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1 o cause expression of the spec2a gene in the aboral ectoderm.
2 late and for the activation of spec2a in the aboral ectoderm.
3 rogressive confinement of hyalin mRNA to the aboral ectoderm.
4 purpuratus is expressed specifically in the aboral ectoderm.
5 ween TGFbeta-expressing endodermal cells and aboral ectoderm.
6 e constructs were expressed primarily in the aboral ectoderm.
7 B, which bilaterally separates the oral from aboral ectoderm; (3) the vegetal lateral CB, which bilat
8 , a positive inductive signal to specify the aboral ectoderm and a negative suppressive signal to ina
9 tomeres and is critical for specification of aboral ectoderm and for ectoderm patterning, presumably
10 the CyIIIa gene, expressed in the embryonic aboral ectoderm and on the Endo16 gene, expressed in the
11 ion which accompanies differentiation of the aboral ectoderm, and that a negative regulatory region n
12 SpOtx plays a key role in the activation of aboral ectoderm- and endoderm-specific gene expression a
13 ry studies to be expressed in either oral or aboral ectoderm by 24 h are included, though universally
14 formation is a prerequisite for induction of aboral ectoderm by lithium and for normal ectoderm patte
19 s), which are fated to give rise to oral and aboral ectoderm, developed into polarized embryoids that
20 ur results suggest that SpOtx is involved in aboral ectoderm differentiation by activating aboral ect
24 w that SpGsc is a repressor that antagonizes aboral ectoderm fate specification and promotes oral ect
26 on factor SpOtx is required for endoderm and aboral ectoderm formation during sea urchin embryogenesi
27 not overcome the inhibition of endoderm and aboral ectoderm formation, suggesting that SpOtx functio
31 fic features disappear and expression of the aboral ectoderm marker spec1 encompasses the whole of th
32 aboral ectoderm-specific gene expression and aboral ectoderm morphology, but with C-cadherin present,
34 nism underlying the known dependence of oral-aboral ectoderm polarity on intercellular signaling.
35 cohorts of independently activated oral and aboral ectoderm regulatory genes, and we predict yet uni
36 Strongylocentrotus purpuratus embryogenesis, aboral ectoderm-specific expression of spec2a relies on
37 Coexpressing SpOtx with C-cadherin restored aboral ectoderm-specific gene expression and aboral ecto
38 tein reduced the expression of endoderm- and aboral ectoderm-specific genes and inhibited the formati
39 boral ectoderm differentiation by activating aboral ectoderm-specific genes and that modulating its e
40 markers, although we previously showed that aboral ectoderm-specific genes can be induced by 25 mM l
41 The truncated PDGF receptor-beta caused the aboral ectoderm-specific genes LpS1 and LpC2 to be repre
44 erm, resulted in polarized expression of the aboral ectoderm-specific LpS1 protein, but global expres
46 somere-derived embryoids did not express any aboral ectoderm-specific markers, although we previously
48 is believed to direct the activation of the aboral ectoderm-specific Spec2a gene and more generally
51 pOtx mRNA developed into epithelial balls of aboral ectoderm suggesting that SpOtx redirected nonabor
53 ole is to establish CyIIIa expression in the aboral ectoderm territory as the blastomere founder cell
54 l ectoderm-specific genes in the prospective aboral ectoderm territory, are needed for correct spatia
55 showed that in addition to expression in the aboral ectoderm, the proximal G-string mutation caused e
56 is transcribed exclusively in the embryonic aboral ectoderm, under the control of 2.3 kb cis-regulat
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