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1 reveal temporal ventriloquism, the effect is abolished.
2 attenuated and its effects on BP and HR are abolished.
3 eously, residual hemolytic activity could be abolished.
4 d to these membranes, cleavage in loop 4 was abolished.
5 f RV dyssynchrony pattern were significantly abolished.
6 these protective effects of adiponectin were abolished.
7 ntrolled only by the pseudokinase IRAK2) was abolished.
8 r, spike modulation by somatic prepulses was abolished.
9 ave responses of electroretinogram (ERG) are abolished.
10 In vivo, a 2.5 mg/kg dose of (+)-pentazocine abolished (11)C-Me-NB1-specific binding, indicating an i
12 (CaMKII) and also that inhibition of CaMKII abolishes 8-pCPT-AM-induced increases in STOC activity.
13 Instead, depletion of cardiolipin synthase 1 abolished abacavir-induced IL-1beta secretion, suggestin
14 ogression by employing integrin alpha9beta1, abolishing actin stress fiber formation, inhibiting YAP
15 Mutagenizing Met-915 or Met-956 selectively abolishes activation by isoflurane and propofol without
16 nant polypeptide arginine deiminase 4 (PAD4) abolished ADAMDEC1-catalyzed pro-EGF1020-1027 peptidolys
18 wth by approximately 40%; these effects were abolished after TGR5 reduction by short hairpin RNA.
19 and challenged mice, anti-IgE mAb treatment abolished AHR 24 hour and 48 hour after the last challen
21 ng the Phe by small amino acid substitutions abolished alphaLbeta2 binding with soluble and immobiliz
22 strong membrane interaction of the multimer-abolishing alphaS variant but also restored multimerizat
25 n contrast, locomotor effects of heroin were abolished, and heroin-induced catalepsy was increased.
26 with a neutral side chain, the pH effect is abolished, and high-affinity binding is observed until L
29 e NAD recovery, improved general health, and abolished attrition produced by a near maximum-tolerated
30 introduction of CD22 ligands in RBCs should abolish B cell activation toward its cognate Ag on the s
31 ense change (S98R) in a case that completely abolished BAP1 deubiquitinase activity was identified.
34 without affecting autophosphorylation, H917A abolished both the lipid and protein kinase activities o
35 on in auxin levels, perception, or signaling abolishes both the extracellular acidification and cellu
36 -function mutations of KIB1 and its homologs abolished BR-induced BIN2 degradation and caused severe
43 d psychomotor response to cocaine, which was abolished by disruption of the DC pathway, but not the s
45 hese protective effects produced by XMJ were abolished by eNOS inhibitor L-NAME or specific eNOS siRN
47 in the absence of extracellular Ca(2+) , was abolished by LaCl3 and was attenuated approximately 70%
50 of pro-inflammatory cytokines/chemokines are abolished by PARP1 ablation or inhibition, or blocked in
51 coupled with extracellular potassium shifts, abolished by pharmacological blockade of GABAA receptors
52 ts in oncogenic toxicity; this effect can be abolished by pharmacological inhibition of Mek to restor
53 pressor and sympathoexcitatory effects were abolished by pretreatment of the RVLM with the vasopress
55 eralgesic effects of sigma-1 antagonism were abolished by reducing the neutrophil load with in vivo a
56 mine D3 receptors (D3R), as its effects were abolished by selective D3R antagonists and absent in D3R
65 tracellular matrix molecules and effectively abolish contact inhibition of locomotion (CIL) of the ce
67 (driven by underlying genetic mutations that abolish critical proteins required for normal function o
68 at the Igf2-H19 imprint control region that abolishes CTCF insulator activity, resulting in bialleli
69 uced proliferation inhibition and apoptosis, abolished cytarabine-induced S and G2/M cell cycle arres
70 inositide- (PI) binding domain of Daple, Akt abolishes Daple's ability to bind PI3-P-enriched endosom
71 Deletion of cvpA-purF, or of purF alone, abolished de novo purine biosynthesis but did not impact
73 of Arg36 (R36W) or Arg35 (R35H/L) completely abolished DNA binding, mutation of Arg60 (R60Q) signific
79 ing levels of TNFalpha in PGRN knockout mice abolished excessive self-grooming and the associated hyp
80 sing a mouse genetic approach, we found that abolishing expression of CNG channels prolongs rod survi
81 istration of a small-molecule JAK inhibitor, abolishes FGF19-induced tumorigenesis, while the regulat
85 u-260 as an essential residue whose mutation abolished function without affecting stability or transp
86 al (but not contralateral) nostril, known to abolish gamma oscillations in the piriform cortex, stron
88 t only impaired bSC dendritogenesis but also abolished glutamate transmission-induced dendritic overg
89 eracts with GroEL; however, mutations of I25 abolish GroES-GroEL interaction due to the seven-fold mu
90 osphorylation site mutants nearly completely abolished HAC1 splicing, induction of KAR2, PDI1, and be
92 amelioration of ER stress in mice completely abolishes high fat diet-induced upregulation of TRIP-Br2
93 onstrated that MW thermal heating completely abolished honey antibacterial activity whereas conventio
96 S2 C-terminal (721)QRLIAP motif attenuate or abolish human MutLalpha interaction with PCNA, as well a
97 liferator-activated receptor gamma inhibitor abolished hydrogen sulfide-mediated protection in ventil
99 nt with novel histone deacetylase inhibitors abolished hypoxia-induced DUSP2 downregulation, COX-2 ov
100 90 s.d.), a rare in-frame deletion in FCGR2B abolishing IgG binding to the encoded receptor (p.Asn106
101 t or by a therapeutic and systemic strategy, abolished IL-1beta- and GLAST-dependent synaptopathy in
108 erved that DSB-induced H4K16 acetylation was abolished in cells upon depletion of the histone methylt
111 s in which ERK/MAPK signaling was completely abolished in each of the two distinct classes of medium
112 milarly, disulfide heterodimer formation was abolished in H9C2 cells expressing both MKK3 and p38alph
113 L, cholesteryl esters and triglycerides were abolished in Hilpda cKO macrophages, independent of the
114 ably, the protective effect of etifoxine was abolished in mice depleted of microglia by using a colon
115 TLR and IL-1R responses are weak but not abolished in mice lacking IRAK-1, whereas the role of IR
116 improvement in glucose tolerance by cIH was abolished in muscle-specific AMPKalpha1alpha2-deficient
117 ommissural layer 5 mPFC pyramidal neurons is abolished in neuropathic pain rats due to a severe reduc
118 rbations of calcium-mediated signalling, but abolished in null mutants of the pH-responsive transcrip
121 ct-dependent manner, and both activities are abolished in the absence of the phosphodiestrase YmdB, s
122 fusion of phospholipids and sphingolipids is abolished in the GPMVs, whereas transient nanodomain inc
123 Results ERalpha transcriptional function was abolished in the mutated 231 G521R ER cells despite appr
126 biquitylation of IRAK1, IRAK4, and MyD88 was abolished in TRAF6/Pellino1/Pellino2 triple-knockout (KO
127 of MSCs since inhibition of this chemotaxis abolished increased neutrophil recruitment and tumor met
129 t mutations in the RPA32 subunit of RPA that abolish interaction with RFWD3 also inhibit ICL repair,
130 etic nutrients is an appropriate strategy to abolish interference of endogenous or undesirable exogen
133 s agonist R848, chemical inhibition of IRAK4 abolished IRF5 translocation to the nucleus and thus pre
136 midation activity of hTG2 and allosterically abolish its GTP binding ability with a high degree of se
138 ys, that phosphorylation of YY1 at this site abolishes its DNA binding activity in vitro and in vivo.
139 acetylation sites (K242, 259, 290 and 569R) abolished JNK1 binding and failed to induce apoptosis.
142 eased photosynthesis performance, and almost abolished light-dependent reduction of fructose-1,6-bisp
143 (NF-kappaB) and that inhibition of NF-kappaB abolished LINC00305-mediated activation of cytokine expr
148 Vitamin D receptor (VDR) knockdown partly abolished MART-10-induced inhibition of NGAL and cell gr
151 tion and genetic knockout of TLR4 completely abolished ML exosome-induced cytokine production in macr
152 hly regulated flagellar assembly process can abolish motility and cause negative physiological outcom
156 pilins, where E5 residue substitutions also abolish N-methylation, the E5A variant of T2SS pseudopil
157 ockage of the STIM1-Orai pathway effectively abolishes neurite outgrowth of PC-12 cells stimulated by
160 1-SH2 helix, the relay helix, and the lever, abolishes nonmuscle myosin-2 specific kinetic signatures
161 In proliferating cells, formin inhibition abolishes nuclear transport and initiation of DNA replic
164 t staphylococcal lipoteichoic acid (LTA) was abolished only in the index case individual, the only fa
165 (SDHC) subunits by shRNA in B16rho(0) cells abolished or significantly retarded their ability to for
169 ockers (terfenadine, ErgToxin-1, and E-4031) abolished persistent firing and the underlying increase
170 ionally, mutations of serines 688/689, which abolish PIH1D1 binding, also resulted in decreased MRE11
171 and inhibition of Akt activity significantly abolished platelet-induced EOMA cell proliferation in vi
175 ents activity-induced synapse maturation and abolishes post-tetanic potentiation, a form of synaptic
176 yclosporin A decreased protein synthesis and abolished proliferation in wild-type tubular cells, but
178 -tetramer interface and the active sites can abolish Pseudomonas aeruginosa growth in a defined mediu
182 the presence of single nucleotide insertion abolishes recognition of an adjacent base triplet by all
183 ation, eliminated KCNQ1 surface-density, and abolished reconstituted K(+) currents without affecting
184 alpha-glucosidase activity almost completely abolished residual glucose production by G6pc-deficient
185 liferation and migration, lower retinol, and abolished retinoid X receptor/retinoid A receptor transc
188 , of principal cells can reliably shorten or abolish seizures in vitro Our work suggests that targete
189 concentrations (>0.5 mum) and BLT2 agonists abolished sensitization of the TRPV1-mediated calcium in
192 erature, blocking ATP hydrolysis effectively abolished slow endocytosis and rapid endocytosis but onl
196 ation loop decreased, but did not completely abolish, splicing of HAC1 mRNA, induction of KAR2 and PD
197 acetylimination disrupts Stat3 dimerization, abolishes Stat3 transcription activity, and restricts ce
199 y, depletion of PGC-1alpha in chemoAML cells abolished such induction of mitochondrial metabolism and
200 C intact, whereas branching MT nucleation is abolished, suggesting that TPX2 may activate gamma-TuRC
201 itution of E171 (within the consensus motif) abolished SUMOylation, significantly increased the half-
204 PPARalpha blockade by the antagonist GW6471 abolish the effect of clofibrate on radiosensitization.
206 c cancer-associated Parkin mutations largely abolish the functions of Parkin to ubiquitinate HIF-1alp
207 ventional MV, and to replace MV and minimize/abolish the harmful effects of ventilator-induced lung i
208 ed Palindromic Repeats (CRISPR)/Cas9 did not abolish the inhibitory effects of AICAR on RPE CFB expre
209 f p38alpha and ERK1/2 or p53 mutations could abolish the inhibitory effects of triptolide on NF-kappa
210 the cancer-associated polymorphism does not abolish the interaction with p73alpha, indicating that o
212 has been used in combination with niacin to abolish the prostaglandin D2-(PGD2)-induced flushing.
213 act in vivo Last, we show that CpaB does not abolish the proteolytic activity of CpaA against human F
214 Ligands binding to the N-terminal domain abolish the spontaneous ionic currents associated with n
215 embrane helices (TM), alphaTM2 and alphaTM4, abolish the stimulation of activity by 18:0/20:4 PC but
216 -C) as mutations within the ORF1p C-C domain abolish the suppressive effect of truncated proteins on
217 cts are DR5-dependent because DR5 deficiency abolished the ability of b-AP15 to enhance TRAIL- or AMG
218 1) applied concurrently with the force field abolished the ability to update subsequent motor command
219 via transcranial magnetic stimulation (TMS) abolished the adaptation of M100 attenuation, while the
220 gainst thrombin-induced EC permeability, but abolished the advanced barrier enhancement phase and sup
221 L-5 neutralization before allergen challenge abolished the allergen-induced rise in circulating eosin
222 siRNA and 1400W, a selective iNOS inhibitor, abolished the ameliorative effects of NaHS on high gluco
223 ckout of the angiotensin subtype 2 receptors abolished the beneficial effects of angiotensin type 1 r
224 L2 knockdown in endothelial cells completely abolished the blood-brain barrier protective effect of r
225 66 in primary human T cells by nucleofection abolished the capacity of ILT3.Fc to inhibit CD4(+) Th c
226 astatic cells by primary glia cell coculture abolished the capacity of metastatic cells to utilize ex
227 ution in transgenic Drosophila (trp(S936A) ) abolished the difference in frequency response between d
231 eta1-integrins or talin in the somitic cells abolished the FN pillars, indicating that FN pillar form
232 eliminated Runx3d expression and completely abolished the generation of CD8(+) single-positive thymo
233 ation with inhibition of sympathetic control abolished the high altitude-induced increase in heart ra
236 athological neovascularization and partially abolished the inhibitory vascular effects of RORalpha de
237 on the miR-150 pairing sequence in FOXD3-AS1 abolished the interactions between FOXD3-AS1 and miR-150
238 h of darkness preceding the NB Cycloheximide abolished the NB up-regulation of PPD1, suggesting that
240 h the GLP-1 receptor antagonist exendin 9-39 abolished the observed difference in glucose tolerance b
241 caveolae by MCD treatment or Cav-3 knockdown abolished the protection against H/R-induced myocytes in
243 gh cholesterol diet-induced liver injury and abolished the protective effect against cholesterol lipo
244 constitutively active Nlrp3(A350V) mutation abolished the protective effect of aPC, demonstrating th
245 nt of fecal material from an untreated mouse abolished the protective effect of microbiota depletion
246 f staphyloxanthin during AirR overproduction abolished the protective phenotype of increased staphylo
249 ions associated with intellectual disability abolished the spacing effect and led neurons to decode d
252 ogical approach to inhibit TNT formation, we abolished the transfer of both alpha-SYN and mitochondri
254 cinerea completely blocked IFS formation and abolished the virulence of DeltaBcsep4 mutants on unwoun
255 e that knockout of the gene encoding PLCzeta abolishes the ability of sperm to induce Ca(2+) oscillat
260 e further demonstrate that depletion of AUF1 abolishes the global interaction of miRNAs and AGO2.
261 ion of the monoubiquitination site in Jmjd1c abolishes the inhibitory effect of Deltex2 on Jmjd1c dem
264 ibition of SRSF1 expression or mTOR activity abolishes the oncogenic properties of MALAT1, suggesting
265 the predominant isomer in the wild type, and abolishes the peak current in electrophysiological measu
267 ingly, removal of introns from a target gene abolishes the requirement for Aquarius, but not HRDE-1,
268 competes with p62 for TRAF6 association and abolishes the sequestration of TRAF6 to cytosolic p62 ag
269 portantly, orchiectomy, but not ovariectomy, abolishes the sex differences in ILC2 development and re
271 mination of phenylalanine residue 211 or 213 abolishes the UQ-dependent activity, produces a leak of
272 x methacholine-induced airway contraction by abolishing the Ca(2+) oscillations, in a manner similar
273 r an amino acid exchange in the stalk region abolishing the N-linked glycosylation site; and 2 varian
276 g the effector-to-memory cell transition and abolished their differentiation into C-X-C chemokine rec
277 in female rats throughout repeated restraint abolished their heightened hypothalamic-pituitary-adrena
281 Moreover, lysosomal destruction or damage abolishes these TFEB-dependent effects in both the cytos
283 Depletion of CD4(+) or CD8(+) T lymphocytes abolished this growth inhibition, identifying it as an i
285 and silencing of CK5 using small hairpin RNA abolished this P4-dependent increase in mammosphere size
286 the innate immunity antibacterial gene Nod2 abolishes this resistance, as Nod2 (-/-) BALB/c mice dev
288 We needed to mutate two lysine residues to abolish trypsin inhibition, suggesting BBI3's mechanism
289 ease, reported by a Syx-based FRET probe, is abolished upon charge neutralization of 5RK (5RK/A).
290 age-derived factors TGF-beta, VEGF and SDF-1 abolished VEGFR1(+) myeloid cell migration and fibroblas
292 births observed in MCPT4-deficient mice was abolished when GBS was deficient in expression of the fi
293 persensitive response (HR) typical of ETI is abolished when the Pseudomonas syringae effector AvrRpt2
298 pha-catenin; the rescue effect is completely abolished with the depletion of alpha-catenin in adipocy
299 duce CPRC cell proliferation in vitro and to abolish xenograft tumor growth in vivo Taken together, o
300 AR upregulation of vesicle replenishment was abolished, yet preNMDAR control of spontaneous release w
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