ライフサイエンスコーパス: acetamide

1 king place during rotation of the CN bond in acetamide.

2 including acetamide enolate and O-protonated acetamide.

3 an methionine's side chain or the N-terminal acetamide.

4 under mild conditions without removal of the acetamide.

5 olysis of the nitrilium ion yielded N-benzyl acetamide.

6 ea, 1,3-dimethyl urea, 1,1-dimethyl urea and acetamide.

7 presence of small-molecule inducers, such as acetamide.

8 itude more stable than acetamidine, urea, or acetamide.

9 arboxylation of tryptophan to yield indole-3-acetamide.

10 hexanoic acid, and n-octane and 2-ethylhexyl acetamide.

11 from compounds where the N-substituents were acetamides.

12 with MeOH and EtOH affording formamides and acetamides.

13 onformation generally preferred by secondary acetamides.

14 )-5,7-dimethylpyrazolo[1,5-a]pyrimidin -3-yl)acetamide].

15 a potent and selective sPLA2 inhibitor, 3-(3-acetamide 1-benzyl-2-ethylindolyl-5-oxy)propanesulfonic

16 l-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5- acetamide (1) was prepared and evaluated for their abili

17 sic agent (E)-2-(4,6-difluoro-1-indanylidene)acetamide, 1, has given rise to (E)-2-(4-chloro-6-fluoro

18 ogen bond in a simple enolate anion: lithium acetamide, 1.

19 ted by the selective sPLA(2) inhibitors 3-(3-acetamide-1-benzyl-2-ethylindolyl-5-oxy)propane sulfonic

20 Using the selective sPLA(2) inhibitor 3-(3-acetamide-1-benzyl-2-ethylindolyl-5-oxy)propane sulfonic

21 14-kDa secretory phospholipase A(2) by 3-(3-acetamide-1-benzyl-2-ethylindolyl-5-oxy)propanephosphoni

22 -(2-methoxybenzyl)- N-(4-phenoxypyridin-3-yl)acetamide ( 10, PBR28).

23 3- or 4-aminophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide (10 and 14) were prepared either without or wi

24 5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-3- yl]-acetamide ((11)C-DPA-713), has been described that binds

25 )-5,7-dimethylpyrazolo[1,5-a]pyrim idin-3-yl)acetamide ((125)I-iodo-DPA-713) SPECT/CT or (18)F-FDG PE

26 (2S)-2-amino-2-substituted-N-(4-methylphenyl)acetamides 12a-d, easily prepared in two steps from N-Bo

27 rophenoxy)-N-(4-oxo-4H-3,1-benzothiazin-2-yl)acetamide (13), were identified as a novel class of pote

28 l-5-yl)-2-phenyl-N-(2,4,6-trimethoxypheny l) acetamide (13a) and (+/-)-2-(5-dodecylisoxazol-3-yl)-2-p

29 (2S)-2-amino-2-substituted-N-(4-nitrophenyl)acetamides 16a-c, succindialdehyde (13), and benzotriazo

30 l-3-yl)-2-phenyl-N-(2,4,6-trimethoxypheny l) acetamide (16a), were selected for further study and wer

31 1-yl)pyrimidin-4-yloxy)benzo[d] thiazol-2-yl)acetamide (16p), a potent TRPV1 antagonist [rTRPV1(CAP)

32 relaxant (E)-2-(4,6-difluoro-1-indanylidene)acetamide, 17.

33 )-5,7-dimethylpyrazolo[1,5-a]pyri midin-3-yl)acetamide ((18)F-DPA-714) has been suggested to serve as

34 )-5,7-dimethylpyrazolo[1,5-a]pyri midin-3-yl)acetamide ((18)F-DPA-714), as a translational probe for

35 -1-yl)-N-(2,2,3,3,3-(18)F-pentafluoropropyl)-acetamide ((18)F-EF5) PET to monitor and predict tumor r

36 oxybenzyl)-2-(18)F-fluoro-N-(2-phenoxyphenyl)acetamide ((18)F-PBR06) for detecting alterations in tra

37 entified as [18F]2-fluoro-N-(2-phenoxyphenyl)acetamide ([18F]11).

38 luoroethoxy)benzyl)-N-(4-phenoxypyridin-3-yl)acetamide ([18F]FEPPA).

39 ently bonded to N-(4-hydroxy-3-methoxybenzyl)acetamide (2) by ether or carbonate linkages.

40 )-5,7-dimethylpyrazolo[1,5-a]pyrimidin- 3-yl)acetamide (2, DPA-714), were synthesized and biologicall

41 1-methylethyl)phenyl]-2,6-dioxo-7H-purine- 7-acetamide, 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-

42 Acetamide, 2-amino-N-[[3,5-bis(trifluoromethyl)phenyl]-m

43 ino)-2-pyrimidinylthio-(N-beta-hydroxyethyl) acetamide (200 mg/kg) induced a wave of DNA synthesis in

44 ds for the synthesis of 7-substituted indole acetamides 3 and N-methyl (indol-7-yl)oxoacetates 6.

45 4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2- yl)acetamide (3).

46 -4H-chromen-8-yl)dibenzo[b,d]th io-phen-1-yl)acetamide, 39; DNA-PK IC(5)(0) = 5.0 +/- 1 nM, IR dose m

47 -1-(3-aminophenyl)-2-(1-pyrrol idinyl) ethyl]acetamide (5) were synthesized and evaluated in mice for

48 drothiazol-5-yl}-N-(3-tr ifluoromethylphenyl)acetamide (5), showed a mixed-type inhibition pattern, w

49 5-b]pyridin-2-ylthio)-N-(3,4-dimethoxyphenyl)acetamide (5a) as a hit compound with a Ki value of 217

50 yl]-ethyl}-[1,3,4]thiadiaz ol-2-yl)-2-phenyl-acetamide 6, exhibited similar potency and better solubi

51 generate a C-3 quaternary carbon resulted in acetamide 6, which showed CCK-A receptor binding selecti

52 The N-methyl acetamide 7a showed the optimal in vitro profile and was

53 rifluoromethyl)phenyl)-N-(pyridin-3-ylmethyl)acetamide] (8-azaquinazolinone) without any basic group.

54 -2-(4-ethyl-6,6-dimethyl-2-oxomorpholin-3-yl)acetamide (87), which, in addition to fungicidal activit

55 zol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl ]acetamide, a helicase-primase inhibitor for the treatmen

56 enthalpies at the alpha carbons of acetone, acetamide, acetic acid, and acetyl fluoride, which were

57 2 kcal/mol, depending on substituents on the acetamide acyl group.

58 Titration of the subcomplex with iodo[(14)C]acetamide after prolonged treatment with CuCl(2) in the

59 rahydro-7H-purin-7-yl)-N-(4-isopropylphenyl) acetamide) after its initial stimulation (and the calciu

60 osaminidase inhibition by an azetidine ADMDP-acetamide analogue is compared to an azetidine carboxyli

61 n the proline amides is found with the ADMDP-acetamide analogues bearing an acetamidomethylpyrrolidin

62 -5-oxo-3-vinyl-(1, 5-dihydropyrrol-2-ylidene)acetamide and 3-methyl-5-oxo-4-vinyl-(1, 5-dihydropyrrol

63 used to compute the CN rotation barriers for acetamide and eight related compounds, including acetami

64 oro-2,4-dimethoxyphenyl)-thioureido]-phenyl)-acetamide and its 2-fluoro-benzamide derivative inhibite

65 ent parameters (bis(trimethylsilyl)trifluoro-acetamide and sterol exposure time, sterol concentration

66 e aliquots were then treated with iodo[(14)C]acetamide and the incorporation of radioactivity was mea

67 drolysis of 1 with hydrochloric acid affords acetamide and the previously known diarylhydroxytelluron

68 -5-oxo-4-vinyl-(1, 5-dihydropyrrol-2-ylidene)acetamide and the third was 4-methyl-3-vinylmaleimide (M

69 to replace protecting groups with N-terminal acetamides and C-terminal methyl amides led to the intro

70 rise to a mixture of indanyl (or tetralinyl) acetamides and dehydrotetralins (or pallidols) (both or

71 The reaction of N-allyl-N-(2-halobenzyl)-acetamides and derivatives was investigated in liquid am

72 cological activities of a series of indole-3-acetamides and related compounds derived from this lead.

73 ons from a series of secondary N-(4-X-benzyl)acetamides and tertiary amides to the phthalimide-N-oxyl

74 With the acetamides and the alkanamides almost exclusive HAT from

75 mino]-N-hydroxy-2-(tetrahydro-2H -pyran-4-yl)acetamide, and LF at the LF-active site.

76 onic spectra of formamide, N-methyformamide, acetamide, and N-methylacetamide at 300 K calculated usi

77 ent in potency over the best of the indole-3-acetamides, and LY315920 (6m) was selected for evaluatio

78 oglycans have been found to exist as amines, acetamides, and N-sulfonates.

79 )-5,7-dimethylpyrazolo[1,5-a]py rimidin-3-yl)acetamide] and [(11)C]SSR180575 (7-chloro-N,N-dimethyl-5

80 des has been realized using N-(2-aminophenyl)acetamide (APA) as a new bidentate directing group for t

81 de and 2-(6-methylpyridin-2-yl)-N,N-diphenyl-acetamide are described along with results from the chem

82 Thus, N-(benzothiazolyl)-2-phenyl-acetamides are valuable drug candidates for further stud

83 idine give pK(a)(C) = 28.4 for ionization of acetamide as a carbon acid.

84 The utilization of N-(2-aminophenyl)acetamide as a novel directing group, Mn(OAc)2 as a co-o

85 s can be significantly enhanced by using the acetamide as a quasi-leaving group in a subsequent conve

86 by addition of ethylene glycol, glycerol and acetamide as small organic co-solutes.

87 otent and selective 2-amino-N-pyrimidin-4-yl acetamides as hA2A receptor antagonists with excellent a

88 l the development of functionalized indole-3-acetamides as inhibitors of hnps-PLA2.

89 gioselective palladium(II)-catalyzed primary acetamide assisted ortho arylation of arylacetamide has

90 In the same study, a polyamide with an acetamide at the beta-position of the gamma-turn resulte

91 of the conformational probe, methyl coumarin acetamide, attached specifically to the ryanodine recept

92 cular C-N and C-O cyclization of N-(biphenyl)acetamides based on the substituent electronic effects i

93 The barrier to rotation of "mimics" for acetamide-based radicals are estimated.

94 and S [N-(4-(3-acetamidophenyl)thiazol-2-yl-acetamide)] bind to CG and TA base pairs, respectively.

95 Unlike the residues forming the acetamide binding cavity, these acidic side-chains are n

96 xylidino)-2-pyrimidinylthio (N-beta-hydroxyl)acetamide (BR931) alter hepatic sex steroid metabolism a

97 des are alkylated in the absence of indole-3-acetamide but not in its presence.

98 .8 x 10(-8) M(-1) s(-1) for deprotonation of acetamide by quinuclidine (pK(BH) = 11.5) and k(BH) = 2-

99 by deuterioxide ion and for deprotonation of acetamide by quinuclidine.

100 In addition, the primary acetamide can be manipulated into synthetically importan

101 dendrimers in ascending order at pH 7.4 was: acetamide-capped, -NHC(O)CH3, neutral charge; carboxylic

102 attributed to chelate formation between the acetamide carbonyl group and the glycosidic oxygen in th

103 Polyamide 3, with an alpha-acetamide, caused no significant evidence of rodent toxi

104 mer complex and the addition of the inducer, acetamide, causes a conformational change which alters t

105 5-bromofuran-2-yl)-4-oxo-4H-chromen-3-yl)oxy)acetamide (CB7993113), was further tested for its abilit

106 first report where functionalizable primary acetamide (-CH2CONH2) is used as a directing group for C

107 o[1,2-a]pyrimidin-9-yl)dibe nzothiophen-1-yl]acetamide) combined high potency against the target enzy

108 30 compounds described, the most active were acetamides containing alkylsulfonyl substituents.

109 2-yl)-6-(trifluoromethyl)pyrimidin-2-ylt hio]acetamide (CP9), that binds to Hsp90(alpha/beta) and dis

110 2-[5-(3-methylphenyl)-1-octyl-1H-indol-3-yl]acetamide (cysmethynil).

111 2-[5-(3-methylphenyl)-1-octyl-1H-indol-3-yl]acetamide (cysmethynil).

112 tions of N-(cyclohex-2-enyl)-N-(2-iodophenyl)acetamides depend critically on the configurations of th

113 The AmiC.AmiR butyramide complex exhibits acetamide-dependent, sequence-specific RNA binding activ

114 9) and the C1 N-isopropyl-N-(4-methoxyphenyl)acetamide derivative of 3-(1H-Indazol-3ylmethyl)-3-methy

115 ydro)octafluoro[2.2]paracyclophane, from its acetamide derivative utilizing the Cadogan method led to

116 However, the C-5 acetamide derivative, 3b, was greater than 100-fold sele

117 ctivating oximes, predominantly hydroxyimino acetamide derivatives (for hAChE) and imidazole-containi

118 reen, we identified 2-(2-oxo-morpholin-3-yl)-acetamide derivatives as fungicidal agents against Candi

119 bond in a series of N-cycloalkenyl-N-benzyl acetamide derivatives have been measured in different so

120 stitued piperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide derivatives, showed low nanomolar inhibitory a

121 sertion of alpha-diazo-alpha-(phenylsulfonyl)acetamides derived from alpha-amino acids, which possess

122 The cis-directing effect was studied in N-acetamide dipeptoid model systems and evaluated in terms

123 -dimethylpyrazolo[1,5-alpha]pyrimi dine-3-yl)acetamide (DPA-714) is a radioligand for the 18-kDa tran

124 idazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)-acetamide (EF5) allows for a comparative assessment of t

125 midazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide (EF5) and beta-hCG and pimonidazole, two extri

126 midazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide (EF5) was coadministered with the second one.

127 ole-1[H]-y1)-N-(2,2,3,3,3-pentafluoropropyl)-acetamide (EF5), we showed that the brain is hypoxic dur

128 henyl)sulfonyl]amino]-N-(3-pyridinyl methyl)-acetamide (EMPA), suppressed this effect, whereas a sele

129 amide and eight related compounds, including acetamide enolate and O-protonated acetamide.

130 s are generally more potent than their ADMDP-acetamide equivalents.

131 ging to the N-(4-(3-aminophenyl(thiazol-2-yl)acetamide family.

132 to an activated state (high methyl coumarin acetamide fluorescence) as T-tubule depolarization did.

133 containing nucleotide gave rise to undesired acetamide formation resulting from nucleophilic attack o

134 , whereas the competitive inhibitor indole-3-acetamide fully protects the enzyme from inactivation.

135 e is a good replacement for the conventional acetamide functionality found in oxazolidinones.

136 potency of thiotetroamide C ascribed to the acetamide group and the unusual enzymology involved, we

137 The acetamide group enables regioselective oxidative ortho-C

138 intramolecular hydrogen bond to the adjacent acetamide group.

139 he phenyl was para substituted with amine or acetamide groups, the NR1A/2B potency order was butynyl

140 6336 (6n-2), a hydroxy-substituted adamantyl acetamide, has been identified as a novel, potent inhibi

141 silylation employing N, O-bis(trimethylsilyl)acetamide, hexamethyldisilazane, and 1-(trimethylsilyl)i

142 high in their 2-hydroxy-N-(2-hydroxyphenyl) acetamide (HHPAA) concentration (40-48microg/g DM).

143 (HBOA-d4) and 2-hydroxy-N-(2-hydroxyphenyl) acetamide (HHPAA-d4) were synthesized, to allow quantifi

144 l N-[(5-hydroxy-1H-imidazole-2yl)methylidene]acetamide (HIMA) compound.

145 PMA-resistant TR19-9, and hexamethylene bis-acetamide (HMBA)- and PMA-resistant DS19/R1.

146 dihydrophenanthridin-2-yl)(N,N-dimethylamino)acetamide hydrochloride (PJ34), using virtual screening;

147 -acetylglucosamine regioisomer the picolinyl-acetamide hydrogen bond persists and leads to an enhance

148 ryptophan mono-oxygenase) and iaaH (indole-3-acetamide hydrolase).

149 as acetic acid, benzoic acid, formaldehyde, acetamide, hydroxyacetic acid, oxoacetic acid, hydroxyac

150 eparation of dendrimers with terminal amino, acetamide, hydroxyl, and carboxylate groups was obtained

151 The location of bound indole-3-acetamide in the active site allows identification of re

152 hesis of C4-, C7-aryl-substituted 1-naphthyl acetamides in good yields.

153 ts, in contrast to other aliphatic secondary acetamides in which significant E-rotamer populations ar

154 ucer of HEXIM1 expression, hexamethylene-bis-acetamide) in PyMT mice resulted in inhibition of metast

155 14 (2-(triethylamino)-N-(2,6-dimethylphenyl)-acetamide) induces internal pore blockade of single card

156 the mouse homolog of human hexamethylene bis-acetamide inducible-1 (HEXIM-1), regulates the pTEFb act

157 We report on the role of hexamethylene-bis-acetamide-inducible protein 1 (HEXIM1) as an inhibitor o

158 e previously reported that hexamethylene bis-acetamide-inducible protein 1 (HEXIM1) inhibits ERalpha

159 t the transcription factor Hexamethylene-bis-acetamide-inducible protein 1 (HEXIM1) is a tumor suppre

160 ass of compounds, 1,3-diaryl-[1H]-pyrazole-4-acetamides, initially identified from their ability to i

161 damine dimers form when tetramethylrhodamine acetamide is attached to two different sites in the N-te

162 he heteroatomic core of a pyrazolopyrimidine acetamide is sufficient to induce complex binding to wil

163 idazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide] is such a drug, and it has been shown to be p

164 ptical assay based on the hypotonic lysis of acetamide-loaded mouse erythrocytes.

165 ensitive fluorescence probe, methyl coumarin acetamide (MCA), was incorporated into RyR in a protein-

166 hyl-N-(2-[1-pyrrolidinyl]cyclohexyl) benzene-acetamide methanesulfonate (U-50,488H; 1 microM), and ba

167 2-[(Diphenylmethyl)sulfinyl]acetamide (modafinil, (+/-)-1) is a unique dopamine upta

168 tamide, confirming specificity for the alkyl acetamide moiety and showing that the primary element of

169 is simply the sterically unhindered terminal acetamide moiety of an acetylated lysine residue.

170 vity forms a specific binding pocket for the acetamide moiety.

171 The N-methylpiperazine acetamide (MPA) of ampicillin was adsorbed into polyelec

172 ,6-dioxo-1,3-dipropyl-1H-purin-8-yl)p henoxy]acetamide (MRS 1754).

173 ,2,4]-triazolo[1,5-c]quinazolin-5-yl]benzene acetamide (MRS1220) at the A(3) receptor and xanthine am

174 ere determined in D(2)O for deprotonation of acetamide, N,N-dimethylacetamide, and acetate anion by d

175 tly via the acetyl group with the oxygen and acetamide nitrogen hydrogen-bonded to the protein and th

176 upper side chain (proton donor) and glycine acetamide of the lower side chain (proton acceptor).

177 A regioselective oxidation of N-indan-4-yl-acetamide or N-(5,6,7,8-tetrahydronaphthalen-1-yl)acetam

178 3-(trifluoromethyl)-1H-pyrazol-1-yl]-phe nyl}acetamide (OSU-03012) killed primary human glioma and ot

179 3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl }-acetamide (OSU-03012) on both primary and glioblastoma c

180 3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a previously characterized PDK1 i

181 3-(trifluoromethyl)-1H-pyrazol-1-yl]phen yl]-acetamide (OSU-03012).

182 of indole-based ligands characterized by an acetamide, oxalylamide, or carboxamide chain, respective

183 luoroethoxy)benzyl)-N-(4-phenoxypyridin-3-yl)acetamide PET scan.

184 were shown to be optimal for activity at the acetamide position.

185 is of aqueous solutions of alpha-(methylthio)acetamide produced unexpectedly large quantities of acet

186 The ESI-MS readout of the resulting acetamide products reproduced the selectivity factors fr

187 The pyridin-4-yl alpha-substituted acetamide products were obtained in moderate to high yie

188 ammonium, nitrate, nitrite, urea, formamide/acetamide, purines, pyrimidines, polyamines, amino acids

189 5 mM 2(triethylamino-N-(2,6-dimethyl-phenyl)acetamide (QX-314) to block voltage-dependent Na+ curren

190 when 2(triethylamino)-N-(2,6-dimethylphenyl)acetamide (QX-314) was omitted from the recording pipett

191 tic [2-(triethylamino)-N-(2,6-dimethylphenyl)acetamide] (QX-314).

192 ecular homolytic substitution, S(H)2, of the acetamide radical fragment by a H atom is the most likel

193 de produced unexpectedly large quantities of acetamide radicals that were identified by time-resolved

194 activation kinetics of the lead hydroxyimino acetamide reactivator of hAChE, when analyzed in terms o

195 rahydro-7H-purin-7-yl)-N-(4-isopropylphenyl )acetamide] reduces cold hypersensitivity in rodent model

196 ivatized to the corresponding thiourea and N-acetamides, respectively, and were quantified by positiv

197 leimide (SM), thiol-vinylsulfone (SV), thiol-acetamide (SA), penicillamine-thiol-maleimide (PM) or pe

198 ivity relationships of a lead pyrimidin-4-yl acetamide series to provide potent and selective 2-amino

199 yl-3,5-dihydro-4H-pyridazino[4 ,5-b]indole-1-acetamide), showed a significant binding in the lenti-CN

200 line68 in myoglobin has been replaced by the acetamide side chain of asparagine in an attempt to engi

201 achieved when one of the phenyl rings of the acetamide side chain was replaced with an alkyl group, p

202 oimidazol-1[H]-yl)-N-(3,3,3-trifluoropropyl) acetamide staining.

203 roarylmethyl)piperazine 1a, benzamide 2, and acetamides such as 3a,b exhibit poor oral bioavailabilit

204 the 3-(2-phenethylamino)-6-methylpyrazinone acetamide template (e.g., 1) which resulted in the modif

205 ethylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl] acetamide (termed CK37) that inhibited purified recombin

206 tions with substrates (allyl GlcNAc, N-allyl acetamide) that were previously not possible for the cor

207 yl isocyanate, acetone, propionaldehyde, and acetamide-that had not previously been reported in comet

208 the chloroacetamide was fully reduced to an acetamide the pentasaccharides were obtained in four and

209 the key deficiency of noncovalent pyridinone acetamide thrombin inhibitor L-374,087 (1), namely, its

210 hydroxyalkylation with an N-protected 2-oxo-acetamide to close the heterocyclic ring.

211 Addition of the inducing ligand acetamide to the complex trips the molecular switch, cau

212 2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide ] to investigate the influence of KCC2 functio

213 N-ethyl-2-(7-methyl-8-oxo-2-phenylpurin-9-yl)acetamide) to determine nondisplaceable distribution vol

214 ino)-2-pyrimidinylthio-(N-beta-hydroxyethyl) acetamide) to male wistar rats induced a wave of hepatoc

215 rocyte lysis assay based on UT-B-facilitated acetamide transport.

216 ntiomer, (R)-alpha-ethyl-2-oxo-1-pyrrolidine acetamide (UCB L060).

217 is described to access unsymmetrical diaryl acetamides under TM-free conditions from sec- and tert-a

218 econdary amine or a readily removable Cbz or acetamide unit.

219 usceptibility patterns, citrate utilization, acetamide utilization, and assimilation of inositol and

220 yl)phenyl)-N-(1-(5-methoxypyridin-2-yl)ethyl)acetamide], we demonstrated that polyunsaturated lipids,

221 arbony lamino]-2-(4-hydroxy-3-methoxyphenyl) acetamide), were further characterized in enzyme, cellul

222 rker EF5 [2-8-N-(2,2,3,3,3-pentafluoropropyl)acetamide] were done in serial tumor slices.

223 in our previous paper, a series of indole-3-acetamides which possessed potency and selectivity as in

224 the auxins indole-3-acetic acid and indole-3-acetamide, which were produced by various (micro)algae s

225 [(E)-(5-hydroxy-1H-imidazol-2-yl)methylidene]acetamide, which, to our knowledge, has not been previou

226 had little or no incorporation of iodo[(14)C]acetamide, while the others that were treated with dithi

227 mide or N-(5,6,7,8-tetrahydronaphthalen-1-yl)acetamide with potassium permanganate followed by acidic

228 ontinued SAR development to produce indole-3-acetamides with additional functionalities which provide

229 yclohex-2-enyl)-N-(2-iodo-4,6-dimethylphenyl)acetamides with an additional ortho-methyl group did not

230 f alpha,alpha-difluoro-alpha-(trimethylsilyl)acetamides with aryl and heteroaryl bromides catalyzed b

231 lved the reaction of bis(ethylsulfenylacetyl)acetamides with dimethyl(methyl)thiosulfonium tetrafluor