ライフサイエンスコーパス: accessory cell

1 ectly on the T cell, rather than through the accessory cell.

2 ntimate association of developing sperm with accessory cells.

3 ion with signals provided by nonconventional accessory cells.

4 n cocultured with certain class II-deficient accessory cells.

5 s fungoides/Sezary syndrome patients' immune accessory cells.

6 madelta T cells, eliminates the need for any accessory cells.

7 the interaction of T cells with conventional accessory cells.

8 n factors that are missing in vitro, such as accessory cells.

9 cells is dependent on signals emanating from accessory cells.

10 t indirect through potentially contaminating accessory cells.

11 interaction between HCs and relevant tissue accessory cells.

12 the interaction between HCs and endothelium/accessory cells.

13 lls from both groups when removed from their accessory cells.

14 l as B7 costimulatory molecule expression on accessory cells.

15 ed mice is a quantitative defect in adherent accessory cells.

16 othelial cells (ECs) and with various tissue accessory cells.

17 macrophages, but rather appear as transient accessory cells.

18 4(+) T cells as well as IL-12 and IL-18 from accessory cells.

19 vitro with an anti-CD3 Ab in the presence of accessory cells.

20 TLRs and activate dendritic cells and other accessory cells.

21 uced immunosuppressive states of T cells and accessory cells.

22 the role of professional and nonprofessional accessory cells.

23 essful/failed BCR-mediated interactions with accessory cells.

24 2,3-dioxygenase was expressed on background accessory cells.

25 function, in which enterocytes become immune accessory cells.

26 killer cells, gamma delta T cells, and other accessory cells.

27 be important in enterocytes becoming immune accessory cells.

28 lymphocyte proliferation in the presence of accessory cells.

29 tly on engrafting stem cells and not through accessory cells.

30 hat comprises distinct lymphocytic cells and accessory cells.

31 li including cytokines, matrix proteins, and accessory cells.

32 several animal models that HIV infection of accessory cells (ACs) plays an important role in develop

33 However, SP had no effect on the accessory cell activities of DCs.

34 cule expression, and acquisition of enhanced accessory cell activity.

35 eloping oocytes that are embedded in somatic accessory cells and encompassed by two epithelial layers

36 ck of FDC or other LTbeta receptor-dependent accessory cells and found that, in response to nonreplic

37 re induced to proliferate in the presence of accessory cells and HVS14-containing supernatant.

38 d TLR3 activated NK cells indirectly through accessory cells and induced the distinct stimulatory cyt

39 250 microg/mL 5-FU for 1 to 2 hours depleted accessory cells and resulted in a cell population that g

40 Cocultures of accessory cells and T cells from mice given different di

41 t IL-10 inhibits the function of host immune accessory cells and that the direct pathway of alloantig

42 oduce IL-17 was dependent on the presence of accessory cells and the production of IL-6, IL-23, and T

43 ough these chemokines, CLL cells can recruit accessory cells and thereby actively create a supportive

44 cells would be augmented by the presence of accessory cells and/or accessory cell factors.

45 unfractionated splenocytes, suggesting that accessory cells and/or factors produced by them play an

46 kly intervals with immobilized anti-CD3 mAb, accessory cells, and exogenous cytokines, and were analy

47 examined the role of Th1 and Th2 cytokines, accessory cells, and lymphoid organs that are known to b

48 B cells are capable of functioning as accessory cells, and their role in experimental murine s

49 nd (CD154)-expressing T cells, Ag-presenting accessory cells are activated for increased cytokine syn

50 m regulating colocalization of CLL and these accessory cells are largely unknown.

51 that cell contact-dependent signals from the accessory cells are necessary for NK cell activation.

52 itive (B cells) or B7-negative (endothelial) accessory cells, are mediated through the same cis-eleme

53 owever, those studies relied on cell-free or accessory cell-based assay systems that do not accuratel

54 produce IL-2 when challenged with Ag-pulsed accessory cells because of a transcriptional defect.

55 s in the type I IFN response of IAV-infected accessory cells between HLA-C1 and HLA-C2 homozygous sub

56 Th cells are dependent on accessory cell-bound co-stimulatory signals for activati

57 entwined with its microenvironment, in which accessory cells can promote leukemia cell growth and/or

58 ulomas contain increasing numbers of B7-poor accessory cells capable of inducing Th-cell unresponsive

59 indicate that keratinocytes may function as accessory cells competent to prime naive skin-reactive T

60 number and characteristics of accompanying "accessory cells" contained in stem cell allografts.

61 ity, and CCR1 expression on both T cells and accessory cells contributed to GVHD mortality.

62 Ligation of the TCR alone, in the absence of accessory cell costimulation, is sufficient to induce ap

63 iated immunosuppression but resulted from an accessory cell deficiency.

64 secretion from cultured lymph node cells is accessory cell dependent and can be partially blocked by

65 nal allogeneic mixed lymphocyte reaction and accessory-cell dependent mitogen induced proliferation a

66 roved functional in both allo-MLR assays and accessory-cell dependent mitogen proliferation assays.

67 monocytic cell line U937 could only provide accessory cell-dependent costimulatory signals for the g

68 Th cells to study the role of cytokines and accessory cell-dependent costimulatory signals in this p

69 s to proliferate and produce IFN-gamma in an accessory cell-dependent manner and in the absence of ex

70 sults in induction of T cell apoptosis in an accessory cell-dependent manner.

71 posure to HCVcc suggests the existence of an accessory cell-dependent NK cell lytic defect in chronic

72 endent apoptosis reflects altered Ag-driven, accessory cell-dependent signaling and that ineffective

73 s, an IL-2-dependent mechanism observed with accessory cell-dependent T cell mitogens and specific Ag

74 resence or absence of superantigens or other accessory cell-dependent T cell mitogens.

75 tic cell and monocyte activation, as well as accessory cell-dependent T-cell activation.

76 tigen receptor stimulation in the absence of accessory cell-derived costimulatory signals lose the ca

77 r function, either in terms of dependence on accessory cell-derived factors or susceptibility to cell

78 and that these interactions are regulated by accessory cell division proteins such as ZipA, EzrA and

79 evel of NK cell cross-talk and regulation by accessory cells during TLR-mediated activation.

80 ed by the presence of accessory cells and/or accessory cell factors.

81 and T cells as well as from macrophages and accessory cells (follicular dendritic cells and interdig

82 Follicular dendritic cells (FDCs) are potent accessory cells for B cells, but the molecular basis of

83 Dendritic cells are necessary as accessory cells for microbial Ag-mediated Vdelta1 gammad

84 kemic cells, identified in this study as new accessory cells for rhIL-15 trans-presentation.

85 at synovial fibroblasts can also function as accessory cells for T cell activation by superantigens a

86 RA type B synoviocyte lines were potent accessory cells for T cell responses to bacterial supera

87 er monocytes or resting B cells can serve as accessory cells for T cells following activation by anti

88 m RA type B synoviocytes could also serve as accessory cells for T lymphocyte activation.

89 t the idea that macrophages may be essential accessory cells for the generation of class I MHC-restri

90 es, neutrophils, and CD4 T cells to serve as accessory cells for Vgamma9Vdelta2 T cell activation in

91 ng luciferase are cultured with nonmalignant accessory cells (for example, stromal cells) for selecti

92 f patients with acute dengue proliferated if accessory cells from a control donor were present.

93 Alcohol consumption inhibits accessory cell function and Ag-specific T cell responses

94 killer (NK) cells, antigen presentation and accessory cell function by macrophages and dendritic cel

95 familial patient monocytes are defective in accessory cell function for IFN-gamma production.

96 t that alteration of cytokine production and accessory cell function for mitogens and anti-CD3-induce

97 We investigated cytokine production and accessory cell function in human macrophage hybridoma ce

98 either increased parasite burden nor altered accessory cell function independently biased towards Th2

99 ses via inhibition of DC differentiation and accessory cell function through mechanisms that involve

100 ell costimulatory receptors, but synoviocyte accessory cell function was evident even in the absence

101 und migrating lung worms and/or a deficit in accessory cell function within a focus, both of which wo

102 Studies of antibody gene assembly, accessory cell function, post-thymic T cell development,

103 indicating possible differences in T-cell or accessory-cell function.

104 Examination of accessory cell functions associated with resistance to T

105 ggest that such a complex may be critical in accessory cell functions during antigen-specific immune

106 eby providing the functional T cell help and accessory cell functions required for fully competent B

107 bility of interleukin-10 (IL-10) to suppress accessory cell functions required for optimal T-cell act

108 ular adhesion molecule (ICAM)-1 expressed on accessory cells has a key role in antigen presentation.

109 However, just as DCs are crucial accessory cells in generating immune responses, they als

110 ll proliferation induced by CD154-expressing accessory cells in media containing interleukin-4 and -1

111 Additional experiments revealed that accessory cells in peritoneal cell populations were the

112 45RB(high) T cells were exposed to Ag-pulsed accessory cells in serum-free medium for 24 h; cultured

113 t human class II-expressing PMN can serve as accessory cells in superantigen (SAg)-mediated T-cell ac

114 propose that the impaired migration of these accessory cells in the brain may explain the improved cl

115 as interaction with its ligand (FasL) and of accessory cells in the CD4XL model of T cell apoptosis m

116 antigen-presenting cells and IL-12 producing accessory cells in the initiation of cell-mediated immun

117 ing the release of inflammatory mediators by accessory cells in the skin microenvironment.

118 To identify the relevant accessory cells in vivo, we generated bone marrow chimer

119 ollection of factors that can be produced by accessory cells influence Th commitment (e.g., IL-1, PGE

120 s overcome by prestimulation with allogeneic accessory cells instead of mitogen.

121 Multiple myeloma (MM) cell and BM accessory cell interaction promotes MM survival via both

122 Here we show that a CD4+CD3- accessory cell is tightly associated with discrete VCAM-

123 In physiology IL-15 trans-presentation by accessory cells leads to pleiotropic activities, includi

124 od employed here, not only B cells, but also accessory cells (macrophages) or their factors may be li

125 These data show that ICAM-1 on donor lung accessory cells mediates differential effects on the his

126 T cell response proceeded in the absence of accessory cells, MHC class II, beta 2-microglobulin, or

127 ned that TNF-alpha secretion from both donor accessory cells (monocytes/macrophages) and T cells sign

128 prothoracic tarsi and in sensory neurons and accessory cells of long labellar sensilla in the distal

129 Incorporation of MYP into the accessory cells of the ovary and its packaging into yolk

130 te away to occupy a position proximal to the accessory cells of the sense organ.

131 ing is typically performed in the absence of accessory cells of the tumor microenvironment, which can

132 activation state, availability of IL-2, and accessory cell or CD28 costimulator signals.

133 adelta T cells did not depend on specialized accessory cells or Ag processing.

134 enhance hematopoietic recovery by the use of accessory cells or direct intra-bone marrow injection ar

135 aditional form of analysis requires that all accessory cells or their factors be present in saturatin

136 quantitative and qualitative defects in the accessory cell population during acute dengue illness re

137 on of primitive NK progenitors, was a better accessory cell population than irradiated PBMNC, NK were

138 s independently of T cell help and any other accessory cell population.

139 lts in an upregulation of CD40 expression on accessory cell populations at local sites of infection a

140 tion is postulated to result from donor lung accessory cells presenting alloantigens to recipient lym

141 LR2-deficient mice cocultured with wild-type accessory cells produced IFN-gamma at levels comparable

142 not been determined, however, whether these accessory cells provide direct costimulation to the T ce

143 evidence that poly(I:C) acts through diverse accessory cells rather than solely through DCs.

144 Further investigations on accessory cells showed that bone marrow-derived dendriti

145 n upon adenoviral infection was dependent on accessory cells such as dendritic cells and macrophages

146 nstrated that STAT1 signaling in both NK and accessory cells such as dendritic cells was required for

147 in lymphocytes via trans presentation, where accessory cells such as macrophages and dendritic cells

148 onary phenotype depending on the presence of accessory cells such as myeloid DCs, and DC subsets can

149 l induction of T-cell proliferation requires accessory cells, such as primary monocytes or Raji B-lym

150 tigen-specific costimulatory signals through accessory cell surface molecules.

151 Accessory cell-surface molecules involved in the entry o

152 L-25 induces Th2-type cytokine production by accessory cells that are MHC class II(high), CD11c(dull)

153 This defect is partially attributable to accessory cells that are more prevalent in bone marrow.

154 Monocytes were identified as accessory cells that augmented the anti-DV IFN-gamma res

155 therefore, not only recruit T cells but also accessory cells that bear activating Fcgamma receptors (

156 APCs are important accessory cells that modulate T cell responses which ini

157 ugh monocytes have been considered important accessory cells that provide the Ag isopentenyl pyrophos

158 s, and suggest that monocytes participate as accessory cells that sense DV infection and amplify the

159 actions between neoplastic B lymphocytes and accessory cells that shape a supportive microenvironment

160 However, when removed from the influence of accessory cells, the CE of AA CD34+ cells decreased sign

161 ata suggest that the responsiveness of donor accessory cells to LPS may be an important risk factor f

162 re, we demonstrate that the basophil was the accessory cell type required for TH2 induction in respon

163 re, we demonstrate that the basophil was the accessory cell type required for TH2 induction in respon

164 -specific Th17 cells and monocyte/macrophage accessory cells ultimately causes progressive airway obl

165 ctivating receptor NKG2D were upregulated in accessory cells upon adenoviral infection and that block

166 The accessory cell was an adherent cell that could be remove

167 onstrated that a bone marrow-derived ICAM-1+ accessory cell was involved in the generation of some TC

168 e B cell line JY (B7-1+ B7-2+), as source of accessory cells, we could generate distinct Th subsets.

169 Interestingly, multiple accessory cells were implicated, with MDA5 acting primar

170 Resting B cells are incompetent accessory cells whereas activated B cells are capable of

171 egg cell plays a central role in specifying accessory cells, whereas in both gametophytes, companion

172 d occupy positions basal and proximal to the accessory cells which remain in the epithelium.

173 to promote maturation or whether it acts on accessory cells, which in turn affect LC precursors.

174 uggest that the acute granulomas are rich in accessory cells with overall phenotypic configurations t

175 Preincubation of accessory cells with the respective stimuli revealed pot

176 However, interaction of accessory cells with the tumor-initiating cell within th

177 PS1 variants were identical, suggesting that accessory cells within the hippocampal niche expressing