ライフサイエンスコーパス: accelerated atherosclerosis

1 eriodontal disease, upregulation of TLRs, or accelerated atherosclerosis.

2 emia are important risk factors for diabetes-accelerated atherosclerosis.

3 reated the gld.apoE(-/-) mouse as a model of accelerated atherosclerosis.

4 iency led to decreased titers of T15/EO6 and accelerated atherosclerosis.

5 and ApoE-/-OPN-/- mice developed less Ang II-accelerated atherosclerosis.

6 olesterolemia and diabetes, is implicated in accelerated atherosclerosis.

7 cle cells and lesion progression in diabetes-accelerated atherosclerosis.

8 rom retinopathy, nephropathy, neuropathy and accelerated atherosclerosis.

9 n autoimmunity-associated diseases that have accelerated atherosclerosis.

10 ivation in premenopausal females, leading to accelerated atherosclerosis.

11 d chronic hyperglycemia, which significantly accelerated atherosclerosis.

12 In this sense, transplants suffered from accelerated atherosclerosis.

13 and angiogenesis in an experimental model of accelerated atherosclerosis.

14 3alpha in the development and progression of accelerated atherosclerosis.

15 ted chemokine receptors in a model of injury-accelerated atherosclerosis.

16 nked to cardiovascular disease, possibly via accelerated atherosclerosis.

17 ury that leads to neointimal hyperplasia and accelerated atherosclerosis.

18 in clinical and basic aspects of SLE-driven accelerated atherosclerosis.

19 tein levels, high blood monocyte counts, and accelerated atherosclerosis.

20 - with implications for lupus nephritis and accelerated atherosclerosis.

21 , these subjects had no clinical evidence of accelerated atherosclerosis.

22 ter treatment and include cardiomyopathy and accelerated atherosclerosis.

23 drive increased cardiovascular risk through accelerated atherosclerosis.

24 s nephritis, as well as diminish the risk of accelerated atherosclerosis.

25 cular inflammation, intimal hyperplasia, and accelerated atherosclerosis.

26 e these are all independent risk factors for accelerated atherosclerosis.

27 eversed the myeloproliferative disorder, and accelerated atherosclerosis.

28 associated with reduced NO availability and accelerated atherosclerosis.

29 n of these populations with leukocytosis and accelerated atherosclerosis.

30 tes inflammation, TLR4 hypersensitivity, and accelerated atherosclerosis.

31 curs at an average age of 14.6 years from an accelerated atherosclerosis.

32 crease in whole-body cholesterol burden, and accelerated atherosclerosis.

33 riggered by type I IFNs, which might promote accelerated atherosclerosis.

34 with systemic lupus erythematosus (SLE) have accelerated atherosclerosis.

35 stemic inflammation, contributes to pathogen-accelerated atherosclerosis.

36 ducible nitric oxide synthase expression and accelerated atherosclerosis.

37 disease concomitantly prevents P gingivalis-accelerated atherosclerosis.

38 ts with systemic lupus erythematosus exhibit accelerated atherosclerosis, a chronic inflammatory dise

39 In a model of accelerated atherosclerosis after arterial injury in apo

40 pendently associated with the development of accelerated atherosclerosis among otherwise healthy men

41 Type 2 diabetes mellitus is associated with accelerated atherosclerosis and a high rate of arterial

42 duced heart disease (RIHD), characterized by accelerated atherosclerosis and adverse tissue remodelin

43 Fas ligand and apolipoprotein E and exhibit accelerated atherosclerosis and aggravated lupus-like fe

44 or leukocyte-derived OPN in mediating Ang II-accelerated atherosclerosis and aneurysm formation.

45 elucidate mechanisms of uPA/uPAR/plasminogen-accelerated atherosclerosis and aneurysm formation.

46 s and implicate specific pathways in uPA/Plg-accelerated atherosclerosis and aneurysmal disease.

47 To test whether accelerated atherosclerosis and aortic aneurysms were du

48 uPA-accelerated atherosclerosis and aortic dilation are larg

49 nsulin-resistant states are characterized by accelerated atherosclerosis and are associated with incr

50 by strain and by diet group, for features of accelerated atherosclerosis and autoimmunity.

51 The accelerated atherosclerosis and cardiovascular disease i

52 ersus hyperlipidemia as culprits in diabetes-accelerated atherosclerosis and cardiovascular disease,

53 eNOS) double knockout (DKO) mice demonstrate accelerated atherosclerosis and develop abdominal aortic

54 traordinarily high levels of cholesterol and accelerated atherosclerosis and die prematurely of myoca

55 In particular, accelerated atherosclerosis and dilated cardiomyopathy,

56 ong youth were identified that predispose to accelerated atherosclerosis and early cardiovascular dis

57 II moderate-risk conditions associated with accelerated atherosclerosis and early CVD and (2) positi

58 s, Abca1(-/-)Abcg1(-/-) BM recipients showed accelerated atherosclerosis and extensive infiltration o

59 ough these changes may increase the risk for accelerated atherosclerosis and fatal myocardial infarct

60 proves, new recognized complications such as accelerated atherosclerosis and hypertension emerge as m

61 purpose was to investigate the mechanisms of accelerated atherosclerosis and identified vascular auto

62 Severe HHcy accelerated atherosclerosis and inflammatory monocyte/ma

63 dyslipoproteinemia, hyperglycemia, and hence accelerated atherosclerosis and microvascular disease in

64 Although the accelerated atherosclerosis and premature aging of the c

65 tosus (SLE) is independently associated with accelerated atherosclerosis and premature arterial stiff

66 est that these children might be at risk for accelerated atherosclerosis and premature cardiovascular

67 HHcy accelerated atherosclerosis and promoted Ly6C(high) infl

68 These results indicate that accelerated atherosclerosis and renal inflammation in SL

69 d chronic inflammation and its consequences (accelerated atherosclerosis and second cancer).

70 Diabetes causes accelerated atherosclerosis and subsequent cardiovascula

71 ncy virus (HIV) infection is associated with accelerated atherosclerosis and vasculopathy, although t

72 include pulmonary and systemic inflammation, accelerated atherosclerosis, and altered cardiac autonom

73 osis and aneurysm formation, vasculitis, and accelerated atherosclerosis, and might be caused directl

74 ently develop tendon and tuberous xanthomas, accelerated atherosclerosis, and premature coronary arte

75 a and develop tendon and tuberous xanthomas, accelerated atherosclerosis, and premature coronary arte

76 , and develop tendon and tuberous xanthomas, accelerated atherosclerosis, and premature coronary arte

77 s and develop tendon and tuberous xanthomas, accelerated atherosclerosis, and premature coronary arte

78 lations between increased Plg activation and accelerated atherosclerosis are reported in several huma

79 cute thrombosis, neointimal hyperplasia, and accelerated atherosclerosis are the 3 mechanisms that le

80 In a model of accelerated atherosclerosis associated with diabetes in

81 Aged WT arteries developed accelerated atherosclerosis associated with enhanced TNF

82 herefore, be a potential method for treating accelerated atherosclerosis associated with transplantat

83 Antibody deficiency significantly accelerated atherosclerosis at both the aortic root and

84 the endothelial cells caused dysfunction and accelerated atherosclerosis because of loss of insulin-s

85 metformin abated the progression of diabetes-accelerated atherosclerosis by inhibiting mitochondrial

86 , including hypertriglyceridemia and severe, accelerated atherosclerosis can be reproducibly induced

87 correlations linking diabetes mellitus with accelerated atherosclerosis, cardiomyopathy, and increas

88 A unique form of accelerated atherosclerosis, CAV remains the leading cau

89 ivation in a model of angiotensin II (AngII)-accelerated atherosclerosis, characterized by increased

90 ed with Ldlr-/-Npc1-/- macrophages exhibited accelerated atherosclerosis despite lower serum choleste

91 N-acetylcysteine or ezetimibe, inhibited the accelerated atherosclerosis development.

92 littermate controls, uPA-transgenic mice had accelerated atherosclerosis, dilated aortic roots, occlu

93 ase (ESRD), DM is associated with blindness, accelerated atherosclerosis, dyslipidemia, cardio- and c

94 We found that CXCL16-/-/LDLR-/- mice have accelerated atherosclerosis, enhanced macrophage recruit

95 s in people with HIV and could contribute to accelerated atherosclerosis, especially of coronary lesi

96 ies examining mechanisms underlying diabetes-accelerated atherosclerosis have been limited by the lac

97 lammatory high-density lipoprotein (HDL) and accelerated atherosclerosis have been reported in patien

98 ibute to the development of hypertension and accelerated atherosclerosis, highlighting vitamin D repl

99 c effect, arterial thrombosis was related to accelerated atherosclerosis in animal models; however, c

100 C. pneumoniae infection markedly accelerated atherosclerosis in ApoE-deficient mice that

101 nts associated with Porphyromonas gingivalis-accelerated atherosclerosis in apolipoprotein E knockout

102 Accelerated atherosclerosis in APS patients was found as

103 herapeutic implications for dyslipidemia and accelerated atherosclerosis in diabetes and age-related

104 that promote an inflammatory environment and accelerated atherosclerosis in diabetes are poorly under

105 r receptor is involved in the development of accelerated atherosclerosis in diabetes, and identify th

106 aortic smooth muscle cells may contribute to accelerated atherosclerosis in diabetes.

107 id-selective deletion of ACSL1 also prevents accelerated atherosclerosis in diabetic mice without aff

108 ed vascular hyperpermeability and suppressed accelerated atherosclerosis in diabetic rodents.

109 glucose conditions provides a mechanism for accelerated atherosclerosis in diabetics.

110 of coronary heart disease in humans and with accelerated atherosclerosis in mice.

111 , abnormal glucose and lipid metabolism, and accelerated atherosclerosis in nontransplant patients.

112 Accelerated atherosclerosis in patients with diabetes is

113 t an important role for endogenous Ang II in accelerated atherosclerosis in renal dysfunction and off

114 present the first small animal model showing accelerated atherosclerosis in response to hyperglycemia

115 ation and autoimmunity in the development of accelerated atherosclerosis in SLE.

116 e management of traditional risk factors for accelerated atherosclerosis in systemic lupus erythemato

117 that chronic systemic inflammation promotes accelerated atherosclerosis in these patients, the mecha

118 advantage of a new porcine model of diabetes-accelerated atherosclerosis, in which diabetic animals a

119 s of cardiovascular events was attributed to accelerated atherosclerosis, inadequate control of blood

120 ts with systemic lupus erythematosus develop accelerated atherosclerosis independent of traditional r

121 es have supported a causal role for Lp(a) in accelerated atherosclerosis, independent of other risk f

122 opportunities to correct dyslipoproteinemia, accelerated atherosclerosis, insulin resistance, and oth

123 Accelerated atherosclerosis is a hallmark of chronic kid

124 Accelerated atherosclerosis is a major cause of morbidit

125 Accelerated atherosclerosis is an important cause of mor

126 This predisposition to accelerated atherosclerosis is genetically determined bu

127 ed cardiovascular and pulmonary involvement, accelerated atherosclerosis is of increasing concern in

128 activation and the development of nephritis, accelerated atherosclerosis is, instead, related to comp

129 system disorder causes failure to thrive and accelerated atherosclerosis leading to early death.

130 renal failure and nerve damage, and diabetes-accelerated atherosclerosis leads to increased risk of m

131 y lipoprotein cholesterol, hypertension, and accelerated atherosclerosis) may be responsible for the

132 Patients with APS are at increased risk for accelerated atherosclerosis, myocardial infarction, stro

133 ronic allogeneic stimulation participates to accelerated atherosclerosis observed after transplantati

134 ion of circulating monocytes, leading to the accelerated atherosclerosis observed in diabetics.

135 ic plaques could provide a mechanism for the accelerated atherosclerosis observed in patients with RA

136 atherosclerosis is subclinical, dramatically accelerated atherosclerosis occurs in some pediatric dis

137 ansion, which prevented the myelopoiesis and accelerated atherosclerosis of ApoE(-/-) mice transplant

138 ity by this mechanism may partly explain the accelerated atherosclerosis of diabetes.

139 over disease induction, we demonstrated the accelerated atherosclerosis of mature diabetic Akita mic

140 Arteriopathy, sometimes termed accelerated atherosclerosis, often impairs transplants.

141 clude that LDLR-/-; Tg(apoB+/+) mice exhibit accelerated atherosclerosis on a chow diet and thus prov

142 holesterol sterols, which is associated with accelerated atherosclerosis, premature coronary artery d

143 atients with Kawasaki disease are at risk of accelerated atherosclerosis remains controversial, but t

144 Hypertension is not required for the accelerated atherosclerosis seen in apoE/eNOS DKO animal

145 lue in elucidating mechanisms underlying the accelerated atherosclerosis seen in human diabetic indiv

146 ls may be an independent risk factor for the accelerated atherosclerosis seen in primary hypothyroidi

147 that inhibits the neointimal hyperplasia and accelerated atherosclerosis that are at the root of most

148 idence that renal transplant recipients have accelerated atherosclerosis that is manifest by increase

149 ts the neointimal hyperplasia and subsequent accelerated atherosclerosis that lead to human bypass-gr

150 sly shown, using a porcine model of diabetes-accelerated atherosclerosis, that diabetes leads to an i

151 ouse model of disturbed flow that results in accelerated atherosclerosis to identify novel mechanosen

152 1 and 2 diabetes, conditions associated with accelerated atherosclerosis, to inflammation.

153 at normal mice were deficient in a gene that accelerated atherosclerosis with diabetes.

154 or 10 mg/kg) substantially attenuated AngII-accelerated atherosclerosis without altering blood press