ライフサイエンスコーパス: a large excess of

1 lated catalytic domain after incubation with a large excess of 7, 8-dihydropterin, DTT, and Fe(2+).

2 y for the detection of HZ in the presence of a large excess of a common active pharmaceutical ingredi

3 A large excess of a single-base mismatch oligonucleotide

4 of larger DNA components in the presence of a large excess of a smaller DNA component or in a DNA mi

5 dified protein by addition of a phosphine or a large excess of a thiol.

6 A large excess of ALDH3A1 also protected glucose-6-phosp

7 cid for activation and that is stable toward a large excess of ammonia.

8 diphosphate (AMPPNP) promote ADP binding and a large excess of AMPPNP is required to displace ADP fro

9 d reaction conditions, and avoids the use of a large excess of an alcohol nucleophile.

10 In each case, there was a large excess of AT-->GC compared to GC-->AT mutations

11 s-palladacycle catalysts required the use of a large excess of benzoic anhydride (which is very diffi

12 eling protocols that use this enzyme require a large excess of both substrate and sortase to produce

13 selectivity toward Con A in the presence of a large excess of bovine serum albumin (BSA).

14 e proximity to each other in the presence of a large excess of buffer.

15 creased 2.5-2.7 fold after pretreatment with a large excess of C225.

16 is enhancement is reduced by the addition of a large excess of Ca(II), indicating that these ions bin

17 ent number of anionic charges, were added to a large excess of cationic surfactant (dodecyltrimethyla

18 240-fold by a single-pass cell sorting from a large excess of cells expressing WT antibody with a sl

19 In the presence of a large excess of Cl(-) ([I(-)] approximately 10 mM and

20 We detected the BSE prion protein within a large excess of classical, atypical, and CH1641 scrapi

21 , working in the presence of added water and a large excess of CO2 (40 atm), in addition to CuCl2 and

22 MerB/Hg/DTT complex, even in the presence of a large excess of competing cysteine, has been demonstra

23 Na(Hg) reduction in acetonitrile containing a large excess of cryptand[2.2.2] exhibits a Hush-type i

24 gests that catalyst deactivation occurs with a large excess of cyanamide over longer reaction times.

25 Reacting [(Me(3)tacn)Mo(CN)(3)] with a large excess of [(cyclam)Ni(H(2)O)(2)](2+) produces a

26 meric, unspliced viral RNA in the context of a large excess of cytosolic human RNAs.

27 In the absence of CO2, the addition of a large excess of DBU to [(LCu)2H](+) results in an equi

28 onto stromal feeder cells in the presence of a large excess of differentiated OE neurons.

29 When a large excess of divalent metal ions is absent, the cha

30 When a large excess of divalent metal ions is present, the ch

31 Addition of a large excess of DMS to the oxidised enzyme in solution

32 tion of bacteriophage MS2 in the presence of a large excess of E. coli.

33 ation up to 10(-7) M, and of the addition of a large excess of EDTA.

34 pR complex is formed even in the presence of a large excess of EnvZc, OmpR binding to EnvZc is co-ope

35 a is formed by the reaction of an amide with a large excess of ethyl isocyanate at elevated temperatu

36 nversion of creatine to phosphocreatine with a large excess of exogenous ATP, conversion of all ATP t

37 be complemented for pyocyanin production by a large excess of exogenous N-butyryl homoserine lactone

38 extent where it cannot be prevented even by a large excess of external H-atom donor.

39 ies, we show that what is now seen as normal-a large excess of female life expectancy in adulthood-is

40 g Spiroplasma infection continued to produce a large excess of female progeny, while females that had

41 excess of males, among trisomy 18 live borns a large excess of females, and among trisomy 21 live bor

42 fectively than the beta2AR co-expressed with a large excess of G(s alpha).

43 In the presence of a large excess of H2O2, this intermediate rapidly decays

44 h allow HA synthesis even in the presence of a large excess of HA-degrading enzyme.

45 or the observed mutation spectrum, which has a large excess of helical domain mutations.

46 f thiol-stimulated ATPase activity, although a large excess of heme inhibited activity.

47 tified by NMR in the reaction of BH4(-) with a large excess of HN(NO2 )2 .

48 However, in the presence of a large excess of Hsc70, refolding of pmAAT is still arr

49 mor cells were treated with hyaluronidase or a large excess of hyaluronan, indicating that hyaluronan

50 When a large excess of imidazole is added to this five-coordi

51 The assay is carried out in the presence of a large excess of inactive variants of AATase.

52 However, the lysates also contain a large excess of infectious phage particles which compl

53 observed upon treatment of siliconoid 5 with a large excess of iodine in refluxing toluene, thus prov

54 ith these structures even in the presence of a large excess of linear duplex DNA.

55 e cancer (34 cases: SIR 2.41, 1.67-3.36) and a large excess of male breast cancer (five cases: SIR 15

56 ) requires cocrystallization of analyte with a large excess of matrix, which must be mutually soluble

57 in vitro solid MnOx formation when there is a large excess of Mn(II).

58 lar amyloid deposits even in the presence of a large excess of monomeric Abeta or its precursor.

59 for RA, this therapy is not associated with a large excess of mortality nor with an unusual spectrum

60 We find that a large excess of muscle agrin failed to inhibit either

61 Interestingly, coexpression of a large excess of N- or C-terminally deleted P with wild

62 be restored by reacting aqueous OXA-24 with a large excess of NaHCO(3), which recarboxylates Lys84.

63 exceedingly rare sites of damage embedded in a large excess of nearly identical undamaged DNA, while

64 r response is insensitive to the presence of a large excess of non-complementary DNA sequences.

65 d that the identified de novo mutations show a large excess of non-synonymous changes in schizophreni

66 opies of their RNA genomes in the context of a large excess of nongenomic RNA.

67 ulates DNA annealing even in the presence of a large excess of nonhomologous DNA.

68 those found in vivo, and in the presence of a large excess of nonspecific competitor DNA.

69 in, with an effective discrimination against a large excess of nontarget proteins.

70 Under conditions of a large excess of ODI, the reaction is more than 1 order

71 With a large excess of oil, diffusion was also limited, as on

72 em obviates the need for directing groups or a large excess of one of the coupling partners.

73 of reagents, and does not require the use of a large excess of organometallic reagent.

74 Recent analyses have shown that there is a large excess of perfect inverted repeats in many proka

75 ID(50) and PMCAb(50) values could be due to a large excess of PMCAb-reactive prion protein seeds wit

76 As prostatic epithelia produce a large excess of polyamines, the androgen-induced polya

77 se the sortase reaction reaches equilibrium, a large excess of polyglycine nucleophile is often emplo

78 lly identify functional mutations from among a large excess of polymorphisms, incidental mutations, a

79 Despite their importance and a large excess of precursors (i.e., DNA double-strand br

80 on, with extremely low genetic diversity and a large excess of rare polymorphisms.

81 ance proteins of interest in the presence of a large excess of relatively abundant proteins.

82 avored over monomeric interactions even when a large excess of saccharide was present.

83 Finally, we find a large excess of singleton polymorphisms in the full da

84 In particular, materials presenting a large excess of soft elastic modes, the so-called boso

85 species at neutral pH and in the presence of a large excess of spectator ions.

86 There was a large excess of studies replicating the first positive

87 in limited conditions, such as when there is a large excess of substrate over enzyme.

88 The complex can be dismantled by addition of a large excess of tetra-N-butylammonium cations.

89 In antisense transfected cells, a large excess of the antisense transcript was produced

90 e slow, requiring multiple minutes even when a large excess of the challenging protein is present.

91 With a large excess of the deuterated olefin the first exchan

92 nantly monoaryl siloxanes, without requiring a large excess of the electrophile.

93 plasmid DNA were labeled in the presence of a large excess of the helper duplex to compete with the

94 ovalently bound to IgE after incubation with a large excess of the ligand.

95 However, a large excess of the monomeric protein was needed for m

96 how that the formation of the 1T phase under a large excess of the NaBH4 reductant during synthesis c

97 lts Ar(2)CH-PAr(3)(+)X(-) in the presence of a large excess of the nucleophiles.

98 Three relaxation processes are observed at a large excess of the nucleotide, while only two relaxat

99 e next correct dNTP, even in the presence of a large excess of the other dNTPs and rNTPs.

100 species (the enzyme or the substrate) is in a large excess of the other species.

101 poor regioselectivities and the need to use a large excess of the radical-accepting arene have hinde

102 When the Fe(III)(ppq) complex is exposed to a large excess of the sacrificial electron-acceptor ceri

103 A large excess of the selenium precursor, with 5-10 time

104 Addition of a large excess of the soluble mAb subsequent to stimulat

105 a2AR) expressed in Sf9 insect cells requires a large excess of the stimulatory G-protein of adenylyl

106 )A(58) modification, even in the presence of a large excess of total tRNA.

107 UMT which could be reversed by dilution into a large excess of tRNA substrate.

108 ential sorption of Pu(IV) in the presence of a large excess of U(VI).

109 Mixing the cells of a single clone with a large excess of uncloned cells from a subline that was

110 ability to locate 8-oxoguanine lesions among a large excess of undamaged DNA.

111 n in these extracts, even in the presence of a large excess of undamaged DNA.

112 donor ssDNA was monitored after addition of a large excess of unlabeled acceptor ssDNA by using eith

113 led DNA fragments were dissociated by adding a large excess of unlabelled calf thymus DNA.

114 Finding and repairing oxoG in the midst of a large excess of unmodified DNA requires a combination

115 y chromatography using N-His-tagged FliH and a large excess of untagged FliH confirmed that FliH form

116 ed 5-HT(2C) receptors were co-expressed with a large excess of untagged, non-fluorescent 5-HT(2C) rec

117 lex in a 1:1 complex even in the presence of a large excess of VCA.

118 cting a few mutated cells in the presence of a large excess of wild-type cells requires a sensitive a