ライフサイエンスコーパス: acetoxy

1 e most useful for asymmetric alkylation of 3-acetoxy-1,3-diphenylpropene and less suitable/effective

2 reoselectivity applied to the reactions of 4-acetoxy-1-(N-hydroxyphenyacetamido)cyclopentene (8).

3 onding succinimide analog of N-5-maleimido-2-acetoxy-1-benzoic acid did not inhibit either enzyme act

4 The reduction of the 2-acetoxy-1-C-oxacarbenium ion intermediates proceeds with

5 4-Acetoxy-1-phenylacetamidocyclopentene (9), however, affo

6 Taxa-4(20),11(12)-dien-5 alpha-acetoxy-10 beta-ol 6 has been identified as an early sta

7 droxylation at C10 to yield taxadien-5 alpha-acetoxy-10 beta-ol.

8 elimination" substitution reaction of 3 beta-acetoxy-17-chloro-16-formylandrosta-5,16-diene (2) and a

9 -elimination" substitution reaction of 3beta-acetoxy-17-chloro-16-formylandrosta-5,16-diene (2) and b

10 alogous thioesters, S-tert-butyl (2R*,3R*)-3-acetoxy-2,3-2H2-butanethioate (3) and its (2R*,3S*) dias

11 ospecifically labeled tert-butyl (2R*,3R*)-3-acetoxy-2,3-2H2-butanoate (1) and its (2R*,3S*) diastere

12 sh vacuum pyrolysis studies of substituted 6-acetoxy-2,4-cyclohexadienones (3 and 10) from 300 to 500

13 are generated during hydrolysis of 4-aryl-4-acetoxy-2,5-cyclohexadienones, 2c and 2d, and O-(4-aryl)

14 rranged spongian diterpenes (8-substituted 6-acetoxy-2,7-dioxabicyclo[3.2.1]octan-3-one and 6-substit

15 Details of the first synthesis of the 6-acetoxy-2,7-dioxabicyclo[3.2.1]octan-3-one ring system,

16 icyclo[3.2.1]octan-3-one and 6-substituted 7-acetoxy-2,8-dioxabicyclo[3.3.0]octan-3-one) are reported

17 In addition, the first synthesis of 7-acetoxy-2,8-dioxabicyclo[3.3.0]octanones containing quat

18 Compound 2, 1-(2(R)-[1(S)-acetoxy-2-[2(S)-(2,4-difluoro-benzoylamino)-3-phenyl-pro

19 A model system using the carcinogen, N-acetoxy-2-acetylaminofluorene (AAAF), was used to synthe

20 on-cycling cultured human cells exposed to N-acetoxy-2-acetylaminofluorene (NA-AAF), which generates

21 mid DNA containing bulky adducts formed by N-acetoxy-2-acetylaminofluorene or benzo(a)pyrene diol epo

22 iol epoxide, aflatoxin B1 8,9-epoxide, and N-acetoxy-2-acetylaminofluorene.

23 pyrimidine dimers,(6-4) photoproducts, and N-acetoxy-2-aminofluorene (AAF) adducts by an excision rep

24 Pd(0)/InI-mediated allylation of 4-acetoxy-2-azetidinone is used to install the beta-amino

25 eleutherobin, the steroid derivative 17beta-acetoxy-2-ethoxy-6-oxo-B-homo-estra-1,3,5(10)-trien-3-ol

26 ,2,5,5-tetramethylpyrrolidine (AMCPy), and 1-acetoxy-3-(acetoxymethoxy)carbonyl-2,2,5,5-tetramethylpy

27 nyl-2,2,6,6-tetramethylpiperidine (AMCPe), 1-acetoxy-3-methoxycarbonyl-2,2,5,5-tetramethylpyrrolidine

28 d 3 were obtained in five steps from ethyl 4-acetoxy-3-oxobutanoate and 6-iodo-3-methyl-1,3-hexadiene

29 4-Acetoxy-4-(benzothiazol-2-yl)-2,5-cyclohexadien-1-one, 1

30 e Lewis acid-promoted cyanation of (5R,6S)-2-acetoxy-4-(benzyloxycarbonyl)-5,6-diphenyl-2,3,5,6-tetra

31 d that 1-N-chrysenyl and 1-N-phenanthrenyl 3-acetoxy-4-aryl-2-azetidinones have potent anticancer act

32 The enantioselective total syntheses of 11-acetoxy-4-deoxyasbestinin D and asbestinin-12 have been

33 thesized the acyl-protected hydroxylamines 1-acetoxy-4-methoxycarbonyl-2,2,6,6-tetramethylpiperidine

34 acid- and base-catalyzed decomposition of 4-acetoxy-4-methyl-2,5-cyclohexadienone, 2b, in (18)O-H(2)

35 alyzed and acid-catalyzed decomposition of 4-acetoxy-4-phenyl-2,5-cyclohexadienone, 2a, generates the

36 bound to an oviposition pheromone (5R,6S)-6-acetoxy-5-hexadecanolide (MOP).

37 n hydride-mediated cyclizations of 1-nitro-2-acetoxy-5-hexenes 7a-g having multiple substitutions on

38 The steroid SC17599 (17alpha-acetoxy-6-dimethylaminomethyl-21-fluoro-3-ethoxypregna -

39 nance measurements identified NX-2 as 3alpha-acetoxy-7alpha,15-dihydroxy-12,13-epoxytrichothec-9-ene.

40 N-Acetoxy-AalphaC also formed an adduct at Tyr(332).

41 -acetyloxy-2-amino-9H-pyrido[2,3-b]indole (N-acetoxy-AalphaC), and their [(13)C6]AalphaC-labeled homo

42 ious omega-[bis(acetoxy)]alkyl or omega-[bis(acetoxy)]alkoxyalkyl groups are substituted at the 3'-am

43 elated compounds in which various omega-[bis(acetoxy)]alkyl or omega-[bis(acetoxy)]alkoxyalkyl groups

44 -catalyzed regioselective hydration of gamma-acetoxy-alpha,beta-acetylinic ester by the assistance of

45 imple primary, secondary, and tertiary gamma-acetoxy-alpha,beta-acetylinic esters, even those bearing

46 8) s(-1)) in all solvents studied, and the 2-acetoxy analogue (3b) reacted much faster than related r

47 C-4 acetoxy and acetylsalicyloxy derivatives were also studi

48 ur base-initiated alpha,beta-eliminations of acetoxy and mesyloxy esters and their analogous thioeste

49 ubstrates in EtOH/H(2)O, with beta-tosyloxy, acetoxy, and 3-trifluoromethylphenoxy nucleofuges.

50 pyridinium, sulfonium, thiol, carbonitrile, acetoxy, and amino derivatives.

51 d via hydrosilylation of the corresponding o-acetoxy arylacetylenes.

52 inversion of one alpha-d-glucose into a 5-C-acetoxy-beta-l-idose unit possessing a (1)C4 conformatio

53 oliferation; however, the 4-pyridinyloxy and acetoxy compounds were also potent inhibitors of NQO1 ac

54 of t-Bu-MacE and a structurally related des-acetoxy congener to substituted pyrroles in the presence

55 The iodocyclization of acetoxy-containing 2-(1-alkynyl)anisoles and subsequent

56 ] and -[5.3.0] skeletons possessing an alpha-acetoxy cyclopentadienone.

57 teria: N-acetylglycine, D-lactic acid, and 2-acetoxy-D-propanoic acid.

58 Among other derivatives tested, the alpha-acetoxy derivative 7 affords the highest enantioselectiv

59 ylated glycals by a new, mild anomeric S(N)'-acetoxy displacement with Hg(CN)(2)/HgBr(2)/TMSCN.

60 resent the first evidence that a compound (3-acetoxy ecgonine methyl ester) exists that prevents inhi

61 acetate is trans to palladium and with beta-acetoxy elimination when acetate is cis.

62 se-catalyzed hydrolysis of a mixture of C-35 acetoxy epimers indicated a 35R absolute configuration f

63 om a conjugate base (E1cB(I)) mechanism with acetoxy ester 3, acetoxy thioester 4, and mesyloxy thioe

64 steps, 3.7% global yield), via a nor-labdane acetoxy ester, has been achieved starting from commercia

65 creased formation of ethyl esters, acetates, acetoxy esters and alcohols, thus allowing the authentic

66 in the elimination of acetic acid from beta-acetoxy esters and thioesters.

67 (1), reductive acetylation to give the alpha-acetoxy ether (3), and cyclization on treatment with a L

68 at, under mild acidic conditions, many alpha-acetoxy ethers can be further reduced to the correspondi

69 to be converted into the corresponding alpha-acetoxy ethers in good to excellent yields.

70 yl (8), 4-methoxyphenoxycarbonyl (9), and (1-acetoxy)ethoxycarbonyl (10) and a bis-carbonate ethoxyca

71 in A have demonstrated the importance of the acetoxy functionality on the A-ring in its activity as a

72 ccessful route involved the reaction of beta-acetoxy-gamma-thianyl carbonyl compounds with dimethyl(m

73 The presence of the acetoxy group at C(3) of the beta-lactams has proven to

74 nsporter binding potency, while a hydroxy or acetoxy group at the 2'-position exhibited increased bin

75 substitution reaction of the bay-region C10 acetoxy group in four stereoisomeric 7,8,9,10-tetraaceto

76 (S)-Acetoxy group in the succinimide precursor was initially

77 Mass spectrometry and NMR indicate that an acetoxy group is covalently bound to the delta-meso-carb

78 eria and plants, the replacement of the beta-acetoxy group of O-acetyl-L-serine (OAS) by a thiol to g

79 beta-replacement reaction in which the beta-acetoxy group of O-acetyl-L-serine (OAS) is replaced by

80 acteria and plants, substitution of the beta-acetoxy group of O-acetyl-l-serine (OAS) with inorganic

81 eria and plants, the replacement of the beta-acetoxy group of O-acetyl-l-serine by a thiol to give l-

82 vity to give beta-C-arylglucosides without 2-acetoxy group participation.

83 ic attack at the carbonyl carbon of the beta-acetoxy group.

84 Acetoxy groups are labile and thus not suitable protecti

85 R6 and R7 hydroxyl groups by alkoxy groups, acetoxy groups, or benzyloxy groups could yield compound

86 sterase-mediated hydrolysis of the omega-bis(acetoxy) groups and give rise to 5- or 6-membered ring c

87 rtiary carbon atom adjacent to the omega-bis(acetoxy) groups, was also substantially less active than

88 yclo[2.1.1]hexanes containing bromo, fluoro, acetoxy, hydroxy, azido, imidazole, thiophenyl, and iodo

89 ramethyl-piperidin-1-yl)oxyl (TEMPO) and bis(acetoxy)iodobenzene (BAIB).

90 d that a trans relationship of palladium and acetoxy is essential for acetate elimination.

91 ase, Fasp; aldo-keto reductase, Ypr1p; alpha-acetoxy ketone reductase, Gre2p).

92 chloroaldehyde or an alpha-phenoxy- or alpha-acetoxy ketone with a substituted benzyl hydroxylamine t

93 incubation of the cells with 50 microM BAPTA acetoxy methyl ester (AM) or thapsigargin also blocked a

94 aminoethyl ether)-N,N,N',N'-tetraacetic acid-acetoxy-methyl ester also reduces gadd153 induction by 2

95 erin for the ATP assay or loaded with Fluo-3-acetoxy methylester for intracellular calcium measuremen

96 is(carboxyethyl)-S-(and 6)carboxyfluorescein acetoxy methylester/fluorometry.

97 generated from hydrolysis or photolysis of O-acetoxy-N-(4-(benzothiazol-2-yl)phenyl)hydroxylamine 8,

98 tly modified using the model carcinogen 2-(N-acetoxy-N-acetylamino)fluorene.

99 )-stemoamide was achieved in 11 steps from 5-acetoxy-N-crotyl pyrrolidinone.

100 ): atropine (nonselective, 9.0) > 4-diphenyl-acetoxy-N-methyl piperidine methiodide (M3/M1, 8.6) > pa

101 Furthermore, pirenzepine, diphenyl-acetoxy-N-methyl-piperidine and mecamylamine had no meas

102 y M1- (pirezenpine; 2 mum) and M3- (diphenyl-acetoxy-N-methyl-piperidine; 100 nm) receptor blockers,

103 c substrates such as acetylthiocholine and 7-acetoxy-N-methylquinolinium (M7A) bind to the peripheral

104 [reaction: see text] Alpha-acetoxy-N-nitrosomorpholine (7) has been synthesized sta

105 pH compared with its carbon analogue, alpha-acetoxy-N-nitrosopiperidine, is also consistent with the

106 in the stimulation of repair synthesis by N:-acetoxy-N:- acetylaminofluorene, but are proficient in t

107 a tetra-acetylated inhibitor (2E)-3-[3,4-bis(acetoxy)phenyl]-2-propenoate-N-[(2E)-3-[3,4-bis(acetylox

108 polar adducts are found after reaction of N-acetoxy-PhIP with the oligonucleotide.

109 hyl-6-phenylimidazo[4,5-b]pyridine (PhIP), N-acetoxy-PhIP, with a single-stranded 11mer oligodeoxyrib

110 CCTXGCCTCTC, where X = C, A, G, or T) with N-acetoxy-PhIP.

111 g the C8-dG adduct formed by reaction with N-acetoxy-PhIP.

112 cridinium iodides bearing bulky saturated (3-acetoxy)propyl or (E)-3-(morpholin-4-yl)-3-oxopropenyl s

113 to TAB, predicted that modifications to the acetoxy residue of the lead inhibitor could exploit bind

114 temperature employing PIDA as a nonmetallic acetoxy source.

115 nes with 4-nitrophenoxy, 4-pyridinyloxy, and acetoxy substituents at the (indol-3-yl)methyl position

116 e leads to ring opening and formation of a 5-acetoxy-substituted 2(1H)-pyridone.

117 [Chemical reaction: see text] A series of acetoxy-substituted enyne-allenes, fused to cyclopentene

118 se (E1cB(I)) mechanism with acetoxy ester 3, acetoxy thioester 4, and mesyloxy thioester 6.

119 With moderately electron-withdrawing groups (acetoxy), we observe >90% of the perfectly folded confor