ライフサイエンスコーパス: a large fraction of

1 h molecular weight (Mw = 928,000 g/mol) with a large fraction of 2 000,000-5,000,000 g/mol molecular

2 rs could hold over 1500 Gt CO2, sequestering a large fraction of 21st century emissions.

3 During this process a large fraction of 6mAs locate in repetitive regions of

4 to understand the consequences of replacing a large fraction of a canonical nucleoside with a modifi

5 ong multiple mutations; and 6) the fact that a large fraction of a protein's amino acids contribute t

6 gion at sufficient frequency to drive CSR in a large fraction of activated B cells.

7 bdenum disulfide that allows the exposure of a large fraction of active edge sites.

8 A large fraction of AEBP2's target loci also map closely

9 Our dipolar-dephased spectra indicated that a large fraction of alkoxy carbons were not protonated.

10 tion that ignore duplicated loci are missing a large fraction of all adaptive substitutions.

11 ing events demonstrated that RBM25 regulates a large fraction of alternatively spliced exons througho

12 A large fraction of amino acid differences between D. ps

13 t role in the global carbon cycle and offset a large fraction of anthropogenic CO2 emissions.

14 SOA comprises a large fraction of atmospheric aerosol mass and can hav

15 A large fraction of atmospheric aerosols are derived fro

16 Ribonucleoproteins represent a large fraction of autoantigens in systemic autoimmune

17 ts with field samples have demonstrated that a large fraction of bioactive trace metals are complexed

18 This is important because a large fraction of brain blood flow is required to main

19 A large fraction of budding coated pits recruit between

20 ll as the TCF3-ID3 and SWI/SNF complexes, in a large fraction of Burkitt lymphomas.

21 environments, which we infer to account for a large fraction of carbon mineralization in this system

22 is a cell-surface molecule over-expressed on a large fraction of carcinomas, and thus is an attractiv

23 abnormality in mitochondrial disorders, but a large fraction of cases remains genetically undetermin

24 udies with thousands of individuals, because a large fraction of causative variant sites can be obser

25 Here we report that a large fraction of cDNA sequences detected in microbial

26 n adults, reporter expression was evident in a large fraction of cells in most tissues of every anima

27 among pioneer TFs, is sufficient to predict a large fraction of cellular chromatin accessibility in

28 ic carbon in atmospheric particles comprises a large fraction of chromatographically unresolved compo

29 howed that the repertoire is polyclonal with a large fraction of clonotype that are only observed onc

30 Diatoms are responsible for a large fraction of CO(2) export to deep seawater, a pro

31 ific serum Ab response in humans consists of a large fraction of cross-reactive, poorly neutralizing

32 als that, independent of cullin neddylation, a large fraction of cullins are assembled with adaptor m

33 ields of major cereal crops are found across a large fraction of current cropland by 2050.

34 protein-coupled receptors (GPCRs) represent a large fraction of current pharmaceutical targets, and

35 A large fraction of cytoplasmic proteins associate with

36 We find that the functions of a large fraction of D. melanogaster enhancers are conser

37 nts showed a diffuse cytoplasm reactivity in a large fraction of DC-LAMP(+) cells, instead of the cla

38 Imaging of intact skin revealed that a large fraction of DDCs, the principal source of IL-23,

39 Most dendrite branches and a large fraction of dendritic spines in the adult rodent

40 nto a soft hydrogel nanocomposite containing a large fraction of dispersed liquid hydrophobic compart

41 -TCRs behave like gammadelta-TCRs and commit a large fraction of DNs toward the gammadelta-lineage, t

42 c surface layer of two rewetted fens removed a large fraction of DOM via coagulation.

43 The occurrence of SCI-induced SA in a large fraction of DRG neurons and the persistence of t

44 inergic amacrine cells colocalized DsRed and a large fraction of DsRed-expressing amacrine cells was

45 y and mutation analyses, we demonstrate that a large fraction of E2F3 target genes are synergisticall

46 ature of this catalyst mesostructure exposes a large fraction of edge sites, which, along with its hi

47 Results suggest that a large fraction of emissions and water consumption are

48 A large fraction of engineered nanomaterials in consumer

49 Since a large fraction of enhancers are now known to be transc

50 erial accreted by the Earth always comprised a large fraction of enstatite-type impactors (about half

51 e sequences derived from transposons make up a large fraction of eukaryotic genomes and must be silen

52 (TEs) are mobile DNA sequences that make up a large fraction of eukaryotic genomes.

53 historical and still commonly held view that a large fraction of fungi are exclusively clonal and tha

54 At present the functions of a large fraction of genes are unknown; improvements in s

55 ng these "population genomes." We discovered a large fraction of genes that are rare in each populati

56 Thus, a large fraction of genes that are silenced on the inact

57 In addition to finding eQTLs and aseQTLs for a large fraction of genes, we show that alleles at these

58 el mutations, which have been shown to cause a large fraction of genetic diseases.

59 Although a large fraction of genetic variants were not detected b

60 Deep sequencing analyses have shown that a large fraction of genomes is transcribed, but the sign

61 Recent findings indicate that a large fraction of genomic GR binding coincides with ch

62 pressure (IOP) has been proven beneficial in a large fraction of glaucoma patients.

63 ed multispecies fisheries (which account for a large fraction of global fish catch) may result in dec

64 A large fraction of GNRs with bent and smooth edges was

65 Cdh23 cytoplasmic binding protein harmonin, a large fraction of harmonin became colocalized with Cdh

66 d difference between the variants, targeting a large fraction of hdeltaOR-Cys(27) to ERAD.

67 s shows strong theta rhythmicity of spiking, a large fraction of head-direction selectivity (50%, 34

68 mors displaying urea cycle defects including a large fraction of hepatocellular carcinomas, metastati

69 at the polymer-wrapped nanoparticle contains a large fraction of highly mobile polymer segments, impl

70 n suggested that the coordinated activity of a large fraction of hippocampal cells at the goal locati

71 We found that a large fraction of hippocampal neurons, in both bat spe

72 mpensation in the fly and is responsible for a large fraction of histone H4 lysine 16 (H4K16) acetyla

73 A large fraction of holes are made in a periodic pattern

74 We identify PITPNC1 as a gene amplified in a large fraction of human breast cancer and overexpresse

75 We report here that in a large fraction of human breast cancers, the gene encod

76 KRAS mutated tumours represent a large fraction of human cancers, but the vast majority

77 ome numbers and recurrent aneuploidies drive a large fraction of human cancers, targeted therapies se

78 re that TrkC expression is down-regulated in a large fraction of human colorectal cancers, mainly thr

79 A large fraction of human complex trait heritability is

80 al expansion of hematopoietic progenitors in a large fraction of human myeloid malignancies.

81 sting that TF binding variation may underlie a large fraction of human phenotypic variation.

82 Although a large fraction of human protein-coding genes and lincR

83 Two recent genomic studies suggest that a large fraction of human tumors evolves in the presence

84 e presence of organics was observed, despite a large fraction of hydrocarbon-like SOA present in the

85 In fact, a large fraction of identified genes are annotated as ha

86 Over a wide range of collision energies, a large fraction of indirect scattering via a long-lived

87 Despite its high heritability, a large fraction of individuals with schizophrenia do no

88 tting mathematical models, we estimated that a large fraction of infected cells dies through abortive

89 sion of inhibition under promoters targeting a large fraction of inhibitory neurons may provide a per

90 A large fraction of innate NKTgammadelta T cells uses TC

91 n, and we suggest that such periods composed a large fraction of integrated time in the Turkana Basin

92 Our data indicate that a large fraction of internalized fluorescent tRNA (>70%)

93 ieved), or because they osmotically withdraw a large fraction of intracellular water prior to cooling

94 es devoted to polyketide synthesis making up a large fraction of its coding capacity.

95 biotic lifestyle, it almost invariably loses a large fraction of its genome [1, 2].

96 hage levels in mature adipocytes, PU.1 bound a large fraction of its macrophage sites, where it induc

97 rtex and cerebellum reveal the expression of a large fraction of known miRNAs with distinct profiles

98 We found that a large fraction of L1s were in high linkage disequilibr

99 hanide complexes in question, and likely for a large fraction of lanthanide complexes in general.

100 reference atlas for neuron subsets covering a large fraction of larval neurons.

101 We show that TLS contributes to a large fraction of lesion bypass and that it is mostly

102 is shows that the initiation stage comprises a large fraction of life (>70%).

103 due to transposable elements (TEs), makes up a large fraction of many genomes.

104 Thus, a large fraction of Mars' atmospheric gas has been lost

105 In contrast, a large fraction of MBC produced antibody that recognize

106 A large fraction of MBCs harbor defects in breast cancer

107 In late G1 phase, a large fraction of MCM proteins are loaded onto chromat

108 00E), to induce an active oncogenic state in a large fraction of melanomas, thyroid cancers, hairy ce

109 Transposable elements (TEs) occupy a large fraction of metazoan genomes and pose a constant

110 adon (up to 2.9 gm(-2)y(-1)) can account for a large fraction of methane emissions from this lake.

111 tion of imatinib with arsenic trioxide cured a large fraction of mice with MPNs.

112 oton imaging in living mice we observed that a large fraction of microemboli infused through the inte

113 A large fraction of microRNAs (miRNAs) are derived from

114 Another challenge is the fact that a large fraction of miRNAs are encoded within genes maki

115 A large fraction of mitochondrial proteins typically has

116 plex, with multiple intermediate states, and a large fraction of molecules go through intermediate st

117 y altered chemical potential that stabilizes a large fraction of monopole dimers.

118 Recent studies suggest that a large fraction of mRNAs localize to distinct cytoplasm

119 Electron microscopic analysis revealed that a large fraction of myofibers from 2-3-month-old MCK-bet

120 A large fraction of Nanog-interacting loci were bound by

121 bone marrow (BM) stromal cells characterizes a large fraction of Nestin(+) cells, containing most fib

122 rom visual cortex in awake animals show that a large fraction of neural activity is not predictable f

123 As expected, a large fraction of neurons (n = 170; 53%) had place fie

124 Rather, a large fraction of neurons did not perform any signific

125 Using multielectrode recording, we found a large fraction of neurons in early visual cortex with

126 oteasome inhibition approaches revealed that a large fraction of NM-II and myosin-1c molecules fail t

127 mplex genomic rearrangements can account for a large fraction of non-recurrent rearrangements at a gi

128 group (clade II) in the environment include a large fraction of nondenitrifying N2O reducers, which

129 nd attendant L chain receptor editing affect a large fraction of normal developing B cells.

130 In addition, a large fraction of novel promoters coincide with MaLR a

131 017) show that Drosophila embryos synthesize a large fraction of nucleotides on the go and that negat

132 protein thermodynamic stability accounts for a large fraction of observed mutational effects.

133 The assembled structures contain a large fraction of optoelectronically active material a

134 A large fraction of our genome consists of mobile geneti

135 tal data; for example, here, the presence of a large fraction of particles distributed as monomers an

136 nexpected clinical presentations occurred in a large fraction of patients with PHI and were associate

137 allergy as a public health issue by reaching a large fraction of patients.

138 bject-decoding performance and that removing a large fraction of "PIT" activity resulted in similar d

139 A large fraction of pONs is highly functionalized, posse

140 Despite a large fraction of previously inexperienced operators,

141 (N2)-fixing phytoplankton, which contribute a large fraction of primary production in the tropical a

142 Prophages represent a large fraction of prokaryotic genomes and often provid

143 ethods can assemble the correct topology for a large fraction of protein domains, such approximate mo

144 increased precision rate allows detection of a large fraction of protein structural relationships, th

145 a key structural and functional component of a large fraction of proteins.

146 y measurements of gene expression constitute a large fraction of publicly shared biological data, and

147 lies are typically fragmented and also leave a large fraction of reads unassembled.

148 SMC completely protects a large fraction of recipients, while intermittent preve

149 graphic and spectroscopic data revealed that a large fraction of recombinantly overexpressed AT retai

150 loropsis gaditana is capable of accumulating a large fraction of reduced carbon as lipids.

151 Many genomes contain a large fraction of repetitive DNA, much of which is mad

152 A large fraction of RepID-binding sites share a common G

153 ond group, PR but not ER was associated with a large fraction of RNA polymerase III-transcribed tRNA

154 ffectively drives the spiking-rate signal of a large fraction of S1 cortical neurons.

155 responsible for the protection and burial of a large fraction of sedimentary organic carbon (OC).

156 In addition, we noticed that a large fraction of seeds from mpk6 single-mutant plants

157 Surprisingly, a large fraction of sensory neurons performed little if

158 eatures of serotonergic neuron activity: (1) a large fraction of serotonergic neurons modulated their

159 ction sites will require mitigation steps at a large fraction of sites.

160 te that hydrothermally derived iron sustains a large fraction of Southern Ocean export production.

161 hanisms and STARD4 in particular account for a large fraction of sterol transport between the plasma

162 ion in individual cells, we demonstrate that a large fraction of stochastic allele-specific expressio

163 olivine that form interconnected bands where a large fraction of strain is accommodated.

164 uggest that synaptic dysfunction may mediate a large fraction of strong, individually rare genetic in

165 ul for the atom-level modeling and design of a large fraction of structurally uncharacterized TMH pro

166 A large fraction of submicron atmospheric aerosol partic

167 f the elderly in the Southeastern USA, where a large fraction of subpopulation resides.

168 of all live births in the Western world, yet a large fraction of such defects have an unknown etiolog

169 recombination and permits the collection of a large fraction of sunlight.

170 Furthermore, a large fraction of synapses are positive for phospho-Gl

171 They target a large fraction of T cell pools to set in motion a "cyt

172 Therefore, the conservation of a large fraction of T-cell epitopes suggests that the se

173 SFMBT1, LSD1, and CoREST share a large fraction of target genes, including those encodi

174 ino acid frequency; these correctly classify a large fraction of test cases with a high degree of spe

175 These experiments revealed that a large fraction of TF binding events occur in regions w

176 interactions, we found that genes that share a large fraction of TF interactions are more likely to b

177 ly bound sigma complex on IrO2(110) and that a large fraction of the adsorbed complexes underwent C-H

178 The fact that a large fraction of the annotations in current biologica

179 The circadian clock modulates expression of a large fraction of the Arabidopsis genome and affects m

180 t by showing that in Caenorhabditis elegans, a large fraction of the behavioral effects of amphetamin

181 A large fraction of the carbon dioxide added to the atmo

182 A large fraction of the cells present at the peak of exp

183 Disruption of PakA in pten- cells restored a large fraction of the cells to normal behavior.

184 Surprisingly, a large fraction of the chromophore produced by dihydroc

185 Intracellular MTs carry a large fraction of the compressive loads sensed by the

186 cogen as massive perinuclear deposits, where a large fraction of the detectable Stbd1 co-localized.

187 1/2 inhibitor (AZD6244) induced apoptosis in a large fraction of the dormant cells and delayed metast

188 to identify polymorphisms that could explain a large fraction of the dose variance.

189 is imperiled status, is the disappearance of a large fraction of the Earth's amphibians inevitable, o

190 and dendritic regions of hippocampal neurons a large fraction of the fluorescent signal originates fr

191 humidity tends to suppress it; additionally, a large fraction of the gas is released within the first

192 A large fraction of the genes from sequenced organisms a

193 ot dominate the phage genomic landscape, and a large fraction of the genes in phage genomes maintain

194 We find that a large fraction of the genes that change in expression

195 Because of this a large fraction of the genetic architecture of many com

196 ity of transposable elements that constitute a large fraction of the genome (up to 90%).

197 Although a large fraction of the genome can be characterized as e

198 ur analysis predicts that, in the long term, a large fraction of the genome is affected by short epis

199 rasite evolution is impeded by the fact that a large fraction of the genome is either highly repetiti

200 Transcriptome profiling studies suggest that a large fraction of the genome is transcribed and many t

201 ot adequate to produce genotype calls across a large fraction of the genome with acceptably low error

202 oncentrated in very localized areas, whereas a large fraction of the globe is not influenced by the e

203 age, and phylogenetic analysis revealed that a large fraction of the H. dujardini genome is derived f

204 A large fraction of the heritability of plasma lipids is

205 ses, rare alleles are unlikely to contribute a large fraction of the heritable variation, and therefo

206 Nonetheless, a large fraction of the human MT family remains poorly c

207 nt strategy that enables the virus to impact a large fraction of the human population.

208 that lack a unique 3D structure and comprise a large fraction of the human proteome play important ro

209 e Nansen Ice Shelf in Antarctica that export a large fraction of the ice shelf's meltwater into the o

210 It has been proposed that a large fraction of the initial oxide can be surprisingl

211 articles provides the opportunity to deliver a large fraction of the injected dose to insonified tumo

212 , 8.2-10.9 per thousand, which indicate that a large fraction of the inorganic phosphate in this soil

213 ngly, the multiplicative model could explain a large fraction of the interindividual variability by v

214 called keystone complex required to assemble a large fraction of the kinetochore.

215 Flexible filamentous viruses make up a large fraction of the known plant viruses, but in comp

216 We find that a large fraction of the lncRNAs expressed in cells from

217 anisms, such as yeast, have failed to detect a large fraction of the loci that underlie such complex

218 A large fraction of the luminal volume of the granal thy

219 A large fraction of the mammalian genome is organized in

220 A large fraction of the mammalian genome is transcribed

221 g endogenous retroviruses (ERVs), constitute a large fraction of the mammalian genome.

222 of a combination of two main factors: first, a large fraction of the massive high-redshift galaxy pop

223 nds of metabolites, allowing the analysis of a large fraction of the metabolome and focused analysis

224 ls to barely detectable levels Surprisingly, a large fraction of the mice survive to adulthood with l

225 dence for a picture of the Universe in which a large fraction of the missing baryons reside in the fi

226 However, a large fraction of the most enriched aptamers in System

227 st growth and high fixation, fixers provided a large fraction of the nitrogen needed to support net f

228 at orbital migration of giant planets ejects a large fraction of the original planetesimals into inte

229 gate surfaces at the Taj Mahal indicate that a large fraction of the outer Taj Mahal surfaces are cov

230 Peroxides account for a large fraction of the oxidant flux, possibly eclipsing

231 In the absence of apo-acceptors, a large fraction of the oxidized holo-mNT form is conver

232 ly important in settings where RTEs comprise a large fraction of the peripheral T cell pool, such as

233 ociated with quantitative traits and explain a large fraction of the phenotypic variance.

234 Climate disruptions may cause the loss of a large fraction of the planet's biodiversity, even if t

235 the moment of ATP/GroES addition reveal that a large fraction of the population shows the opposite be

236 Even though a large fraction of the pore space is occupied with char

237 other major environmental Ags that represent a large fraction of the preexisting memory B compartment

238 At all stages, a large fraction of the progenitors are multipotent.

239 A large fraction of the proteins that are being identifi

240 tterns of DNA content and cyclin expression, a large fraction of the proteome changes detected in arr

241 One way to avoid the waste of a large fraction of the radiation emitted from hot objec

242 This approach fails to analyse a large fraction of the rare variants present in the ent

243 A large fraction of the regulatory genes predicted by th

244 at such an approach is capable of uncovering a large fraction of the regulatory map of a genome even

245 ssemblies contain a single scaffold covering a large fraction of the respective genomes, suggesting t

246 Furthermore, a large fraction of the sample is often lost during samp

247 abile compounds bonding to minerals comprise a large fraction of the SOM.

248 A large fraction of the spermine present in cells is bou

249 While these methods can detect a large fraction of the spikes from a recording, they ge

250 efined enzymatic reactions and may represent a large fraction of the structurally unidentified metabo

251 burst in June, which led to the discharge of a large fraction of the subsurface ocean heat.

252 ithin a neuron's receptive field filters out a large fraction of the suppression induced by distracte

253 hich are known to be inhibitory, represented a large fraction of the surviving cells.

254 ween a regime in which the contagion affects a large fraction of the system and one in which only a s

255 DN T cells also made up a large fraction of the T cell compartment in human kidn

256 sity of several pMHC, they can be rescued by a large fraction of the Tfh cell repertoire in the germi

257 n-based technologies are capable of removing a large fraction of the total contaminant mass, and redu

258 ess change in individual lines revealed that a large fraction of the total decay in fitness (42.3%) w

259 issolved organic nitrogen (DON) accounts for a large fraction of the total nitrogen discharged to sur

260 Individually, for a large fraction of the traits, their predictive accurac

261 Carbohydrates comprise a large fraction of the typical diet, yet humans are onl

262 irection, whereas SKAT is more powerful when a large fraction of the variants in a region are noncaus

263 We confirm that a large fraction of the variation in this classic quanti

264 1.5 to 4.5 degrees Celsius), indicating that a large fraction of the warmth of the early Eocene green

265 A large fraction of the world grasslands and savannas ar

266 Because a large fraction of the yeast binary interactome remains

267 Colloidal quantum dots (QDs) have a large fraction of their atoms arrayed on their surface

268 only in multicellular organisms that compact a large fraction of their DNA.

269 (sRNAs) to repress or activate expression of a large fraction of their proteome.

270 n were compared to identify regions that use a large fraction of their renewable local water supply.

271 excess to RNA replication intermediates, and a large fraction of them are not involved in RNA synthes

272 ta had the potential to oxidize ammonia, and a large fraction of them had urease genes, enabling the

273 We found that a large fraction of them involve cell-to-cell communicat

274 ns at endogenous expression levels and found a large fraction of them localising to subcellular compa

275 nt physiological signals and are targets for a large fraction of therapeutic drugs.

276 rimental data in isolation and we found that a large fraction of these agents alter cell viability.

277 In grape (Vitis vinifera), a large fraction of these compounds is present as nonvol

278 degree of parental mosaicism indicating that a large fraction of these de novo mutations occurred dur

279 A large fraction of these genes encode transcription fac

280 Simulations suggest that a large fraction of these misfolds resemble an intramole

281 We found that a large fraction of these neurons have nonoriented respo

282 A large fraction of these predicted genes were recovered

283 havior of IDPs in light of the evidence that a large fraction of these proteins possess a specific pr

284 previously discovered imprinted transcripts; a large fraction of these represent novel noncoding RNAs

285 A large fraction of these SP cells are CD44 and CD24 pos

286 ctivation in the centre of transformation in a large fraction of these tumours.

287 A large fraction of this gas ( approximately 42%) may re

288 s in mice, providing a resource for studying a large fraction of this important class of drug target.

289 that is years-to-decades old, which makes up a large fraction of total soil carbon in forest soils gl

290 ated view of genome-wide transcription where a large fraction of transcripts emanates from unannotate

291 de Bruijn graphs, Trinity fully reconstructs a large fraction of transcripts, including alternatively

292 Macrophages rapidly removed a large fraction of transfused platelets independent of

293 Cellulosic crops are projected to provide a large fraction of transportation energy needs by mid-c

294 Genome-wide CAGE studies reveal that a large fraction of TSS exhibit peaks where the vast maj

295 -genome sequencing, we provide evidence that a large fraction of unsolved exome cases have underlying

296 tle outbreaks killing millions of trees over a large fraction of western United States (US) forests.

297 mammalian genome is extensively transcribed, a large fraction of which is divergent transcription fro

298 Oscillations in patterns of expression of a large fraction of yeast genes are associated with the

299 time interaction that affected expression of a large fraction of yeast genes.

300 the following properties: it is sparse, with a large fraction of zero synaptic weights ('potential' s