ライフサイエンスコーパス: accrue

1 dose-response relationship as complications accrue.

2 hich no further gains in conduction velocity accrue.

3 ce is determined by the magnitude of fatigue accrued.

4 low-up of 9.4 years, 654 diabetes cases were accrued.

5 Stage 2 follow-up is ongoing and is fully accrued.

6 e cycle and intergenerational effects can be accrued.

7 women) with HCC (n = 21) or LM (n = 20) were accrued.

8 50 cases of primary nonmyeloid cancers were accrued.

9 ed KRAS and 106 with indeterminate KRAS were accrued.

10 ril 2001 to February 2008, 345 patients were accrued.

11 Forty-five patients with PCNSL were accrued.

12 ding of how the calixarenes are assembled be accrued.

13 One hundred and forty-four patients were accrued.

14 satisfying relaxed CS clinical criteria were accrued.

15 ry 2001 and February 2002, 946 patients were accrued.

16 dots, as a result fluorescence quenching was accrued.

17 or score and the number of citations a paper accrues.

18 From September 2001 to September 2003, we accrued 106 patients who had undergone complete gross tu

19 uality-of-life study of whom 2208 (81%) were accrued (1129 patients from trial A and 1079 from trial

20 Patients accrued 116,073 person-years of follow-up.

21 with baseline T-scores of -2.0 or more were accrued (147 allocated exemestane, 153 anastrozole); and

22 icenter FinXX randomized clinical trial that accrued 1500 women in Finland and Sweden between January

23 s: Standard management yielded 9.6 QALYs and accrued $155261 in lifetime costs, while intensive manag

24 a mean follow-up of 9 y, 518 vascular events accrued (171 ischemic strokes, 133 MIs, and 314 vascular

25 intensive management yielded 10.5 QALYs and accrued $176584 in costs.

26 GSK conducted 40 cancer RCTs accruing 19,889 patients and CTG conducted 77 trials enr

27 The algorithm accrued 21,644 subjects (65.83% European American and 34

28 The trial accrued 210 eligible patients (105 randomly assigned to

29 On average, trials accrued 25 to 35 patients over a 2-year period and teste

30 toring board recommend study closure, having accrued 295 patients.

31 Between Aug 28, 2014, and May 18, 2016, we accrued 30 eligible patients and treated them with BAT.

32 The study planned to accrue 324 patients and was powered for a 50% improvemen

33 The study accrued 344 patients from 2008 to 2013.

34 The EHR-based classifications were used to accrue 4,500 bipolar disorder cases and 5,000 controls f

35 ry outcomes for the pilot phase were time to accrue 500 participants and retention; secondary outcome

36 e costliest 5% for glaucoma-related charges (accruing $5810 or more in charges in the first 2 years)

37 with an incremental impact as complications accrued (6.7% 1 complication vs 26.1% >/=3, lowest quint

38 r surgery (n=8,097) without radiotherapy and accrued 60,065 and 81,227 person-years of follow-up, res

39 Forty-four patients were accrued; 60% had stage III to IV disease; median age was

40 Reach Out to Enhance Wellness (RENEW) trial accrued 641 locoregionally staged, long-term (>/= 5 year

41 Of 682 patients accrued, 649 were analyzable for outcomes.

42 rising 41.7% of the sample population) would accrue 81.8% of reductions in premature deaths and 87.1%

43 In all, 410 survivors were accrued (96% female; mean age, 54 years; 75% had breast

44 ic, myocardium identifies which patients may accrue a survival benefit with revascularization versus

45 ber of events and shortens the time taken to accrue a target number of end points in an event-driven

46 Of this total, decreased caregiver costs accrued a $31 406 savings against the direct medical cos

47 medical costs, whereas decreased wage losses accrued a $3978 savings.

48 In contrast, early colectomy with IPAA accrued a discounted lifetime cost of $147,763 per patie

49 Standard medical care accrued a discounted lifetime cost of $236,370 per patie

50 g mortality between treatment arms, 13 (38%) accrued a sample size large enough to find an absolute m

51 , those who had an improvement in EF to >35% accrued a similar relative reduction in mortality with I

52 re, old CD154 (CD40L)-deficient mice did not accrue ABCs, confirming that they arise primarily throug

53 ise from inefficiently repaired lesions will accrue according to absolute time; thus, unless life his

54 the years of follow-up required in order to accrue adequate numbers of cancer cases.

55 show how therapeutic effects may eventually accrue after existing therapeutic ligands bind to these

56 A significant proportion of bone is accrued after adult height is achieved.

57 ppocampal volume trajectories as a marker of accruing Alzheimer disease and vascular pathology in eld

58 ed States government and nvAMD patients have accrued an estimated savings of $9.0 billion and $2.2 bi

59 his or her lifetime, an infected individual accrues an average net present value of $3456 and 3.57 D

60 obese adults in the UK by 2030, consequently accruing an additional 6-8.5 million cases of diabetes,

61 es generally perceive socioeconomic benefits accrue and that community funding structures are prefera

62 itigate the savings that Medicare might have accrued and may perpetuate the fee-for-service payment m

63 of cases of WNV-mediated memory dysfunction accrue annually, the mechanisms responsible for these im

64 ively decrease all losses of crop yield that accrue as a consequence of abiotic stress-induced plant

65 These results indicate that DNA damage accrued as a result of elevated ROS in Foxo3(-/-) mutant

66 We note that biases are accrued as part of the recording process (e.g. species'

67 g-like effect of loss of heterozygosity that accrues as gene conversion and hemizygous deletion expos

68 n, multiple naturally acquired Mc grafts can accrue, as they harbor Mc from their own mothers (matern

69 ging several measurements, with most benefit accrued at 5 to 6 measurements.

70 ontributes to the maintenance of adaptations accrued at NAc MSN synapses during incubation of cocaine

71 erence needs to be maintained to continue to accrue benefit.

72 patients and their matched unrelated donors, accrued between 1995 and 2004.

73 e University of Rochester from using tissues accrued between 1997 and 2005.

74 ology and pT3, pT4, or node-positive disease accrued between 2006 and 2010 to the double-blind random

75 Data were accrued between January 2010 and June 2013.

76 monstrate how low-density fitness advantages accrue by the Janzen-Connell mechanism.

77 achinery to transmit epigenetic information, accrued by past generations, into future generations to

78 we showed that additional ICU time is often accrued by patients after they are deemed ready for disc

79 ssessment in patients enrolled onto actively accruing cancer clinical trials.

80 NK cells to participate in cytotoxicity via accrued CD16-mediated signaling and by increasing serial

81 ssified as historically low- (HLACs) or high-accruing centers (HHACs) based on accrual to 21 RTOG HNC

82 Using these prospectively accrued clinical data, relatively large treatment effect

83 tion of patient-specific parameters from the accruing clinical data, construction of personalized mod

84 re performed in a cohort of 25 prospectively accrued, clinically suspected lung cancer patients befor

85 In all, 98 patients were accrued (cohort A, 12; cohort B, 86).

86 Neurodevelopmental Cohort is a prospectively accrued, community-based sample of 9498 youth who receiv

87 billion years, ancestral complexes that have accrued contemporary components, and rarer metazoan inno

88 Most actively accruing cooperative group clinical trials do not assess

89 ial carbon benefits, it comes at the rapidly accruing cost of woody plant species adapted to the open

90 However, along the way the industry has accrued critics whose accusations have tainted its reput

91 In this article, by analyzing the accrued data in The Cancer Genome Atlas (TCGA), we show

92 Using previously accrued data, with alpha of 0.05 and power 80%, the samp

93 the spectrum of Guillain-Barre syndrome are accruing data for clinical and biological databases to i

94 Moreover, accruing data from the genetic to the physiological impl

95 have experienced financial hardship if they accrued debt, sold or refinanced their home, borrowed mo

96 Animals can accrue direct fitness benefits by accurately classifying

97 s been suggested that model-free value might accrue directly to the preconditioned cue through mediat

98 These benefits could accrue due to larger group sizes in general but also to

99 rs to be related to the magnitude of fatigue accrued during exercise, which may explain the reported

100 ay be determined by the magnitude of fatigue accrued during exercise.

101 positive impacts, allowing repair of damage accrued during exposure to thermal extremes, or negative

102 A previous study correlated changes accrued during mouse adaptation in the VP40 gene of a MA

103 study demonstrates how genetic changes that accrued during mouse adaptation of the Ravn strain of Ma

104 monitor safety and/or efficacy for patients accrued during the expansion phase and to update or conf

105 vation is related to the sleep pressure that accrued during the prior waking period.

106 ding and catalytic behavior, but photodamage accrued during ultraviolet (UV) shadowing steps of sampl

107 low-wave sleep to recover from the "fatigue" accrued during wake, when overall synaptic activity is h

108 mathematically identical across species, and accruing evidence indicates economic-based descriptors o

109 Accruing evidence indicates that production of new oocyt

110 f the primary substrate across the membrane, accruing evidence on significant water transport and eve

111 hes between quiet and loud, midbrain neurons accrue experience to find an efficient code more rapidly

112 Accrued experience with the Boston KPro has demonstrated

113 es in today's oceans, regular echinoids have accrued far less morphological diversity than irregular

114 It also accrues financial value to patients, public and private

115 consistent with the suggestion that females accrue fitness benefits by timing peak energy demands of

116 rivals subsequently mate for longer and thus accrue fitness benefits under increased competition, in

117 Six hundred ninty-nine patients were accrued for a SLNB with an average age 57.1 +/- 12.8 (ra

118 urther reduction in risk of ischaemic stroke accrued for aspirin only versus control from 6-12 weeks,

119 Nevertheless, evidence is accruing for broad, threat-neutral sensory hyperactivity

120 Minor increases in usable DCD kidneys could accrue from increased use of pediatric DCD kidneys and f

121 MSC) studies assume that therapeutic effects accrue from local myocardial effects of engrafted MSCs.

122 t although several fitness benefits probably accrue from multiple mating, logistical constraints on m

123 t in part, to the biological advantages that accrue from recognizing and responding to conspecific vo

124 numerate the significant benefits that would accrue from sequencing a broader range of taxa, as well

125 eport here that these differing observations accrue from stage-specific effects of Hh signaling in th

126 Whether the same benefits accrue from unrelated donors will require further follow

127 ntribution from Canadian forests will likely accrue from wood substitution that reduces fossil fuel-b

128 Ovarian Cancer Association Consortium (data accrued from 1992 to 2010).

129 Data were accrued from 1994 to April 1, 2014.

130 In all, 251 patients were accrued from 1998 to 2002.

131 pain flare after radiotherapy, patients were accrued from 23 Canadian centers from May 30, 2011, to D

132 Data were accrued from 2846 patients who underwent pancreatoduoden

133 cer younger than 50 years were prospectively accrued from 51 hospitals into the Ohio Colorectal Cance

134 f-inhibition, we surveyed enzymological data accrued from a century of experimentation and generated

135 e experimental tools and knowledge that have accrued from a long history of reductionist biology, we

136 an be offset by savings due to reduced costs accrued from a reduction in complication rates and hospi

137 Most of the savings are accrued from lower costs of case management and househol

138 Of 113 patients accrued from March 2011 through November 2012, 42 patien

139 ons, we studied pretreatment tumour biopsies accrued from patients in two studies of neoadjuvant arom

140 e analysis, we sequenced five bladder tumors accrued from patients with muscle-invasive transitional

141 The benefits accrued from presenting corresponding sounds show that c

142 on 10q23 were found to cause 85% of CS when accrued from tertiary academic centers, but prospective

143 Follow-up time accrued from the date of return of the baseline question

144 The principles accrued from the study of the latter Ru carbenes and Mo

145 This regulation likely accrues from a phosphorylation-sensitive nuclear localiz

146 Recent data accruing from frequentist and network meta-analysis have

147 dium handling and the hypertensive response, accruing from the functions of the cytokines that they p

148 ostomes reached a point where they ceased to accrue further mandibular functional disparity before be

149 relatively reduced infectivity and the virus accrued G-->A hypermutations, consistent with APOBEC3 pr

150 In all, 107 patients were accrued: gemcitabine-docetaxel plus placebo (n = 54) and

151 larization of the electromagnetic fields are accrued gradually along an optical path.

152 [SE 0.006] fewer using US EQ-5D scores) and accrued greater hospital costs (UK pound101 [SE pound37]

153 , revealing that strand breaks significantly accrue in HSCs during aging.

154 chanism through which premalignant mutations accrue in HSCs.

155 Thousands of somatic mutations accrue in most human cancers, and their causes are large

156 Although expansions can accrue in non-dividing cells, we also show that cell cyc

157 g unique potential for adaptive mutations to accrue in one copy, without abolishing the endogenous ro

158 cular disorders, similar benefits might also accrue in patients with chronic kidney disease.

159 rdial ischemic injury, Ly-6C(high) monocytes accrue in response to a brief C-C chemokine ligand 2 bur

160 Linear growth deficits accrue in the first 1000 d of life.

161 on ineffective and allowing new mutations to accrue in the genome.

162 Th17 cells accrue in the intestine in response to particular microb

163 dozen layers, excess positive sites begin to accrue in the multilayer.

164 types of putative smoke taint compounds that accrue in wines.

165 crobial evolution, but genome sequences have accrued in a haphazard manner, with biased sampling of n

166 49 lung cancer growth and additional benefit accrued in combination with cisplatin.

167 The levels of PhIP accrued in dyed hair from volunteers on a semicontrolled

168 f PhIP were comparable to the levels of PhIP accrued in hair of subjects with natural hair color.

169 and congenital heart anomaly burden, 34% was accrued in people under age 30 years in the poorest coun

170 deaths, obtained by multiplying person-time accrued in the cohort by mortality rates for a reference

171 pal specific expression in Arabidopsis--were accrued in the CRM1 of MPF2-like promoters.

172 is due to sudden release of strain that has accrued in the crystal of form I, which is a metastable

173 The outcomes measured were health-care costs accrued in the last year of life, number of inpatient da

174 cause of the different ways in which fitness accrues in the two sexes.

175 Given the amount of knowledge and data accruing in the neurosciences, is it time to formulate a

176 n is used to characterize the genetic damage accruing in these tumors.

177 hether the manner in which sedentary time is accrued (in short or long bouts) carries any clinical re

178 hether the manner in which sedentary time is accrued (in short or long bouts) carries prognostic rele

179 Despite the accruing insights in the use of these tools, delivery co

180 l review board approval was obtained at each accruing institution.

181 l hydrogen-bonding network which effectively accrues internal strain to elicit propulsion solely by e

182 genotyped the first 6005 European-Americans accrued into BioVU, Vanderbilt's DNA biobank, at five si

183 As the experience with lung transplantation accrues, it has become increasingly apparent that not al

184 incurred early, while environmental benefits accrue later.

185 g retrospectively reviewed 217 consecutively accrued lesions by using protocols that were HIPAA compl

186 ermine the ability of replication origins to accrue limiting factors and have the potential to reprog

187 Bleeding events accrued linearly over time, reaching 10.4% at 96 h post-

188 Despite the fact that there is rapidly accruing literature on CBCT, there are still no current

189 disease who had at least 3 years of annually accrued longitudinal data and 142 controls consisting of

190 Over 12-month follow-up, 274 (71%) survivors accrued lost earnings, averaging $26,949 +/- $22,447 (60

191 equently, replicating primary cells steadily accrue macroH2A1.2 at fragile regions, whereas macroH2A1

192 A total of 298 patients were accrued (median age, 68.8 [range, 32-94] years at day 10

193 year cohort of cataract surgery patients was accrued: Medicare, $36.4 billion; Medicaid, $3.3 billion

194 ioned cue in our procedure does not directly accrue model-free value and further suggest that the cue

195 charides (EPS), such that cospecies biofilms accrue more biomass and harbor more viable S. mutans cel

196 CTDs accrue more patients in new trials to offset that defici

197 ift from mid-Holocene to present: some areas accrue more permanent uplift than others.

198 tation rates, which imply that substitutions accrue more slowly than previously believed.

199 ransformed PEL cell lines, which have likely accrued mutations during the transformation process.

200 Consequently, such accrued neuroprotective deficits make neurons more vulne

201 when analysis was restricted to person-time accrued on ART with CD4 counts of at least 500 cells per

202 effects of higher temperatures are likely to accrue over time as nitrogen availability in grasslands

203 Although the benefits of statins accrue over time, treatment discontinuation is common.

204 were successfully genotyped in 9483 samples accrued over 4 mo into BioVU, the Vanderbilt University

205 nsistency in the total number of heart beats accrued over a lifetime across a range of animal species

206 A total of 2250 incident HF events accrued over a median follow-up of 20.6 y.

207 eptual knowledge (semantic memory), which is accrued over many years.

208 ach that takes advantage of a unique dataset accrued over several decades.

209 on laboratory and clinical evidence that has accrued over the last 20 years.

210 These spatial data, accrued over time and appended with detailed cohort info

211 isks, but the speed at which these risks are accrued over time is unknown.

212 How ecological and morphological diversity accrues over geological time has been much debated by pa

213 tion: Noisy evidence in favor of each option accrues over time, until the evidence in favor of one op

214 RDS was used to accrue participants at 27 sites (15 PWID sites and 12 MS

215 A prospectively accrued patient database was analyzed from September 1,

216 low incidence rate has made it difficult to accrue patients to prospective randomized trials.

217 ents, and 11 (26.8%, 95% CI 14.2-42.9) of 41 accrued patients (specifically in four patients with non

218 al measures were obtained from prospectively accrued patients during 8 weeks.

219 er Trials Group MA.31 phase 3 clinical trial accrued patients from 21 countries and randomized 652 wi

220 These clinical trials accrued patients included in this analysis from May 2010

221 erial behavioral measures from prospectively accrued patients with frontotemporal dementia to determi

222 pragmatic, open-label, randomised trial that accrued patients with histologically proven and complete

223 Among accrued patients, FISH group 1 breast cancers were stron

224 The phase 2 trial is no longer accruing patients.

225 In the single-patient stage, one patient was accrued per dose level.

226 pmental Cohort is a genotyped, prospectively accrued, population-based sample of almost 10,000 youths

227 ajor cause of neurological disability, which accrues predominantly during progressive forms of the di

228 The benefit of all strategies accrued primarily to relatives with a mutation associate

229 ubsequently in a cohort of 207 prospectively accrued primary neuroblastomas.

230 small case series and articles based on data accrued prior to 2000.

231 ly dense world, and substantial evidence has accrued regarding multitasking difficulties and cognitiv

232 o models, little knowledge has been directly accrued regarding the neurobiology of the opiate-addicte

233 s. 3% of the participants had >/=24 weeks of accrued remission; odds ratio, 5.91; 95% confidence inte

234 The first is to assess, in the face of accruing reports on the ingenuity of great ape tool use,

235 ttention as learning occurred and experience accrued searching for the same target object.

236 Accruing sedentary time in prolonged, uninterrupted bout

237 ay provide restorative benefit by mitigating accrued senescent burden.

238 s were enrolled in two separate cohorts that accrued sequentially: in cohort 1, patients were enrolle

239 genomic regions in independent prospectively accrued series of 176 white patients with BE/EAC and 200

240 Much new evidence has accrued since previous reviews were published.

241 responses also significantly decreased with accrued sleep debt.

242 unting perspective, there is an imbalance in accrued social costs and benefits.

243 rshes have a relatively open N cycle and can accrue soil organic matter rapidly.

244 iving kidney donors (LDs) also may expect to accrue some personal benefit following donation.

245 iants typically precludes the possibility of accruing statistical evidence that they are associated w

246 March 2015, 63 patients from a prospectively accrued study population who underwent MR imaging of the

247 ind, placebo-controlled, clinical trial that accrued subjects from five clinical sites in Mexico and

248 tions were similar in screened compared with accrued subpopulations.

249 In the future, once we have accrued sufficient cases, we aim to build on this study

250 nitial number of rapidly but non-selectively accrued synapses.

251 Background- Evidence has accrued that cardiopulmonary resuscitation quality affec

252 Much data have accrued that directional responses in the mammalian reti

253 ethod to identify individuals most likely to accrue the largest benefit from continued treatment.

254 ations 50% larger than humans, they may have accrued the energetic and mechanical benefits of out-of-

255 Medicaid patients accrued the highest unadjusted total costs ($113 380 +/-

256 Overall, 27 evaluable patients were accrued; the median number of prior therapies was 4.

257 d September 2014 (response rate, 71.0%) were accrued through 2 population-based Surveillance, Epidemi

258 In these systems, molecular complexity is accrued through sequential transformations to a mobile s

259 Nonrandom outcomes could accrue throughout ontogeny, or the processes that genera

260 ersity maintenance is how fitness advantages accrue to a species as it becomes rare, as this is the d

261 ortance of the marketing based benefits that accrue to Leadership in Energy and Environmental Design

262 of sperm velocity and that fitness benefits accrue to males from such adjustment.

263 Most cost savings are expected to accrue to Medicare, and most increased access to transpl

264 fits, including environmental benefits, that accrue to the broader community as well as the farmer.

265 ALYs gained and healthcare costs saved would accrue to the most disadvantaged quintiles in Australia.

266 emotional effect, and benefits often do not accrue to the payer; avoidable harm is accepted as norma

267 As metals become depleted or, conversely, accrue to toxicity, microbes will activate cellular resp

268 Among patients accrued to BCIRG-005, group 4 was not associated with si

269 Among patients accrued to BCIRG-006, only group 1 showed a significant

270 Patients and Methods Patients accrued to four sequential studies of ibrutinib were inc

271 r, 234, 241, and 235 evaluable patients were accrued to groups 1, 2, 3, and 4, respectively.

272 The proportions of HIV deaths that accrued to men and women at different stages in the HIV

273 Evidence has accrued to suggest that excessive intra-PFC mu-opioid re

274 croarray was made from 2123 of 3122 patients accrued to SWOG 9313, in which sequential doxorubicin (A

275 Results Of 17 patients accrued to the study, 15 had mutations in APC or CTNNB1

276 rch 2009 to December 2012, 153 patients were accrued to the study.

277 nteract is believed to reinforce the rewards accruing to mutual cooperation while simultaneously excl

278 a small but significant vocational advantage accruing to recipients of evidence-based supported emplo

279 lation, with 49.5% of the total health gains accruing to the 2 lowest quintiles.

280 placebo training, emotional WM training also accrued transfer benefits to a "gold standard" measure o

281 n in CCL2-deficient mice failed to maximally accrue Tregs and monocytic MDSCs.

282 Protocols and forms for 155 actively accruing trials in the National Cancer Institute's (NCI'

283 s in the poorest countries, while only 3% is accrued under age 30 years in high-income countries.

284 t species' benefits to assess are those that accrue unexpectedly or are wholly unanticipated.

285 The time to survival benefit did not accrue until 8 months after transplantation.

286 as being from the date the first patient was accrued until the last patient's actual or projected fin

287 planar 'white-light cavities', the benefits accrued upon optically interacting with a cavity - such

288 her screened in an independent prospectively accrued validation series of 58 cases (2010).

289 nce in frequency and average number of suits accrued varies widely by state of residence and sex.

290 species are more likely to win fights after accruing victories in their home territory but not after

291 tories in their home territory but not after accruing victories in unfamiliar locations.

292 The two primary end points were the accrued weeks of remission over a 52-week period, accord

293 olizumab treatment led to significantly more accrued weeks of remission than placebo (28% vs. 3% of t

294 ocols must assess whether benefits are being accrued, whether such "benefits" are real, and whether h

295 From 255 hospitals, 22,346 patients were accrued who underwent a colon resection in 2010, most co

296 Although these benefits accrue with both JAK-2 (TG101348) and JAK-1/2 (INCB01842

297 s that benefits of metformin may continue to accrue with longer treatment.

298 be taken, so larger absolute benefits would accrue with more prolonged therapy, and these benefits p

299 e case, cost and quality-adjusted life years accrued with the use of CTA ($74 869, 4.63 quality-adjus

300 tein microcrystals, roughly a micron across, accrue within infected cells.