ライフサイエンスコーパス: acentrosomal

1 phase and followed the fate of the resultant acentrosomal and centrosomal daughter cells.

2 most cell types, oocytes of many species are acentrosomal and must organize spindles in their absence

3 Here, we show that acentrosomal Arabidopsis cells that are mutant for the k

4 plant cortical microtubule array is a unique acentrosomal array that is essential for plant morphogen

5 These acentrosomal arrays support essential cell functions suc

6 organized by imaging microtubule dynamics in acentrosomal basal cytoplasts derived from these cells.

7 meiosis I in mouse oocytes, formation of the acentrosomal bipolar spindle takes 3-4 h, and stabilizat

8 Many acentrosomal cells exhibit prolonged spindle assembly, c

9 id not alter already-formed Golgi complexes, acentrosomal cells fail to reassemble an integral comple

10 By contrast, during this period, none of the acentrosomal cells had entered S phase.

11 Apoptosis of acentrosomal cells is mediated by JNK signaling, which a

12 experiments reveal that microtubules form in acentrosomal cells randomly within the cytoplasm.

13 Karyoplasts (acentrosomal cells) entered and completed mitosis.

14 ell-free extracts and experimentally derived acentrosomal cells, randomly oriented microtubules (MTs)

15 microtubule (MT)-dependent MT nucleation in acentrosomal cells.

16 go a normal anaphase and usually produce two acentrosomal daughter cells.

17 Plants employ acentrosomal mechanisms to organize cortical microtubule

18 the length and maintaining bipolarity of the acentrosomal meiotic spindle and in promoting the contac

19 required for the proper organization of the acentrosomal meiotic spindle in Drosophila melanogaster

20 The acentrosomal meiotic spindle poles do not have centriole

21 gmin in stabilizing the bipolar shape of the acentrosomal meiotic spindle.

22 yeast, nuclear-independent, self-organized, acentrosomal microtubule arrays are structurally and fun

23 rosome function and reveal a multi-component acentrosomal microtubule assembly pathway to establish i

24 , although Nek2B is not required to organize acentrosomal microtubule asters, we show that addition o

25 sin network interacts with the minus ends of acentrosomal microtubule bundles through the cytolinker

26 organization regulates the role of Golgi in acentrosomal microtubule growth in dendrites and in dend

27 l parameters for the self-organization of an acentrosomal microtubule network.

28 rs are sufficient to generate a steady-state acentrosomal microtubule network.

29 well understood, but less is known about how acentrosomal microtubule networks are formed.

30 al. demonstrate that Golgi outposts mediate acentrosomal microtubule nucleation and reveal it is cru

31 Here, we show that acentrosomal microtubule nucleation in plant cells invol

32 hese results identify a direct mechanism for acentrosomal microtubule nucleation within neurons and r

33 nd therefore provide a model system to study acentrosomal microtubule nucleation.

34 caused aberrant PLK1 aggregation that led to acentrosomal microtubule-organizing center (aMTOC) forma

35 We also show that (acentrosomal) microtubule asters fail to assemble in vit

36 nized independently of a centrosome, but how acentrosomal microtubules arrays form and whether they a

37 How neurons generate acentrosomal microtubules remains unclear.

38 rgery, vertebrate somatic cells form bipolar acentrosomal mitotic spindles, but the fate of these cel

39 -GCP6 (the non-core GCPs) may be involved in acentrosomal MT nucleation in plant cells.

40 This acentrosomal nucleation requires gamma-tubulin and CP309

41 ng that none were entirely selective for the acentrosomal pathway.

42 The acentrosomal pole lacks pericentrin, gamma-tubulin, and

43 lls eventually formed bipolar spindles by an acentrosomal pole-focusing mechanism.

44 formed that contain one centrosomal and one acentrosomal pole.

45 on pathways from chromatin, spindle MTs, and acentrosomal poles all contribute to robust bipolar spin

46 numerous microtubule plus ends growing from acentrosomal poles toward the metaphase plate.

47 or Nek6 function did not induce formation of acentrosomal poles, meaning that multipolar spindles wer

48 ugmin-independent MT nucleation process from acentrosomal poles, which becomes increasingly active ov

49 that produces a bipolar structure during the acentrosomal process of oocyte meiotic spindle assembly.

50 that EDE1, but not AUG8, is associated with acentrosomal spindle and phragmoplast MT arrays in patte

51 This screen identified 197 genes involved in acentrosomal spindle assembly, eight of which had no pre

52 M phase, required for the initial stages of acentrosomal spindle assembly.

53 is showed robust microtubule assembly of the acentrosomal spindle but frequent chromosome misalignmen

54 Bipolar acentrosomal spindle formation during meiosis in oocytes

55 own to nucleate microtubules, mechanisms for acentrosomal spindle formation remain unclear.

56 GSK3 beta) were found to be enriched at both acentrosomal spindle poles and the kinetochore region.

57 equired for the formation and maintenance of acentrosomal spindle poles in extracts prepared from Xen

58 Mouse eggs contain acentrosomal spindle poles when arrested at meiotic meta

59 gregation occurs in Drosophila oocytes on an acentrosomal spindle, which raises interesting questions

60 s undergo mitotic arrest with barrel-shaped, acentrosomal spindles during the rapid cycles of syncyti

61 s undergo mitotic arrest with barrel-shaped, acentrosomal spindles during the rapid S-M cycles of syn

62 ess in Caenorhabditis elegans, detailing how acentrosomal spindles form and revealing mechanisms requ

63 e not required for chromosome segregation on acentrosomal spindles in Caenorhabditis elegans oocytes,

64 a timely manner to promote elongation of the acentrosomal spindles that segregate homologous chromoso

65 (a microtubule-plus-end binding protein) in acentrosomal spindles, we also demonstrate that the spin

66 aphase central spindle functions to organize acentrosomal spindles.

67 crotubule minus ends in both centrosomal and acentrosomal spindles.