1 Ns (OR = 3.7; 95% CI = 3.1-4.3) and provides
a model whereby a constitutional genetic factor is assoc
2 Thus, our findings are consistent with
a model whereby a distorted estimation of the gain cue u
3 Our results are compatible with
a model whereby a genetic variant in pri-mir-30c-1 leads
4 Our data support
a model whereby a hot L1 source element on Chromosome 17
5 The data support
a model whereby a hydrophobic patch on the ProTx-II surf
6 ased upon our collective results, we propose
a model whereby a newly exported, partially folded inter
7 In summary, we provide
a model whereby a novel interplay between RNA-binding, R
8 Additional biochemical experiments support
a model whereby a single Ca(2+)/CaM bridges the C-termin
9 These findings suggest
a model whereby a switch in the duration of CDK1 activat
10 This study can act as
a model whereby a universal housekeeping enzyme may be a
11 This work supports
a model whereby ABA-triggered stomatal closure requires
12 We believe our results support
a model whereby acidic pH, high ionic strength, or expos
13 We propose
a model whereby activated Fgfr signals through Ras-MAPK
14 These data support
a model whereby activating MLLT1 mutations early in rena
15 Together, these results support
a model whereby afadin determines lumen placement by dir
16 preferred substrate for dFic, thus endorsing
a model whereby AMPylation regulates the function of BiP
17 We present
a model whereby an unknown cue causes dimerization of th
18 Together our data support
a model whereby antiviral RNAi competes with endogenous
19 Our results support
a model whereby AnxA2 limits the availability of TRPA1 c
20 The results support
a model whereby apo-AcnB directly interacts with the pgd
21 We present
a model whereby ARC6 relays information on stromal FtsZ
22 Together, these data support
a model whereby arginine methylation modulates dynamic a
23 Our data support
a model whereby ASB2 contributes to hematopoietic differ
24 Our results support
a model whereby Ascl1 integrates inputs from both stimul
25 Therefore, our data are consistent with
a model whereby augmented and or prolonged presentation
26 These data support
a model whereby autoreactive plasma cells (at least cert
27 On the basis of these findings, we propose
a model whereby B cells contribute to arthritis in mice,
28 We propose
a model whereby B. anthracis LCPs promote attachment of
29 These data are consistent with
a model whereby BCL6 can directly silence oncogenes in G
30 Taken together, these data suggest
a model whereby bile salts or other detergents destabili
31 Our results are consistent with
a model whereby binding of HIV-1 Gag to phosphoinositide
32 ly enhanced RhoGAP activity, consistent with
a model whereby binding of Rac1 relieves autoinhibition
33 We propose
a model whereby binding of synaptotagmin-1 to the SNARE
34 ne of polarized epithelial cells and propose
a model whereby binding of the LRR to proteins at the ta
35 We propose
a model whereby BRCA1 impacts on 53BP1 to allow access o
36 These data suggest
a model, whereby BRCA1 is present on defined promoters a
37 Our combined results support
a model whereby BTLA on CD4(+) T cells and additional in
38 Our results support
a model whereby calcium-dependent TSLP release by kerati
39 These findings support
a model whereby calcium-induced modification of PICK1 st
40 These results present us with
a model whereby CaM is spatially modulated by target pro
41 Overall, the data provide clear support for
a model whereby capsid assembly within the maturing viri
42 Together, our data strongly support
a model whereby CASK recruits FRMD7 to the plasma membra
43 Therefore, our overall results reveal
a model whereby CD1d-mediated Ag presentation is negativ
44 These results are consistent with
a model whereby CDKN2A loss affects a range of different
45 Furthermore, they are consistent with
a model whereby Cdo serves as a multifunctional corecept
46 We present
a model whereby CELF1 regulates APA site selection follo
47 We thus propose
a model whereby cell surface ubiquitination precedes end
48 These findings align with
a model whereby cells respond similarly to an equivalent
49 We propose
a model whereby centrosome-associated SYS-1 degradation
50 These data support
a model whereby centrosome-MT interactions during interp
51 Our data support
a model whereby CFS expression during cellular stress is
52 The authors propose
a model whereby CFTR-mediated bicarbonate secretion must
53 a interaction with Borealin, which suggested
a model whereby CHMP4C inhibits abscission upon phosphor
54 Our data support
a model whereby clinically or host-relevant signals medi
55 f specific cerebellar subregions, supporting
a model whereby compensatory morphological changes suppo
56 This trend is consistent with
a model whereby conduction occurs by two different mecha
57 These findings support
a model whereby cotranscriptional recruitment of Rnf20 a
58 ic repeat (CRISPR) subtypes have resulted in
a model whereby CRISPRs function as a defense system aga
59 These findings suggest
a model whereby cytokine deficiency leads to oncogenic i
60 The results support
a model whereby Dab2 acts as a multifunctional adaptor i
61 Taken together, we present
a model whereby Dbp2 functions to cotranscriptionally mo
62 We propose
a model whereby de novo J insertion is mediated by JBP2.
63 We present
a model whereby defects in Suv3p result in accumulation
64 stem and neural progenitor cells, suggesting
a model whereby developmentally regulated transcription
65 Based on these results, we propose
a model whereby Dex- and Mstn-mediated atrophic signals
66 Our data suggest
a model whereby dFMRP is neuroprotective by remodeling T
67 We propose
a model whereby DGAT1 serves as a cellular hub for HCV c
68 We propose
a model whereby direct inputs of Nanog and Hoxa1 on shar
69 These findings suggest
a model whereby display of multiple capsular polysacchar
70 We propose
a model whereby distinct activity states of Rap1 modulat
71 l distinctions from Lgr5(+) ISCs and support
a model whereby distinct ISC populations facilitate home
72 These results give rise to
a model whereby distinct MT-bound and actin-nucleating p
73 We propose
a model whereby dMCRS2 promotes gene transcription by fa
74 The data fit
a model whereby DNA polymerases work sequentially to byp
75 These data suggest
a model whereby DOT1L-dependent lysine 79 of histone H3
76 for OCRL1 in neural development, and support
a model whereby dysregulation of phosphoinositide metabo
77 coupled with recent structural data, suggest
a model whereby early phosphorylations promote initiatio
78 These results support
a model whereby EDEM1 binds nonnative proteins and uses
79 We propose
a model whereby eEF1A binds to Rho1p-GDP on the vacuolar
80 Overall, our results support
a model whereby EFA6 recruits endophilin on flat areas o
81 Our results support
a model whereby emergent metabolites signal a beneficial
82 Collectively, these data support
a model whereby emerin facilitates repressive chromatin
83 Together, these data support
a model whereby engagement of leukocyte PECAM induces it
84 We propose
a model whereby enhancer binding by Sall4 and other plur
85 We propose
a model whereby Esa1 and Rpd3L act coordinately to contr
86 These findings support
a model whereby estradiol acts by activation of PI3K/Akt
87 These findings support
a model whereby estradiol acts via the IGF-1 receptor to
88 The data support
a model whereby failure of this pathway results in ectop
89 Our results support
a model whereby FAK-mediated FA remodeling may occur thr
90 tions, and buffering experiments all support
a model whereby fast Nav channel-mediated dSpikes (Na-dS
91 These data support
a model whereby FMRP controls germline proliferation by
92 Our data suggest
a model whereby force acting on integrin-talin complexes
93 Our data point to
a model whereby FOX transcription factors control gene e
94 These results strongly support
a model whereby FOXM1 is specifically recruited to chrom
95 ished FoxO1 as a "pioneer" factor, suggested
a model whereby FoxO1 chromatin remodeling at regulatory
96 Our data support
a model whereby full-length PA-LAP is activated in a two
97 In light of our findings, we posit
a model whereby functional nucleolytic activity is not t
98 mammalian mRNA export machinery and suggest
a model whereby GANP facilitates the transfer of NXF1-co
99 Therefore, these data support
a model whereby geminin promotes the neuronal precursor
100 lin as demonstrated by analysis according to
a model whereby ghrelin is a partial agonist with respec
101 mma-secretase complex maturation, we present
a model whereby Glu-333 can serve a dual role via simila
102 Our results support
a model whereby Gpd1 may be imported as a monomer or a d
103 We propose
a model whereby Gqalpha signaling differentially regulat
104 We propose
a model whereby group I PAKs act downstream of Rac to or
105 Our findings are consistent with
a model whereby h3/acidic calponin controls fibroblast m
106 The new evidence proposes
a model whereby HMGA2 directly induces multiple transcri
107 These data support
a model whereby HP1 takes part in multiple mechanisms of
108 With the majority of current data supporting
a model whereby HSCs derive from arterial endothelium, o
109 These data suggest
a model whereby HTLV-1 infection augments the number of
110 These results support
a model whereby IFNG uses cis-regulatory elements with c
111 These data support
a model whereby Ikaros directly activates Th2 gene expre
112 These results support
a model whereby IL-22RA1 enhances host-microbiota mutual
113 ain (CD127) and endocytosis, consistent with
a model whereby IL-7 is internalized via receptor intera
114 Together, our data support
a model whereby impaired mitochondrial [Fe-S] cluster bi
115 The data support
a model whereby inactivation of specific regulatory elem
116 This is consistent with
a model whereby increased COL1A1 transcription predispos
117 We propose
a model whereby increased enzyme flexibility facilitates
118 Our data are consistent with
a model whereby increased levels of Pif1 interfere with
119 Together, our data set forth
a model whereby increased secretion of Hsp90 in the cran
120 Together, our results support
a model whereby increased tooth number and an accelerate
121 These results support
a model whereby information about rewards signaled in PF
122 a074Me, suppresses this response, supporting
a model whereby ingested particles disrupt lysosomes and
123 These findings are consistent with
a model whereby inhibition of Ang2 leads to normalizatio
124 n the antagonistic phase, we instead propose
a model whereby inhibitory coupling via postinhibitory r
125 Our study provides
a model whereby insights into the ancient history of vir
126 We propose
a model whereby insufficient levels of vitamin D, EPA, o
127 Our results support
a model whereby insulin promotes exocytic flux primarily
128 er with previous results, these data support
a model whereby insulin stimulates TUG cleavage to liber
129 lation regulates mTORC1 function and suggest
a model whereby insulin-stimulated mTOR S1261 phosphoryl
130 We present a hypothesis consistent with
a model whereby intrahepatic CD8 TCM cells, being mainta
131 Together, these experiments support
a model whereby JIP1 coordinates APP transport by switch
132 transcription rate and Sen1 activity support
a model whereby kinetic competition between elongating P
133 This suggests
a model whereby KSHV alters ICN-RBPjkappa gene regulatio
134 PUFA in nuclei of living cells and suggested
a model, whereby L-FABP facilitated VLC-PUFA targeting t
135 We propose
a model whereby LcrH-dependent association of YopD with
136 of PNs as a teaching signal, consistent with
a model whereby learning leads first to reductions in PN
137 and targeted gene disruption studies support
a model whereby limited cleavage of alpha-mannan on the
138 These findings suggest
a model whereby linked metabolic-epigenetic programs are
139 Our data support
a model whereby Lmo0644 acts as an LTA primase LtaP and
140 These data support
a model whereby local geometry constrains the orientatio
141 Our findings are consistent with
a model whereby low, intermediate, and high CD122 signal
142 Our data suggest
a model whereby Lrp4 modulates Wnt/beta-catenin signalin
143 Data presented here support
a model whereby LT-mediated activation of Nlrp1b and sub
144 These data support
a model whereby LTA backbone synthesis proceeds in S. au
145 These data support
a model whereby Lys-120 acetylation contributes to both
146 We therefore propose
a model whereby MA trimerization is required to form a l
147 Therefore, the present data support
a model whereby MCL-1 depletion increases 53BP1 and RIF1
148 In this study, we present evidence for
a model whereby melanophores and iridophores descend fro
149 We provide
a model whereby messenger ribonucleoprotein (mRNP) assem
150 This supports
a model whereby MIF expression in neuroblastoma initiate
151 We propose
a model whereby minus-end microtubule stabilization medi
152 These results suggest
a model whereby MITD1 coordinates the activity of ESCRT-
153 We propose
a model whereby Mps1 transphosphorylation results in its
154 We propose
a model whereby mTOR kinase domain phosphorylation modul
155 Our results support
a model whereby MTX inhibits reduction of dihydrobiopter
156 From these results, we propose
a model whereby multi-site cdk-dependent phosphorylation
157 Our data support
a model whereby multiple features of HLA-DR are involved
158 We propose
a model whereby multiple infections per cell lead to red
159 These findings are consistent with
a model whereby multiple NLR inflammasomes attenuate dis
160 Our data support
a model whereby multiple Twist1 activity thresholds cont
161 ther with previous studies, our data support
a model whereby Munc18-1 acts as a template for SNARE co
162 Our data lead to
a model whereby myosin VIII links phragmoplast microtubu
163 Our data support
a model whereby nascent NepR(IDR)-PhyR interactions and
164 ms of F. tularensis phagocytosis and support
a model whereby natural IgM binds to surface capsular an
165 nance of the spermatogonial pool and propose
a model whereby negative feedback from mTORC1 to the GDN
166 Together, the results of this study support
a model whereby neural organization at key stages of dev
167 These results suggest
a model whereby Neuralized1-dependent ubiquitination fac
168 it?" decisions; out of this work has emerged
a model whereby neurons accumulate information about the
169 We propose
a model whereby NKB and dynorphin act autosynaptically o
170 Our data support
a model whereby NLS-RecA-Gal4 DNA filaments bind to comp
171 teoblast mechanotransduction, and we propose
a model whereby NO/cGMP/PKG II-mediated Erk activation a
172 We propose
a model whereby nuclear pore complexes either compete wi
173 Our results are consistent with
a model whereby OA neuronal signaling increases after co
174 Collectively, these data support
a model whereby OA/Gpnmb acts as a negative regulator of
175 We, therefore, propose
a model whereby ORF57 interacts directly with PYM to enh
176 removed from the Rac1 interface, supporting
a model whereby P-Rex1 binding to PIP3 and/or Gbetagamma
177 Collectively, these data favor
a model whereby P. graminicola coopts the plant BR pathw
178 These observations give rise to
a model whereby papillomavirus oncoproteins, including B
179 These data support
a model whereby PDE10A trafficking and localization can
180 Based on our findings, we propose
a model whereby Pdx1 and BETA2/NeuroD1 physically intera
181 We propose
a model whereby persistence of long-term memory results
182 tly, genetic and molecular evidence supports
a model whereby PHF8 regulates zebrafish neuronal cell s
183 These data support
a model whereby PhoB becomes activated at a late stage o
184 phatidylinositol, inhibits TRPV1, supporting
a model whereby phosphoinositide turnover contributes to
185 Our data support
a model whereby phosphorylation increases structural fle
186 Our data support
a model whereby PLD1 regulates Rap1 activity by controll
187 Our data support
a model whereby postnatal loss of hair forming ability i
188 These results suggest
a model whereby posttermination ribosomes/ribosomal subu
189 These results indicate
a model whereby Pou3f4 in the otic mesenchyme establishe
190 These data are consistent with
a model whereby PP M cells are the primary route by whic
191 We propose
a model whereby PRC1 acts in concert with specific lncRN
192 Our data suggest
a model whereby,
prior to hair initiation, proximally lo
193 We describe
a model whereby promoter demethylation requires the co-i
194 We propose
a model whereby PTIP stabilizes the Pax5 DNA interaction
195 These results are consistent with
a model whereby PV and HRV disrupt nucleo-cytoplasmic tr
196 Our data support
a model whereby QscR polypeptides fold properly in the a
197 n of Spag with both Hsp70 and Hsp90 suggests
a model whereby R2TP would accompany clients from Hsp70
198 We propose
a model whereby RAPGEF5 activates the nuclear GTPases, R
199 The studies also support
a model whereby receptor expression is limited by cell d
200 These findings support
a model whereby repeat expansions elicit cellular stress
201 These results suggest
a model whereby retinoic acid signaling regulates Lhx8 a
202 We propose
a model whereby reversible phosphorylation of Ikaros at
203 These results support
a model whereby RPA, best known for its role in DNA repl
204 The results are consistent with
a model whereby RTNLB1 and RTNLB2 regulate the transport
205 We propose
a model whereby Sar1 dimers assemble into ordered arrays
206 They also support
a model whereby selection for the ability to mount a bro
207 Mechanistically, we propose
a model whereby SETX attenuates the activity of RNA poly
208 We therefore propose
a model whereby ShcD competes with neurotrophic receptor
209 o the 5' or 3' ends of P4R2 RNAs, suggesting
a model whereby siRNAs are generated from either end of
210 Our results favor
a model whereby Slit2 binding to a Robo1/Robo4 heterodim
211 Together, these findings favor
a model whereby SLR1 acts as a positive regulator of hem
212 These data suggest
a model whereby SM, a viral protein, recruits and co-opt
213 Our findings suggest
a model whereby small perturbations in a self-reinforcin
214 This study supports
a model whereby SMN deficiency impedes transport and loc
215 ine diseases generally, the findings support
a model whereby specific neuronal circuits suffer insult
216 We propose
a model whereby stable chromatin binding protects the Fo
217 Altogether, the data support
a model whereby stereocilia actin cores are largely stat
218 These data support
a model whereby STIM1 is critical to deactivate a key ne
219 Our results are consistent with
a model whereby Stn2 is required to preserve SV protein
220 te immune signal transduction and then offer
a model whereby structurally distinct proteins can be gr
221 Our results support
a model whereby subcellular anchoring of CaN by AKAP150
222 These findings suggest
a model whereby sumoylation of Rad1 promotes its disenga
223 We previously described
a model whereby suppression drives a Drosophila grooming
224 Our results support
a model whereby swelling and proinflammatory signals ass
225 We propose
a model whereby switching between monomeric and dimeric
226 These findings support
a model whereby synapsin accumulates at sites of synapti
227 We propose
a model whereby TBC1D14 and TRAPPIII regulate a constitu
228 We thus propose
a model whereby TbDCL2 fuels the T. brucei nuclear RNAi
229 We propose
a model whereby territory size is determined by the numb
230 These observations are consistent with
a model whereby TFB3 activates general transcription in
231 These data support
a model whereby TGB protein interactions function in the
232 The data are consistent with
a model whereby the 3'-end of the tRNA remains free to s
233 Together, these experiments support
a model whereby the A(2A)AR can prime JAK-phosphorylated
234 Our results support
a model whereby the activation of Stat3 in the early sta
235 We propose
a model whereby the amide side chain is first required t
236 We present
a model whereby the amorphous nature of the aggregates r
237 Taken together, our results support
a model whereby the amphipathic helix in SM N100 attache
238 Our results support
a model whereby the C-terminal end of the Hendra virus F
239 Our findings support
a model whereby the cell cycle machinery not only contro
240 These observations point to
a model whereby the coiled-coil domain plays a key role
241 Based on these studies, we propose
a model whereby the concerted recruitment of CHMP4B and
242 We propose
a model whereby the CTD of VgrG-5-, propelled by T6SS-5-
243 Our data support
a model whereby the degree of apoptosis induction is reg
244 the binocular matching process, and suggest
a model whereby the dominant input instructs the develop
245 We therefore propose
a model whereby the downregulation of the NPM mRNA, medi
246 We propose
a model whereby the function of Ikaros is controlled by
247 These findings suggest
a model whereby the genomic vRNA serves as a switch to r
248 Our results support
a model whereby the high-fidelity replicative DNA polyme
249 These data suggest
a model whereby the Hsp70-Hsp110 chaperone complex antag
250 We propose
a model whereby the instantaneous rates of surface and v
251 We propose
a model whereby the intestinal genes aex-4 and aex-5 con
252 Based on these results, we propose
a model whereby the light- and day length-dependent inte
253 We propose
a model whereby the LysM domain ensures septal localizat
254 in filaments in anaphase, these data support
a model whereby the Myo19 actin-based motor helps to con
255 en together, our results are consistent with
a model whereby the NaStEP and NaSIPP interaction, in in
256 Our findings support
a model whereby the NLRP3 inflammasome, acting as an ext
257 These findings suggest
a model whereby the normal role of SAPAP3 is to inhibit
258 arify the roles of pax8 and sox3 and support
a model whereby the otic placode forms first and induces
259 A model whereby the protoxin undergoes a conformational
260 These findings best fit
a model whereby the Q(o) and Q(i) sites of the cyt bc(1)
261 These data suggest
a model whereby the RAG signal end complex is stabilized
262 These results support
a model whereby the regulation of ERalpha transcription
263 Our combined data support
a model whereby the risk variant augments the BCR and co
264 These findings support
a model whereby the Rs1 protein binds to PS in the retin
265 We propose
a model whereby the S. aureus Deltalcp mutant, defective
266 These findings support
a model whereby the selective removal of Nup FG repeat d
267 These data support
a model whereby the SLC16A12 (c.643C>T) mutation causes
268 not detectable in infected cells, we propose
a model whereby the species recruited to assembling VLPs
269 age of the upstream substrate helix suggests
a model whereby the structural dynamics of the VS ribozy
270 Our results support
a model whereby the SV5 promoter has evolved to function
271 Our data support
a model whereby the trafficking machinery plays an impor
272 This suggests
a model whereby the transcriptional activity of AIB1 is
273 We propose
a model whereby the uncoupling of protein levels of biog
274 These data support
a model whereby these two functionally distinct alloster
275 Based on these observations, we posit
a model whereby these two motors generate forces that at
276 We present
a model whereby this inhibition permits the muscle-deriv
277 In all, this work suggests
a model whereby this self-association stimulates the aut
278 Our observations also support
a model whereby tissue organisation and cell division ar
279 ion in response to LPS treatment, suggesting
a model whereby TLR signaling causes the phosphorylation
280 Our results support
a model whereby TOP1 and TOP2 act in separate pathways t
281 Our genetic and biochemical studies support
a model whereby Top1p recruits Sir2p to the rDNA and cla
282 We propose
a model whereby transcription factors activate lincRNAs
283 However, strong indirect evidence favors
a model whereby transendocytosis of the Notch extracellu
284 These data are consistent with
a model whereby Trp-76 anchors the C terminus of the cyt
285 Overall, our results support
a model whereby TRPV4 differentially regulates cell volu
286 We propose
a model whereby uncleaved alpha2delta subunits maintain
287 These data lead us to propose
a model whereby unique and additive activities of FGFR1
288 Our data support
a model whereby VAI functions as a PKR inhibitor because
289 Importantly, our data support
a model whereby VEGF regulates differentiation through a
290 We propose
a model whereby vhs-mediated destruction of SG mRNA prom
291 Based upon this data, we propose
a model whereby vimentin promotes FAK stabilization thro
292 Overall our data promote
a model whereby vinculin controls the transmission of in
293 The results corroborate
a model whereby X. oryzae pv. oryzae enhances the releas
294 These data are consistent with
a model whereby XRCC4/XLF complexes hold DNA ends togeth
295 he acetylation state of histones and provide
a model whereby yeast spliceosome assembly is tightly co
296 These results suggest
a model whereby Yku70 sumoylation upon DNA association s
297 We propose
a model whereby Yra1 terminates a cycle of mRNP assembly
298 ivity of PP4 during meiotic prophase suggest
a model whereby Zip1-S75 phosphorylation dynamically des
299 We propose
a model whereby zipcoded mRNP and/or tER ligands couple
300 tight junction (TJ) protein ZO-1, leading to
a model whereby ZO-1 acts by sequestering DbpA at the TJ