ライフサイエンスコーパス: acetoxymethyl

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1 Acetyl-L-alanyl-gamma-D-glutamyl-L-lysine]-3-acetoxymethyl-3-ceph em-carboxylic acid (compound 6), wa

2 Furthermore, the 4-acetoxymethyl-3-methoxy-4-methyl-5-trimethylsilyl-2,5-cy

3 The 4-acetoxymethyl-4-alkyl-3-trimethylsilyl-2,5-cyclohexadien

4 BAPTA is delivered to the cytoplasm as the acetoxymethyl (AM) ester BAPTA/AM, but released AM group

5 s involving bulk loading of neurons with the acetoxymethyl (AM) ester version of Cal-590, combined tw

6 The study demonstrated that Calcein acetoxymethyl (AM) proved to be a suitable dye for detec

7 pHi was recorded fluorimetrically with acetoxymethyl (AM)-loaded carboxy-SNARF-1 at either 27 o

8 rabbit ventricular myocytes loaded with the acetoxymethyl ester (AM) form of carboxy-seminaphthorhod

9 Myotubes loaded with the acetoxymethyl ester (AM) form of fluo-3 were imaged at r

10 of free cytosolic [Ca2+] ([Ca2+]c) using the acetoxymethyl ester (AM) form of indo-1 may be compromis

11 ing by cell-permeable Ca(2+) chelators [EGTA-acetoxymethyl ester (AM), 1, 2-bis(2-aminophenoxy)ethane

12 on flexible membranes and loaded with Fura-2 acetoxymethyl ester (AM).

13 rated that, like MDR1, SPGP effluxed calcein-acetoxymethyl ester (AM).

14 r esterase activity were analyzed by calcein-acetoxymethyl ester (AM)/ethidium homodimer assay.

15 + buffer, 2-aminophenol-N,N,O-triacetic acid acetoxymethyl ester (APTRA-AM, 20-40 mg/kg), on synaptic

16 inophenoxy)ethane-N,N,N',N'-tetraacetic acid-acetoxymethyl ester (BAPTA-AM) and completely eliminated

17 phenoxy)ethane-N, N, N', N'-tetraacetic acid-acetoxymethyl ester (BAPTA-AM) reduced cytosolic Ca(2+)

18 inophenoxy)ethane-N,N,N',N'-tetraacetic acid acetoxymethyl ester (BAPTA-AM), a Ca2+ chelator.

19 minophenoxy)ethane-N,N,N',N'-tetraacetate-AM acetoxymethyl ester (BAPTA-AM), cyclosporine, and inhibi

20 iniphenoxy)ethane-N,N,N',N'-tetraacetic acid acetoxymethyl ester (BAPTA-AM); and (4) after pretreatme

21 2-carboxyethyl)-5-(and-6)-carboxyfluorescein acetoxymethyl ester (BCECF-AM), that accumulates only in

22 in culture media containing 2 microM calcein-acetoxymethyl ester (calcein-AM) and 4 microM ethidium h

23 toma cells was evaluated with 4-hour calcein acetoxymethyl ester (calcein-AM) microcytotoxicity assay

24 o)-2'-O-methyladenosine-3',5'-monophosphate, acetoxymethyl ester (cpTOME) increased Socs3 expression

25 Ca2+ imaging studies using fura-2 acetoxymethyl ester (fura-2 AM) revealed that the increa

26 solic Ca2+ as measured by single-cell fura-2 acetoxymethyl ester (Fura-2) Ca2+-dependent fluorescence

27 y-2-naphthalenyl methyl phosphonic acid tris acetoxymethyl ester (HNMPA-(AM)(3)) inhibitor diminished

28 Here, we show that NAADP acetoxymethyl ester (NAADP-AM), a cell-permeant NAADP an

29 pig cardiac myocytes were loaded with rhod-2-acetoxymethyl ester (rhod-2 AM), and [Ca2+]c was monitor

30 nt pH indicator carboxy seminaphtorhodafluor acetoxymethyl ester acetate, we measured pH(c) in the ce

31 In particular, Sulfidefluor-7 acetoxymethyl ester allows for direct, real-time visuali

32 nophenoxy)ethane-N,N,N', N'-tetraacetic acid acetoxymethyl ester also inhibited cytokine TNFalpha-ind

33 nophenoxy)ethane-N,N,N', N'-tetraacetic acid acetoxymethyl ester and EGTA acetoxymethyl ester and the

34 etraacetic acid acetoxymethyl ester and EGTA acetoxymethyl ester and the Ser/Thr phosphatase inhibito

35 , cell survival was quantified using calcein-acetoxymethyl ester compound and a fluorescent plate rea

36 d into arterioles by pre-incubation with the acetoxymethyl ester derivative.

37 th the sodium-binding bezofuran isophthalate acetoxymethyl ester fluorescence indicator.

38 )](i)), acini were incubated in fura-2 tetra-acetoxymethyl ester for 60 minutes at 22 degrees C, and

39 ent by buffering intracellular Ca2+ with the acetoxymethyl ester form of BAPTA (BAPTA AM).

40 ing by noradrenaline, OAG, PDBu, CPA and the acetoxymethyl ester form of BAPTA (BAPTA-AM) was markedl

41 of SOC activity evoked by either CPA or the acetoxymethyl ester form of BAPTA (BAPTA-AM).

42 ously cannot be attributed to the use of the acetoxymethyl ester form of fura-2 to report [Ca2+]i, an

43 of 2.2 micron in which the membrane permeant acetoxymethyl ester form of fura-2 was used.

44 ated from ferret or cat were loaded with the acetoxymethyl ester form of indo-1 (indo-1 AM) such that

45 ccomplished by incubating the cells with the acetoxymethyl ester forms (benz2 AM or BAPTA AM).

46 2-aminophenoxy)ethane-N,N,N',N'-tetraacetate/acetoxymethyl ester has similar effects to water immersi

47 inositol-1,4,5-trisphosphate (IP(3)) hexakis acetoxymethyl ester having an ortho-nitroveratryl photoc

48 O-methyladenosine 3',5'-cyclic monophosphate acetoxymethyl ester mimicked all butaprost effects.

49 erved when the fibers were preincubated with acetoxymethyl ester of 1,2-bis (2-amino-phenoxy) ethane

50 ngendorff perfused rabbit hearts loaded with acetoxymethyl ester of 1,2-bis(2-amino-5,6-difluoropheno

51 but not by calcium chelation with BAPTA-AM (acetoxymethyl ester of BAPTA) (75 microM for 30 min), su

52 xposure of the cone to the membrane-permeant acetoxymethyl ester of the Ca2+ chelator BAPTA.

53 inophenoxy)ethane-N,N,N',N'-tetraacetic acid/acetoxymethyl ester or thapsigargin.

54 Pretreatment with either EGTA acetoxymethyl ester or vitamin E resulted in a significa

55 inophenoxy)ethane-N,N,N',N'-tetraacetic acid acetoxymethyl ester produced a > 2-fold reduction in VP-

56 inophenoxy)ethane-N,N,N',N'-tetraacetic acid acetoxymethyl ester significantly decreased ET-1dependen

57 eceptor antagonists, was measured by calcein-acetoxymethyl ester staining after 3 days in culture.

58 vival rates of RGCs were measured by calcein-acetoxymethyl ester staining.

59 henoxy)ethane-N',N'-tetraacetic acid (BAPTA)-acetoxymethyl ester to buffer intracellular calcium resu

60 ith the fluorescent calcium indicator fura-2 acetoxymethyl ester to measure their intracellular Ca(2+

61 ith the fluorescent calcium indicator Fura-2 acetoxymethyl ester to measure their intracellular Ca2+

62 Application of membrane-permeant NAADP acetoxymethyl ester to PASMCs elicited a biphasic increa

63 yte-like U937 cells were labeled with fluo-3-acetoxymethyl ester to quantitate intracellular Ca2+ con

64 '-bis(2-carboxyethyl)-5,6-carboxyfluorescein-acetoxymethyl ester was used to quantitate intracellular

65 nophenoxy)ethane-N,N,N',N'-tetraacetic acid (acetoxymethyl ester) (BAPTA AM) did the opposite.

66 ethane-N,N, N',N'-tetraacetic acid tetrakis (acetoxymethyl ester) (BAPTA-AM) blocked both ERK and Ras

67 ethane-N,N,N',N'-tetra-acetic acid tetrakis (acetoxymethyl ester) (BAPTA-AM) or blockade of extracell

68 nophenoxy)ethane-N,N,N',N'-tetraacetic acid (acetoxymethyl ester) (BAPTA-AM) or the three specific ca

69 )ethane-N,N,N',N'-tetraacetic acid tetrakis (acetoxymethyl ester) (BAPTA-AM), an intracellular Ca(2+)

70 y)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester) (BAPTA-AM), leads to a dramatic red

71 )ethane-N,N,N',N'-tetraacetic acid-tetrakis (acetoxymethyl ester) (BAPTA-AM).

72 simultaneous measurements of [Ca2+]i (fluo-3-acetoxymethyl ester) and membrane currents/action potent

73 y)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester) and the phospholipase C inhibitor U

74 noxy)ethane-N,N,N',N'-tetraacetic acid tetra(acetoxymethyl ester) had no effect on the serotonin-indu

75 )ethane-N,N,N',N'-tetraacetic acid tetrakis (acetoxymethyl ester) inhibited the process by 50%.

76 y)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester) or down-regulation of CaMKII by KN-

77 y)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester) reduced cAMP levels in PC1-knock-ou

78 aminophenoxy)ethane-N,N,N,N-tetraacetic acid acetoxymethyl ester), an intracellular calcium chelator.

79 nophenoxy)ethane-N,N,N',N'-tetraacetic acid (acetoxymethyl ester), ROS scavengers, and the caspase in

80 inophenoxy)ethane-N,N,N',N'-tetraacetic acid acetoxymethyl ester), whereas activation of ERK was not

81 photo-activatable fluorophore, NPE-HCCC2/AM (acetoxymethyl ester); (ii) locally photolyzing a caged c

82 ethane-N,N,N',N'-tetraacetic acid tetrakis (acetoxymethyl ester)] treatments.

83 minophenoxy)ethaneN,N,N',N'-tetraacetic acid acetoxymethyl ester, an inhibitor of intracellular calci

84 inophenoxy)ethane-N,N,N',N'-tetraacetic acid-acetoxymethyl ester, an intracellular Ca(2+) chelator, b

85 inophenoxy)ethane-N,N,N',N'-tetraacetic acid acetoxymethyl ester, and by the guanyl cyclase inhibitor

86 oaded with the calcium indicator dye, fluo-3 acetoxymethyl ester, and fluorescence was measured by la

87 tion, cells were incubated with Fura 2 tetra acetoxymethyl ester, and intracellular [Ca(2+)] ([Ca(2+)

88 S indicators, Sulfidefluor-4, Sulfidefluor-5 acetoxymethyl ester, and Sulfidefluor-7 acetoxymethyl es

89 loaded with a calcium indicator dye, fluo-3 acetoxymethyl ester, and the fluorescence was measured b

90 smooth muscle cells were loaded with fluo-3 acetoxymethyl ester, and the fluorescence was recorded b

91 inophenoxy)ethane-N,N,N',N'-tetraacetic acid/acetoxymethyl ester, BAPTA/AM) fully inhibits intracellu

92 mitochondrial Ca(2+) uniporter, or with EGTA acetoxymethyl ester, but not with vitamin E, prevented t

93 inophenoxy)ethane-N,N,N',N'-tetraacetic acid acetoxymethyl ester, cyclopiazonic acid, and N,N,N',N'-t

94 red rat forebrain neurons loaded with indo-1 acetoxymethyl ester, KB-R7943 inhibited the reverse mode

95 Through its acetoxymethyl ester, Nmoc-DBHQ can be loaded into cells

96 lular calcium mobilization assay with fura-2 acetoxymethyl ester, peritoneal macrophages from wild-ty

97 inophenoxy)ethane-N,N,N',N'-tetraacetic acid-acetoxymethyl ester, removal of extracellular Ca(2+), th

98 inophenoxy)ethane-N,N,N',N'-tetraacetic acid-acetoxymethyl ester, the adenylate cyclase stimulant for

99 2-carboxyethyl)-5-(and-6)-carboxyfluorescein-acetoxymethyl ester, the initial rates of monocarboxylat

100 ponin or alpha-toxin the dye, loaded via its acetoxymethyl ester, was predominantly trapped in the sa

101 or-5 acetoxymethyl ester, and Sulfidefluor-7 acetoxymethyl ester, which offer the unique capability t

102 In fura-2-acetoxymethyl ester-loaded alveolar macrophages, intrace

103 Ca2+ concentration was equivalent in Fura-2 acetoxymethyl ester-loaded Q212L-alpha 16 cells compared

104 '-bis(2-carboxyethyl)-5(6)carboxyfluorescein-acetoxymethyl ester.

105 with the Ca(2+) fluorescent indicator Fura-2 acetoxymethyl ester.

106 with the fluorescent Ca(2+) indicator fluo-4 acetoxymethyl ester.

107 ]ethane-N,N,N',N'-tetraacetic acid tetrakis [acetoxymethyl ester]).

108 noxy)ethane-N,N,N',N'-tetraacetic acid tetra(acetoxymethyl) ester (BAPTA-AM) or inhibiting NO synthas

109 y)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl) ester (BAPTA-AM) or the CaM antagonist W7

110 xy) ethane-N,N,N',N'-tetraacetic acid tetra (acetoxymethyl) ester (BAPTA-AM) reduced 5-HT release.

111 noxy)ethane-N,N,N',N'-tetraacetic acid tetra(acetoxymethyl) ester (BAPTA-AM) was added in some studie

112 noxy)ethane-N,N,N',N'-tetraacetic acid-tetra(acetoxymethyl) ester (BAPTA-AM), and PI3-K inhibitor (LY

113 nophenoxy)ethane-N,N,N',N'-tetraacetic acid-(acetoxymethyl) ester (BAPTA-AM), indicating that Ca(2+)

114 y)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl) ester, 0.1 micromol/l), or by inhibiting

115 s (o-aminophenoxy) ethane-tretraacetic acid (acetoxymethyl) ester, and dantrolene, did not alter bort

116 oxy)ethane-N,N,N', N'-tetraacetic acid/tetra(acetoxymethyl) ester, protected the cells against injury

117 yl-myo-inositol 1,3, 4-trisphosphate-hexakis(acetoxymethyl) ester.

118 nophenoxy)ethane-N,N,N',N'-tetraacetic acid (acetoxymethyl) ester.

119 phenoxy)ethane-N,N,N,N',N'-tetraacetic acid (acetoxymethyl)ester (BAPTA-AM) abolished aggregation ind

120 noxy)ethane-N,N,N',N'-tetraacetic acid tetra(acetoxymethyl)ester (BAPTA-AM).

121 o-inositol 3,4,5,6-tetrakisphosphate octakis(acetoxymethyl)ester (Bt(2)Ins (3,4,5,6)P(4)/AM).

122 -8-bis-(carboxymethyl)-aminoquinoline tetra-(acetoxymethyl)ester (Quin/AM), a calcium chelator, or wi

123 nophenoxy)ethane-N,N,N',N'-tetraacetic acid (acetoxymethyl)ester.

124 enoxy)ethane-N,N,N',N'tetraacetic acid tetra(acetoxymethyl)ester.

125 nyl)-ethane-N,N,N',N'-tetraacetic acid tetra(acetoxymethyl)-ester, a chelator of intracellular Ca2+.

126 oxy)ethane-N,N,N',N'-tetraacetic acid, tetra(acetoxymethyl)-ester, a membrane-permeable calcium chela

127 xy)-ethane-N,N,N',N'-tetraacetic acid tetra-(acetoxymethyl)-ester.

128 BAPTA) or pretreatment of oocytes with BAPTA-acetoxymethyl-ester (BAPTA-AM) nearly completely prevent

129 ',7'-bis-2-carboxyethyl-5-carboxyfluorescein-acetoxymethyl-ester (BCECF).

130 The acetoxymethyl esterified sensor variant was readily take

131 amps) to validate the selectivity with which acetoxymethyl esters (AM-esters) of cAMP analogs prefere

132 he isolated fiber cells were loaded with the acetoxymethyl esters of Fluo-3 or Calcium Green-2, or wi

133 -C8-PIP3/AM and di-C12-PIP3/AM, the heptakis(acetoxymethyl) esters of dioctanoyl- and dilauroylphosph

134 , plasma membrane integrity based on calcein-acetoxymethyl fluorescence was significantly greater at

135 re tagged by uptake of one of the following: acetoxymethyl of 2',7'-bis-(2-carboxyethyl)-5-(and 6)-ca

136 oacridine conjugate of a silyl-protected bis(acetoxymethyl)phenol (bisQMP) was synthesized and evalua

137 inophenoxy)ethane-N,N,N',N'-tetraacetic acid-acetoxymethyl) prevented the CT-induced disappearance of

138 etate derivative, 5-[(acetylamino)methyl]-2-(acetoxymethyl)pyridine (37).

139 While 3'-acetoxymethyl-substituted cephalosporins are readily ava

140 Viable cells were labeled with calcein acetoxymethyl, visualized using fluorescent microscopy,

141 present series is compound 8b [(1S,3R,6S)-2-(acetoxymethyl)-(Z)-9-(3, 4-dichlorophenylmethylene)-7-az

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