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1 ion in CCRCC and demonstrate this pathway to a potential therapeutic target.
2 ncer, thereby establishing the microbiota as a potential therapeutic target.
3 ression, and suggest TP63 gene regulation as a potential therapeutic target.
4 signaling in glioma and identify Vasorin as a potential therapeutic target.
5 A (miRNA) biology is of great importance and a potential therapeutic target.
6 er functional experiments to clarify AHSG as a potential therapeutic target.
7 abetogenic CB1R signaling in macrophages and a potential therapeutic target.
8 easts prompts future evaluation of Asp f3 as a potential therapeutic target.
9 iac surgery-associated AKI, and with HO-1 as a potential therapeutic target.
10 a KSHV restriction factor that can serve as a potential therapeutic target.
11 a-associated microglia/macrophages (GAM), is a potential therapeutic target.
12 ut the antihypertrophic myokine myostatin is a potential therapeutic target.
13 s an attractive tumor-associated antigen and a potential therapeutic target.
14 cal ligation and puncture in mice, making it a potential therapeutic target.
15 tilization as a metabolic feature of AML and a potential therapeutic target.
16 e clinically relevant to the study of RON as a potential therapeutic target.
17 duce cytotoxicity, suggesting that DEPTOR is a potential therapeutic target.
18 ribute to the pathogenesis of IPF and may be a potential therapeutic target.
19 d to noncanonical activation of STAT3 and as a potential therapeutic target.
20 gastric, and ovarian tumors, where it offers a potential therapeutic target.
21 ating, there is growing interest in LOX-1 as a potential therapeutic target.
22 ion of IL-1R/MYD88 signaling might represent a potential therapeutic target.
23 eness in OSCC and identify S1P signalling as a potential therapeutic target.
24 mmation by macrophages that could constitute a potential therapeutic target.
25 nt of convergence between these pathways and a potential therapeutic target.
26 ealthy brain aging and pointing to FKBP1b as a potential therapeutic target.
27 eases, cancer, and neuropathies, making TRiC a potential therapeutic target.
28 The correction of missplicing is a potential therapeutic target.
29 has been considered an oncogenic driver and a potential therapeutic target.
30 umor growth inhibition and points to Lat1 as a potential therapeutic target.
31 dulation of cellular molecular chaperones is a potential therapeutic target.
32 nflammation disease, and therefore represent a potential therapeutic target.
33 sis in disease models, identifying MAP4K4 as a potential therapeutic target.
34 t Gram-negative bacteria and suggest TRIF as a potential therapeutic target.
35 thway for its replication, and they identify a potential therapeutic target.
36 eversible nature of these changes represents a potential therapeutic target.
37 ggesting that acid stress pathways represent a potential therapeutic target.
38 ssed in basal-like TNBC and is considered as a potential therapeutic target.
39 mber of cancers, and it is therefore seen as a potential therapeutic target.
40 vessels, identifying this adaptor protein as a potential therapeutic target.
41 states and has therefore been identified as a potential therapeutic target.
42 esponses following nerve injury in mice, and a potential therapeutic target.
43 phenotype and assessed the Notch1 pathway as a potential therapeutic target.
44 optotic mediator B-cell lymphoma 2 (BCL2) as a potential therapeutic target.
45 al signaling deficits of ASD, and represents a potential therapeutic target.
47 ore, we conclude that TGF-beta may represent a potential therapeutic target against carbofuran-mediat
49 Warburg effect, and indicates that ABHD5 is a potential therapeutic target against mCRPC, the deadly
50 a prognostic marker, and identifies LOXL2 as a potential therapeutic target against tumor progression
53 sibility that WMHs are a core feature of AD, a potential therapeutic target, and a factor that should
55 ey contributor to the pathogenesis of MI and a potential therapeutic target, bolstering the idea that
56 important regulator of cardiac autophagy and a potential therapeutic target, especially in the older
60 is and inflammation suggesting PTEN could be a potential therapeutic target for acute kidney injury.
61 leukaemic state and identify this enzyme as a potential therapeutic target for acute myeloid leukaem
67 and adipogenesis of BMSCs and may represent a potential therapeutic target for age-related bone loss
68 coupled with osteogenesis and may represent a potential therapeutic target for age-related osteoporo
72 ations suggest that the CD82 scaffold may be a potential therapeutic target for attenuating aberrant
73 T-cell apoptosis, making regulation of Erdr1 a potential therapeutic target for autoimmune disease.
74 egulator of T cells and implies that Hrd1 is a potential therapeutic target for autoimmune diseases.
75 data indicate that acetate metabolism may be a potential therapeutic target for BRAF mutant melanoma.
76 maintenance and identify DNMT1-ISL1 axis as a potential therapeutic target for breast cancer treatme
77 ogical functions of RNF126 but also provides a potential therapeutic target for cancer treatment.
78 entify SHP2 as a direct activator of Ras and a potential therapeutic target for cancers driven by a p
79 Together, our results suggest that CKAP4 is a potential therapeutic target for cancers that express
80 tor of cardiac fibrosis, pointing to SOX9 as a potential therapeutic target for cardiac fibrosis.
81 tinic acetylcholine receptor (alpha7-nAChR), a potential therapeutic target for central nervous syste
85 ER proteinopathy in vivo and thus represents a potential therapeutic target for chronic diseases.
88 ation and progression, highlighting AURKA as a potential therapeutic target for combatting hyperactiv
89 ting in a dependence on autophagy, providing a potential therapeutic target for combination therapy w
90 nt to leukaemogenesis and identifies CCL3 as a potential therapeutic target for controlling leukaemic
92 peripheral chemoreflex may be considered as a potential therapeutic target for controlling renovascu
93 the folding efficiency of the mutant and is a potential therapeutic target for correction of the Del
96 ity of neurotransmitter release, emerging as a potential therapeutic target for diseases affecting sy
97 Inhibition of MIF's nuclease activity is a potential therapeutic target for diseases caused by ex
98 of other TLR family members and may provide a potential therapeutic target for diseases characterize
99 sistence of fear extinction and point toward a potential therapeutic target for disorders in which th
100 s study identify sortilin phosphorylation as a potential therapeutic target for ectopic calcification
101 e-activating polypeptide receptor (PAC1R) is a potential therapeutic target for endocrine, metabolic
102 ion and function in patients with EoE and is a potential therapeutic target for EoE and related eosin
103 in alcohol-dependent individuals and provide a potential therapeutic target for further investigation
104 cogenic EGFR signaling and suggest TRIM24 as a potential therapeutic target for GBM that are associat
105 ity-control system in humans, which could be a potential therapeutic target for genetic diseases.
106 astoma progression, suggesting that HSP60 is a potential therapeutic target for glioblastoma treatmen
109 vidence suggests that innate immunity may be a potential therapeutic target for HCV, but it may also
111 her, our results suggest that KDM3A might be a potential therapeutic target for human breast cancer t
113 25, suggesting that this proteinase could be a potential therapeutic target for immune-related diseas
114 (-/low)CD45RA(-)cKIT(-)CD26(+) population as a potential therapeutic target for improved therapy resp
115 circuits in cognition and point to the MD as a potential therapeutic target for improving cognitive d
116 ighlight the NMDA receptor coagonist site as a potential therapeutic target for increased impulsivity
117 sponse to enteric bacterial pathogens and is a potential therapeutic target for infection-induced inf
118 rome, this long non-coding RNA may represent a potential therapeutic target for inflammatory disorder
119 C1/Slug-mediated cancer cell invasion and is a potential therapeutic target for inhibition of cancer
120 inflammation and tumorigenesis, and could be a potential therapeutic target for intestinal malignant
122 tumor infiltration of the lungs and suggests a potential therapeutic target for lung-tropic metastasi
123 , these findings suggest that KSR1 serves as a potential therapeutic target for Merlin-deficient tumo
124 to hepatic insulin resistance in obesity and a potential therapeutic target for metabolic disease.
125 breast cancer metastasis and suggest PLD2 as a potential therapeutic target for metastatic breast can
126 sion, and castration-resistant growth and as a potential therapeutic target for metastatic castration
127 rostate cancer biology and supports Notch as a potential therapeutic target for metastatic prostate c
128 pid metabolism and demonstrate that SRPK2 is a potential therapeutic target for mTORC1-driven metabol
129 d membrane stability and identifies Thbs4 as a potential therapeutic target for muscular dystrophy.
130 uggests that inhibition of intestinal FXR is a potential therapeutic target for NAFLD treatment.
131 ar factor erythroid 2-related factor (Nrf2), a potential therapeutic target for neurodegeneration, co
132 uitin-proteasome system and suggests COP1 as a potential therapeutic target for nonalcoholic fatty li
133 er and identifies the dopaminergic system as a potential therapeutic target for not only infectious d
136 veness to Fgf2, and this integrin represents a potential therapeutic target for pathological conditio
137 diverse mechanisms and highlight the UPR as a potential therapeutic target for patient treatment.
141 identify IRF3 and the type I IFN response as a potential therapeutic target for post-MI cardioprotect
142 during reconsolidation, making this process a potential therapeutic target for posttraumatic stress
145 his study indicates that platelet miR-223 is a potential therapeutic target for prevention of arteria
146 e sterol-accelerated degradation of HMGCR as a potential therapeutic target for prevention of atheros
147 mply that the BMP signaling pathway could be a potential therapeutic target for prevention or inhibit
148 Our data also indicate that CBLB represents a potential therapeutic target for protection from disse
151 ely underlies these phenomena and represents a potential therapeutic target for psychostimulant use d
152 hat miR-101 is an anti-fibrotic microRNA and a potential therapeutic target for pulmonary fibrosis.
156 ignaling in RTT pathogenesis, and identifies a potential therapeutic target for RTT.SIGNIFICANCE STAT
157 e regulation of PV+ IN activity, pointing to a potential therapeutic target for stress-related disord
160 rmoregulation upstream of the SNS, providing a potential therapeutic target for sympathetic hyperacti
162 This finding suggests that Slit2 may be a potential therapeutic target for the effective in vitr
163 flammation and thus highlight cadherin-11 as a potential therapeutic target for the management of obe
164 ting from vHPC to LS in the brain, revealing a potential therapeutic target for the treatment of anor
165 gulator of Rho-kinase activity and therefore a potential therapeutic target for the treatment of asth
166 ata has identified B7-H4 (VTCN1/B7x/B7S1) as a potential therapeutic target for the treatment of canc
167 iverse models of CKD, implicating dynamin as a potential therapeutic target for the treatment of CKD.
168 ) has been gaining considerable attention as a potential therapeutic target for the treatment of comp
169 in FA by impairing HSPC function and may be a potential therapeutic target for the treatment of FA.
170 -kappaB signaling via UNC5A, netrin-1 may be a potential therapeutic target for the treatment of glio
171 ggest that alpha7nAChR expressed by ILC2s is a potential therapeutic target for the treatment of ILC2
172 phoinositide-transfer protein and represents a potential therapeutic target for the treatment of infl
173 omeostasis and identify CX3CR1 signalling as a potential therapeutic target for the treatment of obes
174 the attention of the scientific community as a potential therapeutic target for the treatment of obes
175 of PrP(C) biogenesis and identify FKBP10 as a potential therapeutic target for the treatment of prio
178 ynthesis levels, thus highlighting ERK1/2 as a potential therapeutic target for the treatment of TS.
179 pathway in KRAS-driven cancers, which offers a potential therapeutic target for their eradication.
180 athetic neurotransmitter expressed in NB, as a potential therapeutic target for these tumors by virtu
185 to the loss of motor function and represent a potential therapeutic target for treating symptoms of
186 entiation and uncovers the SKI-SMAD4 axis as a potential therapeutic target for treating TH17-related
187 est that targeting inflammation may serve as a potential therapeutic target for treating these fear-
188 tor required for UM progression and could be a potential therapeutic target for treating UM in the cl
189 in vivo Any step in these processes provides a potential therapeutic target for treatment of secondar
190 g identifies endogenous neural stem cells as a potential therapeutic target for treatment of spinal c
191 ys and suggests that modulation of moesin is a potential therapeutic target for Treg-related immune d
192 identified the prion-like protein doppel as a potential therapeutic target for tumor angiogenesis.
193 nding enables further exploration of GKRP as a potential therapeutic target for type II diabetes and
194 demonstrate that T2R14 in sinonasal cilia is a potential therapeutic target for upper respiratory inf
196 egulator in AAA biology and identify CCN3 as a potential therapeutic target for vascular disease.
197 effects of Tat, glutamate receptors could be a potential therapeutic target for white matter damage i
198 suppressor and uncover the Lin28b pathway as a potential therapeutic target in a molecularly defined
200 complex as a crucial co-activator of AR and a potential therapeutic target in advanced prostate canc
201 ore identified glial muscarinic signaling as a potential therapeutic target in Alexander disease, and
202 The IL-6/follicular helper T cell pathway is a potential therapeutic target in allergic disease.
205 , endocrine, and behavioral responses and is a potential therapeutic target in anxiety and panic diso
207 s a major regulator of Pi homeostasis and as a potential therapeutic target in bone and kidney disord
208 egulate BRCA2 function and point to USP21 as a potential therapeutic target in BRCA2-proficient tumor
210 -621 may serve as a predictive biomarker and a potential therapeutic target in breast cancer treatmen
215 inflammatory T helper 17 (TH17) cells and is a potential therapeutic target in chronic autoimmune and
216 ted by APC/beta-catenin pathway and could be a potential therapeutic target in colon cancers with abe
217 avior and antidepressant response, providing a potential therapeutic target in developing novel antid
219 ted by plasma apolipoproteins and represents a potential therapeutic target in diabetes-associated de
223 lights a role of FOXA1 via IL-8 signaling as a potential therapeutic target in FOXA1-overexpressing E
225 5) is a regulator of cardiac performance and a potential therapeutic target in heart failure in the a
226 ylase 1 (LSD1), which has been considered as a potential therapeutic target in human cancer, has been
229 the liver that should be further explored as a potential therapeutic target in immune-mediated liver
231 B cell IL-10 production and reveal ezrin as a potential therapeutic target in inflammatory diseases.
234 eptor layer and positions IL-33 signaling as a potential therapeutic target in macular degenerative d
235 of t(4;14) MM and further validate MMSET as a potential therapeutic target in MM and other cancers.
238 vitro and in vivo and suggest that RGC-32 is a potential therapeutic target in multiple sclerosis and
239 Macrophages are increasingly recognized as a potential therapeutic target in myocardial fibrosis vi
240 rongly support further research on mGluR5 as a potential therapeutic target in neuropsychiatric disor
243 rpinB2/uPA axis for further investigation as a potential therapeutic target in pancreatic cancer.
244 t and suggests that cxcl8/cxcr1 signaling is a potential therapeutic target in patients undergoing he
245 ght contribute to airway neutrophilia and is a potential therapeutic target in patients with neutroph
246 as an inhibitor of PD-1 function and SHP2 as a potential therapeutic target in patients with XLP.
249 ey further identify beta-cell dysfunction as a potential therapeutic target in people at increased ri
256 gue may comprise a new metabolic factor with a potential therapeutic target in the olfactory bulb (i.
257 The requirement for T-cell help provides a potential therapeutic target in the treatment of antib
258 centrally acting orexigenic hormone that is a potential therapeutic target in the treatment of both
259 ltering the blood-retinal barrier and reveal a potential therapeutic target in the treatment of DR.
260 the bone marrow, and also identify G-CSF as a potential therapeutic target in the treatment of human
261 eration of cartilaginous tissue and serve as a potential therapeutic target in the treatment of OA.
265 ative feedback fashion and suggest PHLDB3 as a potential therapeutic target in various human cancers.
268 ive treatment-induced decrease of asleep BP, a potential therapeutic target requiring ambulatory BP e
271 f human pathologies and has been proposed as a potential therapeutic target therein, we sought to bet
272 differentiation, thereby implicating IRF8 as a potential therapeutic target to affect Th9 responses i
273 ellular matrix in pain, and indicate CD44 as a potential therapeutic target to alleviate inflammatory
274 Our data indicate that PTEN may provide a potential therapeutic target to ameliorate toxic effec
276 he CD40 decoy receptor, sCD40R, may serve as a potential therapeutic target to attenuate renal functi
277 from donors with type 2 diabetes, suggesting a potential therapeutic target to augment insulin produc
278 and produce IL-22, and identify NF-kappaB as a potential therapeutic target to be considered in patho
279 une axis and highlight the gut microbiome as a potential therapeutic target to counteract salt-sensit
281 on, our studies suggest that ASMase could be a potential therapeutic target to ensure the efficient a
282 n after APAP overdose and identified GSK3 as a potential therapeutic target to improve liver regenera
283 ting that the polycystins/TAZ complex may be a potential therapeutic target to increase bone mass.
284 ults identify a novel hepcidin regulator and a potential therapeutic target to increase defective BMP
285 ntifying the phospho-GR/HIF/PELP1 complex as a potential therapeutic target to limit Brk-driven progr
286 sion, our studies indicate that alpha-Syn is a potential therapeutic target to minimize poststroke br
287 ur data identify the alpha5beta1 integrin as a potential therapeutic target to mitigate the severity
288 his critical immune checkpoint and highlight a potential therapeutic target to overcome immune evasio
289 AD(+) salvage pathway in astrocytes could be a potential therapeutic target to prevent astrocyte-medi
290 onstrates that the PDK1/PLCgamma1 complex is a potential therapeutic target to prevent metastasis and
293 uggest that EDN/EDNRB signaling may serve as a potential therapeutic target to promote repigmentation
294 ings highlight the key role of microbiota as a potential therapeutic target to protect brain function
295 cyte-macrophage colony-stimulating factor is a potential therapeutic target to reduce esophageal eosi
296 ulation with the identification of STAMBP as a potential therapeutic target to reduce pro-inflammator
297 inhibition of PERK phosphorylation could be a potential therapeutic target to restore memory deficit
298 Together, our findings suggest RNF31 as a potential therapeutic target to restore p53 function i
299 cancer and neurological disorders, making it a potential therapeutic target to treat human diseases.
300 cell development and suggest this kinase as a potential therapeutic target to treat TH17 cell-driven
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