ライフサイエンスコーパス: ability to initiate

1 This priming immunogen has demonstrated the ability to initiate a bnAb response in animal models, bu

2 tance of this protease may be related to its ability to initiate a proteolytic cascade, leading to th

3 n-gated barbed end capping proteins with the ability to initiate actin filaments from actin monomers

4 Purkinje cells showed deficiencies in their ability to initiate action potentials and support rapid,

5 on genes involved in these processes via its ability to initiate, activate, or repress transcription

6 cytokines, chemokines, and IDO, and in their ability to initiate allogeneic CD4(+) and CD8(+) memory

7 rin promotes platelet responsiveness via its ability to initiate alphaIIbbeta3-mediated outside-in si

8 Human NK cells are characterized by their ability to initiate an immediate and direct cytolytic re

9 Dendritic cells (DCs) have the unique ability to initiate an immune response in vivo by captur

10 e hyperaroused and have dramatically reduced abilities to initiate and maintain rest at night.

11 age dependent and results from the decreased ability to initiate and amplify lineages, defects in asy

12 results indicate that in budding yeast, the ability to initiate and complete the meiotic program as

13 re for FoxO1 endow all FoxO factors with the ability to initiate and dynamically modulate active chro

14 is a common sleep disorder that disrupts the ability to initiate and maintain restorative sleep, a be

15 state of myogenic precursor cells: i.e., the ability to initiate and maintain the differentiated stat

16 The ability to initiate and observe such electronic dynamics

17 subpopulation of tumor cells has the unique ability to initiate and perpetuate tumor growth; moreove

18 which may function like stem cells in their ability to initiate and propagate metastatic tumours.

19 ormal counterparts, and that their intrinsic ability to initiate and retain occupancy of these niches

20 The ability to initiate and sustain CD8(+) T cell responses

21 The ability to initiate and terminate sleep on command will

22 iated PR cleavage might be important for its ability to initiate APL.

23 aveolin-1 may, in part, be attributed to its ability to initiate apoptosis in rapidly dividing cells.

24 hares with the related APO-1/Fas antigen the ability to initiate apoptosis.

25 ls escape negative selection, yet retain the ability to initiate autoimmunity.

26 uption of the gene for dDia2 restores cells' ability to initiate blebs and thus migrate, though pseud

27 ion at early prophase and maintenance of the ability to initiate but not complete RAD51- and DMC1-med

28 ciprocal impairment of the recombinase's own ability to initiate catalysis.

29 exes, inhibited their cytotoxicity and their ability to initiate cell death.

30 (DCs) have been well characterized for their ability to initiate cell-mediated immune responses by st

31 eveloped to screen aromatic amines for their ability to initiate charge transfer by reductive electro

32 Light's ability to initiate chemistries largely independent of a

33 imulation of gene expression is due to DDT's ability to initiate crosstalk between MAPK (mitogen-acti

34 that a recombinant HCV NS5B protein has the ability to initiate de novo RNA synthesis in vitro.

35 The ability to initiate degradation of a substrate that had

36 t A (UVA; 320-400 nm), which differ in their ability to initiate DNA damage, cell signaling pathways

37 ty of partially mature SOD1 states and their ability to initiate fibrillation or be recruited by a gr

38 ecificity of T7RNAP for ribonucleotides, its ability to initiate from a single nucleotide, and the ab

39 ial RNA polymerase (Rpo41) has the intrinsic ability to initiate from promoters without its specifici

40 tercellular membrane fusion, unique in their ability to initiate fusion even without prior interactio

41 mucosa of a host is an important step in its ability to initiate gastrointestinal disease.

42 In addition, we studied its ability to initiate gene transcription by using microarr

43 growth initiation, whereas the nor mutant's ability to initiate growth was comparable with the wild-

44 nses, we directly tested their relevance and ability to initiate GVHD when presented by either the he

45 gration from skin, transgene expression, and ability to initiate humoral and cellular immune response

46 is typically immunosuppressed, blunting the ability to initiate immune responses.

47 or usages for cell entry, suggesting similar abilities to initiate infection in a new host.

48 nhibit infection does not correlate with its ability to initiate infection as measured by the complem

49 hwp1 homozygous null mutant is normal in its ability to initiate infection but deficient in its capac

50 and TRSB-NE2T191 was not due to an impaired ability to initiate infection.

51 extracellular adenosine triphosphate has the ability to initiate inflammation and is therefore referr

52 We screened multiple TLR agonists for their ability to initiate KSHV replication in latently infecte

53 ity of this MLL fusion for GMP cells and its ability to initiate leukemogenesis in conjunction with c

54 enuating HMMR in LUAD cells diminished their ability to initiate lung tumors and distant metastases.

55 on of recombinant herpesviruses and in their ability to initiate lytic infections at low multipliciti

56 role in allergic disease by virtue of their ability to initiate, maintain, and augment TH2 responses

57 lls and CC10-expressing Clara cells have the ability to initiate malignant transformation following t

58 The ability to initiate movements can be impaired in some br

59 One common example of such behaviors is our ability to initiate movements solely on the basis of an

60 role in heart development and its potential ability to initiate myocardial repair in injured adult t

61 ve been previously injured have an increased ability to initiate new axonal growth.

62 colytic flux may contribute to their reduced ability to initiate new immune responses in UV-irradiate

63 er strains were significantly delayed in the ability to initiate nodules on the primary root of the h

64 subunit that endows primase with the unique ability to initiate nucleic acid synthesis.

65 ce of fluticasone propionate (FP), and their ability to initiate or sustain classical activation, mim

66 The ability to initiate organs throughout the lifecycle is a

67 Together, these data demonstrate that the ability to initiate otolith formation is limited to a cr

68 esiding in the adult mouse pancreas have the ability to initiate Pancreatic and duodenal homeobox (Pd

69 gand particles to delineate a given ligand's ability to initiate phagocytosis, and purified human C1q

70 They lack the ability to initiate pheromone-induced G1 cell cycle arre

71 of the unique activity of DCs, such as their ability to initiate potent T helper cell type 1 response

72 y to HK binding and highly restricted in its ability to initiate prekallikrein or FXI activation.

73 polymerase (RNAP) confers on the enzyme the ability to initiate promoter-specific transcription.

74 The ability to initiate reactions with a flash of light and

75 d afferent input but may impair the neuron's ability to initiate recovery signaling for survival and

76 The ability to initiate reduction reactions by emitting elec

77 eats may share a common property, namely the ability to initiate repeat-mediated epigenetic changes t

78 somal fusion, the mutant was impaired in the ability to initiate replication between 4 and 8 h posten

79 y; however, the mutants are blocked in their ability to initiate reverse transcription in infected ce

80 es gain access to lymph nodes owing to their ability to initiate rolling along specialized high endot

81 purified cyclin A/cdk2 in vitro reduced its ability to initiate simian virus 40 (SV40) DNA replicati

82 main IV is unique in this linkage and in the ability to initiate slow inactivation in sodium channels

83 , STARCH SYNTHASE 4 (SS4) is impaired in its ability to initiate starch granules; its chloroplasts ra

84 miR173 was unique from other miRNAs in its ability to initiate TAS1c-based syn-tasiRNA formation.

85 ion of the BLRF2 gene, but did not alter its ability to initiate the lytic cycle or to synergize with

86 find that aged mother cells show a decreased ability to initiate the meiotic program and fail to expr

87 thelial cells express numerous RTKs with the ability to initiate the phosphorylation (activation) of

88 e basement membrane defects by examining its ability to initiate the plasminogen/plasmin proteolytic

89 the HisZ-HisG octameric ATP-PRT acquired the ability to initiate the synthesis of a key metabolic int

90 iption; however, this mutation abolished its ability to initiate the viral lytic cascade.

91 chain, MHC A and MHC B, that differ in their ability to initiate thick filament assembly.

92 ated form of tissue factor (tTF) had limited ability to initiate thrombosis when free in the circulat

93 dependent promoters but reduces the enzyme's ability to initiate transcription initiation and/or exit

94 structurally plastic RNA element confers the ability to initiate translation internally, and activity

95 subpopulation in the tumors that possess the ability to initiate tumor growth and sustain self-renewa

96 ted with an impaired osteogenic fate and the ability to initiate tumor growth through the generation

97 d purple sea urchin RAG1-like, have a latent ability to initiate V(D)J recombination when coexpressed

98 us reverse transcriptase (RT) has the unique ability to initiate viral DNA synthesis using RT itself