ライフサイエンスコーパス: able

1 When tested on ten able-bodied individuals and one transradial amputee, the

2 driven classifications searchable and query-able, but fulfilling this potential requires standardize

3 ic labelling techniques in zebrafish we were able, for the first time, to dynamically track cell beha

4 ling groups to show an evolution from models able only to deal with land-cover change to more sophist

5 However no vaccine was able so far to induce bnAbs demanding their expensive bi

6 Selective ER downregulators (SERDs) are able to ablate ER and thus, theoretically, to prevent su

7 xo dicopper(II) complex 2, while 3 itself is able to abstract H-atoms from weaker X-H bonds such as T

8 ase-rich enzyme preparations were presumably able to access the inner rhamnogalacturonan I dominant c

9 e datasets showed that the ELS algorithm was able to accurately estimate frequencies of gametes and o

10 The smartphone spectrometer is able to achieve a resolution of 5 nm in a wavelength ra

11 The resulting architecture is able to achieve accurate results with relatively few par

12 on, and capping linker installation, we were able to achieve the highest Th wt % in mono- and biactin

13 ed for adults with food allergy who were not able to acquire immune tolerance during childhood.

14 st parvovirus whose NS1 has been shown to be able to activate all three PI3KKs (ATM, ATR, and DNA-PKc

15 and dying cells which, when crystalized, is able to activate the NLRP3 inflammasome.

16 survive depends on its sensory systems being able to adapt to a wide range of environmental condition

17 mulated loss of contractility (2% strain) is able to additionally induce increased CF release of infl

18 mmetrical, rich in Arg and Trp residues, and able to adopt a native RTD-1-like structure.

19 Both variables were able to affect cell viability, and the release of solubl

20 The obtained polymers were able to amplify the intensity and the duration of the li

21 genomic datasets and simulated data, we are able to analyze how accurate the output of the variant c

22 twork of microtubules in the spindle must be able to apply and sustain large forces to maintain spind

23 neovessels form from endothelial progenitors able to assemble the intimal layers.

24 enzyme and two mutagenesis variants, we are able to assign the IR signals of the individual CN(-) li

25 mance as grammar + processing will always be able to attribute psycholinguistic data to processing ra

26 tioned stimuli, rendering these stimuli less able to be learned about and less able to control fear o

27 sion profiles from single stressor data were able to better predict effects on reproduction compared

28 units, but the aforementioned substances are able to bind only a few of them.

29 s, is unique amongst the MKP family in being able to bind to both ERK3 and ERK4.

30 ationic cell-penetrating peptides (CPPs) are able to bind to cell membranes, thus promoting cell inte

31 idine residues, we demonstrated that MsrQ is able to bind two b-type hemes through the histidine resi

32 Flunarizine was also able to block the injurious increase of Angpt-2 in murin

33 Both PIV5/F and PIV5/G were also able to boost neutralization titers in RSV-preexposed Af

34 nd the particle number distribution, we were able to calculate the ENM mass remaining in suspension.

35 Nevertheless, it is only able to capture a limited view of macula and does not sh

36 density functional on malonaldehyde and are able to capture the intramolecular proton transfer proce

37 d phases and define paracrystalline surfaces able to catalyse specific enantioselective chemical reac

38 that among PLK family members, PLK3 is also able to catalyze alpha-syn phosphorylation and degradati

39 Notably, 12 was able to cause concentration-dependent inhibition of cell

40 ms oriented within the macrocycle cavity are able to chelate copper(I) endotopically.

41 on chelator, deferiprone, is well tolerated, able to chelate iron from various brain regions and impr

42 tative of each harvest year, the models were able to classify unknown samples correctly (100% correct

43 tions yield semi-immobilized FLPs, which are able to cleave dihydrogen heterolytically at ambient tem

44 Beetles able to colonize live tree tissues are most likely to be

45 Mtb and related species may be able to combat this harsh acidic environment which conta

46 esting that spontaneous neurotransmission is able to communicate independently with the postsynaptic

47 tic banding procedure; however the cells are able to compensate Ca(2+) homeostasis in an efficient wa

48 The hyPAD is able to concentrate a range of analytes, including small

49 We were able to confirm expression of SMAD3 in intact and degrad

50 omas, demonstrating that residual Tregs were able to control CD8(+) T-cell responses against the tumo

51 imuli less able to be learned about and less able to control fear or safety behaviors.

52 on scattering, under conditions where we are able to control the redox state of the enzyme precisely.

53 olecules, and when bound to plasminogen, was able to convert plasminogen to plasmin in the presence o

54 s) We show that only GPI-anchored PrP(C) was able to convert to PrP(res) and able to serially propaga

55 lthy from adenomatous parathyroid tissue was able to correctly classify all samples in the calibratio

56 ch performs both tasks simultaneously and is able to couple light at normal incidence and near normal

57 0(6)), and the integrated F-P filters, being able to cover whole visible spectrum, successfully modul

58 ed model, and termed as dMAGA-FCMD, which is able to deal with large-scale FCMs with up to 500 nodes.

59 Further, the algorithms are able to deal with networks containing different combinat

60 rbonate is only formed when the electrode is able to decompose/oxidize MeOH to form (adsorbed) methox

61 a supervised machine learning algorithm, are able to deliver behaviorally triggered stimuli to flies

62 Using the inkjet printing technology, we are able to deliver multiple 100pico-liter (pL) volume dropl

63 the family design of the sample, we are also able to demonstrate that epigenetic aging and white matt

64 MAS and high magnetic field (1 GHz), we were able to describe the motions of the residues of the beta

65 Currently there is a lack of models able to describe the thermodynamic stability of these 'm

66 that several P2X receptors, including those able to desensitize, are permeable not only to NMDG(+) b

67 trate profiling and structural data, we were able to design a selective peptide inhibitor of APN that

68 nfrared fluorescent psiRGDechi derivative is able to detect alphavbeta3 integrin in human melanoma xe

69 Therefore, it is important to be able to detect CVD biomarkers early so that patients can

70 that the mitochondria-based piezosensors are able to detect ion fluxes and thus be utilized for drug

71 The new assay was able to detect RNA from five currently used vaccine stra

72 The method was able to detect several species of crab spiked into compl

73 ation diversity were even closer, as we were able to detect some differences between population group

74 n reaction in the crystalline state, we were able to detect the intermediate radical pairs within the

75 s with three prenyltransferases, and we were able to detect turnover in >55% of the cases.

76 We were able to detect urinary black carbon in all children, wit

77 In addition, these techniques are able to determine the effect of TFA on the stability of

78 Furthermore, the presented chiral assay is able to determine the enantiomeric excess (ee) of D-cyst

79 g symmetries of the Fourier transform we are able to determine the phase directly from straightforwar

80 is in the roots of the 80-90% of land plants able to develop rhizobial and/or mycorrhizal endosymbios

81 This technique is able to differentiate composition on the nanoscale and e

82 These DNAm signatures were able to differentiate pathogenic mutations in these two

83 igraine calcium channel (CC) blocker - being able to diminish intracellular Angpt-2 protein in a time

84 Subjective experience suggests that we are able to direct our auditory attention independent of our

85 fluorophore to the dendrimer is 1:1, we were able to directly compare uptake kinetics, the mode of up

86 Conversely, stem cells are also able to directly modulate the immune response through th

87 As, in particular, saturated FAs (sFAs), are able to directly trigger macrophage cell death.

88 The signature was able to discriminate between patients with severe sympto

89 le separate IRMS and RRS investigations were able to discriminate only samples from Sicily and Latium

90 DA" and Support Vectors Machines "SVM"), was able to discriminate the wine vinegar category within ea

91 dback and analysis with an algorithm that is able to distinguish and select the most reactive pathway

92 a need for a rapid and cost-effective assay able to distinguish between pluripotent and nonpluripote

93 eterogeneity, our prediction models were not able to distinguish by sample types.

94 MRI brain lesion distribution criteria were able to distinguish RRMS with a sensitivity of 90.9% and

95 ests for vlhA3.04a, vlhA3.05, and mg0359 was able to distinguish the M. gallisepticum ts-11 vaccine s

96 Further, we identify promoters able to drive strong expression in multiple tissue/organ

97 e emergence of potent CD8(+) T-cell immunity able to durably suppress virus replication.

98 For predators able to eat only a few species (i.e., specialists), low

99 ine reserves are globally interconnected and able to effectively seed areas, where fisheries are most

100 Importantly, HL2-m5 is able to effectively suppress Shh-mediated hedgehog signa

101 ant physically motivated constraints, we are able to efficiently reconstruct stress fields with local

102 ks) demonstrate that this PDE4D inhibitor is able to enhance memory in AD transgenic mice and concomi

103 Nanocarrier and diagnostic ultrasound are able to enhance the drug penetration for achieving impro

104 In all its diversity, this discipline is able to enrich the debate on medical issues, thanks to m

105 Circadian clocks must be able to entrain to time-varying signals to keep their os

106 Using this system, we have been able to establish which decorations underpin the formati

107 Using the DFT calculations, we have been able to estimate in the photoinduced isomer the distance

108 ate as an extracellular glycosyltransferase, able to exert a "glycan remodelling" process, even at di

109 o the development of a mounted warrior elite able to expand polities (political units that cohere via

110 Our fitted model was able to explain most of the variability in GEP at hourly

111 nd genome completeness as long fragments are able to extend paths into problematic or repetitive regi

112 imental indicates the novel microreactor was able to extract 93% phenol and 82% Cu(2+) from external

113 oped the IsotopicLabelling R package, a tool able to extract and analyze isotopic patterns from liqui

114 The N-terminus of MerA is able to extract the bound Pb(VI) but not the bound Sn(IV

115 compared to existing methods, our method is able to find significant covariances and also to control

116 Being able to focus on a complex task and inhibit unwanted act

117 ous study of bee spatial navigation has been able to follow animals' movement during learning; we tra

118 s an ideal semiconductor interface, which is able to form a homogenous layer on the electrode surface

119 ta also excretes 10X more farnesol and while able to form hyphae, it cannot maintain hyphae.

120 Thus, SmI2(H2O)n should be able to form very weak C-H bonds.

121 the better antihypersensitive profile being able to fully counteract the oxaliplatin-induced neuropa

122 c spatial and spectrotemporal processes were able to fully explain motion-induced activation in most

123 ic lineages indicates that exogenous gdf3 is able to fully rescue mutants only when co-expressed with

124 Interneurons are potentially able to function on both a highly localized, synapse-spe

125 various PTC-inducing non-sense mutations is able to generate and present epitopes downstream of the

126 The algorithm is able to generate approximate oligomer solutions quickly

127 Our evaluation shows that Seqping was able to generate better gene predictions compared to thr

128 Two-dimensional (2D) separations are able to generate significantly higher peak capacities th

129 Thus, we are able to generate testable mechanistic hypotheses of the

130 at species with increasing trends are better able to geographically track climate change compared to

131 (Populus euphratica), a so-called hero tree able to grow in the desert.

132 Importantly, MAJIQ-SPEL is able to handle both classical (binary) and complex, non-

133 (TMRMR) feature selection approach, which is able to handle multivariate temporal data without previo

134 ing shared motifs in core sequences, we were able to highlight key conserved residues driving essenti

135 h an expert system of mitotic progression is able to highlight the complexity of the mechanisms requi

136 action followed by HPLC-MS analysis, and was able to identify 14 fungus secondary metabolites, namely

137 AlignAndTrimVariants shows that UPS-indel is able to identify 456,352 more redundant indels in dbSNP;

138 nd subsequent functional validation, we were able to identify a MHCII-restricted CD4 T cell epitope,

139 lack single-cell epigenomic assays that are able to identify and characterize them.

140 With our methodology we were not able to identify any functional deficits in mutations I8

141 In addition, we were able to identify effects on gene expression of rare geni

142 hat are robust to platform/batch effects and able to identify perturbed pathways in individual sample

143 Additionally, we were able to identify putative molybdopterin synthase associa

144 spectroscopic technique is presented that is able to identify rapid changes in the bending modulus an

145 Using cytometry by time-of-flight, we were able to identify several major time-dependent phenotypic

146 a pharmacologic inhibitor of mTORC1, we were able to identify six T-bet phosphorylation sites.

147 Using this approach we were able to identify two novel cis-regulatory regions, which

148 ith haRPA, the so-called viability haRPA, is able to identify viable Legionella on DNA microarrays.

149 ion model, CTLA-4 blockade in particular was able to improve control of viral replication.

150 Baseline slow walkers who were able to improve the 6MWT distance presented with signifi

151 The IO-LAHP NPs are able to induce efficient apoptotic cancer cell death bot

152 with anti-IAPP-specific antibodies were not able to induce IAPP aggregation.

153 d C1-epimeric monomeric nuphar analogous are able to induce rapid apoptosis.

154 mber of chitinase-like protein family (CLPs) able to induce the proliferation of imaginal disc cells

155 ntrol mutant MEK expression in vivo, we were able to induce tumor regression and significantly increa

156 nt of drug interventions for a virus that is able to infect a wide range of tissues and cell types re

157 ate that LP avian H7 influenza A viruses are able to infect and cause disease in mammals without prio

158 ons could prove that l-pyroglutamic acid was able to influence non-enzymatic browning reactions.

159 ts suggest that individual granule cells are able to influence relatively large groups of MCs and tuf

160 he other hand, polyphenols from guarana were able to inhibit alpha-glucosidase and alpha-amylase acti

161 neuron primary culture, both Nanobodies were able to inhibit endogenous EphA4-mediated growth-cone co

162 the 2009 pandemic H1N1 (pH1N1) virus is not able to inhibit general gene expression.

163 These compounds are able to inhibit GSK3beta and induce the Nrf2 phase II an

164 multiple megaspore mother cells, which were able to initiate gametogenesis.

165 (MUTYH in humans) adenine DNA glycosylase is able to initiate the repair of A:oxoG by selectively cle

166 esults boosted the research of new compounds able to interfere with HPPD activity to be used for the

167 M.AluI, M.CviPI, M.HhaI, and M.EcoGII were able to introduce (5m)C or (N6m)A into 9 g DNA as confir

168 invasion, with more flexible species better able to invade.

169 nous at the nanoscale, but specific ions are able to locally alter molecular organization and mobilit

170 n sub-Saharan Africa, yet few facilities are able to maintain long-term surveillance.

171 dehydrogenase 1(Gpd1p)-dependent shuttle are able to maintain the intraperoxisomal redox balance.

172 Nongeneticist providers may be able to manage WGS results appropriately, but WGS may pr

173 rmeabilization and immune cell activation is able to markedly increase therapy response in silico The

174 nscript abundance in the F1 hybrids, we were able to measure the abundance of cis- and trans-regulato

175 ive host molecule has been described that is able to mechanically twist a bound molecular guest, and

176 es in many cell signaling pathways that were able to mediate significant decreases in aggregate level

177 CHO cell fibronectins were able to mediate the binding of a diverse panel of gp120

178 uding the whole-gene cluster, was eventually able to merge the neighboring TADs into a single structu

179 g a single guide RNA, dCas9-SunTag-DNMT3A is able to methylate a 4.5-kb genomic region and repress HO

180 However, most of receptors able to modify contractility and other intracellular res

181 an additional mechanism by which GABABRs are able to modulate fast synaptic inhibition.

182 of dimethyl sulfoxide (DMSO), the adduct is able to move to a solvent-exposed conformation, which en

183 e lysines from the two other domains are not able to move.

184 e realization of smartphone-based biosensors able to non-invasively detect a large variety of analyte

185 These different isoforms are able to nucleate or frustrate the assembly of each other

186 lowing the loss of GFP fluorescence, we were able to observe the cells that had undergone targeted mu

187 Using F-PTS1 we are able to observe the pH conditions inside glycosomes in r

188 there are no commercially available devices able to obtain ultra-wide-field OCT or OCTA images in ne

189 ing generates species-specific HMMs that are able to offer unbiased gene predictions.

190 Thus prepared BioCapacitor based circuit was able to operate an ultra-low-power microcontroller conti

191 nic polymer are reported, which are uniquely able to operate at bandwidths up to 1.5 kHz whilst maint

192 y efficacious vaccine candidate; when we are able to optimize the immunization regimen (dose, interva

193 of neural systems identification, AMA may be able to overcome a fundamental limitation of standard su

194 dented series of O-type species (O(MeAN)-LA) able to oxidize C-H and O-H bonds.

195 at about the same time the Leishmania became able to parasitize vertebrates.

196 Lab-on-Chip are miniaturized systems able to perform biomolecular analysis in shorter time an

197 the cowpea chlorotic mottle virus (CCMV) are able to perform catalysis after introduction of the His-

198 idence shows that some plant virus RdRPs are able to perform replication in trans of genomic or DI RN

199 cles of rest-activity and food intake or are able to persist in vitro in a cell-autonomous manner.

200 antly assemble by selective survival of taxa able to persist under extreme energy limitation.

201 able model using routine laboratory data was able to predict advanced chronic kidney disease followin

202 A miR628-5p value above 1.336 was able to predict CAV with a sensitivity of 72% and a spec

203 The Sino-Nasal Outcome Test score might be able to predict more severe reactions and merits further

204 The model was able to predict participant performance in motor learnin

205 ere, we developed an algorithm, TransDetect, able to predict TF combinations controlling the expressi

206 trast to the direct use of FBA, SteadyCom is able to predict the change in species abundance in respo

207 the measured capacitance signal, and we were able to predict the contribution of endocytosis to the m

208 We were able to predict the proportion of cardiomyocytes many da

209 lovirus pp65 or influenza hemagglutinin were able to present the antigens to autologous antigen-speci

210 ential to transform food in functional food, able to prevent a variety of chronic diseases associated

211 ion of a water softener in early life may be able to prevent AD development.

212 n due to the paucity of experimental methods able to probe the mobility and density of the FG-polypep

213 he activated UCNP@mSiO2-Dopa nanoplatform is able to produce a pronounced photothermal effect, that e

214 With nearly complete success, we are able to produce a strain between any two target nodes in

215 Furthermore, this approach was able to produce a targeted autosome loss in aneuploid mo

216 hat the updated jump-walking simulations are able to produce equilibrium isotherms which are typicall

217 l crystals requires a mass production method able to produce heterostructures of arbitrary complexity

218 eriments demonstrate that the CFF process is able to produce SRMs with uniform size distribution, lar

219 b' fragments in the lungs but PEGylation was able to prolong their presence in both the healthy and i

220 s of reduced glutathione (1.0 and 2.0%) were able to promote a whiter color and a low free 5-hydroxym

221 linked with allergic respiratory disease is able to promote antiviral host defenses against the infl

222 , a virus-like particle (VLP) known as Rv21, able to provide 100% sterile protection against a string

223 On this basis, we are able to provide a better understanding of the complex re

224 By combining these strategies, we were able to provide a causal link between DEE and the follow

225 Most centres were able to provide diagnostic challenges to antibiotics [40

226 Furthermore, we were able to quantify a biological characteristic of macular

227 onstrate that the sensor is selective and is able to quantify diclofenac in tap water.

228 FASTmiR122 was able to quantitatively detect the differences in miR122

229 Many laboratories reported being able to quickly correct the minor deficiencies identifie

230 hese analyses suggest that CSmetaPred_poc is able to rank putative catalytic residues at lower (bette

231 from TBA(+) modified Aquivion ionomers were able to reach maximum power densities (Pmax) up to 1.5 t

232 Herein we report a domino protocol able to reach regioselectively thiazolylidene systems by

233 b which was immobilized on the test line was able to recognize both organophosphorus BChE adducts (OP

234 ts, the textile sensor is demonstrated to be able to recognize finger movement, hand gestures, acoust

235 pithelial layer expressing K12 and PAX6, and able to recover function in an animal model of corneal e

236 o examine whether molecular hydrogen (H2) is able to reduce oxidative stress after corneal damage ind

237 The compounds were able to reduce QS-regulated virulence factors (elastase,

238 urine macrophages showed that FPW extract is able to reduce the LPS-induced expression of pro-inflamm

239 tively impact virulence, and that aphids are able to reduce VPS52 levels during infestation, indicati

240 th the wound healing process and may also be able to regulate the responsiveness of these cells to EG

241 rized Legionella effectors that appear to be able to regulate yeast vacuolar fusion.

242 The resulting POP is able to remove aqueous and airborne mercury with uptake

243 need to develop new synthetic network models able to replicate controllability properties of real-wor

244 highly proliferative Lgr5(-) cells that are able to repopulate entire glands, including the base, up

245 To examine whether patients are willing and able to report their symptomatic AEs in multicenter tria

246 With this model, we were able to reproduce measured PNS thresholds of two leg/arm

247 GF-transformed cells; however, only EGFR was able to rescue the phenotype in cells lacking both RTKs

248 ventional transmission based THz-TDS and are able to resolve conductivity changes in response to indu

249 ting a majority of inhibitory neurons may be able to resolve this question.

250 fire salamander (Salamandra salamandra), was able to retain learned spatial information after a perio

251 y examples of bioinspired materials that are able to reversibly alter their stiffness, shape, porosit

252 tes of the rodent parasite P. berghei we are able to robustly quantify parasite infection of hepatocy

253 ap from exogenous d-Arap, both proteins were able to salvage l-fucose to GDP-fucose.

254 icularly in the ferric form, such that it is able to sample a broad conformational space.

255 ow the RSI correlates with reactivity and is able to search chemical space using the most reactive pa

256 The model was readily able to secrete 140 mm HCO3(-) .

257 We have defined genetic markers able to segregate stable HIV-1-controllers from those wh

258 from background noise, female treefrogs are able to select among individual males advertising for ma

259 netic control suggests that breeders will be able to select semi-independently for mean phenotype val

260 nhibit the right frontopolar cortex, we were able to selectively inhibit directed exploration while l

261 ter marks a long-lived basal cell population able to self-renew, proliferate, and generate differenti

262 Nevertheless, NK cells were able to sense alterations of HLA-C expression demonstrat

263 In the majority of cases, we were able to sequence the ITS region from powdered mycelium s

264 d PrP(C) was able to convert to PrP(res) and able to serially propagate.

265 hese CD4(-) CD8alphaalpha T cells are likely able to serve as an immunophenotype capable of Th1, foll

266 To be able to sexually transmit for months after the clearance

267 Based on the MCD structure, we were able to shift substrate specificity of MCD toward succin

268 Therefore, we were able to show that oil-in-water emulsions stabilized by p

269 erruptions of preoperative posturing we were able to show, in a prospective and ethically acceptable

270 tty acids and main energy-redox processes is able to simulate the relationship between VO2 and H2O2 e

271 iology, the role of multifunctional proteins able to simultaneously coordinate/modulate several cellu

272 Furthermore, we are able to simultaneously detect glucose and fatty acid upt

273 sitive effects on neuronal pathways that are able to slow down the progression of Alzheimer's disease

274 as purified recombinant apo(a) variants were able to specifically inhibit HCV by interacting with inf

275 atures, this electrochemical immunosensor is able to specifically recognize and detect the PspA pepti

276 on that the slow delayed rectifier is better able to stabilize the action potential and suppress pro-

277 Furthermore, LESA-MS was able to successfully differentiate between simple steato

278 The authors were also able to successfully remove the virus and examine the ro

279 eover, recombinant galectin-10 by itself was able to suppress T cell proliferation.

280 has prompted suggestions that species may be able to survive future climate change in pockets of suit

281 Moreover, while DeltacheY2 spirochetes are able to survive normally in the Ixodes ticks, mice fed u

282 Importantly, this mutation was able to sustain 15% of wild-type transport activity, whe

283 mechanism suggests that stony corals may be able to sustain calcification even under lower pH condit

284 ressing recombinant virus (rLBNSE-IL-7) were able to sustain VNA levels much longer than those elicit

285 support the idea that bipolar cells might be able to synapse with reintroduced photoreceptors, thereb

286 aveA strain and identified revertant mutants able to synthesize ST, among them RM1.

287 ing factor tristetraprolin, which we show is able to target the IFN-beta mRNA.

288 bel Lecture, J. Stoddart describes how being able to template the formation of mechanically interlock

289 Our findings show that human NK cells are able to terminate their functional activity without the

290 fate may depend on the degree to which it is able to track a change in the optimum timing either via

291 We were able to track the community diversity at high temporal r

292 lly, SERCA2a 971-990-sensitized T cells were able to transfer disease to naive recipients.

293 d on a wiping paper towel in a trash can was able to transform ammonium sulfate and ammonium nitrate

294 Consequently, gut dysbiosis was able to trigger the development of encephalitogenic T ce

295 rf2 and its negative regulator, Keap1 and is able to up-regulate the expression of autophagy-associat

296 use of biomarkers and how clinicians may be able to use them in the future to predict the course of

297 We are able to use these linear correlations to improve reactio

298 Settler cells are better able to withstand harsh conditions like drought and alka

299 ctures was fabricated and demonstrated to be able to work up to 200( ) degrees C.

300 8 months after transplantation surgery he is able to write and feed, toilet, and dress himself more i