ライフサイエンスコーパス: accessible

1 ns and tumor types, all results are publicly accessible.

2 ual spiritual preferences and practices more accessible.

3 o bites than the other when both are equally accessible.

4 ir evidence, not observed directly, socially accessible.

5 making a portion of closed micropore network accessible.

6 ron-poor products, making these more readily accessible.

7 w-cost, low-environmental impact, and highly accessible.

8 JLB), a procedure that is not always readily accessible.

9 hallenged mouse strains which are not widely accessible.

10 e individually addressable and independently accessible.

11 f lysine, arginine and glutamine are readily accessible.

12 the human body, many of which are not easily accessible.

13 as that on the small subunit remains solvent-accessible.

14 RNA structural bioinformatics, and is freely accessible.

15 mbia, we found that HIVST was acceptable and accessible.

16 ate that single molecules are experimentally accessible.

17 atus (catheterization laboratory immediately accessible 24/7).

18 Readily accessible 3-(2-aminophenyl)-5-hexenyn-3-ols under a one

19 on with cofactors that recognize ncRNAs with accessible 5' or 3' ends and/or increase the availabilit

20 affold was assembled starting from an easily accessible A ring building block by a (4 + 2)-cycloaddit

21 allows for the formation of a deep, solvent-accessible, active-site pocket, which may allow recognit

22 The reduction in freeze time, accessible actuation temperatures, chemical compatibilit

23 ternal beta-sheet backbone, but must involve accessible adaptive configurations to interact with such

24 alyst that is derived in situ from a readily accessible aminophenol compound at ambient temperature,

25 rane based on 30 m(2) of graphene, a readily accessible amount, could provide a heavy-water output co

26 summarized genetic data provides a rapid and accessible analytic strategy that can be undertaken usin

27 expressing either CSP allele, which provide accessible and affordable models suitable to support the

28 with international travel becoming ever more accessible and affordable, the danger of transplantation

29 adgroups, making the headgroups more solvent-accessible and increasing surface hydrophilicity.

30 he latter does not distinguish between water accessible and lipid accessible residues in membrane pro

31 mmPort curated study datasets are seamlessly accessible and ready for analysis, thus enabling innovat

32 tant vaccine targets because they are easily accessible and recognizable by the immune system.

33 anscriptomics and proteomics datasets widely accessible and relatively economical to generate, system

34 and blood NfL concentrations can be used as accessible and reliable pre-clinical HD markers.

35 al protocols, our assembly method is readily accessible and will facilitate the construction of sophi

36 ere, we present a novel method that predicts accessible and, more importantly, inaccessible gene-regu

37 encies are hampered by the lack of adequate, accessible, and affordable diagnostic methods that can e

38 The new index, MALT-IPI, is a simple, accessible, and effective tool to identify MALT lymphoma

39 electrohydrodynamic process provides highly accessible, and electrochemically active surface area an

40 strate that PAH-porphyrin hybrids are easily accessible, and this strategy may allow the incorporatio

41 they can be electrochemically reduced under accessible applied potentials.

42 (2+) binding site and reached into a solvent accessible area.

43 gen bonding energies, and amino acid solvent-accessible areas.

44 ChimeRScope is accessible as a standalone software at or via the Galaxy

45 ating plasma exosomal miR-125a-3p is readily accessible as diagnosis biomarker for early-stage colon

46 agenta, brick-red, and intense red hues were accessible as expressed by CIE-L( *)a( *)b( *) color val

47 Using five quick and accessible assays for measuring honey's cytotoxicity in

48 er-friendly pipelines for data analysis, all accessible at lower cost.

49 models presented here can serve as an easily accessible basis to identify alterations of the innervat

50 chromatin regions (OCRs) are differentially accessible between neurons and non-neurons, and show enr

51 ted in other cohorts, p11 could be an easily accessible biomarker for monitoring the severity of PD,

52 singly recognized as noninvasive and readily accessible biomarker for risk stratification, diagnosis

53 xpression and how this related to clinically accessible biomarkers.

54 Thanks to clinically accessible biopsy samples, high-quality molecular data f

55 Effective, accessible biopsychosocial treatments are needed to mana

56 hma at the molecular level, especially using accessible biospecimens, could greatly enable patient se

57 the generation of humanized ossicles with an accessible BM microenvironment that faithfully recapitul

58 ulticomponent reaction in which four readily accessible building blocks are mixed together to form a

59 twork parameters (within the parameter space accessible by biological materials) either increases the

60 ed on the most active lead compound was made accessible by esterification of the terpenols with comme

61 stance between the dyes is outside the range accessible by FRET.

62 VO2 -TiO2 -VO2 nanorod heterostructures are accessible by modulating the growth conditions.

63 nthetic mimic of antifreeze proteins that is accessible by solution, solid-phase, and recombinant met

64 These include depletion of microbially accessible carbon pools, reductions in microbial biomass

65 th the assembled crystalline order and their accessible catalytic repertoire.

66 , yet remarkably little is known about their accessible chemical and biological functions.

67 a: see text] emissions globally using widely accessible chemical and hydromorphological datasets and

68 diverse modifications thereby expanding the accessible chemical space and reducing synthetic efforts

69 These images demonstrate that accessible cholesterol, as judged by PFO* or ALO-D4 bind

70 etermined by ATAC-seq (assay for transposase-accessible chromatin [ATAC] with high-throughput sequenc

71 ration-insensitive targets are found in more accessible chromatin and are bound at low concentrations

72 of promiscuous RNA polymerase initiation at accessible chromatin and is unlikely to generally play a

73 nt progenitors requires the establishment of accessible chromatin at lineage-specific transcriptional

74 hIP-seq) combined with assay for transposase-accessible chromatin coupled to high-throughput sequenci

75 We generated genome-wide mRNA and accessible chromatin data from adult intestinal epitheli

76 sorders we applied the Assay for Transposase Accessible Chromatin followed by sequencing (ATAC-seq) t

77 Chromosomal accessibility assays can connect accessible chromatin in one cell type to many TFs throug

78 telomere healing, with the formation of more accessible chromatin in the break regions prior to DNA e

79 We here performed global mapping of accessible chromatin in the mouse mammary gland epitheli

80 observed increased transcription and a more accessible chromatin landscape around genes involved in

81 ble chromatin, its binding is biased against accessible chromatin located at promoter regions.

82 ssed and bound to more than one-third of the accessible chromatin regions in EpRas cells treated with

83 ing of cis-elements is often associated with accessible chromatin regions.

84 Assay for Transposase Accessible Chromatin sequencing (ATAC-seq) is a recently

85 encing (DNase-seq) and Assay for Transposase Accessible Chromatin sequencing (ATAC-seq) produce genom

86 t CHD7 is necessary for maintaining an open, accessible chromatin state at the Reln locus.

87 ing combined with bulk assay for transposase-accessible chromatin with high-throughput sequencing (AT

88 ical neurons using the Assay for Transposase-Accessible Chromatin with high-throughput sequencing (AT

89 ned by the local chromatin status, marked by accessible chromatin, H3K4me3-modified nucleosomes, and

90 overed that although GR preferentially binds accessible chromatin, its binding is biased against acce

91 Given that GR almost exclusively binds accessible chromatin, we propose that cell type-specific

92 eta-induced EMT that involves alterations of accessible chromatin, which are partly regulated by Etv4

93 endent eviction, leading to the formation of accessible chromatin.

94 F) chromatin remodeling complex to establish accessible chromatin.

95 sed Bayesian modeling within the universe of accessible chromatin.

96 , high levels of paused RNA polymerases, and accessible chromatin.

97 ed exploration framework is required that is accessible, coherent and user-friendly.

98 cycles via controlled cyclizations of easily accessible common precursors.

99 Development of prevention strategies in accessible community-based venues is a potentially impor

100 d within RNA secondary structures and poorly accessible compared with their corresponding canonical 3

101 EcoCyc (EcoCyc.org) is a freely accessible, comprehensive database that collects and sum

102 brane-distal apex or rotated into a receptor-accessible conformation.

103 ne reason for this is a lack of suitable and accessible data processing tools for the analysis of lar

104 tron Exon Comparison and Evolution) is a web-accessible database that houses intron and exon informat

105 The browser's publicly accessible databases are the backbone of a rich, integra

106 and additional open-source annotations using accessible databases via ANNOVAR.

107 To make the statement practical and accessible, detailed descriptions of statistical methods

108 enabled direct estimation of the fraction of accessible DHSs within individual cells.

109 n reactions generated Z-products from easily accessible diene starting materials bearing a Z-olefin m

110 t alpha-carbonyl bicyclic furans from easily accessible diynones is described.

111 With more than a billion people lacking accessible drinking water, there is a critical need to c

112 interactions involving actively marked DNase accessible elements are enriched both at short (<500 kb)

113 systems use an entatic state for modest yet accessible energetics to modulate chemical function.

114 addition to our ability to identify active, accessible enhancers located in open chromatin regions,

115 Surprisingly, DNase-accessible euchromatin is protected from UV, while lamin

116 Compatible with readily accessible fluorescence microscopes, these easy-to-use m

117 we assess and characterize the influence of accessible focusing parameters, including blockage ratio

118 ors version 1.1, and had at least one lesion accessible for biopsy.

119 e designed, in part, to make their backbones accessible for cleavage.

120 As early human embryos are not accessible for direct study, we considered alternatives

121 uNP growth, the surface of the AuNP is still accessible for electrocatalytic reactions.

122 range of distances that has been previously accessible for experimental distance dependent PCET stud

123 ssociative representations, making them more accessible for ideation even when no ideation is explici

124 e of beta-DG from the ER membrane, making it accessible for importins and nuclear import.

125 are located on the outside of the dodecamer, accessible for interaction with client proteins, and dis

126 s that extend over macroscopic length scales accessible for optical characterization.

127 ause extravascular fragments are not readily accessible for removal, many patients are not rendered f

128 loy nanostructures that were previously only accessible for substrate-confined films.

129 that modulation of the conformational space accessible for the two bonds departing from the central

130 tofluidics to deliver NAAT in a portable and accessible format.

131 g and resulted in an average increase of the accessible fraction to 49 +/- 2%, whereby primarily the

132 nds, and that the range of scaffolds readily accessible from nature is limited.

133 insights about electrocatalysis that are not accessible from single-particle electrochemistry.

134 Novel bridged bicyclic ring systems are accessible from the diol, alpha-ketol or 1,2-dione oxida

135 oneal carcinoma explants express p32 protein accessible from the IP space.

136 inoma of the lung, collaborative efforts and accessible genome-phenome databases have partially eluci

137 Among 50 complex traits with publicly accessible GWAS summary statistics (Ntotal approximately

138 e other hand, protected areas that were more accessible, had sparser vegetation, where human populati

139 fore explored the role of Nrf2 in a uniquely accessible human (mini-) organ: scalp hair follicles.

140 igated the hydration state of the deep, well-accessible hydrophobic S1' specificity pocket of the met

141 m, quinolinium, and isoquinolinium salts are accessible in 1-2 steps from the commercial arenes or ar

142 ey injury and CKD guidelines were reportedly accessible in 52 (45%) and 62 (52%) countries, respectiv

143 cohols and quaternary centers) are often not accessible in a direct fashion, necessitating the strate

144 the microvasculature that was previously not accessible in a noninvasive manner.

145 n be below 1 muM, i.e., conditions typically accessible in drug discovery.

146 n neural progenitor cells were biallelically accessible in embryonic stem cells but premarked with bi

147 usive phase transitions that are not readily accessible in equilibrium.

148 hin immune pathways and regions of chromatin accessible in immune cells that was also represented in

149 ed supramolecular networks are synthetically accessible in large scale and exhibit outstanding mechan

150 e of inflammation in asthma, which is hardly accessible in population studies.

151 neoplasms, malignant cells are often easily accessible in the blood as circulating tumor cells (CTCs

152 N-Methoxy imidazolium salts are accessible in three steps from commercial amines (50-85%

153 roaches based on genomics and other relevant accessible information for use in predicting how a patie

154 preselection of known target compounds, all accessible information is used to describe changes acros

155 icly available resource is to provide easily accessible information to a broad oncology audience, as

156 For externally accessible injuries, a variety of natural and synthetic

157 With an easily accessible interface and instant visual feedback, TeachE

158 osed of well-preserved 2D sheets with highly accessible interlayer macropores, narrowly distributed 7

159 a repository for publishing FAIR (Findable, Accessible, Interoperable and Reusable) Data, Operating

160 to introduce or tune functionality, but the accessible layer combinations are limited by the crystal

161 Using this newly accessible ligand class, nickel-catalyzed enantioselecti

162 , we briefly review some frequently used and accessible mass cytometry data analysis tools, including

163 lms, nanolattices redefine the limits of the accessible material-property space throughout different

164 force spectroscopy (SMFS) is a powerful yet accessible means to characterize mechanical properties o

165 CZ-type quantum memory with 225 individually accessible memory cells in a macroscopic atomic ensemble

166 resulting in a maximization of the amount of accessible metallic nickel in the form of small nanopart

167 We describe a refined and accessible method to non-subjectively, rapidly and repro

168 overview and experimental comparison of all accessible methods that could be used to prevent these s

169 ions decrease after bioconversion, while the accessible micropore size distribution increases, making

170 An easily accessible (minimal synthetic steps) and structurally pl

171 r survival, Drosophila represents a uniquely accessible model for understanding the signaling network

172 As the number and complexity of accessible molecular knot topologies increases, it will

173 nt of urinary 'dipstick' tests to assess non-accessible mucosal immune development and identify early

174 taining two stereogenic centers from readily accessible N,N-disubstituted glycine aryl esters and all

175 Herein, we report a readily accessible N-mercaptoethoxyglycinamide (MEGA) solid-phas

176 nsible for converting plant-based feeds into accessible nutrients.

177 by clinical information, creating a database accessible on a cloud platform and through a controlled-

178 ([(+)-NDI-Delta(3(-*))(CoCp2(+))3]) reveals accessible one-dimensional tubular cavities, and variabl

179 w contains behaviorally relevant information accessible only through active behavior.

180 f the Bloch points, which until now has been accessible only through micromagnetic simulations, and i

181 walls under illumination until now have been accessible only to macroscopic studies and their effects

182 st that prograding deltas attain dynamically accessible optima of flux distributions on their channel

183 c engineering, as it is the largest and most accessible organ, epidermal autografts and tissue-engine

184 extraction (SBE) was applied to quantify the accessible PAH fraction in industrially contaminated soi

185 SBE experiments revealed an accessible PAH fraction of 41 +/- 1% ( summation operato

186 If back-mutation to F427 offers an accessible pathway to increase fitness in rCan, reversio

187 {[LCu(III)]2-(mu-O)2}(2+) are energetically accessible pathways for O-O bond formation.

188 Therapies that target the highly accessible peripheral nerve and muscle system provide a

189 epresent a potentially effective and readily accessible pharmacologic approach to fertility preservat

190 while retaining the structural integrity and accessible porosity of CD-MOF-1 (MOF, metal-organic fram

191 ent disease burden, we identify a clinically accessible potential on-treatment predictor of response

192 When accessible pre-existing microhomologies do not exist, we

193 epidemiologic research, we aim to provide an accessible presentation of TMLE for applied researchers.

194 es, a key characteristic of these RNAs is an accessible, protein-free 5' or 3' end.

195 twork representations for storing physically accessible quantum states.

196 strated doublet ground state and a thermally accessible quartet state.

197 distal enhancers, but random monoallelically accessible (RAMA) elements were enriched at promoters an

198 e reagent in both cases, thus augmenting the accessible range of beta,gamma-diamino esters.

199 CIRCLE-seq provides an accessible, rapid, and comprehensive method for identify

200 binding to promoter regions, which are often accessible regardless of cell type examined.

201 in the conserved noncoding sequence 3 (CNS3)/Accessible region 5 (AR5) region of Foxp3 Like many lncR

202 tion of ATAC-seq to sorted nuclei identifies accessible regions genome-wide.

203 Analyzing TF binding sites in differentially accessible regions identified a MYB-driven regulatory mo

204 By filtering out accessible regions observed in bystander, nonexhausted T

205 The secondary structure and solvent accessible regions of oncomiR-1 reveal that most of its

206 footprint of Pol beta mainly resides within accessible regions of the genome and that these regions

207 Therefore, the ability to identify these accessible regions throughout plant genomes will advance

208 CRISPR/Cas9-assisted deletions of chromatin accessible regions within the Zbtb16 locus in mouse, we

209 It is a web-accessible repository for storing and sharing systems bi

210 stinguish between water accessible and lipid accessible residues in membrane proteins.

211 isrupting protein interactions using solvent-accessible residues, and it can provide additional speci

212 cant improvement of our comprehension of the accessible resolution in TERS is thus critical for a bro

213 SPAC)-specifically the subsample forming the Accessible Resource for Integrated Epigenomics Studies (

214 First, the RNA conformation that presents an accessible rut site promotes pausing of RNA polymerase (

215 ether experts with well-developed and highly accessible schemata that lend themselves to distancing h

216 ols, but a non-invasive, inexpensive, easily accessible screening method could be useful in both clin

217 ng a polymeric ectopic scaffold in a readily accessible site under the skin.

218 We identify a large number of layer-specific accessible sites, and significant association with genes

219 f 0-2.3 mm, which corresponds to the maximum accessible spatial offset of the current instrument.

220 reported, and methods making use of biomass-accessible starting materials are also rare.

221 but junctions with radical units have a new accessible state, a single-unoccupied molecular orbital

222 report on the thermodynamics, kinetics, and accessible states of BTK's kinase domain.

223 We have used sophisticated but accessible statistical methods to reveal that spatial co

224 he micropillars only on totally flat, widely accessible substrate areas with the micropillar's struct

225 One is a publicly accessible superconducting transmon device (www.

226 stal structure-based calculations of solvent-accessible surface area and by hydrogen-deuterium exchan

227 sites and neighboring exchange sites on the accessible surface area define the exchange rate regardl

228 ticular, a 3D RVC-Au sponge provides a large accessible surface area for immobilization of enzyme and

229 The solvent accessible surface area of the K1-K10 structure is 20-25

230 nd structure-based identification of solvent-accessible surface area, the latter does not distinguish

231 pores providing optimal percolative flow and accessible surface area, was synthesized in the presence

232 nearly doubles its conformational space and accessible surface area.

233 f solvent entropy based simply on changes in accessible surface area.

234 extracellular domains but also in the lipid accessible surface of the AMPAR.

235 extracellular domains but also in the lipid-accessible surface of the AMPAR.

236 Wide and accessible surface of the mesh combined with high porosi

237 Using this accessible system to examine the molecular mechanisms of

238 eam of SMAD2/3, as a novel pharmacologically accessible target of our transformed HBECs.

239 confirm that endothelial cells were the only accessible targets for DSAs, which induced the developme

240 able of precise site-selectivity at the most accessible tertiary C-H bonds.

241 contrast of PpIX maps, making concentrations accessible that were not visually apparent.

242 With a broader spectrum of functional groups accessible, the PPA/P2 O5 -driven Friedel-Crafts acylati

243 If replicated, this community and clinic accessible therapy may assist cognitive remediation effo

244 data are important source of information not accessible through average flux measurements.

245 The oxalyl unit, readily accessible through commercially available starting mater

246 the source code and sample data are publicly accessible through the NITRC website.

247 terization of the types of dynamical regimes accessible to a given model.

248 X-ray diffraction images makes the technique accessible to a wider range of scientists.

249 Additionally, V1V2 can be rendered more accessible to Abs via specific mutations, facilitating t

250 promises substantial benefits, but it is not accessible to all students and is rarely implemented ear

251 or nutritional improvement of foods that are accessible to and eaten by many.

252 hniques described in this protocol should be accessible to any general molecular biology laboratory.

253 eb-based python notebook (Jupyter), OMAAT is accessible to anyone without programming experience yet

254 f the HER2 status of lesions that may not be accessible to biopsy and assessment of HER2 heterogeneit

255 emonstrate that novel coordination chemistry accessible to ceCblC-bound cobalamin supports its thiol

256 ipids in the outer leaflets of membranes are accessible to daptomycin.

257 that are observed to be active and thus more accessible to environmental exposures and events related

258 h the DTM; however, this species was largely accessible to exogenously added proteinase K, suggesting

259 istal polymer segments are likely to be more accessible to extended objects such as cell membranes, c

260 e mapped to its transmembrane domain that is accessible to extracellular ZnT8 antibody (ZnT8A).

261 Because only fragments of its habitat are accessible to humans, this endangered salamander's exact

262 e retina as an extension of the diencephalon accessible to in vivo microcopy with spectral-domain opt

263 se Genome Informatics (MGI) and made readily accessible to many types of database searches.

264 iatric diseases; by making thalamic circuits accessible to mechanistic dissection; the mouse has not

265 ulfur-rich core of the trimeric BACE1 TMS is accessible to metal ions, but copper ions did not trigge

266 me pathophysiological mechanisms potentially accessible to nongenetic therapies.

267 cular complexes, including ones that are not accessible to other high-resolution biophysical techniqu

268 edicines that are available, affordable, and accessible to patients.

269 AVR3a indicates that the RxLR motif is well accessible to potential processing enzymes.

270 Recently, experimental systems have become accessible to probe the dynamics of nanofriction.

271 acellular loop L3, showing that it is highly accessible to protein-protein interactions.

272 cription and translation, making nascent RNA accessible to Rho.

273 the heme active site in both morphologies is accessible to small molecules for catalysis.

274 tosolic side of the ER, while BeauIII is not accessible to the corresponding active site for SOAT2 lo

275 y active surface area of electrodes becoming accessible to the ferricyanide reaction after nitrocellu

276 However, these complex data are not easily accessible to the plant research community, leaving most

277 dies in biomedical research more visible and accessible to the scientific community.

278 ed recognition surface of MHC-bound peptides accessible to the TCR contains sufficient structural inf

279 ol of cholesterol in the plasma membrane is "accessible" to binding by a modified version of the cyto

280 glet diradical ground state with a thermally accessible triplet state for this unique bis-superoxide

281 Readily accessible unsaturated organoboron compounds serve as re

282 of ethylene, ENAP1-binding regions are more accessible upon the interaction with EIN2, and more EIN3

283 synthesize or require multisteps are readily accessible using a common set of reaction conditions.

284 ction of bacterial biosynthetic diversity is accessible using this strategy.

285 d catalyst, generated in situ from a readily accessible valine-derived aminophenol and a Z- or an E-g

286 O and LUMO energies, making their population accessible via ECL pathways and leading to the generatio

287 ls for the treatment of cancer, will also be accessible via this strategy.

288 ting Earth-sized planets are observationally accessible via transmission spectroscopy when the planet

289 that experience a large reduction in solvent-accessible volume.

290 rmi velocity in Dirac materials in a readily accessible way for experiments.

291 ly procedure even larger structures could be accessible, which could be useful for applications such

292 itriles, etc., many of which are not readily accessible with alternative methods.

293 ducts bearing two adjacent stereocenters are accessible with high diastereoselectivity and enantiosel

294 cores, and can contain local structures not accessible with l-amino acids.

295 ferences in the major psychoses that are not accessible with other structural magnetic resonance imag

296 rent quantum enhanced optimization protocols accessible with state-of-the-art atomic physics experime

297 human ability to keep information in readily accessible working memory is limited to four items for m

298 of highly substituted oxazoles from readily accessible ynamides in the presence of ytterbium(III) tr

299 lincRNA transcriptome in the experimentally accessible zebrafish model by integrating bioinformatics

300 Strategic selection of low-impact and accessible zones is more cost effective with interconnec