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1 trophic European Black Death/bubonic plague (Yersinia pestis).
2 formational stability of the chaperone LcrH (Yersinia pestis).
3 om the genome of the closely related species Yersinia pestis.
4 oding putative c-di-GMP metabolic enzymes in Yersinia pestis.
5 -encoded type III secretion system (T3SS) of Yersinia pestis.
6 tes, obesity, and infection by the bacterium Yersinia pestis.
7 rulence protein YopM of the plague bacterium Yersinia pestis.
8 in human history, is caused by the bacterium Yersinia pestis.
9 ics against the potential bioterrorism agent Yersinia pestis.
10 nto eukaryotic cells by the plague bacterium Yersinia pestis.
11 tions, is transmitted by fleas infected with Yersinia pestis.
12 re resistant to several pathogens, including Yersinia pestis.
13 nctioning in Yersinia pseudotuberculosis and Yersinia pestis.
14 hilum, and five (2.7%) were seropositive for Yersinia pestis.
15 Salmonella spp., Yersinia enterocolitica and Yersinia pestis.
16 the phosphatase YopH, a bacterial toxin from Yersinia pestis.
17 cterial pathogens Listeria monocytogenes and Yersinia pestis.
18 responses that occur following inhalation of Yersinia pestis.
19 ts from pulmonary infection by the bacterium Yersinia pestis.
20 ncient plague strains are basal to all known Yersinia pestis.
21 genome sequences, of which the majority are Yersinia pestis.
22 ue is a deadly respiratory disease caused by Yersinia pestis.
23 ement for Hfq in the closely related species Yersinia pestis.
26 Here we studied the interaction between the Yersinia pestis ABC heme importer (HmuUV) and its partne
29 he consequence of a singular introduction of Yersinia pestis, after which the disease established its
30 oximately 150 in silico DNA fingerprints for Yersinia pestis and 250 fingerprints for Francisella tul
31 specially potential bioterrorism agents like Yersinia pestis and Bacillus anthracis which feature on
33 the strictly conserved glycine to serine in Yersinia pestis and Escherichia coli topoisomerase I res
35 ly or intratracheally with the F1 antigen of Yersinia pestis and flagellin exhibited dramatic increas
36 tant of 20 nM between EGFP-labeled LcrV from Yersinia pestis and its cognate membrane-bound protein Y
38 shared approximately 70-kb plasmids (pCD in Yersinia pestis and pYV in enteropathogenic Yersinia pse
39 he cell surface of both Escherichia coli and Yersinia pestis and show that a subset of these proteins
40 o systemic infection with the KIM5 strain of Yersinia pestis and that B10.T(6R) mice become susceptib
41 tant to pigmentation locus-negative (pgm(-)) Yersinia pestis and that this phenotype maps to a 30-cen
42 s both the protective F1 capsular antigen of Yersinia pestis and the LcrV protein required for secret
43 e identification of new virulence factors in Yersinia pestis and understanding their molecular mechan
45 owed differences in virulence genes found in Yersinia pestis and Yersinia pseudotuberculosis compared
46 nt of YopJ-dependent cytotoxicity induced by Yersinia pestis and Yersinia pseudotuberculosis paradoxi
47 ages were infected with a panel of different Yersinia pestis and Yersinia pseudotuberculosis strains
50 flammatory response induced by other lethal (Yersinia pestis) and non-lethal (Legionella pneumophila,
51 a and Salmonella enterica serovar Typhi, and Yersinia pestis), and 3 protozoa (Leishmania spp., Plasm
52 athogenicity island, originally described in Yersinia pestis, and encodes proteins with apparent homo
53 Pseudomonas aeruginosa, Salmonella enterica, Yersinia pestis, and Enterococcus faecalis, indicating t
56 des genes from pathogens such as Salmonella, Yersinia pestis, and the virulent Francisella tularensis
58 ut a potential use of the causative bacteria Yersinia pestis as an agent of biological warfare have h
59 gens, including the plague causing bacterium Yersinia pestis, avoid activating this pathway to enhanc
60 ion of either Yersinia pseudotuberculosis or Yersinia pestis bacteria express the small RNAs YSR35 or
61 molecule cyclic diguanylate is essential for Yersinia pestis biofilm formation that is important for
63 and type of medium peptides associated with Yersinia pestis biomass and improve the quality of prote
64 a) in a 19th century intestinal specimen and Yersinia pestis ("Black Death" plague) in a medieval too
65 Several gram-negative pathogens, including Yersinia pestis, Burkholderia cepacia, and Acinetobacter
66 ity pathogens, including Bacillus anthracis, Yersinia pestis, Burkholderia mallei, Francisella tulare
68 for the type III secretion system (T3SS) in Yersinia pestis by interaction with the negative regulat
69 nto a constitutively active IpaH enzyme from Yersinia pestis by introduction of single site substitut
70 trument's response to Bacillus anthracis and Yersinia pestis by spiking the liquid sample stream with
71 es the invasiveness of the plague bacterium, Yersinia pestis, by activating plasminogen to plasmin to
75 ine against plague currently consists of the Yersinia pestis capsular antigen F1 and the type 3 secre
89 tructures of three active-site complexes for Yersinia pestis class IV AC (AC-IV)-two with substrate a
90 aled dose of 1.02 x 10(6) CFU of aerosolized Yersinia pestis CO92 (50% lethal dose, 6.8 x 10(4) CFU).
92 Braun lipoprotein (Lpp) and MsbB attenuated Yersinia pestis CO92 in mouse and rat models of bubonic
93 sal instillation of a fully virulent strain, Yersinia pestis CO92, guinea pigs developed lethal lung
98 ella enterica serovar Typhimurium) and HmsT (Yersinia pestis) contain GGDEF domains and are required
101 l infection of BALB/c mice with nonpigmented Yersinia pestis does not result in pneumonic plague.
102 ts the most severe form of disease caused by Yersinia pestis due to its ease of transmission, rapid p
103 ylase (KdoO) from Burkholderia ambifaria and Yersinia pestis, encoded by the bamb_0774 (BakdoO) and t
104 iosynthesis from Mycobacterium tuberculosis, Yersinia pestis, Escherichia coli, Vibrio cholerae, Baci
106 In American grasslands, plague, caused by Yersinia pestis, exemplifies this quiescent-outbreak pat
107 0 degrees C), the causative agent of plague, Yersinia pestis, expresses a profile of genes distinct f
108 of mice with a recombinant fusion protein of Yersinia pestis F1 and LcrV Ags (F1-V) together with EdT
109 plant-made plague vaccine, we expressed the Yersinia pestis F1-V antigen fusion protein in tomato.
110 vaccine, we expressed our model antigen, the Yersinia pestis F1-V antigen fusion protein, with and wi
111 pture-based immunochromatographic dipsticks, Yersinia Pestis (F1) Smart II and Plague BioThreat Alert
112 ewanella oneidensis, Salmonella typhimurium, Yersinia pestis) for training and validation within and
113 s, Bacteroides fragilis, Bacillus anthracis, Yersinia pestis, Francisella tularensis, and Brucella ab
114 aromyces cerevisiae, Pseudomonas aeruginosa, Yersinia pestis, Francisella tularensis, Bacillus anthra
115 uences were designed for Bacillus anthracis, Yersinia pestis, Francisella tularensis, Brucella melite
116 acids from BT organisms (Bacillus anthracis, Yersinia pestis, Francisella tularensis, Brucella spp.,
117 -six distinct strains of Bacillus anthracis, Yersinia pestis, Francisella tularensis, Burkholderia ma
119 entional autotransporters are present in the Yersinia pestis genome, but only one, YapE, is conserved
122 ated human pathogens Salmonella enterica and Yersinia pestis has entailed functional changes in the P
126 utic strategies that prevent infections with Yersinia pestis have been sought for over a century.
127 o conditionally virulent Deltapgm strains of Yersinia pestis; however, fully virulent Y. pestis is no
128 ere, we report the oldest direct evidence of Yersinia pestis identified by ancient DNA in human teeth
129 tudies (influenza A in lesser snow geese and Yersinia pestis in coyotes), we argue that with careful
130 ery that regulates the entry and survival of Yersinia pestis in host macrophages is poorly understood
133 ated with iron(III)-yersiniabactin import in Yersinia pestis In this study, we compared the impact of
136 ns cause host cell death upon infection, and Yersinia pestis, infamous for its role in large pandemic
137 HMBPP/IL-2 administration after inhalational Yersinia pestis infection induced marked expansion of Vg
140 n lymph nodes (LNs), or buboes, characterize Yersinia pestis infection, yet how they form and functio
147 The V antigen (LcrV) of the plague bacterium Yersinia pestis is a potent protective antigen that is u
166 ds that the causative agent of this disease, Yersinia pestis, is able to survive and multiply in both
167 lague, caused by the Gram-negative bacterium Yersinia pestis, is favored by a robust early innate imm
171 tion of putative transmembrane proteins from Yersinia pestis KIM D27 with the combined PF2D and gel e
172 s from cultures of two attenuated strains of Yersinia pestis [KIM D27 (pgm-) and KIM D1 (lcr-)] grown
173 genomic DNA near IL-10 confers resistance to Yersinia pestis KIM5 and contributes to the observed res
175 ive TnphoA mutant library was constructed in Yersinia pestis KIM6 to identify surface proteins involv
176 ing the human pathogens Burkholderia mallei, Yersinia pestis, Klebsiella pneumoniae, Legionella longb
177 Since possible exposure to plague is via Yersinia pestis-laden aerosols that results in pneumonic
179 ia enterocolitica yscM1 and yscM2 as well as Yersinia pestis lcrQ, relieve the YopE-DHFR-imposed bloc
180 d monoclonal antibodies with specificity for Yersinia pestis LcrV and F1 antigens protected mice in a
186 cessfully produce disease, the causal agent (Yersinia pestis) must rapidly sense and respond to rapid
187 biothreat agents such as Bacillus anthracis, Yersinia pestis, or Burkholderia pseudomallei Convention
189 high mortality, but the mechanisms by which Yersinia pestis overwhelms the lungs are largely unknown
191 total of ca. 36 kb of DNA from the ca. 70-kb Yersinia pestis pCD1 virulence plasmid were constructed
194 lly attenuated, pigmentation (Pgm)-deficient Yersinia pestis primes T cells that protect mice against
195 rate chain to the 2' position of lipid A, in Yersinia pestis produced bisphosphoryl hexa-acylated lip
198 ymerization of a single protein, e.g., YscF (Yersinia pestis), PscF (Pseudomonas aeruginosa), PrgI (S
199 n model of pneumonic plague, it appears that Yersinia pestis quickly creates a localized, dominant an
200 Pneumonic plague, caused by inhalation of Yersinia pestis, represents a major bioterrorism threat
205 hat the base pairing function of E. coli and Yersinia pestis SgrS homologs is critical for rescue fro
210 to approximately 100 50% effective doses of Yersinia pestis strain CO92 and necropsied at 24-h inter
212 lague, we have sequenced the genomes of four Yersinia pestis strains isolated from the zoonotic roden
214 malian body temperature, the plague bacillus Yersinia pestis synthesizes lipopolysaccharide (LPS)-lip
215 roinflammatory responses through TLRs by the Yersinia pestis T3S needle protein, YscF, the Salmonella
217 f the enzootic maintenance of the bacterium (Yersinia pestis) that causes plague and the sporadic epi
220 nse is a prominent feature of infection with Yersinia pestis, the agent of bubonic and pneumonic plag
222 r gene products are functional receptors for Yersinia pestis, the agent of plague, as shown by overex
225 The arthropod-borne transmission route of Yersinia pestis, the bacterial agent of plague, is a rec
228 ly, there is no FDA-approved vaccine against Yersinia pestis, the causative agent of bubonic and pneu
235 hat distinguish DNA amplicons generated from Yersinia pestis, the causative agent of plague, from the
264 in the delivery of cytotoxic Yop proteins by Yersinia pestis, the mechanism has not been defined.
266 festation of disease caused by the bacterium Yersinia pestis, there is surprisingly little informatio
268 edium- to high-copy-number plasmid clones of Yersinia pestis topoisomerase I (YpTOP) with Asp-to-Asn
269 hionine residue with arginine in recombinant Yersinia pestis topoisomerase I (YTOP) was the only subs
272 mal system for interrogating such couplings: Yersinia pestis transmission exerts intense selective pr
275 n, the serine/threonine kinase YopO (YpkA in Yersinia pestis), uses monomeric actin as bait to recrui
276 ulation tests for Francisella tularensis and Yersinia pestis, using a well-established hybridization
279 the possible role of Na(+)/H(+) antiport in Yersinia pestis virulence and found that Y. pestis strai
280 To validate these vector attributes, the Yersinia pestis virulence antigen LcrV was used to devel
281 es that demonstrated a role played by Lpp in Yersinia pestis virulence in mouse models of bubonic and
282 ro, His-tagged recombinant LcrV (rLcrV) from Yersinia pestis was cloned and expressed in Escherichia
283 for antimicrobial susceptibility testing of Yersinia pestis was evaluated in comparison with broth m
284 tion of the highly virulent plague bacterium Yersinia pestis was the acquisition of plasmid pPCP1, wh
285 end, immunity to LcrV, a protective Ag from Yersinia pestis, was tested in young and old baboons.
286 and genome evolution of the plague bacterium Yersinia pestis, we have sequenced the deep-rooted strai
287 atory mice are usually highly susceptible to Yersinia pestis, we recently identified a mouse strain (
288 .3, raised to the LcrV virulence factor from Yersinia pestis were characterised for their Fab affinit
289 that includes serious pathogens such as the Yersinia pestis, which causes plague, Yersinia pseudotub
290 the involvement of RovA in the virulence of Yersinia pestis, which naturally lacks a functional inv
292 ent resistance) in the pathogenic Yersiniae (Yersinia pestis, Y. enterocolitica, and Y. pseudotubercu
294 of Vibrio cholerae vibriobactin and HMWP2 of Yersinia pestis yersiniabactin assembly lines were evolv
295 two inorganic iron ABC transport systems of Yersinia pestis, Yfe and Yfu, have been characterized.
297 eins, the Shigella flexneri OspF protein and Yersinia pestis YopH protein, to rewire kinase-mediated
299 e of the class IV adenylyl cyclase (AC) from Yersinia pestis (Yp) is reported at 1.9 A resolution.
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