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1 motion is that protein target search may be accelerated.
2 ause anthropogenic impacts are pervasive and accelerating.
3 ess in research on health behavior change be accelerated?
4 helial cells, and genetic ablation of Pik3r1 accelerates a mouse model of HER2/neu-driven breast canc
5 A-121431, a small-molecule Nav1.1 inhibitor, accelerates a subsequent VSDIV gating transition to acce
9 in family plays unique and essential role in accelerating actin treadmilling in filamentous actin (F-
10 yndrome (aHUS), was defective in C3bBb decay-accelerating activity (DAA) and factor I cofactor activi
12 evaluated whether decreases in CVD mortality accelerated after 2002 in either NYC or the total US pop
13 s when expressed in Drosophila, the mutation accelerates aggregation in vitro, and the mutant prion-l
14 glucose activates protein kinase A (PKA) to accelerate aging by inhibiting transcription factors Msn
17 heet microscope using propagation invariant, accelerating Airy beams that operates both in single- an
22 ipients with antidonor antibodies results in accelerated antibody-mediated rejection (AMR), complemen
24 eceive US Food and Drug Administration (FDA) accelerated approval based on showing an effect in surro
26 ug class, therapeutic area, priority review, accelerated approval, orphan status, near-regulatory dea
28 f-care CD4 testing at the time of diagnosis, accelerated ART initiation, and short message service (S
30 c effect, arterial thrombosis was related to accelerated atherosclerosis in animal models; however, c
34 eous computer that couples CPUs and GPUs, to accelerate BLASTX and BLASTP-basic tools of NCBI-BLAST.
35 bolic pulmonary hypertension (CTEPH) will be accelerated by an animal model that replicates the pheno
36 OPA with AS and ammonium nitrate was greatly accelerated by evaporation of the solution suggesting an
39 INTERPRETATION: National coverage gains were accelerated by important increases among poor and rural
40 e-limiting for deubiquitination and strongly accelerated by mechanical substrate translocation into t
41 reduced anisotropy, with the velocity being accelerated by more than twice compared with that for th
43 fective cell therapies against cancer can be accelerated by the adaptation of tools to rapidly quanti
44 structural similarity, and loss of Tim10 is accelerated by the disruption of conserved disulfide bon
45 in the focal region of one foil are rapidly accelerated by the laser radiation pressure and interact
46 owed that the sweep of this variant could be accelerated by the presence of copy number variation (CN
47 ligands have also proven to be effective for accelerating C(sp(3))-H activation directed by weakly co
48 rynx and kidney cancers, possibly reflecting accelerated cancer progression, etiologic heterogeneity,
49 ens, XBAT35.2 interacts with defense-related Accelerated Cell Death11 (ACD11) in planta and promotes
50 how that apical resection rather transiently accelerates centrosome disassembly as well as the rate o
54 EP approaches and routes of HIV acquisition, accelerating clinical implementation of the most efficac
56 ingly, loss of RP-MDM2 binding significantly accelerated colorectal tumor formation while having no d
57 ropose that phosphorylation of 53BP1 at S380 accelerates complex formation with USP7 and CENPF to reg
58 support from alpha-kallikrein, subsequently accelerates contact activation and is responsible for th
60 lower baseline perfusion was associated with accelerated decline in cognition (global cognition: beta
61 D2-mdx muscles demonstrated an earlier and accelerated decrease in muscle T2 compared with age-matc
62 -onset program and a late-onset program that accelerated degradation after zygotic genome activation.
67 vivo in knock-in mice (DeltaSRM) resulted in accelerated differentiation of nephron progenitors and b
68 dies binding specific epitopes could greatly accelerate discovery of therapeutics as compared to conv
72 transition states on fullerenes is shown to accelerate disfavored enolate addition and exo Diels-Ald
73 s national quality improvement initiative to accelerate door-to-needle (DTN) times, was associated wi
75 cing environment, the RBC-nanogels showed an accelerated drug release profile, which resulted in more
76 improving the efficiency of clinical trials, accelerating drug development, and for regulatory approv
77 gic aging, the fibrosis progression rate was accelerated during perimenopause, as shown using FIB-4 (
78 despread use of 3HP for LTBI treatment could accelerate elimination of TB disease in the United State
80 ates a subsequent VSDIV gating transition to accelerate entry into the slow inactivated state, result
81 ase of fresh class-enzyme leads to a greatly accelerated enzymatic reaction processes without the nee
82 esign to test two hypotheses: whether use of accelerated epirubicin would improve time to tumour recu
83 ubset of genomic regulatory elements showing accelerated evolution between chimpanzees and humans.
84 required to achieve a given export rate and accelerates export for a given concentration of Suc in t
85 s (C' receptor-1 related isoform Y and decay accelerating factor), and an increase in local TUNEL lev
87 brosis; however, heavy episodic drinking may accelerate fibrosis progression and moderate alcohol use
88 ol use was not substantially associated with accelerated fibrosis progression, whereas drinking >14 d
91 ere was widespread concordance of C3 grasses accelerating flowering time and general delays for C4 gr
92 is and similar settings include testing the 'accelerated' form of the approach and experimenting with
93 up of 46 months, the PFS of panitumumab plus accelerated-fractionation RT was not superior to cisplat
94 In conclusion, transplantation of iPSC-NCSCs accelerated functional nerve recovery with the involveme
96 erall composite score compared with placebo, accelerated GE, and was generally safe and well tolerate
98 S) uses genome-wide markers as an attempt to accelerate genetic gain in breeding programs of both ani
100 , whereas those with de novo DSA experienced accelerated graft loss once DSA was detected, reaching a
102 to outweigh known negative effects, however, accelerated growth may also mean more rapid ageing and s
103 od is characterized by an increased risk for accelerated growth of micrometastatic disease and increa
104 ry responses that can also contribute to the accelerated growth of residual and micrometastatic disea
105 nts in GNAS, which were sometimes found with accelerated growth rather than short stature as describe
108 results suggest that this preparation of PRP accelerates healing of cutaneous wounds only as a contro
110 nt modalities to enhance HSC engraftment and accelerate hematopoietic recovery in the elderly populat
113 These results are expected to significantly accelerate Hsp70 drug discovery by providing XIAP as a p
119 xylation of 2,4-dimethoxybenzoic acid (1) is accelerated in parallel to the extent that the carboxyl
120 e of Tr-A from both formulations was greatly accelerated in vivo compared to in vitro using agitated
121 or bleeding by 1.27-8.82-times compared with accelerated infusion alteplase plus parenteral anticoagu
125 ty functional theory (DFT) calculations, the accelerated KMC method is shown to be capable of efficie
126 s and liver metastases we show that ATM loss accelerates Kras-induced carcinogenesis without conferri
129 ity, IL-6 trans-signaling has been linked to accelerated liver regeneration and several chronic infla
132 ic (DNA-damaging) chemotherapy experience an accelerated loss of the ovarian reserve, leading to subf
134 to increase the mobility of this lid greatly accelerates LSD's binding kinetics and selectively dampe
140 sult is a research and development agenda to accelerate malaria elimination and, in the longer term,
141 pendent form of endocytosis was recruited to accelerate membrane retrieval at increased activity and
143 materials shows promise for stabilizing and accelerating methane production in digesters, permitting
144 n enhanced sampling regime, using a Gaussian-accelerated molecular dynamics (GaMD) methodology, which
149 re detected in the plasma of aged senescence-accelerated mouse prone 8 mice, which are known to have
151 In the case of complete graphs, randomness accelerates mutant fixation for all population sizes, an
154 -pyridone ligand that binds to palladium and accelerates non-directed C-H functionalization with aren
156 ndicate that congruent events can trigger an accelerated onset of neural encoding mechanisms supporti
158 ing channelrhodopsins with kinetics that are accelerated or slowed over orders of magnitude, by disco
159 leads to enhanced systemic inflammation and accelerated organ injury in two mouse models of sepsis-i
161 i pathway-based therapeutics and promises to accelerate our search for novel and effective drugs in a
163 identification of centriole components have accelerated our understanding of its assembly, function,
164 rocapsules were evaluated for particle size, accelerated oxidation by Rancimat, and simulation of gas
165 hermore, we show that elevated NOX4 activity accelerates oxidation of NADH and supports increased gly
167 Treg cells or CTLA-4 in this precise window accelerated parasite clearance and generated species-tra
170 tivity in GSK3(S/A) knock-in mice reportedly accelerates peripheral nerve regeneration via increased
172 ial and yeast ID and bacterial AST using the Accelerate Pheno system in the clinical microbiology lab
174 eived in the laboratory were analyzed by the Accelerate Pheno system within 0 to 8 h of growth detect
175 s cross-talk between the two NDK monomers to accelerate phosphorylation-related assembly of RSs and e
176 Genomic selection holds a great promise to accelerate plant breeding via early selection before phe
180 icient reovirus reverse genetics rescue will accelerate production of recombinant reoviruses as candi
182 vention coverage and impact, and may thereby accelerate progress towards the desired endpoint (e.g.,
183 pe was correlated with a significant risk of accelerated progression compared to non-CRF01_AE subtype
185 ogenous R-spondin administration expands and accelerates proliferation of Axin2(+)/Lgr5(-) but not Lg
186 1-SHQ1 deletion cooperates with PTEN loss to accelerate prostate oncogenesis and that loss of compone
187 ha1 (PLDalpha1), both act as GTPase-activity accelerating proteins (GAPs) for the Galpha protein to a
188 and labeled as follows-class 1: persistent, accelerating, rapid growth (5%); class 2: early, nonpers
190 xpression datasets are being generated at an accelerating rate, but can be complex to visualize.
191 systems provide improved reaction safety and accelerated reaction kinetics, and have synthesised seve
192 l and that they can induce immune tolerance, accelerate recovery from AKI, and promote functional imp
195 al. focuses attention on mutations in human accelerated regions (HARs), a subset of genomic regulato
197 The mission of CGD is to facilitate and accelerate research into Candida pathogenesis and biolog
199 e and time, where refrigeration temperatures accelerated RS formation and total crystallinity more th
200 uch increased cumulus cell expansion, and an accelerated severance of cytoplasmic projections between
201 oils was investigated for five months, under accelerated shelf-life, compared to the synthetic antiox
203 ted land use change are the primary cause of accelerated soil erosion, which has substantial implicat
204 k the Mount Takahe eruptions to the onset of accelerated Southern Hemisphere deglaciation approximate
205 ement of neuronal oscillations in processing accelerated speech also relates to their scale-free ampl
207 of polyunsaturated phosphatidylcholine to ER accelerated SREBP-1c processing through a mechanism that
209 bility of dry formulations during ambient or accelerated storage and in fortified fluid skim milk sto
211 ingly opposed yet synergistically combine to accelerate surface reaction kinetics by several orders o
213 phenotypes of hyperaccuracy and (for D215L) accelerated TC dissociation from reconstituted PICs.
214 ities, regulators, and other stakeholders to accelerate the adoption of innovative technologies and p
217 igands have been identified that can greatly accelerate the C-H alkenylation of O-, S-, and N-heteroa
218 coordinate to the metal center of Cp*RhCl to accelerate the cleavage of the C-H bond of N-pentafluoro
219 agnet was fixed on the back of the sensor to accelerate the cleavage of the magnetic nanobeads-peptid
220 dations provided a high-level view of how to accelerate the conversion of new scientific discoveries
221 As novel therapies are being developed to accelerate the decay of the latent HIV reservoir, it wil
222 will interrupt tuberculosis transmission and accelerate the decline in tuberculosis incidence and mor
223 y centers and commercial partners, which can accelerate the development of truly transformative drugs
226 spiring novel approaches to recapitulate and accelerate the events that give rise to potent bNAb in v
227 h was used to explore the chemical space and accelerate the investigation of key structure-activity r
229 y 200 systematically designed experiments to accelerate the selection of ideal reaction conditions an
230 Collectively, these innovations are helping accelerate the selection of the next generation of crops
233 w mechanisms of immunological disease and to accelerate the translation of these insights into therap
234 and significantly slowed the activation but accelerated the deactivation of NsVBa, whereas the local
235 ication tests such as PCR have significantly accelerated the detection of specific bacteria but gener
236 d screening of small-molecule libraries have accelerated the discovery of chemical probes for studyin
237 genome-wide association studies (GWAS) have accelerated the discovery of genes contributing to glauc
239 ing endogenous neuraminidase activity, which accelerated the molecular aging and clearance of intesti
241 cal mechanical loading and interstitial flow accelerated the overall corrosion rate, leading to loss
243 showed that a high calcium diet dramatically accelerated the progression of prostate intraepithelial
245 o vanadium(V) varying from 0 to 1, phosphate accelerated the reduction kinetics of V10 and V4 and enh
247 e of a general base catalyst and selectively accelerates the cyclizations of 4-allen-1-ols into one p
248 hat CsgB, in the presence of surfactant/LPS, accelerates the fibrillation rate of CsgA by circumventi
251 ntation of adipose-derived stem cells (ASCs) accelerates the process of acid burn wound-healing.
252 VWD type 2A Gly1629Glu mutation drastically accelerates the proteolytic cleavage activity, even in t
254 enhances exposure to key parasite antigens, accelerating the development of protective acquired immu
255 al conductivity minimization and potentially accelerating the engineering of next-generation thermoel
256 erence assembly will serve as a resource for accelerating the genome-assisted improvement of modern w
261 is mode, DRILL removes larger droplets while accelerating the remainder of the ESI plume, producing a
262 ur assays serve as an important platform for accelerating the validation of small molecules that targ
263 ailability of recombinant food allergens can accelerate their structural analysis and benefit specifi
267 nsing (CS) reconstruction, it is possible to accelerate these scans while re- taining key spectral in
270 rsion LA-ICPMS setup was employed, providing accelerated throughput and high sensitivity and permitti
273 elivery, directed stem cell differentiation, accelerated tissue formation, effective vaccination, and
274 ecimen digitization have taken root and have accelerated traditional taxonomic studies as well as dis
277 Rapid identification of this pathogen may accelerate treatment and reduce mortality in the event o
279 circulating microparticles (MPs), supported accelerated tumor growth which was halted by PMP transfu
280 f1 haploinsufficiency in hematopoietic cells accelerated tumor onset and increased levels of tumor-in
281 Correspondingly, engineered deletion of Fes accelerated tumor progression in a BRAFV600E-driven mous
284 ate epithelial homeostasis nor significantly accelerates tumor initiation or progression in the prost
285 eficient mice, NKG2D-sufficient mice display accelerated tumour growth associated with, an increased
286 ted by Craf kinase activity, and effectively accelerates tumour progression when activated in advance
289 s carnitine synthesis and tissue uptake, and accelerates urinary carnitine excretion, although the im
291 y short pulses of light ("night-break" [NB]) accelerates wheat flowering, suggesting that the duratio
292 chanism and proved that Rb(+) deocclusion is accelerated when Na(+) binds to an allosteric, nonspecif
293 transcriptional enhancers were convergently accelerated, whereas enhancers active outside the eye we
295 e portable alcohol detection system has been accelerated with the advent of emerging miniaturization
296 nsion of the M n+1AX n design space has been accelerated with the recent discovery of several solid s
297 lized proresolving mediators of inflammation accelerate wound healing by preventing chronic inflammat
298 ite being short-lived, transplanted ASCs can accelerate wound-healing and reduce hair loss in acid-bu
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