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1     Both complexes contain the Tra1 subunit, a highly conserved 3744-residue protein from the Phospho
2 ) in mouse Gp78 isoform 2 that forms part of a highly conserved 41-amino acid region containing 14-3-
3 -amino group of a specific lysine present on a highly conserved acceptor protein domain, resulting in
4                       Viral protein R (Vpr), a highly conserved accessory protein in primate lentivir
5            Ten patients had mutations within a highly conserved acidic loop of the PPP2R5D-encoded B5
6 sphate isomerase (TIM) barrel structure with a highly conserved active site.
7                       Fear, which represents a highly conserved adaptive response to threatening envi
8                                 By modifying a highly conserved adenosine A2503 in 23S rRNA, methylat
9 cluding two papain-like proteases (PLPs) and a highly conserved ADP-ribose-1''-phosphatase (ADRP) mac
10                                      HTT has a highly conserved Akt phosphorylation site at serine 42
11                                Expression of a highly conserved, alkaline-regulated, sodium ATPase wa
12 from an artemisinin ABPP equivalent confirms a highly conserved alkylation profile, with both endoper
13                The missense mutation affects a highly conserved amino acid and is predicted to severe
14  a damaging mutation, c.567 G > A, affecting a highly conserved amino acid residue (p.Gly189Arg) of t
15              The identified mutation affects a highly conserved amino acid residue in the zinc finger
16 d with the disease in the pedigree, affected a highly conserved amino acid residue, and was predicted
17            We identified 66Y (N1 numbering), a highly conserved amino acid that was critical for the
18                  This missense change alters a highly conserved amino acid within CEP120 (p.Ala199Pro
19                                  We identify a highly conserved amino acid, Gly449, that is necessary
20 phaCPs and hnRNP E proteins), are encoded by a highly conserved and broadly expressed gene family.
21                                     Sleep is a highly conserved and essential behaviour in many speci
22          TAR DNA-binding protein (TDP-43) is a highly conserved and essential DNA- and RNA-binding pr
23                           Arginine finger is a highly conserved and essential residue in many GTPase
24   Epithelial-mesenchymal transition (EMT) is a highly conserved and fundamental process in developmen
25                                       CK2 is a highly conserved and pleiotropic serine/threonine kina
26      alpha-N-terminal methylation represents a highly conserved and prevalent post-translational modi
27         Nonsense-mediated RNA decay (NMD) is a highly conserved and selective RNA degradation pathway
28 nt of the Trm8/Trm82 holoenzyme that effects a highly conserved and specific (m(7)G46) methylation of
29                            The cell cycle is a highly conserved and tightly regulated biological syst
30              NETs are believed to constitute a highly conserved antimicrobial strategy comprising dec
31 PAT family reveals PfDHHC1 to be a member of a highly conserved, apicomplexan-specific clade of PATs.
32                                We found that a highly conserved asparagine (N220) in the first transm
33 binding site had been ablated by deletion of a highly conserved aspartic acid at position 385, which,
34 pproaches identified Asp93, which is part of a highly conserved AspGlu dyad found in all dual domain
35                    The HK component contains a highly conserved ATP-binding site that is considered t
36                           Epibatidine shares a highly conserved binding site with acetylcholine, maki
37              Sphingolipid synthesis involves a highly conserved biosynthetic pathway that produces fu
38 irth (neurogenesis) within the hypothalamus, a highly conserved brain region involved in hyperactivit
39  are present only in angiosperms and possess a highly conserved C-terminal region containing linear m
40                                  We identify a highly conserved C-terminal TBP-interaction domain (CT
41 the alphaB and betaB structural elements and a highly conserved carboxylate-binding loop.
42 rylating targeted protein substrates through a highly conserved catalytic core.
43 g combined with mutational analysis revealed a highly conserved catalytic dyad as well as conserved s
44 he 17b human monoclonal antibody recognizing a highly conserved CD4-induced epitope on gp120 involved
45 acterial phage shock protein (Psp) system is a highly conserved cell envelope stress response require
46 t a post-attachment step by interacting with a highly conserved central alpha helix-rich domain.
47 d panneuronal responses to visual stimuli in a highly conserved central brain region in the fruit fly
48 chromatin structure for quiescence driven by a highly conserved chromatin regulator.
49                                       DEK is a highly conserved chromatin-bound protein whose upregul
50                                 Sirtuins are a highly conserved class of NAD(+)-dependent lysine deac
51 ng zoysiagrass, rice and sorghum genomes and a highly conserved collinearity in the gene order was ob
52  of commensal fungi are mediated by mannans, a highly conserved component of fungal cell walls, since
53 re, we provide evidence for the existence of a highly conserved, continuous, PC-specific epitope sequ
54             Hence, this study has identified a highly conserved, critical peptide in DV that is a tar
55 stal structure of the decaheme MtrC revealed a highly conserved CX8C disulfide that, when substituted
56 ovel missense mutation Cys694Arg that alters a highly conserved cysteine in the RING domain.
57 tantly, ROS also inactivate Sb9 by oxidizing a highly conserved cysteine pair (P1-P1' in rodents and
58        The p.Cys1691Ser substitution affects a highly conserved cysteine residue and is predicted by
59 tion interface by a disulfide bond formed by a highly conserved cysteine.
60                               Pacman/XRN1 is a highly conserved cytoplasmic exoribonuclease which deg
61    Growth arrest specific gene two (GAS2) is a highly conserved cytoskeleton-associated protein whose
62  An allosteric sodium ion was found bound to a highly conserved D2.50 residue in inactive GPCRs, wher
63                                 Autophagy is a highly conserved degradation process that is involved
64 oss-of-function mutations in USP9X, encoding a highly conserved deubiquitinating enzyme.
65 tes directly to autoinhibition by precluding a highly conserved dipole-enhanced hydrogen bond between
66                           We have identified a highly conserved DNA methyltransferase, which we term
67                                     FANCM is a highly conserved DNA remodeling enzyme that promotes t
68                                              A highly conserved DNA uptake system allows many bacteri
69                       The TEC proteins share a highly conserved domain (DUF4123) and are genetically
70                                   They share a highly conserved domain (DUF583) of which the structur
71 dent methylmalonyl-CoA mutase (MCM), HCM has a highly conserved domain architecture.
72 sual case in which an equivalent mutation in a highly conserved domain of yeast and mammalian Erks ca
73 ork mapped the immunosuppressive activity to a highly conserved domain, termed the immunosuppressive
74                              MDA-9/Syntenin, a highly conserved double-PDZ domain-containing scaffold
75                    Lissencephaly-1 (LIS1) is a highly conserved dynein-regulatory factor that binds d
76                         We further show that a highly conserved eight-base-pair segment of SL3 is not
77    Poly (ADP-ribose) polymerase-1 (PARP1) is a highly conserved enzyme focused on the self-repair of
78  (sulfide quinone oxidoreductase) protein is a highly conserved enzyme involved in H2S metabolism.
79 Pterin-4a-carbinolamine dehydratase (PCD) is a highly conserved enzyme that evolved a second, unrelat
80                                        Also, a highly conserved epitope (YGD/XTL) of E6 was found to
81 ds through a coordinated movement of CDRs to a highly conserved epitope encompassing a hydrophobic gr
82 g and transgenic approaches demonstrate that a highly conserved ERG-bound enhancer located upstream o
83                   The bacterial cell wall is a highly conserved essential component of most bacterial
84 d from isoforms LRRC8C and LRRC8E to uncover a highly conserved extracellular region preceding the se
85          SLBP (stem-loop binding protein) is a highly conserved factor necessary for the processing,
86  clamp loader clade, RarA protein is part of a highly conserved family of DNA metabolism proteins.
87                                  Septins are a highly conserved family of proteins in eukaryotes that
88                     We and others identified a highly conserved family of sterol transport proteins (
89                   The flat Golgi cisterna is a highly conserved feature of eukaryotic cells, but how
90                                              A highly conserved FLV motif was identified in the C-ter
91 ther, our results demonstrate that IFT88 has a highly conserved function within the primary cilia of
92 022500) that encodes atypical amino acids at a highly conserved functional site.
93 Trace amine-associated receptor 1 (TAAR1) is a highly conserved G-protein-coupled receptor bound by e
94                                  Mutation of a highly conserved 'gating charge' residue in the S4 hel
95                                     KCNQ5 is a highly conserved gene encoding an important channel fo
96 -related oncogene; also known as DCUN1D1) is a highly conserved gene that functions as an E3 in neddy
97                                  Gephyrin is a highly conserved gene that is vital for the organizati
98 dy, two basic amino acids, R128 and R129, in a highly conserved GKYLQRRLQ motif were determined to be
99                       We have now identified a highly conserved glutamate residue in the transmembran
100 bstitutions (p.Glu117Val and p.Glu117Gly) at a highly conserved glutamic acid residue located in the
101 llular form of the prion protein (PrP(C)) is a highly conserved glycoprotein mostly expressed in the
102      We identified murein lipoprotein (MLP), a highly conserved gram-negative outer membrane protein,
103 ant (OR 0.58; 95% CI 0.36-0.94; P = .028) in a highly conserved haplotype region surrounding the LCT
104                         PEP87 corresponds to a highly conserved helical region of the HA2 subunit of
105                     The mutant protein lacks a highly conserved helix consisting of the C-terminal fo
106  the conformation of the heme and changes in a highly conserved helix I motif that is associated with
107 yzed to date, serine palmitoyltransferase is a highly conserved heterodimeric enzyme complex.
108 l domain are facilitated by the Bam complex, a highly conserved heteroligomer that plays a general ro
109  or the periplasm of bacteria is mediated by a highly conserved heterotrimeric membrane protein compl
110               Replication protein A (RPA) is a highly conserved heterotrimeric single-stranded DNA-bi
111  cytochrome b561), and abolished by mutating a highly conserved His residue (H292L) predicted to coor
112 al, and mass spectrometry analyses show that a highly conserved His, immediately N-terminal to His(nu
113 enesis and biophysical studies revealed that a highly conserved histidine (His(113)) functions as a p
114 nally, all types of neurons are specified in a highly conserved histogenic order, although its signif
115                       Nucleoplasmin (Npm) is a highly conserved histone chaperone responsible for the
116                              Histone H3.3 is a highly conserved histone H3 replacement variant in met
117                                     H2A.Z is a highly conserved histone variant involved in several k
118                                     H2A.Z is a highly conserved histone variant of the canonical hist
119 esidues adjacent to Asn-110 and Asn-137 form a highly conserved hydrophobic cleft interacting with th
120            Our data reveal that splicing has a highly conserved impact on the availability of sodium
121 vel neutralizing monoclonal antibody targets a highly conserved internal fusion loop in the glycoprot
122                     The Lon AAA+ protease is a highly conserved intracellular protease that is consid
123  the discovery of target of rapamycin (TOR), a highly conserved kinase and central controller of cell
124 may be functionally redundant, as they share a highly conserved kinase domain.
125 s of mechanistic target of rapamycin (mTOR), a highly conserved kinase within a nutrient-sensing path
126      Specifically, three-toed sloths possess a highly conserved, low-diversity foregut community with
127 haploinsufficiency for LOX or are located at a highly conserved LOX catalytic domain, which is relati
128 L4-ROC1 E3 ubiquitin ligase (CRL4(VprBP)) on a highly conserved lysine residue.
129 nonstructural protein 3 (nsP3) that contains a highly conserved MacroD-type macrodomain at the N term
130               Its crystal structure revealed a highly conserved macrodomain fold.
131 on is a core cellular process carried out by a highly conserved macromolecular machine, the ribosome.
132 ne the metabolic responses to dietary AAs in a highly conserved manner.
133                                      AMPK is a highly conserved master regulator of metabolism, which
134       Catabolite control protein A (CcpA) is a highly conserved, master regulator of carbon source ut
135                          Tenascin-C (TNC) is a highly conserved matricellular protein with a distinct
136  factor (SRF)-mediated gene transcription is a highly conserved mechanism that connects dynamic reorg
137 romote epigenetic transcriptional poising by a highly conserved mechanism.
138 ct with and activate Galpha proteins through a highly conserved mechanism.
139                                   UNC-45A is a highly conserved member of the UNC-45/CRO1/She4p famil
140 respectively) envelope glycoproteins contain a highly conserved, membrane-proximal endocytosis motif
141 ults demonstrate the selective inhibition of a highly conserved metabolic enzyme that contains identi
142         swip-10 encodes a protein containing a highly conserved metallo-beta-lactamase domain, within
143 on that encodes a substitution of valine for a highly conserved methionine (p.Met184Val) in both affe
144 we show that a homozygous mutation affecting a highly conserved MFSD2A residue (p.Ser339Leu) is assoc
145  nuclear receptor and major drug target, has a highly conserved minor splice variant, GRgamma, which
146 entameric ligand-gated ion channels, sharing a highly conserved modular 3D structure.
147          In this study, we found that HSP90, a highly conserved molecular chaperone, is overexpressed
148  the R128A or R129A mutation introduced into a highly conserved motif ((123)GKYLQRRLQ(131)) reduced t
149 s physically interact with tankyrase through a highly conserved motif at their N terminus, and mutati
150 tic analysis revealed that the PRR contained a highly conserved motif of 18 amino acids.
151 n inhibits cell wall synthesis by binding to a highly conserved motif of lipid II (precursor of pepti
152           The major homology region (MHR) is a highly conserved motif that is found within the Gag pr
153 Rs) from diverse animal phyla and identified a highly conserved motif, which we termed the "hydrophob
154 ilable structural information, we identified a highly conserved motif.
155 is domain, these four amino acids constitute a highly conserved motif.
156 The target of rapamycin complex 1 (TORC1) is a highly conserved multiprotein complex that functions i
157 d by removal of the GPI-modification signal, a highly conserved N-glycan or the deletion of predicted
158 elated voltage-gated potassium channels have a highly conserved N-linked glycosylation site in the fi
159                  The proteostasis network is a highly conserved network of cellular stress responses
160                      PAR proteins constitute a highly conserved network of scaffolding proteins, adap
161 mediated by the hypothalamic-pituitary axis, a highly conserved neurohormonal cascade that culminates
162 an ortholog of the mammalian neuropeptide Y, a highly conserved neuromodulator that stimulates food-s
163 rates thyrotropin-releasing hormone (TRH) is a highly conserved neuropeptide that exerts the hormonal
164      Interestingly, this regulation required a highly conserved NF-kappaB-binding site but not a pred
165             Heterochromatin protein 1 (HP1), a highly conserved non-histone chromosomal protein in eu
166                                     MHC-E is a highly conserved nonclassical MHC class Ib molecule th
167     The m.7551A > G mutation is localized at a highly conserved nucleotide(A37), adjacent (3') to the
168                        The primary cilium is a highly conserved organelle housing specialized molecul
169              Mammalian Ecdysoneless (ECD) is a highly conserved ortholog of the DrosophilaEcd gene pr
170 eport the identity of swip-13, which encodes a highly conserved ortholog of the human atypical MAP ki
171 tion of the hedgehog (Hh) signaling pathway, a highly conserved pathway best understood for its role
172                Wnt/beta-catenin signaling is a highly conserved pathway essential for embryogenesis a
173          Nucleotide excision repair (NER) is a highly conserved pathway that removes helix-distorting
174                            This uORF encodes a highly conserved peptide (CPuORF) that is present in v
175 acterized by low cell-surface expression and a highly conserved peptide-binding cleft.
176               DNA binding was dependent upon a highly conserved Phe residue (F65) that in human POT1
177 neurotoxicity in HIV-infected macrophages is a highly conserved phenotype of macrophage-tropic HIV st
178 in Drosophila demonstrated the importance of a highly conserved phenylalanine for Pur-alpha's unwindi
179                                Intriguingly, a highly conserved phosphomimetic RxEP motif in NS3 was
180                             Phosducin (Pdc), a highly conserved phosphoprotein involved in the regula
181 ed by cAMP-dependent protein kinase (PKA) at a highly conserved phosphorylation site and by cyclin-de
182 roliferating cell nuclear antigen (PCNA) via a highly conserved PIP box motif within the kinase domai
183 tural and functional domains; in particular, a highly conserved pore-loop sequence that determines th
184 plants is an additional function of NIa-Pro, a highly conserved potyvirus protein.
185                   Each of these proteins has a highly conserved primary activity; however, numerous a
186                             Melanogenesis is a highly conserved process of cytophotoprotection from U
187 b development has otherwise been shown to be a highly conserved process.
188                               COP9, which is a highly conserved protein complex composed of eight CSN
189 cinate dehydrogenase complex (complex II) is a highly conserved protein complex composed of the SDH1
190                                    SMC5/6 is a highly conserved protein complex related to cohesin an
191 s an ABCB1 auxin transporter and Dw1 encodes a highly conserved protein involved in the regulation of
192                                     Rad52 is a highly conserved protein involved in the repair of DNA
193          The vaccinia virus B1R gene encodes a highly conserved protein kinase that is essential for
194 Proliferating cell nuclear antigen (PCNA) is a highly conserved protein necessary for proper componen
195 XPhi uses an infection strategy that targets a highly conserved protein of Gram-negative bacteria ess
196                    Bax inhibitor 1 (BI-1) is a highly conserved protein originally identified as a su
197                                  Scribble is a highly conserved protein regulator of cell polarity th
198                                       NS1 is a highly conserved protein secreted at high concentratio
199                                 TPM1 encodes a highly conserved protein that regulates muscle contrac
200 id of secretome phage display, we identified a highly conserved protein that specifically binds and i
201                TD-60 (also known as RCC2) is a highly conserved protein that structurally resembles t
202                                              A highly conserved protein, ACTA1 is implicated in multi
203                RadA (also known as 'Sms') is a highly conserved protein, found in almost all eubacter
204 nts, indicating that CdiA-CT(EC536) exploits a highly conserved protein-protein interaction to promot
205 pocampus.Finally, we confirm that Lhx2 binds a highly conserved putative enhancer of Dmrt5, suggestin
206  of Haemophilus influenzae LpoA (HiLpoA) has a highly conserved, putative substrate-binding cleft bet
207 lyzed by O-acetylserine sulfydrylase (OASS), a highly conserved pyridoxal 5'-phosphate (PLP)-dependen
208 in organization, and both subclasses contain a highly conserved Rab-binding domain at their C termini
209                                      CRM1 is a highly conserved, RanGTPase-driven exportin that carri
210                                 Autophagy is a highly conserved recycling process that involves degra
211 associated (CA) HIV-1 DNA and RNA, targeting a highly conserved region in HIV-1pol, with sensitivitie
212 ucleotide polymorphisms, one of which was in a highly conserved region of a gene encoding a sensor ki
213 inkage at multiple sites near the D1 domain, a highly conserved region of bacterial flagellins that i
214                           We also discovered a highly conserved region of She3p upstream of its hook
215 sed the recently solved crystal structure of a highly conserved region of the Drosophila orthologue o
216 phorylation of a single tyrosine (p*Y504) in a highly conserved region of the fibronectin type III (F
217                   This variant is in exon 2, a highly conserved region of the gene.
218    A RNA interference construct, designed to a highly conserved region of these genes, was used to tr
219  TLR13 has recently been identified to sense a highly conserved region within bacterial 23S rRNA.
220  gene in human Chanarin-Dorfman syndrome, is a highly conserved regulator of adipose triglyceride lip
221 ome remodeling deacetylase (NuRD) complex is a highly conserved regulator of chromatin structure and
222                                      Gle1 is a highly conserved regulator of RNA-dependent DEAD-box A
223                      The JAK/STAT pathway is a highly conserved regulatory module, activated by many
224                         These pathways share a highly conserved regulatory molecule, beta-catenin, wh
225 ontrolled by the orientation of arginine 66, a highly conserved residue in Anthozoan PCFPs.
226 ed missense mutation c.591C>A p.Glu197Asp in a highly conserved residue in exon 4 of ACTA1.
227 ar, the p.Thr270Ala missense variant affects a highly conserved residue in the DBL homology domain, w
228                                      C479 is a highly conserved residue in the extracellular domain o
229                               Moreover, W69, a highly conserved residue located at the interface betw
230 persistent PKD1 phosphorylation at Ser(203), a highly conserved residue located within the PKD1 N-ter
231                  These results indicate that a highly conserved residue of an ABC transporter plays a
232 dentified a single novel missense variant in a highly conserved residue of FLNC (filamin C; p.V2297M)
233 mouse model with an RNase H2 AGS mutation in a highly conserved residue of the catalytic subunit, Rna
234                  Previous studies identified a highly conserved residue of the inner domain, W69, as
235 causes a missense mutation (p.Arg2024Gln) in a highly conserved residue that is essential for carbamo
236                           The mutation is at a highly conserved residue within the DNA binding domain
237          This study investigates the role of a highly conserved residue, tryptophan residue 420, of t
238 tion responsible encodes the substitution of a highly conserved residue, which lies outside the benza
239 criptomes were broadly similar and exhibited a highly conserved response to LPS.
240 iggering nonsense-mediated mRNA decay (NMD), a highly conserved RNA degradation pathway.
241                                     eIF4A is a highly conserved RNA-stimulated ATPase and helicase in
242 cribe the identification of translin (trsn), a highly conserved RNA/DNA binding protein, as essential
243                 One of these subclades plays a highly conserved role in cell division, while the dist
244 coded protein associates with rRNA and plays a highly conserved role in the maturation of the 60S rib
245 tion in zebrafish cloche mutants, indicating a highly conserved role in vertebrate vasculogenesis and
246 tural accessions of this species, indicating a highly conserved role of this protein in controlling o
247                Instead, our analysis reveals a highly conserved salt-bridge network, which likely has
248           This is achieved in part by Notum, a highly conserved secreted feedback antagonist.
249 o the complex by engaging the latter through a highly conserved segment adjacent to the helical HID s
250                                              A highly conserved self-antigen, nonmuscle myosin heavy
251                                 Autophagy is a highly conserved self-degradative process that has a k
252                                 Autophagy is a highly conserved self-digestion process, which is esse
253 at a single amino acid change (Arg135Gly) in a highly conserved sensor kinase (LiaS) of a poorly defi
254 sp/Glu-rich hypervariable region followed by a highly conserved sequence comprising two potential HXH
255          A cross-species analysis identifies a highly conserved sequence element in LINC-PINT that is
256                                              A highly conserved sequence motif on helix I contributes
257                           Phosphorylation of a highly conserved serine cluster in the intracellular d
258                                              A highly conserved serine located at position 375 in gro
259 ng identified a germline mutation (S631G) at a highly conserved serine residue in the uncharacterized
260                               PP2A(Cdc55) is a highly conserved serine-threonine protein phosphatase
261                                              A highly conserved set of approximately 1,000 proteins i
262                           Granzyme B cleaves a highly conserved set of proteins in all three bacteria
263                 The Hedgehog (Hh) pathway is a highly conserved signaling cascade crucial for cell fa
264 tivates the unfolded protein response (UPR), a highly conserved signaling cascade that functions to a
265 f intragenic suppressors, all located within a highly conserved six amino acid tether region of ISP-1
266 ious GAS M-Prts have shown that they contain a highly conserved sortase A-dependent cell wall-anchore
267                                              A highly conserved Sox2/Pax6 bound site near the Sprouty
268                          Maresin 1 (MaR1) is a highly conserved specialized proresolving mediator (SP
269            Exogenous administration of MaR1, a highly conserved SPM, propagated inflammatory resoluti
270 ractions networks (PPINs) are known to share a highly conserved structure across all organisms.
271                                      This is a highly conserved structure and the target of numerous
272                  Our data show that, despite a highly conserved structure, elements of substrate spec
273 e fine specificity is strongly influenced by a highly conserved substitution that regulates receptor
274                         The RSV F protein is a highly conserved surface glycoprotein and is the main
275 n PHF5A demonstrating that Y36 is located on a highly conserved surface.
276 r the stability of the fold, forming part of a highly conserved symmetrically repeating hydrogen-bond
277                                     Fever is a highly conserved systemic response to infection dating
278      Repressor/activator protein 1 (RAP1) is a highly conserved telomere-interacting protein.
279                                      KstR is a highly conserved TetR family transcriptional repressor
280                                              A highly conserved threonine near the C terminus of gp12
281 AZ-bound transcription factors, and contains a highly conserved TIF[F/Y]XG motif that defines the lar
282  RIZ homology domain containing 8 (PRDM8) as a highly conserved transcription factor that is abundant
283 this resilience is linked to the activity of a highly conserved transcription factor, nuclear factor
284                         Eyes absent (Eya) is a highly conserved transcriptional coactivator and prote
285                                  Mediator is a highly conserved transcriptional coactivator organized
286 function of elongation factor 4 (EF-4/LepA), a highly conserved translational GTPase, has remained el
287 ce lacking the p75(NTR) death domain (DD) or a highly conserved transmembrane (TM) cysteine residue (
288                                RNase Z(L) is a highly conserved tRNA 3'-end processing endoribonuclea
289 h results from cis/trans isomerization about a highly conserved Trp-Pro imide bond in a region of the
290                           Here, we show that a highly conserved tryptophan at position 69 of the gp12
291                   The Hippo (Hpo) pathway is a highly conserved tumor suppressor network that restric
292  we identify Abl-mediated phosphorylation of a highly conserved Tyr residue in the P + 1 loop of prot
293  toggle switch for sensing agonists involves a highly conserved tyrosine residue in helix VI.
294 methyl group of dTMP apparently clashes with a highly conserved tyrosine residue, preventing the form
295                        Rather, we discovered a highly conserved tyrosine-based motif in the third int
296 ajor histocompatibility complex E (MHC-E) is a highly conserved, ubiquitously expressed, nonclassical
297                                     WDR92 is a highly conserved WD-repeat protein that has been propo
298 matin assembled from the IGFBP1 promoter via a highly conserved winged helix motif.
299 cysteine residues to form disulfide bonds at a highly conserved zinc site.
300 y of the Vpx- or Vpr-CRL4 E3 ligase requires a highly conserved zinc-binding motif.

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