ライフサイエンスコーパス: a significant increase in

1 erapy versus no downstaging, and this showed a significant increase in 1-year (two studies, RR, 1.11;

2 There was a significant increase in 10-year fracture risk for majo

3 ty (GladioxFidji K2) with 1-pyrroline led to a significant increase in 2AP in both varieties.

4 Our data revealed a significant increase in a poorly-characterized MK prot

5 ations that disrupt this structure result in a significant increase in Abeta production and, in speci

6 However, diet-induced high Hcy resulted in a significant increase in Abeta, tau phosphorylation, ne

7 ure of MDDCs modulates H3 and H4 and induces a significant increase in acetylation at H4K12 (H4K12ac)

8 ut not familiar, taste consumption, there is a significant increase in ACh release in the insular cor

9 sing mutant Ras(Val12) and S100A4, there was a significant increase in activation of the stress kinas

10 s or I/L Exos were added to HUVECs, we found a significant increase in adhesion molecule ICAM-1, chem

11 zole, rifampin, and phenytoin with NOACs had a significant increase in adjusted incidence rates per 1

12 nged Ormdl3(Delta2-3/Delta2-3)/CC10 mice had a significant increase in AHR compared with wild-type mi

13 In patients with SAH, there is a significant increase in albumin oxidation, and albumin

14 Olivine dissolution caused a significant increase in alkalinity of the seawater wit

15 Overall, the speciation results indicated a significant increase in alkane and methane content, an

16 -0.96] for the 12 SQ-HDM group, P = .03) and a significant increase in allergen-specific IgG4.

17 inate stability constants is coincident with a significant increase in An 5f energy degeneracy with t

18 of a blue light-blocking filter in normoxia, a significant increase in angiogenin levels was observed

19 ults in a substantial healthcare burden with a significant increase in annual expenditures the year a

20 In the red cabbage, boiling resulted in a significant increase in antioxidant activity using the

21 A significant increase in antioxidant and ACE inhibitory

22 pared with healthy controls, patients showed a significant increase in apathy on the Initiation subsc

23 Furthermore, there was a significant increase in apoptosis, with a reduction in

24 ered proliferation in the rescue, we observe a significant increase in apoptotic cell density in Foxg

25 d endocytosis in LLC-PK1 cells, resulting in a significant increase in AQP2 membrane accumulation.

26 Concurrently, there is a significant increase in area, diameter, and circularit

27 Insertion of TIPSS was associated with a significant increase in arterial LPS concentrations an

28 The hippocampus shows a significant increase in asymmetry longitudinally and b

29 Furthermore, we observe a significant increase in balanced inversions in radiati

30 adopted an oblate ellipsoid shape and showed a significant increase in beta-strand formation in the f

31 decrease in angiogenin secretion levels and a significant increase in bFGF were observed following l

32 uantitative polymerase chain reaction showed a significant increase in Bifidobacterium spp. in the OI

33 at Salicornia europaea (ecotype RN) exhibits a significant increase in biomass and organic-S accumula

34 ctic dose (10 mg) than with aspirin, without a significant increase in bleeding rates.

35 r risk of death and hospitalization, without a significant increase in bleeding risk.

36 exposure to the canola-rich diet resulted in a significant increase in body weight and impairments in

37 M-implanted bone cylinders, correlating with a significant increase in bone volume by muCT analysis (

38 e not changed by the interventions; however, a significant increase in bone-specific alkaline phospha

39 t movement-onset periods are associated with a significant increase in both low (2-5 Hz)- and high (6

40 There was a significant increase in both nucleus pulposus and annu

41 Following UV-B-induced HSV-1 reactivation, a significant increase in both the number and function o

42 under accelerated conditions (35 degrees C), a significant increase in brown color development was ob

43 Conversely, a significant increase in bulk organic matter accompanie

44 In this study, we observed a significant increase in C1-Ten level in diabetic kidne

45 A significant increase in CAG repeat contractions was al

46 d meet peak demand in specific hours without a significant increase in carbon emissions, although mor

47 ease in amide/carboxyl functional groups and a significant increase in carbonate in the stalk structu

48 hy-guided heart rate optimization results in a significant increase in cardiac output when compared w

49 ost endothelial and haematopoietic cells and a significant increase in cardiomyocyte numbers.

50 We demonstrate a significant increase in CD34(+)CD31(+) hematoendotheli

51 Immunological assessment, revealed a significant increase in CD4CD25forkhead box P3 regulat

52 marker CD68 and Ki-67 showed that there was a significant increase in CD68+Ki-67+ cells in macaques

53 and cell proliferation, respectively, showed a significant increase in cell death in F0 mutants compa

54 At 7d, there was a significant increase in cell surface CD36 (p < 0.05) w

55 ndividuals on antiretroviral therapy induces a significant increase in cell-associated unspliced (CA-

56 Patients with VTE had a significant increase in circulating PMAs and CRP post-

57 We found a significant increase in clinical pregnancy (OR = 1.16,

58 o healthy ECM, infarcted tissues demonstrate a significant increase in collagen content and fiber ali

59 Periurethral tissue staining revealed a significant increase in collagen content and tissue st

60 The primary finding of the study was a significant increase in connectivity in beta and gamma

61 th eyes with PEDF+DHA for 2 weeks, there was a significant increase in corneal epithelial nerve regen

62 rdough and/or chestnut flour addition caused a significant increase in crumb hardness at time 0 while

63 it, multi-target crypt survival curve showed a significant increase in crypt progenitors in irradiate

64 A significant increase in ctDNA at day 15 relative to ba

65 es, 30-day readmissions were associated with a significant increase in cumulative costs.

66 quitoes had a thicker epicuticular layer and a significant increase in cuticular hydrocarbon (CHC) co

67 values over the 43-year record, coupled with a significant increase in d-excess values.

68 highly soluble in sea water, as indicated by a significant increase in dissolved silica across a fjor

69 ffer from nonhuman primate species in having a significant increase in dopaminergic innervation selec

70 with targeted head and neck radiation showed a significant increase in double-stranded breaks (DSB) i

71 There was a significant increase in each of these associated comor

72 We did observe a significant increase in endogenous catalase expression

73 TC-PTP deficiency also resulted in a significant increase in epidermal thickness and hyperp

74 However, there was a significant increase in epilepsy among those older tha

75 ected BECs from subjects with asthma, led to a significant increase in expression of 6199 genes.

76 ence of IRF5, CD11c(-) macrophages displayed a significant increase in expression of the efferocytosi

77 Diffusion tensor imaging analysis revealed a significant increase in FA in bilateral uncinate fasci

78 We observed a significant increase in fatty acid synthase (FASN) exp

79 at CS was likely butyrogenic and resulted in a significant increase in fecal butyrate concentration.

80 he contralateral artery (n=6) did not induce a significant increase in flow velocity.

81 A significant decrease in spawning and a significant increase in follicular atresia in the 30 p

82 One-year after mTOR-i conversion, a significant increase in FOXP3 + Treg cell numbers and

83 Ultrastructure analysis revealed a significant increase in fragmented mitochondria in the

84 A significant increase in free amino groups was observed

85 approaches, based on machine learning, offer a significant increase in functionality, but their clini

86 The prospect of a significant increase in global health-related costs as

87 HER2-overexpressing mammary tumors revealed a significant increase in glutaminolysis, a critical met

88 Mutations mimicking phosphorylation led to a significant increase in GORK activity, whereas mutatio

89 oid withdrawal/avoidance was associated with a significant increase in growth (mean difference in hei

90 A significant increase in H2AK119Ub1 was observed in ASX

91 Compared with controls, Diet-fed mice had a significant increase in Hcy levels, memory and learnin

92 o body ratio in the 30 ppb group, along with a significant increase in head width to body ratio in th

93 Moreover, a significant increase in hippocampal BDNF was detected

94 for kidney tubular toxicity and by observing a significant increase in HO-1 after toxicity using an e

95 we demonstrated that (13)C MRSI could detect a significant increase in HP [1-(13)C]pyruvate-to-lactat

96 ion, H. pylori infection was associated with a significant increase in IL-17C expression in human gas

97 s AMs or PBMCs with IRAK1/4 inhibitor led to a significant increase in IL-1beta mRNA expression both

98 ffect cell viability or survival but induced a significant increase in IL-1beta, TNF-alpha, and IL-6

99 A significant increase in IL18 expression levels was obs

100 bial stewardship program was associated with a significant increase in infectious disease consultatio

101 the community level, it was associated with a significant increase in IR (estimated treatment effect

102 Subtype-specific analyses revealed a significant increase in ischemic heart disease (10-yea

103 increase in surface recycling translated to a significant increase in KCC2 expression in the surface

104 Finally, LRV1 presence was associated with a significant increase in levels of intra-lesional infla

105 controls, individuals with schizophrenia had a significant increase in log-transformed mean serum VEG

106 hese findings are consistent with absence of a significant increase in long-term risk of breast cance

107 e acute phase, treatment was associated with a significant increase in long-term survival.

108 A significant increase in LS values after meal intake wa

109 paB reporter before and after surgery showed a significant increase in luciferase expression, coincid

110 ocking antibody, initiated at day 60, caused a significant increase in markers of microglial activati

111 GP of SM resulted in a significant increase in mean maximum plasma concentrat

112 SMN protein in disease-relevant tissues and a significant increase in median survival time in a dose

113 There was a significant increase in microvesicular steatosis accom

114 Using species-specific primers, we found a significant increase in MMP-9 gene expression in the t

115 This adverse event is associated with a significant increase in morbidity and economic burden,

116 ell line (NG108-15) in vitro, hypoxia caused a significant increase in mRNA and protein for HIF-1alph

117 A significant increase in mucin 2 and SGLT1 expression w

118 A significant increase in myopia among children and teen

119 After the simulated normal condition, only a significant increase in nasal corneal staining (2.9 +/

120 ed blood pressure in AOF females and induced a significant increase in near plasmalemmal p47(phox) an

121 in 37 healthy controls, we further detected a significant increase in network flexibility as a resul

122 In contrast, shawn mutants harbor a significant increase in neurotransmitter release.

123 Concomitantly, a significant increase in neutrophil migration into the

124 Histologically, there was a significant increase in neutrophil tracking in trachea

125 igilin downregulation in target cells led to a significant increase in NK cell activation against sai

126 Also, subjects exposed to HMW agents showed a significant increase in NL levels of C-reactive protei

127 Notably, a significant increase in nonsurvivors compared with sur

128 - 5.56%, P < 0.01), motor cortex showed only a significant increase, in NPY neurons in supragranular

129 Fermentation of jucara pulp resulted in a significant increase in numbers of bifidobacteria afte

130 eated intragastric antigen challenge induced a significant increase in numbers of CD4(+) TH2 cells, w

131 In addition, mice with MAS had a significant increase in numbers of liver CD68(+) macro

132 alanced melting supports the hypothesis that a significant increase in ocean heat influx into ASE sub

133 th mixed type I and II fiber content), while a significant increase in only IMCL content (+48%, p < 0

134 We obtained a significant increase in OPA1 mRNA and protein expressi

135 LPI resulted in angle widening with a significant increase in opening distance (P < .01 for

136 late nucleus V2 density (F, -8.28; P < .05), a significant increase in optic radiation mean diffusivi

137 Ectopic Notch expression causes a significant increase in organ size independently of pr

138 cifically, in Tph1(-/-) mice with arthritis, a significant increase in osteoclast differentiation and

139 A significant increase in oxCCO was found in response to

140 on ascendens stent peritonitis hearts showed a significant increase in oxidation-dependent calcium an

141 nt increase in cellular pigmentation induced a significant increase in PAI signals that are spectrall

142 in two varieties: Hojiblanca and Arbequina, a significant increase in PaO and RCCR activity was foun

143 n transfers of experimental evolution we saw a significant increase in parasite induced host mortalit

144 sampling episodes, only 2 procedures showed a significant increase in particle concentrations over b

145 The TNNT2p.K217del mutation showed a significant increase in passive tension that was not d

146 among these developments that have achieved a significant increase in patient survival in clinical t

147 Only in the lower lobes, a significant increase in PBF after cardiac output adjus

148 both neonatal and adult THS exposure caused a significant increase in percentage of B-cells and sign

149 tive fluid administration is associated with a significant increase in perioperative morbidity in pat

150 Phe (62 +/- 40 mumol/L, P = 0.136), despite a significant increase in Phe intake from GMP-MFs (88 +/

151 The steaming technique resulted in a significant increase in phenolic content in kale (86.1

152 synergistic apoptosis in cancer cells, with a significant increase in phospho(Ser139) histone H2AX (

153 o control, lungs from CS-exposed mice showed a significant increase in PKCalpha activity and Duox-1 e

154 ne, Pinus bungean, with B. xylophilus led to a significant increase in plant hydrogen peroxide (H2O2)

155 increased kidney arginine content as well as a significant increase in plasma creatinine concentratio

156 h analysis of two selected pathways revealed a significant increase in plasma urea level correlating

157 in, as knockdown of eEF-2K expression led to a significant increase in PP2A-A protein synthesis and r

158 function of pH and ionic strength/type, show a significant increase in product stabilities for all ca

159 Embryonic atrazine exposure resulted in a significant increase in progesterone levels in the 3 a

160 e subgranular zone of the hippocampus showed a significant increase in proliferation of neural precur

161 of tumor cells with intact TGF-beta1, showed a significant increase in proliferation rate, as well as

162 PK phosphorylation occurred concomitant with a significant increase in protein phosphatase activity f

163 n alpha7beta1, a laminin-receptor, also show a significant increase in pSTAT3 levels compared with WT

164 demonstrated IBDV induction of autophagy as a significant increase in puncta of LC3(+) autophagosome

165 A bootstrapping analysis confirmed a significant increase in R(2) for the model using bioac

166 We found a significant increase in (R)-(11)C-verapamil distributi

167 Conclusion: We found a significant increase in (R)-(11)C-verapamil distributi

168 Germination caused a significant increase in radical scavenging activity an

169 In adipose tissues, we observed a significant increase in RBM28 mRNA expression in breed

170 blation time (based on quartiles), there was a significant increase in recurrence rates in addition t

171 n observed in these mice was associated with a significant increase in regulatory CD1d(hi)CD5(+) B ce

172 Results show a significant increase in relative fraction of outer-sph

173 essure gradient relation was consistent with a significant increase in relative stenosis severity (k

174 Rats exhibited a significant increase in responding for sufentanil when

175 Patients with BARC (2, 3, or 4) bleeding had a significant increase in risk of death versus patients

176 tors for stroke, PPI use was associated with a significant increase in risk of ischemic stroke (hazar

177 CRF injection caused a significant increase in salivary cortisol, which laste

178 cts on cardiac hypertrophy and fibrosis, but a significant increase in scar thickness.

179 s of toxicities, and was not associated with a significant increase in second malignancies with this

180 Gonococcal infection induced a significant increase in secreted MMP-9 and an accumula

181 sional gas chromatography (GC x GC) provides a significant increase in selectivity and peak capacity

182 d to nucleic acid sensing, this accounts for a significant increase in sensitivity (that is, lower li

183 Specifically, the sensors show a significant increase in sensitivity toward CO when neg

184 We found a significant increase in serum IL-10 and IL-8 levels af

185 se in muscle mass, which was associated with a significant increase in silent mating type information

186 In vivo, CLP led to a significant increase in splenic cfB expression that co

187 participants in the exercise group displayed a significant increase in striatal D2/D3 BPND, whereas t

188 There was a significant increase in suicide-specific mortality (SM

189 and protecting mitochondria, which leads to a significant increase in survival in SOD1(G93A) mice.

190 o M1/M2 gene expression were associated with a significant increase in survival of neurons, microglia

191 However, a significant increase in synaptophysin immunolabeled pu

192 dynamin proline-rich domain that account for a significant increase in syndapin binding affinity comp

193 patients with non-ITDM, those with ITDM had a significant increase in target vessel failure (42 [5.6

194 Improved survival is associated with a significant increase in telomere length in peripheral

195 M6CA represents a significant increase in terms of analytical performanc

196 Reduced bodyweight gain and a significant increase in the abosamal pH was observed i

197 e higher peptide amount injected, leading to a significant increase in the absorbed dose to the tumor

198 Methane starvation is associated with a significant increase in the abundance of gene transcri

199 ssed ASYN interacted with dynein and induced a significant increase in the activated levels of small

200 Concomitant to this a significant increase in the activation of TAK1-mediate

201 gs of SE2(-/-) mice was also associated with a significant increase in the activation of thrombin, a

202 f neurofeedback training were sufficient for a significant increase in the alpha power to occur.

203 This study confirms that LPI results in a significant increase in the angle width, ACD, and ACA

204 Prior work showed a significant increase in the association between obesit

205 We observed a significant increase in the CD59 expression on the sur

206 mTBI resulted in a significant increase in the cell swelling within 30 mi

207 a delay in grape technological maturity and a significant increase in the concentration of several b

208 e also confirmed by SE-HPLC technique, where a significant increase in the content of proteins and pe

209 aphy in both AMS and non-AMS subjects showed a significant increase in the cross-sectional areas of t

210 However, it did result in a significant increase in the delay to lever pressing.

211 f multiplex molecular diagnostics has led to a significant increase in the detection of respiratory v

212 g the concentration up to 30 mg L(-1) showed a significant increase in the dissolution of CO2 bubbles

213 When the method is applied to mouse retinae a significant increase in the DOPAC/DA ratio is observed

214 Minocycline also caused a significant increase in the expression of anti-inflamm

215 tivity before VSV administration resulted in a significant increase in the expression of CCL2 and dec

216 On a molecular level, we observed a significant increase in the expression of HOXD10, whic

217 vels, hepatic Foxo1/3/4 deficiency triggered a significant increase in the expression of inflammatory

218 We observed a significant increase in the expression of the gene enc

219 analysis of dyW-/- E17.5 muscles identified a significant increase in the expression of the JAK-STAT

220 ell electrophysiological recordings detected a significant increase in the frequencies of spontaneous

221 vates the cAMP-PKA-dependent pathway, caused a significant increase in the frequency of active ICAM-4

222 of the tubulin acetyltransferase TAT1 led to a significant increase in the frequency of microtubule b

223 This alteration translated into a significant increase in the frequency of Tregs and red

224 umor progression was also found to result in a significant increase in the hydrodynamic size of facto

225 8) results in loss of calmodulin binding and a significant increase in the in vitro ubiquitylation ac

226 diate anti-lymphoma activity without causing a significant increase in the incidence of GVHD, we stud

227 eased rapidly in the past 4 decades, without a significant increase in the incidence of rare diseases

228 Live tutoring resulted in not only a significant increase in the influence of experience on

229 There was a significant increase in the kinetic uptake coefficient

230 phosphorylase (PNPase) binding domain led to a significant increase in the level of PNPase synthesize

231 neutrophil migration into the peritoneum and a significant increase in the levels of CCL4 in peritone

232 (day 7: mean reduction, 62%; P = .029), with a significant increase in the mean lumen vessel area (da

233 We observed a significant increase in the mRNA level of the spo0B ge

234 Here, we report a significant increase in the mtDNA mutation frequency i

235 of circulating nanoparticles, would lead to a significant increase in the nanoparticle delivery effi

236 Both metformin and pioglitazone resulted in a significant increase in the number and regulatory func

237 rate that endothelial deletion of App causes a significant increase in the number of BrdU label-retai

238 The exacerbated disease was associated with a significant increase in the number of CNS-infiltrating

239 the one hand, we demonstrated that there was a significant increase in the number of E. coli at the s

240 In the past decade, there has been a significant increase in the number of epidemiological

241 the films to 1,2-dichloroethane vapor led to a significant increase in the number of nuleation sites,

242 7 patients with sCJD in this study there was a significant increase in the number of regions demonstr

243 The recent decades have witnessed a significant increase in the number of these extreme ra

244 le influence on antibacterial activity, with a significant increase in the observed inhibitory effect

245 received CMV-ATCT-DC vaccination experienced a significant increase in the overall frequencies of IFN

246 There was a significant increase in the overall incidence of anaph

247 uring immediate target processing, there was a significant increase in the parietal P3 amplitude with

248 e response evident in pH 5.0, giving rise to a significant increase in the peak current of DA.

249 The T2D module led to a significant increase in the percentage of patients und

250 induced antiviral states in cells results in a significant increase in the percentage of robust infec

251 first time, we demonstrated that OIT induced a significant increase in the peripheral blood iNKT, as

252 With pro-CD treatment, there was a significant increase in the phosphorylation of the dow

253 ment some additives decomposed and there was a significant increase in the polyolefin oligomeric satu

254 in arrestin 2 knock-outs (KOs), we observed a significant increase in the potency of SNC80 to inhibi

255 tomosynthesis at year 3, P = .2), there was a significant increase in the PPV3 (29.6% vs 50%, respec

256 ase activity in the absence of Ca(2+) showed a significant increase in the presence of these Tms, ind

257 Ageing in humans is associated with a significant increase in the prevalence of cardiovascul

258 There has been a significant increase in the prevalence of low VA, with

259 There is a significant increase in the probability of void format

260 There was a significant increase in the proportion of patients mee

261 illation and at risk for stroke, resulted in a significant increase in the proportion of patients tre

262 Intra-arterial treatment did not cause a significant increase in the proportion of patients wit

263 There was a significant increase in the proportion of PCIs at cent

264 final assessment categories over time, with a significant increase in the proportion of studies clas

265 Additionally, we found a significant increase in the quantity of peripherally i

266 The use of CCDSSs was associated with a significant increase in the rate of appropriate orderi

267 The results obtained from the model showed a significant increase in the rate of sample laboratory

268 tments on the antioxidant capacity; however, a significant increase in the reducing potential was det

269 Patients with ITDM had a significant increase in the risk of cardiovascular eve

270 miscarriage, although it is associated with a significant increase in the risk of second trimester m

271 This results in a significant increase in the scanning speed from the mi

272 We observed a significant increase in the secretion of TGF-beta1 lig

273 Acute B19V infection caused a significant increase in the serum concentration of CXC

274 enous fluid boluses were not associated with a significant increase in the sonographic measure of the

275 Accordingly, a significant increase in the specific activity of Vps34

276 MIL-101(Cr)/GO in methanol exhibited a significant increase in the thermal conductivity (by a

277 reducing the DPM mass emissions, but lead to a significant increase in the total particle counts due

278 atenin is dramatically increased, leading to a significant increase in the transcription of beta-cate

279 At follow-up, there was a significant increase in the use of ezetimibe, drug com

280 chical logistic regression models, there was a significant increase in the use of moderate-intensity

281 I public reports in 2006 was associated with a significant increase in the use of PCI for cardiogenic

282 ned cross-sections, both approaches revealed a significant increase in the variability of tissue orga

283 This led to a significant increase in the very-long-chain fatty acid

284 CCS deployment can lead to a significant increase in the water use of hybrid coolin

285 Arrayan berries show a significant increase in their antioxidant capacity fro

286 we found that HT mice after seizures showed a significant increase in total activity and total dista

287 witching to dual therapy was associated with a significant increase in total, low-density lipoprotein

288 Furthermore, biochar addition led to a significant increase in transcript production among mi

289 ingly, immediately after treatment there was a significant increase in transforming growth factor bet

290 andwidth of the input illumination, yielding a significant increase in transport efficiency relative

291 ession or devoid of TGF-beta1 in vivo showed a significant increase in tumor growth kinetics in both

292 erozygosity on BRCA2 loss is demonstrated by a significant increase in tumorigenesis in Brca2(cko/cko

293 entiation of brown adipocytes as revealed by a significant increase in UCP1 mRNA (p = 0.03) and lipol

294 ed significant tumor-specific cell death and a significant increase in unspliced pre-mRNAs.

295 The C3 species showed a significant increase in unthreshed grain yield of 50%

296 We observed a significant increase in urinary microbial diversity in

297 ndividuals of European descent, PGS provided a significant increase in variation in QT interval expla

298 eriod (from 18 to 19 years of age) there was a significant increase in VF compared with the reference

299 endent of this heart rate change, CCh caused a significant increase in VFT (control 1.5 +/- 0.3 mA, C

300 at are controlled by MOF, as correlated with a significant increase in yH2AX nuclear foci in Mof-defi