ライフサイエンスコーパス: accelerating

1 ion is low and loss-of-function benefits are accelerating.

2 ause anthropogenic impacts are pervasive and accelerating.

3 more than a gigaelectronvolt of energy gain, accelerating a trailing positron bunch in a plasma is mu

4 cause of multiple proteinopathies due to the accelerating accumulation of abnormal proteins including

5 rmation by promoting actin nucleation and by accelerating actin filament elongation together with pro

6 esions from gripping to slipping and further accelerating actin flow in the prospective cell rear, re

7 in family plays unique and essential role in accelerating actin treadmilling in filamentous actin (F-

8 pical EPO-containing gel, can potentiate the accelerating action of EPO on the healing of the burn in

9 sensitivity of temperature dependence while accelerating activation time courses.

10 yndrome (aHUS), was defective in C3bBb decay-accelerating activity (DAA) and factor I cofactor activi

11 FH showed a strong C3bBb decay-accelerating activity, as reported previously, and also

12 lated, result in significantly higher GTPase accelerating activity.

13 Besides accelerating adult FEV1 decline, cigarette smoking also

14 rd, one of the most important approaches for accelerating advances in both termite-targeted and termi

15 aged after a single relatively low TBI dose, accelerating aging-associated thymic involution.

16 ospheric gases down into the interior ocean, accelerating air-sea fluxes, and bring deep nutrients up

17 heet microscope using propagation invariant, accelerating Airy beams that operates both in single- an

18 ry that polyP shows a remarkable efficacy in accelerating amyloid fibril formation.

19 ty is transferred between cells, potentially accelerating and broadening antiviral responses.

20 can lead to unusual properties, such as self-accelerating and ultraselective adsorption.

21 e algorithms may prove useful in augmenting, accelerating, and de-risking experimental deimmunization

22 esearch efforts on BVOC responses to rapidly accelerating anthropogenic impacts at local and regional

23 Importantly, accelerating antigen clearance or simply increasing the

24 We also found that accelerating ASIC desensitization by anion substitution

25 complex by delaying dissociation rather than accelerating association.

26 erstand and manipulate mammalian genomes are accelerating at an astounding pace.

27 s that the expansion rate of the universe is accelerating at present - as was inferred originally fro

28 LDL) receptor, elevating LDL cholesterol and accelerating atherosclerotic heart disease, making it a

29 Although it is clear that limiting or accelerating autophagic flux can result in pathological

30 en, secondary to as-yet unidentified drivers accelerating autophagic pathways, which may underpin the

31 letion attenuates IR-induced AKI, in part by accelerating autophagy with targeted removal of damaged

32 to increasing surface melt directly, thereby accelerating bare-ice exposure and enhancing meltwater r

33 tion of enhancer technology holds promise in accelerating basic neuroscience research and enabling ge

34 The preservation of emittance of the accelerating beam is the next challenge for plasma-based

35 n a normally incident plane wave into a self-accelerating beam on the prescribed parabolic trajectory

36 ression of their spatial spectra, these self-accelerating beams can exhibit a dramatic enhancement of

37 have been demonstrated, such as vortex, self-accelerating, Bessel EBeams etc.

38 APK pathway, which enhances cell survival by accelerating Bim protein turnover.

39 t NAP1L1 promotes CSB-mediated remodeling by accelerating both activation and translocation.

40 dditives may offer a new general approach to accelerating Bronsted acid catalysis in solution.

41 m the K-shell electrons of nitrogen into the accelerating bucket.

42 pic coronavirus-induced encephalomyelitis by accelerating but not enhancing the induction of IFN-alph

43 ligands have also proven to be effective for accelerating C(sp(3))-H activation directed by weakly co

44 passage through the G1 restriction point and accelerating cancer cell proliferation.

45 llosterically realigns active-site residues, accelerating catalysis.

46 ical for understanding surface chemistry and accelerating catalyst selection.

47 drogen responses through AR, maintaining and accelerating cell proliferation through AKT activation,

48 Continued and accelerating change in the thermal environment places an

49 ely correlated, offering a valuable tool for accelerating characterization.

50 er-plasma accelerators (LPAs) are capable of accelerating charged particles to very high energies in

51 f marine populations to persist and adapt to accelerating climate change.

52 logical impacts of this industry relative to accelerating climate changes are poorly characterized.

53 EP approaches and routes of HIV acquisition, accelerating clinical implementation of the most efficac

54 ls (PFTs) are gaining traction as a means of accelerating clinical translation.

55 solution or when localized as nanoparticles, accelerating clotting at 10-200 fold lower concentration

56 safe for use in humans and are effective for accelerating cocaine metabolism.

57 that Crn1 enhances Cof1-mediated severing by accelerating Cof1 binding to actin filament sides.

58 tia and demonstration that it is a key event accelerating cognitive or functional decline would infor

59 d as a hardware-aware parallel framework for accelerating computational hotspots within the hmmsearch

60 or maintaining normal cone-driven vision and accelerating cone dark adaptation.

61 nces cross-bridge formation at long SL while accelerating cross-bridge detachment and relaxation at s

62 drome; multiple cellular abnormalities cause accelerating cycles of inflammation, cellular damage, an

63 near kinetics that were unaffected by either accelerating DAT internalization or binding a high-affin

64 viral vector for siRNA delivery to DCs, thus accelerating DC-based therapies with siRNA.

65 elerating protein (GAP) activity, ultimately accelerating deactivation of G protein signaling.

66 late G protein-coupled receptor signaling by accelerating deactivation of Gi/o alpha-subunits, severa

67 as probably contributed to a substantial and accelerating decline in conceptions in women younger tha

68 ntinued biodiversity loss would result in an accelerating decline in forest productivity worldwide.

69 verexpression of DISC1 was accompanied by an accelerating decline rate of BACE1, and was blocked by t

70 id advances in modern electronics place ever-accelerating demands on innovation towards more robust a

71 or phosphorylation, Ca(2+)had a small effect accelerating dephosphorylation and minimally affected AT

72 this field is particularly timely given the accelerating discovery and characterization of exoplanet

73 s resulting in reduced genetic variation are accelerating disease emergence.

74 Interdependency within the triad fuels an accelerating disease progression that culminates in fail

75 ncrease stress on dystrophic fibers, thereby accelerating disease progression.

76 influenced by lung compliance, albeit while accelerating disease progression.

77 NKX3.1 acts by accelerating DNA repair after androgen-induced transcrip

78 attenuates radiation-induced bone damage by accelerating DNA repair in osteoblasts.

79 cell types that make up the brain is rapidly accelerating, driven in particular by recent advances in

80 improving the efficiency of clinical trials, accelerating drug development, and for regulatory approv

81 Biomarkers play an essential role in accelerating drug development.

82 is important for understanding diseases and accelerating drug discovery.

83 iple channels (8.6mm) were more efficient at accelerating drug release than longer channels (18.2mm)

84 rts of the public health response to rapidly accelerating drug resistance in the region.

85 reduced relative fibrous cap areas, whereas accelerating DSB repair increased cap area and VSMC cont

86 ce for 3'-first pore entry of the duplex and accelerating duplex unzipping, all manifestations of an

87 income settings, could promote bacteremia by accelerating early phase bacterial growth prior to the i

88 ented in this way, the catalyst has a strong accelerating effect at concentrations 40-400 times lower

89 The remarkable accelerating effect of 1,2,3-triazolyl substituents on S

90 cite dissolution kinetic rate because of the accelerating effect of carbonic acid.

91 A-based catalysis concept, thanks to the DNA-accelerating effect, can be an effective approach to ach

92 enhance therapeutic development pipelines by accelerating efficiency, maximizing cost-effectiveness,

93 d with the solar wind, producing a bow shock accelerating electrons to energies of tens of kilovolts.

94 inistration with the triple-drug regimen for accelerating elimination of lymphatic filariasis in diff

95 uninfected individuals increases the risk of accelerating emergence of drug resistance and losing com

96 ery is a promising experimental strategy for accelerating endothelial cell repopulation of stented bl

97 shock is responsible, at least in part, for accelerating energetic electrons in solar flares.

98 Accelerating Epo production in hepatocytes is one plausi

99 etome that remodels the extracellular milieu accelerating ErbB2-driven mammary tumor progression.

100 exity, expansion and sustainability, and the accelerating evolution of human ultrasociality.

101 ications of increasing mutagenesis rates and accelerating evolution through active mechanisms.

102 of reducing extracellular ATP production or accelerating extracellular ATP clearance.

103 ievirus B (CVB) isolates bind to human decay-accelerating factor (DAF) as well as to the coxsackievir

104 VB3) depends on virus interaction with decay-accelerating factor (DAF), a receptor expressed on the a

105 ment-activation controllers, including decay accelerating factor (DAF), are gaining emphasis as they

106 s (C' receptor-1 related isoform Y and decay accelerating factor), and an increase in local TUNEL lev

107 n mutations in the gene encoding CD55 (decay-accelerating factor), which lead to loss of protein expr

108 tegy allowed CFA to be introduced into decay-accelerating factor, suggesting that viral and human reg

109 ane cofactor protein were swapped into decay-accelerating factor.

110 In the process, the accelerating field is altered--'self-loaded'--so that ab

111 elerator technology as they can sustain high accelerating fields over long distances with high energy

112 been proposed as a technique for generating accelerating fields without transverse forces.

113 nking actin networks to membranes; and (iii) accelerating filament elongation.

114 ause of their nonuniform elasticity, thereby accelerating filament severing.

115 provide empirical evidence that the tail of accelerating fishes can increase propulsive efficiency b

116 ere was widespread concordance of C3 grasses accelerating flowering time and general delays for C4 gr

117 eta-CTFs, and attenuated Abeta generation by accelerating flux through the endosome-lysosome pathway.

118 hich highlights the utility of S. viridis in accelerating functional genomic studies in maize.

119 uidic study investigating the feasibility of accelerating gaseous carbon dioxide (CO2) dissolution in

120 e patterns do not contradict the prospect of accelerating global extinctions but are consistent with

121 By accelerating global mRNA decay, many viruses impair host

122 Species extinctions are accelerating globally, yet the mechanisms that maintain

123 This reverses the effective accelerating gradient, and counter-rotates the accumulat

124 accelerators are dominated by the achievable accelerating gradient.

125 We follow this measurement by demonstrating accelerating gradients of 320+/-17 MeV m(-1).

126 ptical or infrared sources have demonstrated accelerating gradients orders of magnitude above that ac

127 tion sources because of their extremely high accelerating gradients.

128 susceptibility to mycobacterial infection by accelerating granuloma necrosis.

129 The accelerating growth in the corpus of sequencing data tha

130 The accelerating growth may result from increased photolytic

131 2) Gompertz-repopulation using the gradually accelerating growth rate with tumor shrinkage.

132 e in stabilizing mutant Htt mRNA and thereby accelerating HD pathology in the mHtt-p53-Wig1 positive

133 However, the role of cocaine in accelerating HIV associated energy deficit and its impac

134 f anaerobic/aerobic microbial metabolism for accelerating HMW-PAHs removal occurred within sediments

135 ation of females and males are effective for accelerating HPV prevalence reduction.

136 The rate of contraction appears to be accelerating in the most recent survey years, and this h

137 payments linked to high-value health care is accelerating in the United States because of new legisla

138 wel disease has become a global disease with accelerating incidence in newly industrialised countries

139 rophication of estuaries and coastal seas is accelerating, increasing light stress on subtidal marine

140 for subsequent work aimed at reinforcing and accelerating investments toward providing services to ma

141 otein (FRP) detaches OCP1 from the PBS core, accelerating its back-conversion to OCP(O) ; by contrast

142 , which weakens the RsrA-sigma(R) complex by accelerating its dissociation.

143 ith Plk1 increases the stability of 53BP1 by accelerating its interaction with the deubiquitinase USP

144 Methodological breakthroughs are accelerating knowledge of the processes underlying both

145 be powerful tools for adapting behaviour and accelerating learning.

146 cells, increasing the number of stem cells, accelerating Lgr5(+) stem cell proliferation, and up-reg

147 t high OGT activity and c-MYC stabilization, accelerating liver tumorigenesis in agreement with c-MYC

148 galectin-1, dampening antitumor immunity and accelerating malignant progression.

149 This self-accelerating mechanism enables a systematic prediction o

150 the expression of many genes in metazoans by accelerating messenger RNA degradation and inhibiting tr

151 materials shows promise for stabilizing and accelerating methane production in digesters, permitting

152 the concept of a versatile, miniature linear accelerating module, which, by employing laser-excited e

153 gene insulation facilitate this approach by accelerating multi-gene pathway construction and the sta

154 d point to potential mechanistic targets for accelerating myelin clearance and improving demyelinatin

155 partly mobile alpha-helix in its aggregation-accelerating N terminus, and semi-rigid polyproline II h

156 ase activity, though this is insufficient in accelerating neuritic tangle pathology.

157 1) to accelerate filament turnover 6-fold by accelerating nucleotide exchange and 2) to shift the equ

158 l observation of energetically confined self-accelerating optical beams propagating along various con

159 Here, we employ a self-accelerating optical pump wave-packet to demonstrate con

160 Accelerating or retarding DSB repair did not affect athe

161 ating and visualizing functional PAMs toward accelerating our ability to understand and exploit the m

162 nflict: Some suggest that change is gradual, accelerating over time, whereas others indicate that it

163 ment occurs across multiple land uses and is accelerating over time.

164 trained oxide thin films are of interest for accelerating oxide ion conduction in electrochemical dev

165 of the great challenges in medicine, but the accelerating pace of research and early hints of clinica

166 xt mining is increasingly used to manage the accelerating pace of the biomedical literature.

167 enous Pref-1 improved glucose homeostasis by accelerating pancreatic ductal and beta-cell regeneratio

168 ent macrophage proliferation and activation, accelerating parasite clearance and reducing pulmonary i

169 risk allele count (genetic load) exhibits an accelerating pattern of SLE risk, leading us to posit a

170 ay a major role in contemporary evolution by accelerating phenotypic changes in wildlife, including a

171 n 2 d postinfection is mostly ineffective in accelerating plasma VL loss in macaques.

172 The method describes has potential for accelerating point-of-care applications, in that biologi

173 Here, we address the issue of accelerating polymer dielectrics design by extracting le

174 lation, which is widely used to describe the accelerating precursory signals before material failure

175 in decreasing the energetic span, therefore accelerating product formation.

176 Accelerating progress in the fight against tuberculosis

177 e editing approaches and their optimization, accelerating progress in this rapidly-moving field.

178 e located at the N-terminal domain (NTD) and accelerating proteasomal degradation through dynamic eff

179 he plasma membrane and augments their GTPase-accelerating protein (GAP) activity, ultimately accelera

180 moting vascular relaxation due to its GTPase accelerating protein activity toward Galphaq.

181 ha1 (PLDalpha1), both act as GTPase-activity accelerating proteins (GAPs) for the Galpha protein to a

182 faces can act as proton-collecting antennae, accelerating proton uptake by membrane-bound proton tran

183 and labeled as follows-class 1: persistent, accelerating, rapid growth (5%); class 2: early, nonpers

184 The Greenland Ice Sheet is losing mass at an accelerating rate due to increased surface melt and flow

185 a sector of the ice sheet have thinned at an accelerating rate, and several numerical models suggest

186 xpression datasets are being generated at an accelerating rate, but can be complex to visualize.

187 cycle relationships, with high precipitation accelerating rates of C exchange with the atmosphere in

188 nges include species invasions worldwide and accelerating rates of extinction.

189 sis, and projections indicate continuing and accelerating rates of global changes.

190 ributions of Earth's species are changing at accelerating rates, increasingly driven by human-mediate

191 Enzymes enable life by accelerating reaction rates to biological timescales.

192 rates cross bridge binding to actin, thereby accelerating recruitment and increasing the amplitude of

193 These losses are accelerating, reducing Earth's albedo and increasing hea

194 , significantly ameliorating progression and accelerating regression of fibrosis.

195 to 9 months, with motor deficits assessed by accelerating rotarod testing.

196 emonstrated by declining performances on the accelerating Rotarod.

197 We study rapidly accelerating rupture fronts at the onset of frictional m

198 Accelerating Schiff base hydrolysis and subsequent ATR d

199 ta, facilitating their in-depth analysis and accelerating secondary metabolite discovery.

200 secondary colony-forming efficiency, and by accelerating senescence in vitro.

201 ockdown of Rusc2 potentiates Hh signaling by accelerating signaling-induced dissociation of the Sufu-

202 hance coastal resiliency under conditions of accelerating SLR.

203 The physical mechanisms behind accelerating solar and stellar winds are a long-standing

204 onal validation of genes in sorghum, thereby accelerating sorghum breeding.

205 hat PRRSV antagonizes the STAT3 signaling by accelerating STAT3 degradation via the ubiquitin-proteas

206 Terahertz-driven accelerating structures enable high-gradient electron/pr

207 ent electron/proton accelerators with simple accelerating structures, high repetition rates and signi

208 gical profiling in applications ranging from accelerating studies of drug safety and efficacy, to ide

209 of GTP.EF-Tu.tRNA ternary complexes, thereby accelerating substrate turnover for rapid depletion of t

210 Single-cell RNA sequencing is greatly accelerating such research, given its power to provide c

211 inal gene expression and T-cell populations, accelerating T1D onset in non-obese diabetic mice.

212 plitude when they are made in response to an accelerating target than to a decelerating one.

213 echnology and reduced cost of sequencing are accelerating the ability to find enzymes and pathways fo

214 ng granulomatous regions while concomitantly accelerating the accumulation of F4/80(+) and Ly6C/Ly6G(

215 branes can generate a local proton gradient, accelerating the acid-catalyzed formation of hydrazone-b

216 ucial to the selectivity of these processes, accelerating the arylation of an adjacent hydroxy group.

217 , creating a global public health crisis and accelerating the assessment of experimental therapeutics

218 ond from imine to diene while simultaneously accelerating the C-C bond formation.

219 lso stimulates thyroid hormone activation by accelerating the conversion of thyroxine to triiodothyro

220 eding induces nucleation at low temperatures accelerating the crystallization process.

221 ement activation on the host cell surface by accelerating the decay of C3 convertase.

222 of dark-state and light-activated rhodopsin, accelerating the decay of ligand-bound forms.

223 s can be used to guide actuator design, thus accelerating the design process.

224 for further dissecting MARV pathogenesis and accelerating the development of effective medical counte

225 develop anxiety-related psychopathology, for accelerating the development of improved interventions,

226 xpression of naive-associated genes, thereby accelerating the development of memory cells.

227 of-of-concept testing of drugs and vaccines, accelerating the development of novel interventions.

228 rupted in individual patients, significantly accelerating the development of precision medicine.

229 enhances exposure to key parasite antigens, accelerating the development of protective acquired immu

230 provides a potentially efficient solution to accelerating the development of therapeutic approaches i

231 to a native slow-inactivated state, thereby accelerating the development of this state during action

232 Importantly, it opens new avenues for accelerating the discovery of stable, atomically precise

233 at the effects of OP3-4 might be involved in accelerating the early steps of osteogenesis.

234 al conductivity minimization and potentially accelerating the engineering of next-generation thermoel

235 d implement a computer-assisted approach for accelerating the exploration of uncharted effective free

236 rborne particles collide and stick together, accelerating the fallout of volcanic ash and climate-for

237 tatic fermentation method that is capable of accelerating the fermentation of glucose using generic S

238 kage map supplies a base for mapping QTL for accelerating the genetic improvement, and will be also u

239 erence assembly will serve as a resource for accelerating the genome-assisted improvement of modern w

240 protein-coupled receptor (GPCR) pathways by accelerating the GTP hydrolysis on G protein alpha subun

241 GM3-depleting strategies as an approach for accelerating the healing of human diabetic wounds.

242 inhibitors may have clinical applications in accelerating the healing of skin wounds.

243 the collective performance of human groups, accelerating the median solution time by 55.6%.

244 ese survival signals in overdrive and may be accelerating the obesity and diabetes epidemics.

245 Recent experimental advances are accelerating the pace of data collection.

246 ol of candidate structures is attractive for accelerating the pace of materials discovery.

247 ux of immune cells, T cell clusters develop, accelerating the pathology in the salivary glands.

248 Warmer temperatures are accelerating the phenology of organisms around the world

249 ted that this complex acts in sporulation by accelerating the phosphorylation of the response regulat

250 ibiting sea-ice refreezing in the winter and accelerating the pre-melting process in the spring, and

251 Accelerating the prevention of cancer will require a lar

252 r stress is a key methodological determinant accelerating the process of tissue decellularization whi

253 Anthropogenic environmental changes are accelerating the rate of biodiversity loss on Earth.

254 onal BRidges to EXperiments) effort aimed at accelerating the rate of gene function validation.

255 ic arginine to the opposing subunit, greatly accelerating the rate of GTP hydrolysis.

256 pen detection surfaces, and in dense arrays, accelerating the rate of parallel target screening used

257 unique heteroatom activation was capable of accelerating the rate of reaction of SNO-OCT with diazoa

258 lines, generating a better photocatalyst and accelerating the reaction.

259 ntually sequestering the released carbon and accelerating the recovery of the Earth system.

260 In addition to accelerating the recovery of the photoresponse, faster P

261 ached hematin molecules acted as catalyst in accelerating the reduction of silver ions in the presenc

262 rationale for developing strategies aimed at accelerating the reendothelialization process.

263 Climate change is accelerating the release of dissolved organic matter (DO

264 is mode, DRILL removes larger droplets while accelerating the remainder of the ESI plume, producing a

265 activate ADP-ribosylation factors (Arfs) by accelerating the replacement of bound GDP with GTP.

266 toxicity of LC and improve organ function by accelerating the resorption of amyloid deposits.

267 Accelerating the search for functional materials is a ch

268 ommunity in recent years have focused on (i) accelerating the sluggish kinetics of the catalyst at th

269 ntional, special-purpose machines may aid in accelerating the solution of some of the hardest problem

270 the connectome enables cooperative effects, accelerating the spread of cascades.

271 ffect" can provide a mechanical advantage in accelerating the symmetry forbidden disrotatory ring ope

272 o care for all forms of tuberculosis and for accelerating the time to diagnosis by aligning services

273 ts with deficient TGFbeta signaling, thereby accelerating the transformation of normal LSCs to metast

274 ting proteins (GAPs) for Galpha subunits and accelerating the turnoff of G protein signaling.

275 mophore in cones, and second, indirectly, by accelerating the turnover of chromophore in rods, which

276 ur assays serve as an important platform for accelerating the validation of small molecules that targ

277 disturb the magma chamber of a volcano, thus accelerating the volcanic activity.

278 n the wounds of diabetic mice, significantly accelerating the wound healing process and improving the

279 forces very strong meridional winds without accelerating the zonal wind component near the equator.

280 herogenic lipoproteins, particularly LDL, by accelerating their catabolism.

281 onstricted the pool of proliferating NPCs by accelerating their cell cycle exit and differentiation i

282 for CSR junctions, thereby facilitating and accelerating their study.

283 rboxylic acids are kinetically equivalent at accelerating this isomerization.

284 n Bag1/3 and the Hsc70 SBD is sufficient for accelerating this step.

285 ed its thrombolytic efficacy, essentially by accelerating thrombus dissolution and preventing rethrom

286 ay serve as amplification platforms, further accelerating transmission.

287 fter badges, 23% reported open data, with an accelerating trend; 39% reported open data in the first

288 gp41 protomers, and neutralizes the virus by accelerating trimer decay.

289 tissue; supporting angiogenesis in vitro and accelerating tumour growth in vivo.

290 mes, such as the Lorentzian spacetime of our accelerating universe, are more attractive as their pred

291 es describe an operations research agenda to accelerating uptake of HIV treatment initiation.

292 energic stimulation plays a critical role in accelerating ventricular contraction and speeding relaxa

293 by certain baculoviruses could be related to accelerating virus replication and to protecting the vir

294 ng is significantly more pronounced at lower accelerating voltages (120 kV versus 200 kV) in both the

295 an increase in the relative contribution of accelerating waves.

296 s influence development of obesity partly by accelerating weight gain in childhood.

297 ice sheets and glaciers (1.37 +/- 0.09 mm/y, accelerating with 0.03 +/- 0.02 mm/y(2)) are offset by a

298 change in both the science and technology is accelerating with no end in sight, putting pressure on o

299 Most efforts have been focused on accelerating wound reepithelialization and closure.

300 differentiation in human acute wounds, thus accelerating wound repair.