-cytidylate from Yersinia pseudotuberculosis.

246 Salmonella enterica serovar Typhimurium and Yersinia pseudotuberculosis.

247 s cell death mediates immune defense against Yersinia remain poorly defined.

248 eature of T3SA, as an effectorless strain of Yersinia remains confined to phagosomes.

249 inia genomic data and analysis tools for the Yersinia research community.

250 the YersiniaBase, a robust and user-friendly Yersinia resource and analysis platform for the analysis

251 rm is the use of the Csy-type (CRISPR system yersinia) ribonuclease 4 (Csy4) and tRNA processing enzy

252 Here we studied Yersinia ruckeri antifeeding prophage 18 (Afp18), the to

253 oyed by many pathogens, including the genera Yersinia, Shigella, Pseudomonas, and Salmonella, to deli

254 Yersinia species cause zoonotic infections, including en

255 Pathogenic Yersinia species employ several strategies to evade the

256 The YopJ protein of pathogenic Yersinia species inhibits NF-kappaB and MAPK signaling,

257 t contrary to hypotheses that all pathogenic Yersinia species share a recent common pathogenic ancest

258 Pathogenic Yersinia species utilize a type III secretion system to

259 ersinia pseudotuberculosis compared to other Yersinia species, and differences between Yersinia enter

260 E occurs in Y. pestis but not in the enteric Yersinia species, and requires the omptin Pla (plasminog

261 tical virulence component for the pathogenic Yersinia species, and the regulation of this system is t

262 Using whole-genome sequencing of all Yersinia species, we delineate the gene complement of th

263 tial virulence factor produced by pathogenic Yersinia species.

264 that is secreted into host cells infected by Yersinia species.

265 We identified a Yersinia-specific sRNA, Ysr141, carried by the T3SS plas

266 Some Yersinia spp. also secrete the Rho protein activator cyt

267 ulation, while its similarity with yscW from Yersinia spp. argued in favor of a role in machinery ass

268 ncoded type three secretion system (TTSS) of Yersinia spp. is responsible for the delivery of effecto

269 hepatitis E virus (HEV) and enteropathogenic Yersinia spp. were analyzed in parallel using immobilize

270 Vibrio spp., Salmonella spp., Shigella spp., Yersinia spp., Citrobacter spp., enterotoxigenic (ETEC)

271 itors of type III secretion system (T3SS) in Yersinia spp., have an inhibitory effect on chlamydial i

272 ence of YopE, YopT, or YopO in the infecting Yersinia strain, indicating that none of the Yops report

273 However, some non-pestis Yersinia strains and Enterobacteriaceae did elicit signa

274 quence typing-based scheme that can identify Yersinia strains to the species level to a level of reso

275 In summary, the CNF-Y activity of Yersinia strongly enhances Yop translocation through act

276 PLCgamma2 signaling hubs may be critical for Yersinia survival.

277 & Microbe, Chung et al. (2016) show that the Yersinia T3SS effector protein YopM counteracts this rec

278 Three models describe how the Yersinia T3SS might trigger inflammation: (i) mammalian

279 Mammalian cells recognize the Yersinia T3SS, leading to a host response that includes

280 In Yersinia, the switch to secretion of effector proteins i

281 In pathogenic Yersinia, the T3SS pore-forming proteins are YopB and Yo

282 n of effectors into mammalian cells requires Yersinia to both insert a translocon into the host cell

283 e sites may be a strategy used by pathogenic Yersinia to prevent inactivation of this important virul

284 which the initial attachment/recognition of Yersinia to/by C. elegans is followed by bacterial growt

285 The Yersinia translocation regulatory protein YopK promotes

286 r findings indicate that lysosomal damage by Yersinia translocon proteins promotes inflammasome activ

287 g vacuoles (YCVs) requires hypersecretion of Yersinia translocon proteins.

288 aperone LcrH are essential components of the Yersinia type III pathway, enabling effector translocati

289 The Yersinia type III secretion system (T3SS) translocates Y

290 Yersinia up-regulates the gene and expression dose of th

291 In this study, we identify the Yersinia urease enzyme as the responsible oral toxin.

292 ells, thereby limiting cellular detection of Yersinia virulence activity.

293 Identifying molecular targets of Yersinia virulence effectors, or Yops, during animal inf

294 ckade of NF-kappaB and MAPK signaling by the Yersinia virulence factor YopJ inhibits cytokine product

295 bust effector Yop function, is important for Yersinia virulence.

296 -1 in activated macrophages and in promoting Yersinia virulence.

297 e to host defense peptides, and virulence of Yersinia, we constructed DeltarfaH mutants of Y. pseudot

298 to express the invasin surface receptor from Yersinia, which enables uptake via mammalian host beta1-

299 esigned to interfere with internalization of Yersinia without disturbing endocytosis.

300 SptP), which shares structural homology with Yersinia YopH.