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1 Z score models involved indexed parameters (X/BSA(alpha)
2 Z tests were used to compare cancers on DM versus DBT ex
3 Z-DNA-binding protein 1 (ZBP1), initially reported as an
4 Z-rings were diffuse in cells lacking zapA or zauP and,
5 Z-scan measurements revealed a high third-order nonlinea
6 Z: Little is known about the influence of multiple conse
7 Z[Cu(II)OH] complexes, although shown to be inactive, ar
8 substrate scope is demonstrated (up to 99:1 Z:E) together with evidence of mechanistic dichotomy via
10 cyclic alkenes in 40-70% yield and 96:4-98:2 Z:E selectivity; here too, reactions were more efficient
11 mall-molecule electron acceptor, 2,2'-((2Z,2'Z)-((6,6'-(5,5,10,10-tetrakis(2-ethylhexyl)-5,10-dihydro
12 e produced 16 SCO-active [Fe(II)(bpp(X,Y))2](Z)2 complexes (Z = BF4 or in one case PF6) in (CD3)2CO s
14 alysed photoisomerisation showed that the (5'Z)-isomer gazaniaxanthin is the main (Z)-isomer of rubix
16 accessible valine-derived aminophenol and a Z- or an E-gamma-substituted boronic acid pinacol ester.
18 tive cyclizations of substrates containing a Z-allylic phosphate tethered to an alkyne are described.
20 Previous results suggested that ZipA is a Z-ring stabilizer, since in vitro experiments it is show
21 s catalyzed by trace copper salts and that a Z- to E-hydrazone isomerization occurs through an enehyd
22 nduces a sequential reaction path in which a Z-E photoisomerization of C2-C3 is followed by a rotatio
23 termediates show an innate preference for a (Z)-configuration, although this can be suppressed by ste
25 suggest a model where multiple alpha-actinin/Z-repeat interactions cooperate to ensure long-term stab
26 ular version of this approach also afforded (Z)-alpha,beta-unsaturated amino esters in moderate to go
28 -1.36, 95% CI -1.44 to -1.27, weight-for-age Z score -1.20, -1.28 to -1.11, and head circumference Z
29 ritional status at 24 months (length-for-age Z score -1.36, 95% CI -1.44 to -1.27, weight-for-age Z s
31 s), and seven had implausible length-for-age Z scores (<-5 SD; one in intervention cluster; six in co
36 here too, reactions were more efficient and Z-selective than when the other catalyst classes are emp
37 s enantioseparation of E(R), Z(R), E(S), and Z(S) isomers, with a characteristic interconversion zone
39 tly related to the reference temperature and Z-value commonly used for kinetic analysis in food micro
40 adapter-inducing interferon-beta (TRIF) and Z-DNA-binding protein 1 (ZBP1)/DNA-dependent activator o
41 ly imperils the persistence of L. tumana and Z. glacier throughout their ranges, highlighting the rol
43 tive index difference between the axis X and Z gradually decreased with decreasing temperature, which
44 360 degrees along all three axes (X, Y, and Z), by employing the geometric property of a 3D structur
47 eaves [(Z)-3-hexenal, (Z)-3-hexen-1-ol, and (Z)-3-hexenyl acetate] were drastically reduced by blanch
49 ary artery luminal dimensions, normalized as Z scores, and is calibrated to both past and current inv
51 baceous and green aromas were identified as (Z)-1,5-octadien-3-one and 3-isobutyl-2-methoxypyrazine.
52 ng, the desmin cytoskeleton and the attached Z-band-bound thin filaments are degraded after ubiquitin
53 By incorporation of commercially available Z-butene together with robust and readily accessible Ru-
54 retention of oscillatory behavior for the B-Z reaction with the formation of giant vesicles bring a
55 d movement of FtsZ clusters around bacterial Z-rings that is powered by GTP hydrolysis and guides cor
60 including adhesion plaques and dense bodies (Z-disks) of striated muscles and attachment plaques of s
63 ty in the hydrogenation of E/Z mixtures (ca. Z/E = 75:25) of alpha,beta-dialkylvinyl substrates, whil
64 docrine-refractory metastatic breast cancer, Z-endoxifen provides substantial drug exposure unaffecte
68 CO-active [Fe(II)(bpp(X,Y))2](Z)2 complexes (Z = BF4 or in one case PF6) in (CD3)2CO solution: again
69 ge from baseline to 36 months on a composite Z score combining four cognitive tests (free and total r
72 axanes in up to 85% yield; the corresponding Z-hydrazone thread affords no rotaxane under similar con
75 assemble at midcell to form the cytokinetic Z-ring, which coordinates peptidoglycan (PG) remodeling
78 This multicenter study sought to determine Z scores for common measurements adjusted for body surfa
81 ggering the reverse isomerization direction (Z --> E) by the same wavelength of light, which normally
82 aline-like bodies adjacent to a disorganized Z-line on electron microscopy, recapitulating the diseas
88 d ultrarobust antifouling zwitterionic (DURA-Z) coating is created that can be easily and universally
89 aled, among others, over-expression of ESC/E(Z) complex genes (an ovarian steroid-regulated gene sile
90 Finally, mRNA expression of several ESC/E(Z) complex genes were increased by progesterone in contr
92 In contrast, protein expression of ESC/E(Z) genes was decreased in untreated PMDD LCLs with MTF2,
93 These natural products have in common an E,Z-configured conjugated diene linked to a di- or triyne
94 lection of components of a diastereomeric (E,Z) and enantiomeric (R,S) oxime into a third reactor col
95 plant volatile compound pear ester ethyl-(E,Z)-2,4-decadienoate, while CpomOR6a responds to the stro
96 method to stereoselectively establish the E,Z-diene part, an ester-tethered ring-closing metathesis/
97 approach based on abs conversion type (i.e. Z = |X 1 - X 2|) and t-test, to detect interactions in s
98 ti/syn) and E-linear products (up to >20:1 E/Z) in high selectivity with aromatic, alpha,beta-unsatur
100 t the enantioselective, regioselective and E/Z-selective allylic oxidation of unactivated internal al
103 ess to generate enals from ynals with good E/Z selectivity, our early studies found that an asymmetri
104 enantioselectivity in the hydrogenation of E/Z mixtures (ca. Z/E = 75:25) of alpha,beta-dialkylvinyl
109 t formation of photoisomers from CBDs with E/Z configuration must be taken into account because of th
110 y responses in participants in the ChAd3-EBO-Z group (63.5%) and in those in the rVSVG-ZEBOV-GP group
111 s (in 28.5% of the patients in the ChAd3-EBO-Z group and 30.9% of those in the rVSVG-ZEBOV-GP group,
112 n in 40 participants (8.0%) in the ChAd3-EBO-Z group, in 47 (9.4%) in the rVSVG-ZEBOV-GP group, and i
113 e chimpanzee adenovirus 3 vaccine (ChAd3-EBO-Z) and the recombinant vesicular stomatitis virus vaccin
116 20) in aqueous extracts and heavy elements (Z > 20) in acid extracts, coming from materials and degr
117 on was developed to quantify light elements (Z </= 20) in aqueous extracts and heavy elements (Z > 20
118 have formed in low-metallicity environments (Z=0.001) from progenitor binaries with typical total mas
122 d hydrogels directly from conventional AFM F-Z experiments, thereby creating a common platform for th
123 -ZapB provide additional positional cues for Z-ring formation and may help coordinate its assembly wi
124 decrease in kH has been instead measured for Z = OAc, NPhth, CO2Me, Cl, Br, and CN, indicative of alp
126 H2 activation toward CumO(*) is observed for Z = Ph, OH, NH2, and NHAc, as evidenced by an increase i
128 es resulted in hydroboration, 84-86% ee for (Z)-alkenes, but (E)-alkenes or 1,1-disubstituted alkenes
129 Z, and the stabilization of the newly formed Z-rings is crucial for completion of septum synthesis.
130 desuccinylase (DapE) facilitates functional Z ring formation by strengthening the Ter signal via Zap
131 eoretentive catalysts that not only generate Z-olefins selectively, but also kinetically produce E-ol
135 rmal ring openings of the cyclobutenes give (Z,Z)-1,3-diene products, again for thermodynamic reasons
136 gy to include a bioinspired, catalytic E --> Z isomerization of alpha,beta-unsaturated nitriles, ther
137 Combined with light-controlled E --> Z isomerization, this enables controllable fractional tu
145 is impaired in H2A.Z deposition, and by H2A.Z profiling in stress conditions, we investigated the im
149 re-mRNA splicing and indicate a role for H2A.Z in coordinating the kinetics of transcription elongati
151 tably, affected introns are enriched for H2A.Z occupancy and more likely to contain nonconsensus spli
152 g of SWR to both H2A nucleosome and free H2A.Z induces SWR ATPase activity and engages the histone ex
153 ed protein6 mutant, which is impaired in H2A.Z deposition, and by H2A.Z profiling in stress condition
156 intron-containing genes in cells lacking H2A.Z is impaired, particularly under suboptimal splicing co
157 Two internal protein regions mediate H2A.Z-specificity and nucleosome interaction, whereas the PW
161 propose that the antagonistic effects of H2A.Z and HSF1 provide a mechanism to activate gene expressi
162 termine the comprehensive interactome of H2A.Z and identify PWWP2A as a novel H2A.Z-nucleosome binder
163 t in drought-responsive genes, levels of H2A.Z in the gene body correlate with transcript levels.
164 H2A.Z occupancy, the C-terminal tail of H2A.Z is one important mediator to recruit PWWP2A to chromat
166 ects, indicating that, in the absence of H2A.Z, stalled spliceosomes are disassembled, and unspliced
167 ucleosomes and the selective exchange of H2A.Z-H2B dimers out of nucleosomes and replacement by H2A-H
169 n of disassembly factor Prp43 suppresses H2A.Z-mediated splice defects, indicating that, in the absen
171 Together, these data demonstrate that H2A.Z is required for efficient pre-mRNA splicing and indica
173 Together, our findings reveal unique H2A.Z surface dependences for Nap1 and Chz1 and a redundant
176 column for E right harpoon over left harpoon Z isomerization under controlled oven temperature and fl
177 acid-binding domains for left-handed helix (Z-form) and receptor-interacting protein homotypic inter
178 n volatiles in fresh leaves [(Z)-3-hexenal, (Z)-3-hexen-1-ol, and (Z)-3-hexenyl acetate] were drastic
184 his class of reactions four pathways (Type I Z, Type I E, Type II Z, Type II E) are possible, leading
187 s four pathways (Type I Z, Type I E, Type II Z, Type II E) are possible, leading to different enantio
190 e strong support for a CO2 response of gm in Z. mays, and indicate that gm in maize is probably drive
193 that mutation of key amino acids involved in Z-DNA/RNA binding in ZBP1's ZBDs prevented necroptosis u
196 uses the premature disassembly of individual Z-rings, leading to the frequent abortion of septum synt
197 f mesenchymal cells with the Cat L inhibitor Z-FY-CHO led to nuclear-to-cytoplasmic relocalization of
200 ltivariate analysis, patients with irregular Z line and patients with BE of >/= 1 cm did not differ s
202 study, we found that patients with irregular Z line do not develop HGD or esophageal cancer within 5
209 the (5'Z)-isomer gazaniaxanthin is the main (Z)-isomer of rubixanthin and the (13Z)-isomer is the mai
213 iny (NMR-invisible) population of monomeric (Z)-1 that was formed in a mobile equilibrium from the in
214 propyl ketone added rapidly to the monomers (Z)-1&3THF and (E)-1&3THF with a rate ratio of at least 1
215 for both zebrin positive (Z+) and negative (Z-) cells, though the amplitudes of the phases were larg
216 f cyclobutene, electrocyclic ring-closing of Z-hexatriene, the [1,5]-H shift in Z-pentadiene, and the
218 role in controlling the activation energy of Z-E isomerization as well as the shape of the DSC exothe
221 iferated (3 log increase) in the presence of Z. rouxii, while Z. rouxii growth was suppressed by 4 lo
224 -, regio-, and stereoselective synthesis of (Z) and (E) styryl pyrazoles and benzpyrazoles by the add
226 I) cation [Au(PPh3)](+), a large variety of (Z)-beta-iodoenol esters (39 examples) could be synthesiz
227 inery and that they mediate their effects on Z-ring stability during developmentally controlled cell
228 stereoselective synthesis of either the E or Z alkene from a single isomer of a vinyl coupling partne
229 ne shift affords stereospecifically the E or Z isomer of the 5-alkenyl-4-iminohydantoin products from
231 depending on the imine configuration (E- or Z-imine) and on the nucleophilic attack site (top or bot
232 oducts from the corresponding starting E- or Z-N'-alkenyl urea, each of which may be formed from the
233 partner provides access to either the E- or Z-olefin with excellent yield and stereochemical fidelit
235 Methods We performed a phase I study of oral Z-endoxifen to determine its toxicities, maximum tolerat
237 and its wild relatives Z. mays parviglumis, Z. mays mexicana, and particularly Z. mays huehuetenange
238 e decades ago, the small hydrophobic peptide Z-d-Phe-l-Phe-Gly (FIP) was shown to block MeV infection
239 ion of SS activity for both zebrin positive (Z+) and negative (Z-) cells, though the amplitudes of th
240 (1)Denant) yields enantioseparation of E(R), Z(R), E(S), and Z(S) isomers, with a characteristic inte
241 ing C-C bond formation step leading to the R-Z and S-Z product respectively with TMSQ and MeQd cataly
242 centromeres in maize and its wild relatives Z. mays parviglumis, Z. mays mexicana, and particularly
243 Sonogashira coupling of representative (Z)-beta-iodoenol esters with terminal alkynes, alkynols,
245 bond formation step leading to the R-Z and S-Z product respectively with TMSQ and MeQd catalysts is p
248 L was classified into Band-shaped, Y-shaped, Z-shaped, Trident-shaped, and Complex-shaped configurati
249 one added less rapidly to the less shielded (Z)-1 [but never to (E)-1]; this singly diastereoconverge
250 mice with a nonsense mutation in Mypn showed Z-streaming and nemaline-like bodies adjacent to a disor
251 ion half-lives adopt a T-shaped ground state Z isomer conformation and proceed through a T-shaped iso
252 lective synthesis of fluoroalkyl-substituted Z-homoallylic tertiary alcohols has been developed.
253 ows; 5-sulfo-(E)-caftaric acid (a), 2-sulfo-(Z)-caftaric acid (b), 2-sulfo-(E)-caftaric acid (c), (E)
254 on protein, E3, which contains an N-terminal Z-nucleic acid binding (Zalpha) domain that is critical
256 the E-isomers (4-6) or predominantly as the Z-isomer (3) which in solution is converted to the E-iso
259 med in livers of patients homozygous for the Z allele, with severe liver disease requiring hepatic tr
264 divisome that promotes the integrity of the Z ring by acting through ZapB and raises the possibility
265 ciated with the Z-disc, with over 74% of the Z-disc proteins experiencing robust changes in phosphory
266 me system, expression output of genes on the Z Chromosome is expected to be male-biased, since there
267 preference for dosage-sensitive genes on the Z Chromosome, based on computational and experimental da
268 ace, and ethnicity have small effects on the Z scores that are statistically significant but not clin
269 division proteins are thought to require the Z-ring for recruitment to the future division site.
270 lectronic effect that largely suppresses the Z --> E photoisomerization (the tau torsion) reaction, w
271 c disorders and the liver disease due to the Z mutant of AAT (ATZ) is a prototype of conformational d
272 bond are converted by UV irradiation to the Z-isomers having bifurcated O-H...O...H-X hydrogen bond.
275 und on proteins that are associated with the Z-disc, with over 74% of the Z-disc proteins experiencin
279 isomerization kinetics show that the thermal Z --> E interconversion is 4-fold accelerated upon forma
280 l disubstituted alkynes that were reduced to Z-olefins followed by borepin formation either through a
281 ides a more efficient and selective route to Z-macrocycles relative to previously reported systems.
282 reaction mechanism involving a crucial E-to-Z vinyl-Pd isomerization and a carbon-halogen bond-formi
283 e explore the effects of one such transcript-Z+Agrin-known to be a critical organizer of the NMJ.
284 vealed that the phosphorylation state of two Z-disc kinases (striated muscle-specific serine/threonin
287 of FtsZ assemblies in solution that underlie Z-ring assembly, employing time-resolved x-ray scatterin
291 ncrease) in the presence of Z. rouxii, while Z. rouxii growth was suppressed by 4 log in concurrence
292 low-affinity protein binding (affibody with Z protein), elusive enzyme-substrate interaction (ubiqui
295 xternal ED-XRF calibration for elements with Z > 20 in acid extracts was optimized as a faster and cl
296 RF calibration methodology for elements with Z </= 20 was proposed as an alternative to ion chromatog
297 and non-stereoselective transformations with Z-1,2-dichloroethene and 1,2-dibromoethene can be effect
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