ライフサイエンスコーパス: aberrantly

1 east, lung, and colon cancers expressed GARP aberrantly.

2 It is likely that the aberrantly accelerated MMP-9 proteolysis during neurogen

3 Rad18-deficient fibroblasts aberrantly accumulated DNA damage markers after DMBA tre

4 Nrf2 is aberrantly accumulated in many types of cancer, and its

5 uggesting that pharmacological inhibition of aberrantly accumulated Rock2 may be a suitable therapeut

6 g, the CRAF fusions QKI-RAF1 and SRGAP3-RAF1 aberrantly activate both the MAPK and phosphoinositide-3

7 ating autoimmune disease is the potential to aberrantly activate CD4(+) T cells due to cross-recognit

8 oncogenic drivers identified in this cohort aberrantly activate MAPK signaling, including the 2 soma

9 ations within noncoding genomic regions that aberrantly activate oncogenes have remained poorly chara

10 monly associated with BRAF gene fusions that aberrantly activate the mitogen-activated protein kinase

11 ve implications for B-cell malignancies that aberrantly activate this pathway.

12 These observations suggest that aberrantly activated "AKI" pathways may drive pathogenes

13 e for branched-chain amino acids (BCAAs), is aberrantly activated and functionally required for chron

14 Developmental signals are aberrantly activated and stem cell functions are disrupt

15 Therefore, our study revealed that aberrantly activated AREG-EGFR signaling is required for

16 s also identified miRNA/gene-target networks aberrantly activated at the initial stage of hepatocarci

17 ment of new strategies to selectively target aberrantly activated B cells and restore normal B-cell h

18 Simultaneous inhibition of aberrantly activated BRAF and knockdown of miR-3151 pote

19 ositol-3 kinase (PI3K)/Akt pathway, which is aberrantly activated in >50% of carcinomas, inhibits apo

20 The hedgehog (Hh) signaling pathway is aberrantly activated in a majority of basal cell carcino

21 The Ras proteins are aberrantly activated in a wide range of human cancers, o

22 nd adaptive immune responses, is known to be aberrantly activated in a wide variety of cancers.

23 Hedgehog pathway signalling is aberrantly activated in around 95% of tumours.

24 e growth factor-1 (IGF-1) signaling axes are aberrantly activated in both primary PCa and bone metast

25 ormation, suggesting that the Wnt pathway is aberrantly activated in breast cancer mammospheres.

26 as a target for APA, a regulatory mechanism aberrantly activated in cancer cells, and provides novel

27 esses during metazoan development and can be aberrantly activated in cancer.

28 ntral regulator of cell growth that is often aberrantly activated in cancer.

29 rowth, proliferation, and metabolism that is aberrantly activated in cancers and certain cancer-assoc

30 stinal stem cell (ISC) proliferation, and is aberrantly activated in colorectal cancer.

31 nd a crucial signalling hub in many pathways aberrantly activated in disease.

32 pment and tissue regeneration, thought to be aberrantly activated in epithelial-derived cancer and ha

33 rols potassium balance in health and becomes aberrantly activated in FHHt.

34 insulin-like growth factor (IGF) pathway is aberrantly activated in HCC by IGF2 overexpression.

35 ate that the RANK and NF-kappaB pathways are aberrantly activated in luminal progenitor cells residen

36 ffectors, thus controlling a pathway that is aberrantly activated in medulloblastoma.

37 The hedgehog signaling pathway is aberrantly activated in most BCC tumors providing an att

38 TET1ALT is aberrantly activated in multiple cancer types including

39 entify endothelin 2 (Edn2) as an NFIB target aberrantly activated in NFIB-deficient hair follicle ste

40 ll-specific protein-tyrosine kinase (LCK) as aberrantly activated in PPR patients.

41 We found that Wnt signalling is aberrantly activated in regeneration-deficient tissues.

42 Target of Rapamycin (mTOR) pathway is often aberrantly activated in rhabdomyosarcoma (RMS) and repre

43 ream of and downstream from her-1 to prevent aberrantly activated male developmental programs in herm

44 The failure of targeted therapies against aberrantly activated oncogenic signaling, such as that o

45 at the efficiency of therapies targeting the aberrantly activated PI3K/PDK1/Akt pathway might be incr

46 ous recombination in A549 cells that express aberrantly activated STAT3.

47 hanism for early dissemination in which Her2 aberrantly activates a program similar to mammary ductal

48 e transport, while phosphomimetic JIP1-S421D aberrantly activates anterograde transport.

49 nhanced regeneration of injured DRs, without aberrantly activating SCs and axons in intact nerves.

50 By aberrantly activating the RAF-MEK-ERK signaling pathway,

51 We previously reported that in cancer, aberrantly active LINE-1 promoters can drive transcripti

52 Treatment of U251MG cells that harbor aberrantly active signal transducer and activator of tra

53 human lung tumor xenografts (A549) harboring aberrantly active STAT3.

54 findings suggest that the mutant LRSAM1 may aberrantly affect the formation of transcription machine

55 The accumulation of aberrantly aggregated MAPT (microtubule-associated prote

56 We showed that exon alpha in MEF2C was aberrantly alternatively spliced in RMS cells, with the

57 These aberrantly amplified DEREs deregulated target gene expre

58 Here, we show that reactive astrocytes aberrantly and abundantly produce the inhibitory gliotra

59 ment of a B cell repertoire that is not only aberrantly autoreactive but also hyperresponsive to anti

60 In patient tissue, desmosomal proteins were aberrantly clustered and patient IgG colocalized with ma

61 cal imaging revealed that neoarterioles were aberrantly covered by smooth muscle cells, with increase

62 HDAC8 aberrantly deacetylates p53 and promotes LSC transformat

63 ssor protein promyelocytic leukemia (PML) is aberrantly degraded in multiple types of human cancers t

64 histone modification H4-acetylation, whereas aberrantly depleted with repressive histone modification

65 rowth, TGF-beta-responding progenies invade, aberrantly differentiate, and affect gene expression.

66 creatic progenitor; (3) immunogenic; and (4) aberrantly differentiated endocrine exocrine (ADEX) that

67 physiologically maintained, endogenous p220 aberrantly directs at least one DNA repair protein, RAD5

68 ns of MAP1B, another brain-enriched MAP, was aberrantly distributed in the soma and dendrites of muta

69 ng that normal epithelia may engulf and kill aberrantly dividing neighbours.

70 ver, the expressions of FGF21 receptors were aberrantly down-regulated in HFD rats.

71 While the expression of c-MYC can be aberrantly driven by genetic abnormalities, such as chro

72 stigated the functional consequences of such aberrantly elevated acetylation of the nuclear receptor

73 activation and stability as a consequence of aberrantly elevated CK2 provoked by p53 ablation and irr

74 ng the TGFbeta superfamily, all of which are aberrantly elevated in DND1-deficient PGCs.

75 port that the expression of the INTU gene is aberrantly elevated in human basal cell carcinoma (BCC),

76 ession of the immediate-early gene c-fos was aberrantly elevated in the Bdnf(+/-)dorsal striatum, and

77 -dependent phosphorylation of GluR1 was also aberrantly enhanced in the striatum of young and aged Lr

78 owever, inhibition of JNK signaling leads to aberrantly enhanced localization of E-cadherin at oocyte

79 ecific mutants (sifA and sdhA, respectively) aberrantly enter the cytosol.

80 ved destabilized tropomyosin positioning and aberrantly exposed myosin-binding sites under low Ca2+ c

81 The mutant proerythroblasts also aberrantly express genes of the myeloid lineage as well

82 , Rb1-mutant tumors are undifferentiated and aberrantly express homeobox gene clusters.

83 iffuse large B-cell lymphomas (DLBCLs) often aberrantly express oncogenes that generally contain comp

84 that contained Car4(-/-) hematopoietic cells aberrantly expressed a series of genes enriched in biolo

85 However, aberrantly expressed ALK is involved in the pathogenesis

86 sually expressed in a tumor-specific manner, aberrantly expressed antigens are often shared between c

87 We found that RSPO3 is aberrantly expressed at high levels in approximately hal

88 Emerging NOD breakthrough cells aberrantly expressed both stem cell-associated proto-onc

89 in primary BL suggests that LEF1 is not only aberrantly expressed but also transcriptionally active.

90 lls remained adjacent to the neural tube and aberrantly expressed E-cadherin while lacking N-cadherin

91 ave applied small RNA sequencing to identify aberrantly expressed exosomal miRNAs as candidates for d

92 We find a median of one aberrantly expressed gene, five aberrant splicing events

93 Thousands of aberrantly expressed genes in lesional skin normalized w

94 interaction networks of proteins encoded by aberrantly expressed genes over signaling pathways assoc

95 The current goals were to identify aberrantly expressed genes that contribute to impaired f

96 Instead, a consistent feature of the aberrantly expressed genes was a reduced magnitude of ex

97 the maintenance of ES cell self-renewal, is aberrantly expressed in 47.7% of primary human endometri

98 e oncogenic transcription factor TAL1/SCL is aberrantly expressed in 60% of cases of human T cell acu

99 ated human ether-a-go-go (hEAG1) channel are aberrantly expressed in a large proportion of human canc

100 or tyrosine kinases, was identified as being aberrantly expressed in a significant proportion of HCC;

101 P78 serves as a master UPR regulator that is aberrantly expressed in a variety of cancers, including

102 1-C-terminal subunit (MUC1-C) oncoprotein is aberrantly expressed in AML blasts and stem cells; howev

103 IP also inhibits syndecan-2 (SDC2), which is aberrantly expressed in breast cancer, via downregulatio

104 Rac-guanine nucleotide exchange factor (GEF) aberrantly expressed in breast cancer.

105 They are often aberrantly expressed in cancer and have been implicated

106 a core component of the cell cycle, is often aberrantly expressed in cancer where it may impact cell

107 -transcriptional regulation of mRNAs and are aberrantly expressed in cancer with important roles in t

108 osome organization, is frequently mutated or aberrantly expressed in cancer.

109 MMACHC, a downstream target of HCFC1 that is aberrantly expressed in cblX.

110 on, therefore we hypothesized that proteases aberrantly expressed in diabetic nephropathy (DN) may be

111 Many bromodomain-containing proteins are aberrantly expressed in diseases, as best studied in can

112 c MUC1-C transmembrane protein is, like MYC, aberrantly expressed in diverse human cancers.

113 many genes implicated in Wnt signaling were aberrantly expressed in Fancc(-/-) B cells.

114 tion of a stem cell regulatory gene which is aberrantly expressed in glioma and associated with patie

115 trogen-related receptor alpha (ERRalpha) are aberrantly expressed in human colon cell lines and tumor

116 SALL4 is aberrantly expressed in human myelodysplastic syndromes

117 CXCR4 is aberrantly expressed in immune-mediated diseases and its

118 miRNAs (microRNAs) are frequently and aberrantly expressed in many cancers.

119 iptional coactivator of beta-catenin that is aberrantly expressed in many human cancers but is of low

120 As such, MCPH1 is aberrantly expressed in many malignancies, including bre

121 s an oncogenic transmembrane protein that is aberrantly expressed in MM cell lines and primary tumor

122 The protein Vav1 is aberrantly expressed in more than half of pancreatic can

123 1 C-terminal subunit (MUC1-C) oncoprotein is aberrantly expressed in most MM cells, and targeting MUC

124 factor nuclear factor erythroid 2 (NF-E2) is aberrantly expressed in MPN patients.

125 , we observed Wilms tumor only when Lin28 is aberrantly expressed in multiple derivatives of the inte

126 lly expressed in immune cells but also found aberrantly expressed in multiple human carcinomas.

127 Additionally, Mer is aberrantly expressed in numerous other malignancies sugg

128 Although MUC13, a transmembrane mucin, is aberrantly expressed in pancreatic ductal adenocarcinoma

129 Tissue factor (TF) is aberrantly expressed in solid cancers and is thought to

130 apoptosis (Tweak) and its receptor Fn14 are aberrantly expressed in spinal astrocytes and skeletal m

131 th groups, whereas the CRABP2 and FABP5 were aberrantly expressed in the tumor cells of the sebaceous

132 Importantly, these GC-regulated genes are aberrantly expressed in TNBC patients and are associated

133 MUC5AC is a secretory mucin aberrantly expressed in various cancers.

134 Our study identifies a set of aberrantly expressed lincRNAs in breast cancer.

135 tly, our method can be applied to prioritize aberrantly expressed lncRNAs for functional validation i

136 We report, for the first time, aberrantly expressed lncRNAs in MDS and further prioriti

137 an urgent need to identify and characterize aberrantly expressed miRNAs in HCC.

138 as been put into identifying and cataloguing aberrantly expressed miRNAs in leukaemia, very little is

139 Previous studies suggest that aberrantly expressed Muc4 can influence the adhesiveness

140 by activation of LGR4, an R-spondin receptor aberrantly expressed on MM cells.

141 Both of these truncated glycans are aberrantly expressed on the MUC1 glycoprotein in a spect

142 cs and network analyses--that in human LSCs, aberrantly expressed proteins, in both imatinib-responde

143 The identification of mutated and aberrantly expressed self-tumor antigens has historicall

144 kers for pathologies in which miR levels are aberrantly expressed, such as cancer.

145 genes, including extra-embryonic genes, are aberrantly expressed.

146 diploid human colonic epithelial cells that aberrantly expresses the epidermal growth factor recepto

147 al transcription termination factor MOC1 and aberrantly expresses the mitochondrial genome, resulting

148 ctin positioning to a myosin-blocking state, aberrantly favoring muscle relaxation, thus mimicking th

149 cells both express receptors that recognize aberrantly folded human leucocyte antigen.

150 An aberrantly folded protein (PrP(Sc)) is the main componen

151 To ensure that aberrantly folded proteins are cleared from the endoplas

152 al and synaptic loss, deposition in brain of aberrantly folded proteins, and impairment of spatial an

153 It is not surprising that aberrantly folded RNA structures contribute to disease.

154 embryo, as well as poorly looped hearts with aberrantly formed right ventricles and defective atriove

155 racterized by diverse symptoms indicative of aberrantly functioning immunity.

156 he absence of transport to the Golgi, Rh1 is aberrantly glycosylated and is mislocalized.

157 T cells directed against Tn-MUC1 and present aberrantly glycosylated antigens as a novel class of tar

158 The origin of the aberrantly glycosylated IgG was determined by measuring

159 This work defines a critical role for aberrantly glycosylated MUC1 and identifies an activatin

160 Immunity in which they describe targeting of aberrantly glycosylated tumor-associated cell membrane m

161 In cortical neurons lacking the gamma-Pcdhs, aberrantly high activity of FAK and of PKC disrupts dend

162 Surprisingly, psrA(-) cells displayed aberrantly high basal and poststimulus phosphorylation o

163 he loss of wdb/PP2A function cooperates with aberrantly high Cyclin E protein levels, allowing cells

164 Aberrantly high FOXP1 expression is frequently observed

165 al center B-cell (GCB) DLBCL cell lines with aberrantly high FOXP1 levels; S1PR2 expression is furthe

166 Growth factor receptor levels are aberrantly high in diverse cancers, driving the prolifer

167 eins Crumbs and phospho-Moesin accumulate to aberrantly high levels in braided terminal cells.

168 cinoma, and neoplasia in mouse prostate with aberrantly high levels of Ube2e1 in the cytoplasm.

169 ts in recently experienced stimuli acquiring aberrantly high salience.

170 The aberrantly high Smad3 phosphorylation levels and SBE act

171 ngosine-1-phosphate lung levels, which, when aberrantly high, contribute to lung fibrosis, maladaptiv

172 led that the WNT pathway antagonist FRZB was aberrantly hypermethylated and underexpressed in MDS str

173 aled that the methyltransferase, DNMT3A, was aberrantly hypermethylated and underexpressed, but not m

174 yonic developmental programs are reactivated aberrantly in adult organs to drive repair and regenerat

175 secreted, oncogenic mucin that is expressed aberrantly in AML blasts, but its potential uses to targ

176 selectively in the mammalian brain but also aberrantly in cancer cells.

177 s a novel oncoprotein, gankyrin is expressed aberrantly in cancers from several different sites and h

178 e found that Ras/ERK activities are elevated aberrantly in p120RasGAP-deficient neurons.

179 naling in vascular disease, is overexpressed aberrantly in some breast cancers.

180 affic to the plasma membrane and accumulates aberrantly in the cytoplasm in RalA disrupted embryos.

181 of cyclin B1, a mitotic protein accumulated aberrantly in the damaged brain areas of Alzheimer's dis

182 However, the GFP expression was aberrantly increased in the HSCs and was associated with

183 Aberrantly increased NF-kappaB O-GlcNAcylation has been

184 Aberrantly increasing Arm activity in immature INPs furt

185 ed to dysregulation of DISC1-PDE4 complexes, aberrantly increasing the activity of PDE4.

186 In the absence of T-bet, IFN-gamma aberrantly induced a type I IFN transcriptomic program.

187 mulation and immunoglobulin A production and aberrantly induced the transcription factor Foxo1.

188 cells regardless of whether this pathway is aberrantly induced, making them ideal candidates for che

189 F10 constitutively activate transcription by aberrantly inducing both AEP-dependent transcriptional a

190 une cells associated with acute inflammation aberrantly infiltrated into reproductive organs of pregn

191 inding proteins involved in translation that aberrantly interact with the CGG-containing RNA; however

192 utant, but not wild-type, GlyRS was shown to aberrantly interact with the Trk receptors and cause mis

193 initial self-association, and it cross-links aberrantly into denser, less porous hydrogels with reduc

194 e to avoid its normal target area and branch aberrantly, leading to improper cellular positioning.

195 a subset of acute myeloid leukaemias, PRH is aberrantly localised and its activity is downregulated.

196 hough components of the ciliary rootlet were aberrantly localized away from the base of the cilium.

197 ning OM lipid asymmetry via the transport of aberrantly localized phospholipids (PLs) from the OM to

198 m produced through premature polyadenylation aberrantly localizes to the plasma membrane and/or in cy

199 l experiments demonstrated that voltage from aberrantly located preretinal neovascular complexes is t

200 , monomeric EGFP, tagRFPt, and mApple) cause aberrantly long motor run lengths.

201 Moreover, aberrantly long telomeres were observed in the double-mu

202 sulting in increased telomerase activity and aberrantly long telomeres.

203 SIRT1 function is aberrantly low in obesity, so understanding the underlyi

204 We found that aberrantly methylated CpGs are enriched in regulatory re

205 e" has revealed that virtually all CRCs have aberrantly methylated genes and altered miRNA expression

206 studies (EWAS) have successfully identified aberrantly methylated genes in many diseases and disorde

207 In contrast, aberrantly methylated genes in PMF were involved in infl

208 ovel epigenetic clusters of DLBCLs and their aberrantly methylated genes, molecular associations, and

209 stone related epigenetic marks and are often aberrantly methylated in breast cancer.

210 of the dual-specificity phosphatase DUSP4 is aberrantly methylated in nodal and extranodal DLBCL, irr

211 er apical E-cadherin and F-actin levels, and aberrantly mobile Rho-kinase structures.

212 al-epithelial paracrine signaling, which can aberrantly modulate cellular proliferation and tumorigen

213 king of proteins and RNAs, some of which are aberrantly modulated in BCR-ABL1(+) leukemias.

214 1 mutants, abnormal gene expression leads to aberrantly motorized corticocortical and corticofugal ou

215 r amino acid 807 causes the C region to form aberrantly multimeric and aggregated complexes with an u

216 marily from studies with cultured cell lines aberrantly or ectopically expressing PRLs.

217 Aberrantly or excessively expressed proteins in the endo

218 resynaptic active zone protein bruchpilot is aberrantly organized in FUS-ALS larvae.

219 Second, ROS-low LSCs aberrantly overexpress BCL-2.

220 epidermal growth factor receptor (HER) 3 is aberrantly overexpressed and correlates with poor progno

221 However, in many cancers, cyclin E1 is aberrantly overexpressed and this molecular phenotype co

222 pressed during mammary gland development and aberrantly overexpressed in aggressive 'basal' subtype b

223 transmembrane mucin 1 (MUC1) oncoprotein is aberrantly overexpressed in breast cancer cells and asso

224 The oncogenic MUC1-C protein is aberrantly overexpressed in diverse carcinomas; however,

225 meric protein formed by two subunits that is aberrantly overexpressed in human breast cancer and othe

226 The mucin 1 (MUC1) heterodimeric protein is aberrantly overexpressed in human carcinoma cells.

227 tocellular carcinoma) receptor B4 (EPHB4) is aberrantly overexpressed in human colon tumor cell lines

228 he spindle assembly checkpoint signal and is aberrantly overexpressed in many human cancers.

229 MUC1) is a heterodimeric oncoprotein that is aberrantly overexpressed in most TNBC.

230 found that 24 PCD stage-specific miRNAs are aberrantly overexpressed in multiple myeloma (MM) tumor

231 Mucin 1 (MUC1) is aberrantly overexpressed in NSCLC, activates the nuclear

232 Although EGFL7 is aberrantly overexpressed in solid tumors, its role in le

233 We found that EZH2 is aberrantly overexpressed in the majority of natural kill

234 In these mice, CD14 was aberrantly overexpressed on granulocytes in a cell-auton

235 growth factor and anchorage stimulation, is aberrantly overexpressed or activated in most solid tumo

236 eptor tyrosine kinase has been identified as aberrantly overexpressed, potentially having activating

237 observed cerebral vessels were tortuous and aberrantly patterned at embryonic (E) day 10.5 in podopl

238 phosphorylation was increased, but STAT5 was aberrantly phosphorylated in response to IL-2 stimulatio

239 mmon drug used for restoring the function of aberrantly phosphorylated proteins in lung cancer.

240 Phosphopeptides derived from aberrantly phosphorylated proteins that are presented on

241 investigate the mechanisms maintaining STAT3 aberrantly phosphorylated using transcriptional protein

242 t at 8 h post IR, BRCA1 foci are smaller and aberrantly positioned compared to control cells.

243 e oncogenic U2AF35(S34F) mutant and identify aberrantly processed pre-mRNAs by deep sequencing.

244 d and more homogenous, rostral layer Va SCPN aberrantly project to the spinal cord, and many dual-pro

245 PD0325901 treatment reduced aberrantly proliferating cells in neurofibroma and MPNST

246 ation at 48 hours in KO, which, however, are aberrantly prolonged up to 72 hours.

247 in fascicular reorientation, resulting in an aberrantly proximal skeletal-smooth muscle boundary.

248 fundamental role during embryogenesis and is aberrantly reactivated during progression and metastasiz

249 that is primary restricted to germ cells and aberrantly reactivated in various cancers.

250 tumor suppressor stabilizes beta-catenin and aberrantly reactivates Wnt/beta-catenin target genes in

251 Aberrantly rearranged immunoglobulin (Ig) alleles are fr

252 MLL-AF9 and other MLL fusion proteins aberrantly recruit epigenetic regulatory proteins, inclu

253 These results were consistent with aberrantly reduced stromal cell proliferation and comple

254 A growing body of literature has implicated aberrantly regulated activity of TG2 in the pathogenesis

255 or invasion into the smooth muscle layer and aberrantly regulated aggressive signatures (Smad4 and Sp

256 This finding supports the view that aberrantly regulated gene expression networks in multipl

257 Herein, we discuss the influence of aberrantly regulated histone deacetylases (HDACs) in tum

258 nder an epigenetic control mechanism that is aberrantly regulated in infertility patients.

259 WNT pathways are aberrantly regulated in multiple tumor types (albeit in

260 Accumulating evidence on aberrantly regulated ncRNAs, including short microRNAs,

261 unity following pathogen challenge, but when aberrantly regulated, drive pathogenic antibody formatio

262 or alpha (PDGFRalpha) signaling, which, when aberrantly regulated, is associated with developmental d

263 egeneration but may also cause fibrosis when aberrantly regulated.

264 motes crypt hyperplasia and tumorigenesis by aberrantly regulating Wnt/beta-catenin signaling.

265 We found that PRC2 target genes were aberrantly repressed in WT1mut AML, and that expression

266 Pdx1(-/-) microlumen diameters expand aberrantly, resulting in failure of epithelial tubulogen

267 Here, we discuss how aberrantly S-nitrosylated proteins (SNO-proteins) play a

268 Growth differentiation factor 15 (GDF15) is aberrantly secreted by bone marrow stromal cells (BMSCs)

269 multiple nuclei, and a wide distribution of aberrantly segregating chromosomes.

270 The aberrantly shaped cores in ALLINI-treated particles can

271 The defective dental mesenchyme then aberrantly signals to the dental epithelia, which prompt

272 SS18-SSX is able to directly recruit PRC2 to aberrantly silence target genes.

273 continuity, form when elimination of single, aberrantly specified cells fails and cells proliferate t

274 Juxtaposition of wild-type and aberrantly specified cells induces enrichment of actomyo

275 The aberrantly spliced adgra2 transcript found in ouchless m

276 d that BTK-specific SCOs are able to correct aberrantly spliced BTK in B lymphocytes, including pro-B

277 Aberrantly spliced genes included a number of oncogenes,

278 ly, a number of these coregulated events are aberrantly spliced in mouse models and human patients wi

279 2-dependent introns have been reported to be aberrantly spliced in patient cells and animal models.

280 and ex vivo transcript analysis revealed an aberrantly spliced transcript, with intron 44 retained i

281 ses of telomere dysfunctional CMP identified aberrantly spliced transcripts linked to pathways releva

282 erence we attribute to preferential decay of aberrantly spliced transcripts.

283 are, exon-skipping events, which may reflect aberrantly spliced transcripts.

284 its activity, as inactive SnRK1 variants are aberrantly stable but recover normal degradation when ex

285 torage of histones in lipid droplets and the aberrantly structured chromosomes of invadolysin mutants

286 In this study, we found aberrantly sustained granulocyte production in Icsbp(-/-

287 ignaling expanded their dendritic fields and aberrantly synapsed with neighboring photoreceptors.

288 n IFT20-depleted cells, PDGFRalpha localizes aberrantly to the plasma membrane and is overactivated a

289 methylation at the promoter regions of genes aberrantly transcribed following l-DOPA treatment.

290 lation at many important regulatory areas of aberrantly transcribed genes.

291 Runx3-deficient CD8(+) TEFF cells aberrantly upregulated genes characteristic of follicula

292 ) and its product hydrogen sulfide (H2S) are aberrantly upregulated in colorectal cancers, where they

293 nd that a subset of ribosome-bound mRNAs was aberrantly upregulated in hippocampal CA1 neurons of Mec

294 iter lysine-specific demethylase 1 (LSD1) is aberrantly upregulated in many cancer types and its over

295 Lin28B is aberrantly upregulated in the childhood tumor neuroblast

296 At the same time, Runx2 is aberrantly upregulated in the medial layer of db/db aort

297 More than half of human cancers have aberrantly upregulated phosphoinositide signals; yet how

298 To learn whether synapses form and function aberrantly, we used electrophysiological and anatomical

299 permits a constitutive enhancer to interact aberrantly with the receptor tyrosine kinase gene PDGFRA

300 to the OB, the neuroblasts were distributed aberrantly within the radial dimension, and many immatur