ライフサイエンスコーパス: acetyl-coenzyme A

1 ylhydralazine and arylamine substrates using acetyl coenzyme A.

2 ropylbenzoate) to isobutyrate, pyruvate, and acetyl coenzyme A.

3 responsible for the binding of the cofactor acetyl coenzyme A.

4 ion of inhibitor competition with respect to acetyl coenzyme A.

5 y generating two-carbon units in the form of acetyl-coenzyme A.

6 te dehydrogenase, which converts pyruvate to acetyl-coenzyme A.

7 raction of a proton from the methyl group of acetyl-coenzyme A.

8 D375 is the base removing the proton of acetyl-coenzyme A.

9 Homocitrate synthase (acetyl-coenzyme A: 2-ketoglutarate C-transferase; E.C. 2

10 Homocitrate synthase (acetyl-coenzyme A:2-ketoglutarate C-transferase; E.C. 2.

11 nce for the posttranslational control of the acetyl coenzyme A (Ac-CoA) synthetase (AcsA) enzyme of B

12 , and arylhydrazines by acetyl transfer from acetyl-coenzyme A (Ac-CoA) and are found in many organis

13 me A synthetase (Acs) activates acetate into acetyl-coenzyme A (Ac-CoA) in most cells.

14 ures of human Naa60 (hNaa60) in complex with Acetyl-Coenzyme A (Ac-CoA) or Coenzyme A (CoA).

15 atalyze the transfer of an acetyl group from acetyl-coenzyme A (Ac-CoA) to the amine of a wide range

16 as been proposed to comprise condensation of acetyl coenzyme A (AcCoA) and glutamate semi-aldehyde to

17 etic studies of NAT2 with two acetyl donors, acetyl coenzyme A (AcCoA) and p-nitrophenyl acetate (PNP

18 re of the yeast protein Hpa2 in complex with acetyl coenzyme A (AcCoA) at 2.4 A resolution and withou

19 zyme A-S-acetyltryptamine, demonstrates that acetyl coenzyme A (AcCoA) binding is accompanied by a la

20 of the yeast histone acetyltransferase Hat1-acetyl coenzyme A (AcCoA) complex at 2.3 A resolution.

21 e (2-AF) to 2-acetylaminofluorene (2-AAF) by acetyl coenzyme A (AcCoA) dependent N-acetylation, as ve

22 Acetyl coenzyme A (AcCoA) is the central biosynthetic pr

23 NATs) catalyze an acetyl group transfer from acetyl coenzyme A (AcCoA) to arylamines, hydrazines, and

24 talyze the transfer of the acetyl group from acetyl coenzyme A (AcCoA) to the free amino group of ary

25 Acetyl coenzyme A (AcCoA) was the preferred substrate, b

26 zyme that catalyzes pyruvate's conversion to acetyl coenzyme A (AcCoA), thereby connecting these two

27 ltransferase (AANAT) in a reaction requiring acetyl coenzyme A (AcCoA).

28 Bi-substrate kinetic analysis using acetyl-coenzyme A (AcCoA) and an H3 histone synthetic pe

29 complex with inositol hexaphosphate (InsP6), acetyl-coenzyme A (AcCoA) and/or substrate Resistance to

30 Acetyl-coenzyme A (AcCoA) is a major integrator of the n

31 thase (MtIPMS) catalyzes the condensation of acetyl-coenzyme A (AcCoA) with alpha-ketoisovalerate (al

32 involved in fatty acid metabolism, including acetyl coenzyme A (acetyl-CoA) acetyltransferase (thiola

33 homodimer that catalyzes the condensation of acetyl coenzyme A (acetyl-CoA) and alpha-ketoglutarate.

34 D(+) and ferredoxin for glucose oxidation to acetyl coenzyme A (acetyl-CoA) and CO2, NADH for the red

35 lerate moiety of PHBV is the condensation of acetyl coenzyme A (acetyl-CoA) and propionyl-CoA to form

36 they instead resorb acetate, activate it to acetyl coenzyme A (acetyl-CoA) by means of the enzyme ac

37 ed regions of biotin carboxylase subunits of acetyl coenzyme A (acetyl-CoA) carboxylases.

38 of p-coumarate to p-hydroxybenzaldehyde and acetyl coenzyme A (acetyl-CoA) encoded by the couAB oper

39 thesis of the central metabolic intermediate acetyl coenzyme A (acetyl-CoA) from acetate or for gener

40 Acetyl coenzyme A (acetyl-CoA) generated from glucose an

41 Acetyl coenzyme A (acetyl-CoA) is a key metabolite at th

42 Assimilation of acetyl coenzyme A (acetyl-CoA) is an essential process i

43 Metabolic production of acetyl coenzyme A (acetyl-CoA) is linked to histone acet

44 ng of triglycerides, suggesting an increased acetyl coenzyme A (acetyl-CoA) load.

45 an alternative carbon source utilization for acetyl coenzyme A (acetyl-CoA) production and gluconeoge

46 ing differentiation in a manner dependent on acetyl coenzyme A (acetyl-CoA) production by the enzyme

47 Here we report that acetyl coenzyme A (acetyl-CoA) stimulates RNA polymerase

48 been previously shown to contain an unusual acetyl coenzyme A (acetyl-CoA) synthetase (ACS) which ca

49 oneogenesis by suppressing the expression of acetyl coenzyme A (acetyl-CoA) synthetase (Acss), leadin

50 tylation in single-cell eukaryotes relies on acetyl coenzyme A (acetyl-CoA) synthetase enzymes that u

51 d by the induction of acs, the gene encoding acetyl coenzyme A (acetyl-CoA) synthetase, leading to up

52 6 synthesizes polyhydroxybutyrate (PHB) from acetyl coenzyme A (acetyl-CoA) through reactions catalyz

53 c bacteria lack isocitrate lyase and convert acetyl coenzyme A (acetyl-CoA) to glyoxylate via a novel

54 I/II domain-containing enzyme that condenses acetyl coenzyme A (acetyl-CoA) with malonyl-acyl carrier

55 pair and is sensitive to the availability of acetyl coenzyme A (acetyl-CoA), we investigated a role f

56 inery needed to metabolize ethanolamine into acetyl coenzyme A (acetyl-CoA).

57 significantly reduced dependence on p300 and acetyl coenzyme A (acetyl-CoA).

58 300 and demonstrate that A-485 competes with acetyl coenzyme A (acetyl-CoA).

59 revisiae, enabling biosynthesis of cytosolic acetyl coenzyme A (acetyl-CoA, the two-carbon isoprenoid

60 assimilated via two reactions, conversion of acetyl-coenzyme A (acetyl coenzyme A [acetyl-CoA]) to py

61 nvolved in conversion of acetyl phosphate to acetyl-coenzyme A (acetyl-CoA) and posttranscriptionally

62 ion reaction of fatty acid biosynthesis with acetyl-coenzyme A (acetyl-CoA) as a primer, although the

63 is a period at the onset of contraction when acetyl-coenzyme A (acetyl-CoA) availability limits mitoc

64 The biosynthesis of acetyl-coenzyme A (acetyl-CoA) by acetyl-CoA synthetase

65 Acetyl-coenzyme A (acetyl-CoA) formed within the plastid

66 e survival of Mycobacterium tuberculosis and acetyl-coenzyme A (acetyl-CoA) is an essential precursor

67 The effect of ethanol and acetate on acetyl-coenzyme A (acetyl-coA) synthetases, which conver

68 transfer of a carboxyl group from biotin to acetyl-coenzyme A (acetyl-CoA) to form malonyl-CoA.

69 e laboratories by coupling the production of acetyl-coenzyme A (acetyl-CoA) to the acetylation of 4-a

70 In the absence of other enzymes, it binds acetyl-coenzyme A (acetyl-CoA), and catalyses the transf

71 iminates interconversion between acetate and acetyl-coenzyme A (acetyl-CoA), led to elevated basal le

72 ch encodes SREBP-1) and Acacb (which encodes acetyl coenzyme A [acetyl-CoA] carboxylase 2 [ACC2], a c

73 reactions, conversion of acetyl-coenzyme A (acetyl coenzyme A [acetyl-CoA]) to pyruvate catalyzed by

74 to 3.1-fold) in expression were observed for acetyl-coenzyme A acetyltransferase (AtoB), a probable a

75 Acetyl coenzyme A (acteyl-CoA) carboxylase (ACC) is the

76 The results suggest that acetyl coenzyme A acts as a mixed V and K type activator

77 at maps to a promoter region shared with the acetyl coenzyme-A acyl-transferase-1 (ACAA1), was associ

78 ptimized GAT variant in ternary complex with acetyl coenzyme A and a competitive inhibitor, 3-phospho

79 hat the best inhibitors are competitive with acetyl coenzyme A and an X-ray cocrystal structure revea

80 he formation of N-acetylglutamate (NAG) from acetyl coenzyme A and glutamate.

81 histone acetyltransferase 1 in complex with acetyl coenzyme A and histone H4 peptide.

82 ns possesses the enzymes required to convert acetyl coenzyme A and oxalacetate to alpha-ketoglutarate

83 leading to depletion of the energy substrate acetyl coenzyme A and the antioxidant glutathione.

84 hermautotrophicus PpcA was not influenced by acetyl coenzyme A and was about 50 times less sensitive

85 active protein with a decreased affinity for acetyl coenzyme A and with a Km >10-fold that of the wil

86 l-lysine biosynthesis in fungi by condensing acetyl-coenzyme A and 2-oxoglutarate to form 3R-homocitr

87 catalyzes the condensation of glyoxylate and acetyl-coenzyme A and hydrolysis of the intermediate to

88 , usually involve incubation of radiolabeled acetyl-coenzyme A and malonyl-acyl carrier protein (MACP

89 Concentrations of acetyl-coenzyme A and nicotinamide adenine dinucleotide

90 pendent biosynthetic reaction which produces acetyl-coenzyme A and oxaloacetate from citrate and coen

91 ority of isoleucine was instead derived from acetyl-coenzyme A and pyruvate, possibly via the citrama

92 Isothermal titration studies of acetyl-coenzyme A and tobramycin binding to mutant forms

93 of 280 mM for L-glutamine and 150 microM for acetyl-coenzyme A and with a k(cat) value of 200 min(-1)

94 The K(m) apparent values for ATP, acetyl-coenzyme A, and BCCP were estimated to be 60+/-14

95 not properly activate either oxaloacetate or acetyl-coenzyme A, and the condensation reaction is over

96 lyzes the acetylation of zwittermicin A with acetyl coenzyme A as a donor group, suggesting that ZmaR

97 tion of glucose to ethanol with pyruvate and acetyl coenzyme A as intermediates.

98 rm UDP-N,N'-diacetylbacillosamine, utilizing acetyl-coenzyme A as the acetyl group donor.

99 relative concentrations of acetyl phosphate, acetyl coenzyme A, ATP, and GTP over the course of the e

100 The activities of two novel enzymes, acetyl-coenzyme A:benzylalcohol acetyltransferase (BEAT)

101 Mutagenesis of a putative acetyl coenzyme A binding site produced a TAF(II)250 pro

102 udy was to define the region responsible for acetyl coenzyme A binding.

103 H274 hydrogen bonds to the carbonyl of acetyl-coenzyme A but also forms the back wall of the ox

104 , and some bacteria, IPP is synthesized from acetyl coenzyme A by the mevalonate pathway.

105 lex stimulates the conversion of pyruvate to acetyl-coenzyme A by the pyruvate dehydrogenase complex.

106 ption from the housekeeping promoter for the acetyl coenzyme A carboxylase (ACC) gene, which encodes

107 eed in cellulo and could be used to identify acetyl coenzyme A carboxylase (ACC) in Pseudomonas aerug

108 reased AMP-activated protein kinase (AMPK)-->acetyl coenzyme A carboxylase (ACC) phosphorylation and

109 the low-density lipoprotein (LDL) receptor, acetyl coenzyme A carboxylase (ACC), and fatty acid synt

110 Escherichia coli acetyl coenzyme A carboxylase (ACC), the first enzyme of

111 tion in muscle by inhibiting the activity of acetyl coenzyme A carboxylase (ACC).

112 via its phosphorylation and inactivation of acetyl coenzyme A carboxylase (ACC).

113 tty acid biosynthesis in yeast; ACC1 encodes acetyl coenzyme A carboxylase (Acc1), and FAS1 encodes t

114 T cell-specific deletion of acetyl coenzyme A carboxylase 1 (ACC1), an enzyme that c

115 ranscription factor 1c, fatty acid synthase, acetyl coenzyme A carboxylase 2, and carnitine palmitoyl

116 or miR-204-5p which was predicted to inhibit acetyl coenzyme A carboxylase beta, a key fatty acid oxi

117 ceded by the accumulation of plastid-encoded acetyl Coenzyme A carboxylase D proteins accounting for

118 ary electrophoretic (CE) assay for measuring acetyl coenzyme A carboxylase holoenzyme (holo-ACC) acti

119 horylation of AMPK and its downstream target acetyl coenzyme A carboxylase in response to estradiol (

120 atory element binding protein 1c), and ACACA(acetyl coenzyme A carboxylase) was not different between

121 naling to AMPK substrates, including Raptor, acetyl coenzyme A carboxylase, and PGC-1alpha, is attenu

122 protein of the biotin-dependent carboxylase, acetyl coenzyme A carboxylase.

123 nthesis, acting primarily on the activity of acetyl coenzyme A carboxylase.

124 Acetyl-coenzyme A carboxylase (ACC) catalyzes the first

125 s of fatty acids, cells are endowed with two acetyl-coenzyme A carboxylase (ACC) systems.

126 protein contents of fatty acid synthase and acetyl-coenzyme A carboxylase (ACC), reduced ACC phospho

127 in part by phosphorylating and inactivating acetyl-coenzyme A carboxylase (ACC), the rate-limiting e

128 on of AMPK and its downstream target phospho-acetyl-coenzyme A carboxylase (ACC).

129 The plastid acetyl-coenzyme A carboxylase (ACCase) catalyzes the fir

130 arboxyl carrier protein isoform 2 (BCCP2) in acetyl-coenzyme A carboxylase (ACCase) function and fatt

131 ns of commercial rates (375 g ha(-1)) of the acetyl-coenzyme A carboxylase (ACCase) inhibiting herbic

132 Bacterial acetyl-coenzyme A carboxylase (ACCase) is a multicompone

133 Acetyl-coenzyme A carboxylase (ACCase) is a promising ta

134 Acetyl-coenzyme A carboxylase (ACCase) occurs in at leas

135 ase subunit of the heteromeric chloroplastic acetyl-coenzyme A carboxylase (ACCase) of Arabidopsis th

136 d nuclear gene (ACC2) that targets homomeric acetyl-coenzyme A carboxylase (ACCase) to plastids.

137 carrier protein 2 (BCCP2) inhibited plastid acetyl-coenzyme A carboxylase (ACCase), resulting in alt

138 ls are not sufficient to support heteromeric acetyl-coenzyme A carboxylase activity at a level that i

139 a1 and alpha2 AMPK activity are elevated and acetyl-coenzyme A carboxylase activity is decreased in t

140 CA inhibitors did not affect acetyl-coenzyme A carboxylase activity or total storage

141 downstream targets including phosphorylated acetyl-coenzyme A carboxylase and carnitine palmitoyltra

142 erodimer with the biotin acceptor protein of acetyl-coenzyme A carboxylase and catalyzes posttranslat

143 hosphorylation of downstream target of AMPK, acetyl-coenzyme A carboxylase and inhibition of p70S6 ki

144 ic carbon inside plastids for utilization by acetyl-coenzyme A carboxylase and the fatty acid synthes

145 The heteromeric acetyl-coenzyme A carboxylase catalyzes the first and co

146 l in natural environments, where heteromeric acetyl-coenzyme A carboxylase encoded in part by the chl

147 Plastidial acetyl-coenzyme A carboxylase from most plants is a mult

148 med for the L-type pyruvate kinase, S14, and acetyl-coenzyme A carboxylase genes.

149 S Ser633 was able to compete with Ser1177 or acetyl-coenzyme A carboxylase Ser79 for AMPKalpha phosph

150 plicated nuclear gene that targets homomeric acetyl-coenzyme A carboxylase to plastids, where the mul

151 carboxyl-carrier subunit of the heteromeric acetyl-coenzyme A carboxylase was isolated and sequenced

152 Saccharomyces cerevisiae ACC1 gene (encoding acetyl-coenzyme A carboxylase), which has three Gal4 bin

153 well as increased Ser(92) phosphorylation of acetyl-coenzyme A carboxylase, a downstream target of AM

154 tations in ACC2, encoding a plastid-targeted acetyl-coenzyme A carboxylase, cause hypersensitivity to

155 sphorylation of the AMPK substrates, p53 and acetyl-coenzyme A carboxylase, changes that correlated w

156 ased phosphorylation of both AMPK-Thr172 and acetyl-coenzyme A carboxylase-Ser79, a downstream enzyme

157 NDI-010976, an allosteric inhibitor of acetyl-coenzyme A carboxylases (ACC) ACC1 and ACC2, redu

158 Acetyl-coenzyme A carboxylases (ACCs) are required for t

159 Acetyl-coenzyme A carboxylases (ACCs) have crucial roles

160 Acetyl-coenzyme A carboxylases (ACCs) have crucial roles

161 nobiotics and/or endogenous substrates using acetyl coenzyme A (CoA) as a cofactor.

162 aretil (OG) is a small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC), the enzyme th

163 A multisubunit form of acetyl coenzyme A (CoA) carboxylase (ACCase) from soybea

164 protein kinase (AMPK) levels, and diminished acetyl coenzyme A (CoA) carboxylase phosphorylation than

165 CO dehydrogenase/acetyl coenzyme A (CoA) synthase and pyruvate oxidoreduc

166 t this phenotype is due to altered fluxes of acetyl coenzyme A (CoA), a major intermediate in C(1), C

167 Acetyl coenzyme A (CoA), malonyl-CoA, adenosine triphosp

168 Pharmaceutical inhibition of acetyl-coenzyme A (CoA) carboxylase (ACC), a key fatty a

169 Plastidic acetyl-coenzyme A (CoA) carboxylase (ACCase) catalyzes t

170 ntrast, haloxyfop, an inhibitor of cytosolic acetyl-coenzyme A (CoA) carboxylase, inhibited only elon

171 , which in turn is decarboxylated to produce acetyl-coenzyme A (CoA) for various biosynthetic purpose

172 erase catalyzes the reversible conversion of acetyl-coenzyme A (CoA) into acetylcarnitine.

173 Acetyl-coenzyme A (CoA) is used in the cytosol of plant

174 raction of both the cellular glycine and the acetyl-coenzyme A (CoA) needed for SAM synthesis.

175 Acetyl-coenzyme A (CoA) synthetase (Acs) is an enzyme ce

176 utant that has a disruption in the plastidic acetyl-coenzyme A (CoA) synthetase (ACS; At5g36880) gene

177 se (AcuC), which may control the activity of acetyl-coenzyme A (CoA) synthetase (AMP-forming, AcsA) i

178 f a member of this adenylate-forming family, acetyl-coenzyme A (CoA) synthetase, was determined in co

179 efective in a pathway involved in converting acetyl-coenzyme A (CoA) to glyoxylate (the ethylmalonyl-

180 at YopJ acted as an acetyltransferase, using acetyl-coenzyme A (CoA) to modify the critical serine an

181 rase (Pta) that converts acetyl-phosphate to acetyl-coenzyme A (CoA), led to the inhibition of RpoS a

182 lace in mitochondria to generate glycine and acetyl-coenzyme A (CoA), with glycine facilitating one-c

183 one of two cytosolic enzymes that synthesize acetyl-coenzyme A (CoA).

184 ovides at least 90% of precursors of plastid acetyl-coenzyme A (CoA).

185 n, a process that requires the generation of acetyl-coenzyme A (CoA).

186 hat mediates extensive interactions with the acetyl-coenzyme A cofactor, and structurally divergent N

187 The structure of the SSAT-spermine-acetyl-coenzyme A complex suggested that Tyr140 acts as

188 gest that sugar mobilization from glucose to acetyl-coenzyme A [corrected] is a collaboration between

189 -2, Idd3 candidate gene, CTLA-4, NRAMP1, and acetyl-coenzyme A dehydrogenase, long-chain (ACADL) (can

190 ays for acetyltransferase activity with [14C]acetyl coenzyme A demonstrated that ZmaR catalyzes the a

191 tion of the response regulator CpxR and (ii) acetyl coenzyme A-dependent acetylation of the alpha sub

192 orms of methionine, which MddA detoxifies by acetyl coenzyme A-dependent acetylation.

193 on from nucleosomal templates in vitro in an acetyl coenzyme A-dependent fashion.

194 n by the VP16 acidic activation domain in an acetyl coenzyme A-dependent manner.

195 Furthermore, we demonstrate that STAGA has acetyl coenzyme A-dependent transcriptional coactivator

196 ation is catalysed by the receptor-modifying acetyl coenzyme-A-dependent O-acetyltransferase encoded

197 e complex (PDHc), which converts pyruvate to acetyl coenzyme A, enables E. coli to resist these antim

198 In contrast to acetyl-coenzyme A, enzymatically synthesized acetyl-ACPs

199 rom the A-cluster, but it did inhibit the CO/acetyl-coenzyme A exchange activity, probably by causing

200 The bisubstrate analogue, N1-spermine-acetyl-coenzyme A, exhibited linear, competitive inhibit

201 d nitrogen sources for protein synthesis and acetyl-coenzyme A for cytosol-localized fatty acid elong

202 glutamine-derived citrate provides both the acetyl-coenzyme A for lipid synthesis and the four-carbo

203 lutamine-derived carbon produces citrate and acetyl-coenzyme A for lipid synthesis, which is required

204 ribosome binding sites for both the upstream acetyl coenzyme A formation and fatty acid synthase modu

205 was re-cast into three modules: the upstream acetyl coenzyme A formation module; the intermediary ace

206 hetase-1 (AceCS1) catalyzes the synthesis of acetyl coenzyme A from acetate and coenzyme A and is tho

207 diates arises due to the formation of [1-13C]acetyl coenzyme A from the labeled pyruvate, formed via

208 -coenzyme A, a sulfur-less, ketone analog of acetyl-coenzyme A, in its ternary complex with oxaloacet

209 ompanied by increased (14) C-glucose-derived acetyl-coenzyme A incorporation into sterols for fecal e

210 atalyzed by an apparent alpha(4)beta(4)-type acetyl coenzyme A-independent pyruvate carboxylase (PYC)

211 he transcriptional activity of p300 requires acetyl coenzyme A, indicating that it functions as a his

212 Acetyl coenzyme A inhibited the autokinase activity of P

213 o-gene operon responsible for the acetate<-->acetyl coenzyme A interconversion.

214 on, and it encodes enzymes for conversion of acetyl coenzyme A into butanol and butyrate.

215 roduced by PDH can be used for conversion of acetyl coenzyme A into reduced fermentation products, li

216 ivity of pyruvate dehydrogenase, which feeds acetyl-coenzyme A into the FAS II pathway.

217 Acetyl coenzyme A is an activator, and GarA, a forkhead

218 A steady state kinetic study showed that acetyl-coenzyme A is as efficient an ACPS substrate as c

219 We further show that glutamine-derived acetyl-coenzyme A is used for histone acetylation, where

220 histone acetylation, whereas glucose-derived acetyl-coenzyme A is used to acetylate amino sugars.

221 nsistent with this hypothesis, intracellular acetyl coenzyme A levels rose during growth in the prese

222 tion of N-acetylglutamate from glutamate and acetyl-coenzyme A, nor (detectably) the hydrolysis of N-

223 ary proton transfer from the methyl group of acetyl-coenzyme A only poorly, a process which occurs in

224 ructures of PglD in the presence of citrate, acetyl coenzyme A, or the UDP-4-amino-sugar were solved.

225 ic pathway for synthesis of fatty acids from acetyl-coenzyme A, or de novo lipogenesis (DNL), is pres

226 ays, such as the Calvin cycle, the reductive acetyl coenzyme A pathway, and the 3-hydroxypropionate c

227 eristics and in vivo rescue potential of the acetyl-Coenzyme A precursor S-acetyl-4'-phosphopantethei

228 Tricarboxylic acid acetyl coenzyme A production and ATP production were red

229 suggest that PDH is involved in most or all acetyl coenzyme A production in B. subtilis under anaero

230 The shift away from acetyl coenzyme A production toward carbon influx via an

231 nzyme activity, contributed significantly to acetyl-coenzyme A production.

232 30 microm for its substrates glyoxylate and acetyl coenzyme A, respectively, and was inhibited by br

233 is directly dependent on metabolites such as acetyl-coenzyme A, S-adenosylmethionine, and NAD+, among

234 NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system, thus l

235 The acetyl coenzyme A synthase (ACS) enzyme plays a central

236 kA) genes while downregulating expression of acetyl coenzyme A synthase (acs).

237 he proposed organonickel intermediate in the acetyl coenzyme A synthase catalytic cycle.

238 In vivo expression of CO dehydrogenase/acetyl coenzyme A synthase in Methanosarcina spp. is coo

239 a protein-based model for the NiP center of acetyl coenzyme A synthase using a nickel-substituted az

240 ial redox (hydrogenases and CO dehydrogenase/acetyl coenzyme A synthase), they have never been associ

241 a genetics-based method is used to truncate acetyl-coenzyme A synthase from Clostridium thermoacetic

242 is activity of the isolated alpha subunit of acetyl-coenzyme A synthase/carbon monoxide dehydrogenase

243 educe CO2 to acetate via the Wood-Ljungdahl (acetyl coenzyme A synthesis) pathway.

244 nsgenic hearts, despite similar fractions of acetyl-coenzyme A synthesis from palmitate and oxygen us

245 yruvate dehydrogenase complex contributed to acetyl-coenzyme A synthesis from pyruvate, and their act

246 ranscription into the adjacent gene encoding acetyl coenzyme A synthetase (acs), is overlapping and d

247 AcuA controls the activity of acetyl coenzyme A synthetase (AcsA; EC 6.2.1.1) in this

248 sible for the acetylation of the AMP-forming acetyl coenzyme A synthetase (SacAcsA, SACE_2375).

249 ation levels of metabolic enzymes, including acetyl coenzyme A synthetase 2.

250 in p-cymene catabolism; and cymE encodes an acetyl coenzyme A synthetase whose role in this pathway

251 The reaction was catalyzed by the action of acetyl coenzyme A synthetase, inorganic pyrophosphatase,

252 Acetyl coenzyme A synthetase-1 (AceCS1) catalyzes the sy

253 Acetyl-coenzyme A synthetase (Acs) activates acetate int

254 Acetyl-coenzyme A synthetase (ACS) belongs to the family

255 te Salmonella enterica, the metabolic enzyme acetyl-coenzyme A synthetase (Acs) is regulated by a Sir

256 the activity of the central metabolic enzyme acetyl-coenzyme A synthetase (Acs).

257 Acetyl-coenzyme A synthetase catalyzes the two-step synt

258 Although many Archaea have AMP-Acs (acetyl-coenzyme A synthetase) and ADP-Acs, the extant me

259 acs encodes acetyl-coenzyme A synthetase, a high-affinity enzyme tha

260 , encoding alpha-amylase, and acsA, encoding acetyl-coenzyme A synthetase, and normal activation of a

261 termined that csrA positively regulates acs (acetyl-coenzyme A synthetase; Acs) expression and isocit

262 SUR-5 also has some sequence similarity to acetyl coenzyme A synthetases and is predicted to contai

263 of unknown function; PrpE showed homology to acetyl coenzyme A synthetases.

264 ase steps along with the ultimate product of acetyl-coenzyme A that can be further oxidized for ATP s

265 he TCA cycle for the generation of cytosolic acetyl-coenzyme A that can be used for fatty acid and ch

266 ate formate lyase cannot convert pyruvate to acetyl coenzyme A, the required precursor for acetate an

267 nase, which is involved in the conversion of acetyl coenzyme A to acetate, is induced when cells are

268 ndently of the TCA cycle, direct cleavage of acetyl coenzyme A to CO and 5,10-methyl tetrahydrofuran

269 ethylotrophs to effect the net conversion of acetyl coenzyme A to glyoxylate.

270 on the mevalonate pathway for conversion of acetyl coenzyme A to isopentenyl diphosphate.

271 CC1), an enzyme that catalyzes conversion of acetyl coenzyme A to malonyl coenzyme A, a carbon donor

272 talyzes the transfer of an acetyl group from acetyl coenzyme A to polyamines such as spermidine and s

273 talyzes the transfer of an acetyl group from acetyl coenzyme A to the C3 hydroxyl moiety of several t

274 stead, LDHA maintains high concentrations of acetyl-coenzyme A to enhance histone acetylation and tra

275 oreductase responsible for the conversion of acetyl-coenzyme A to ethanol during fermentative growth.

276 sm pathways suggested that a perturbation of acetyl coenzyme A turnover was the cause of decreased Ph

277 oxidation of CO to CO2 and the synthesis of acetyl-coenzyme A, utilizing two novel Ni-Fe-S active si

278 tography and mass spectrometry verified that acetyl-coenzyme A was the product of the reaction.

279 onents for their mission: E1 and E2 generate acetyl-coenzyme A, whereas the FAD/NAD(+)-dependent E3 p

280 conversion of indole-3-pyruvate to indole-3-acetyl-coenzyme A, which is a potential precursor of IAA

281 2, 53 +/- 2, and 84 +/- 7%, respectively, of acetyl-coenzyme A while the rate of anaplerotic substrat

282 generation of the enol(ate) intermediate of acetyl-coenzyme A, while main-chain hydrogen bonds and b

283 minant enzyme catalyzing the condensation of acetyl coenzyme A with malonyl-ACP in P. aeruginosa.

284 FO), which decarboxylates pyruvate and forms acetyl-coenzyme A with concomitant reduction of low-pote

285 ed two independent production mechanisms for acetyl-coenzyme A with different biological functions.

286 to catalyze the condensation of pyruvate and acetyl coenzyme A, with the formation of (R)-citramalate