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1 ipids in Archaea but is dephosphorylated and acetylated.
2 howed that RhoGDIalpha is extensively lysine-acetylated.
3 sted that 1-pyrroline might be enzymatically acetylated.
4 6, K9, and K15) in Nt(17) were significantly acetylated.
5 Here, we report that the TUG C terminus is acetylated.
6 f the mature effector was found likely to be acetylated.
7 eta-MHC isoforms were found to be reversibly acetylated.
8 rged exopolysaccharide composed of partially acetylated 1-->4 glycosidic linkages of N-acetylgalactos
10 can act independently to posttranslationally acetylate a distinct set of substrates, notably actin.
11 acetylase) and therefore cannot N-terminally acetylate a majority of normally N-terminally acetylated
18 ves to the basal side and become extensively acetylated after the duplicated centrosomes reposition t
19 e treatment of control mitochondria with the acetylating agent acetic anhydride inhibits pyruvate upt
22 mini that are devoid of methionine and Naa50 acetylates all other peptides that are followed by methi
23 which is composed of nonstoichiometrically O-acetylated alpha-1,4-linked N-acetylgalactosaminuronic a
25 so aimed to explore a potential mechanism of acetylated alpha-tubulin (alpha-Ac-Tub) regulation by Ac
28 fferentiation was demonstrated via increased acetylated alpha-tubulin and SOX9 proteins, the number o
32 om the slightly higher helical propensity of acetylated-alphaS in solution leading to a more homogeno
33 er effects of triacetylresveratrol (TRES, an acetylated analog of RES) which has higher bioavailabili
35 f autophagy initiation and flux by affecting acetylated and dynamic microtubules in a reciprocal way.
37 s heparin and heparan sulfate occurring in N-acetylated and N-sulfated forms, and as the unmodified a
38 In Loxl3-/- mice, Stat3 is constitutively acetylated and naive CD4(+) T cells are potentiated in T
40 Here, we show that mitochondrial GOT2 is acetylated and that deacetylation depends on mitochondri
41 Here, we report that both ERK1 and -2 are acetylated and that HDAC6 promotes ERK1 activity via dea
42 y examining the N-terminal sequences of many acetylated and unacetylated proteins and more recently b
44 owever, whether other regions of MSH2 can be acetylated and whether other histone deacetylases (HDACs
45 misfolded variants of cytosolic enzymes that acetylate arylamines and ubiquitinate proteins, respecti
49 ctivity, lowered levels of total tau and tau acetylated at K174, rescued tau-induced memory deficits
50 s of histone H3 and of the BRD domain for H3 acetylated at Lys(14) (H3K14ac), the exact mode of H3 bi
51 -mediated association to histone H3 peptides acetylated at lysine 14 (H3K14Ac), validating the import
53 cells to high glutamine concentration, GS is acetylated at lysines 11 and 14, yielding a degron that
54 due to a deletion in wciG Serotype 35C was O-acetylated at the 5- and 6-positions of 3-beta-galactofu
55 DNA damage the acetyltransferase Tip60 must acetylate ATM proteins prior to their full activation by
56 Two glycoclusters constituted by four fully acetylated beta-acetylmannosamine residues linked throug
59 s of a canonical nucleosome, is specifically acetylated by p300 in prenucleosomes relative to nucleos
61 tylation by TIP60, while this residue can be acetylated by TIP60 in vivo, blocking its ubiquitylation
67 ding of BRD2 to H4Ac protects the underlying acetylated chromatin from attack by histone deacetylases
74 served primer-template looped structure, its acetylated counterpart uses a different mechanism, one c
77 ty of tyrosol (T), resveratrol (R) and their acetylated derivatives (AcD), as increased lipophilicity
79 ntained the greatest relative abundance of O-acetylated derivatives, Binocrit expressed the least Neu
80 low amylose rice starches, whether native or acetylated, did not form films with desirable characteri
87 we observed elevated levels of CIDEC and its acetylated form in HDAC-deficient adipocytes as well as
88 omain readers, which preferentially bind the acetylated forms of their cognate ligands, the acidic do
90 for HDAC8-catalyzed deacetylation of singly-acetylated, full-length protein substrates, revealing th
91 , an l-histidine methyl ester linker, and an acetylated galactose bonded to one of the aromatic nitro
92 The hydrolysis occurs at sites with fully acetylated GlcNAc moieties, with preference for uncross-
93 vity and led to increased GRP78 acetylation; acetylated GRP78 then bound to VPS34, a class III phosph
94 action was anthocyanin compounds, especially acetylated>diglucosylated forms than glucosylated ones.
97 Intriguingly, the accumulation of lysine 5-acetylated H2B was cell age-dependent and was associated
99 vealed a significantly higher association of acetylated H3 and H4 with the E-cadherin promoter in kid
101 nscription, associated with an enrichment of acetylated H3 at several sites of Bdnf promoter I, more
102 termine that non-canonical histone signature acetylated H3 lysine 23 (H3K23ac)-binding protein tripar
103 decreased expression of Bcl-xL and increased acetylated H3, reversing the expression patterns observe
105 articles (NCPs) containing site-specifically acetylated H3K14 or H3K56 and measured repair of uracil
107 find that the SAGA HAT module preferentially acetylates H3K4me3 nucleosomes in a mixture containing e
109 NuRD transcriptional repressor complex to de-acetylate H3K9 and repress RNA polymerase II recruitment
111 of unacetylated, mono-, di-, tri-, and tetra-acetylated H4 histone tails using Replica Exchange Molec
113 ncreased levels of acetylated pRb as well as acetylated H4K16 both globally and at telomeric regions.
114 e PU.1 promoter in progenitor cells, whereas acetylated HDAC1, which is inactive, is on the silenced
118 rait loci, disease-associated polymorphisms, acetylated histone 3 lysine 27 (H3K27ac) and transcripti
119 -methylated histone 3 lysine 4 (H3K4me3) and acetylated histone 3 lysine 9 (H3K9ac) at the HER2 promo
120 additional repressive histone modifications, acetylated histone 3 on lysine 9 and 14 deacetylation, a
122 y by sodium butyrate enhances recruitment of acetylated histone 3 to the IL-10 promoter and increases
123 rified the increased enrichment of lysine-27 acetylated histone H3 at discrete loci, accompanied by e
127 quencing analyses revealed that ENL binds to acetylated histone H3, and co-localizes with H3K27ac and
129 m molecular dynamics simulations of a doubly acetylated histone H4 peptide bound to the bromodomain o
130 fashion, selective disruption of bromodomain:acetylated histone interactions with chemical probes ser
132 teins (BET) are chromatin adapters that bind acetylated histone marks via two tandem BDs, BD1 and BD2
133 ET proteins to chromatin by engaging cognate acetylated histone marks, and the extraterminal (ET) dom
137 1 alters the direct association of BRD4 with acetylated histone-packaged promoters and reduces the tr
138 em in Drosophila, regulates gene activity by acetylating histone H4 preferentially at lysine 16.
139 gulator that localizes to DNA via binding to acetylated histones and controls the expression of thera
140 nal domain (BET) protein family, which binds acetylated histones and is a critical regulator of trans
141 of BRD4, a bromodomain protein that binds to acetylated histones and is a key transcriptional coactiv
142 eins are epigenetic "readers" that recognize acetylated histones and mark areas of the genome for tra
143 " proteins (BRD2, BRD3, BRD4, and BRDT) bind acetylated histones and serve as a scaffold for the recr
144 cetylated H4 decreases in late spermatids as acetylated histones are removed from the condensing nucl
145 n spermatids revealed enrichment of BRD4 and acetylated histones at the promoters of active genes.
147 l (BET) proteins are epigenetic "readers" of acetylated histones in chromatin and have been identifie
148 es the Adipoq gene by recruiting P-TEFb onto acetylated histones in the transcribed region of the gen
150 dues in histone H3 enables deposition of pre-acetylated histones into cellular chromatin, via a pathw
151 t indicating that SEC recruitment to certain acetylated histones on a subset of genes stimulates the
152 the interaction between its YEATS domain and acetylated histones reduces the ATAC complex-dependent p
153 -forward loops of acetylation and binding of acetylated histones that drive transcription of underlyi
155 ecialized binding modules that interact with acetylated histones, linking chromatin recognition to ge
156 T) proteins, inhibiting them from binding to acetylated histones, which occurs preferentially at supe
163 oxylic acid cycle, has been identified to be acetylated in bacteria by proteomic studies, but no furt
166 including the histone acetyltransferase p300 acetylated in its activation loop, which could explain s
168 we discover that RhoGDIalpha is endogenously acetylated in mammalian cells, and we identify CBP, p300
171 considered that long-lived microtubules are acetylated inside their lumen and that microtubule acety
172 that the AXY9 protein may act to produce an acetylated intermediate that is part of the O-acetylatio
174 ing in the induction of P300 which, in turn, acetylates IRS1/2, inhibits its association with the ins
175 nd muscle Arnt-like protein), CLOCK directly acetylates K165 and K176 of argininosuccinate synthase (
176 s modified forms of LDL, such as oxidized or acetylated LDL, and promotes ingestion by macrophages in
180 ly, recent reports claim that Naa10 may also acetylate lysine residues of diverse targets, including
182 nalysis of DNA methylation, histone marking (acetylated lysine 9 in histone H3 and trimethylated lysi
183 ivity of the mammalian sirtuin SIRT7 targets acetylated lysine in the N-terminal tail of histone H3 (
184 omains, small protein modules that recognize acetylated lysine on histones, play a significant role i
189 es 18 enzymes that catalyze deacetylation of acetylated lysine residues; however, the specificity and
190 e interaction between BET proteins and their acetylated lysine substrates may provide a new therapeut
193 ac (histone H3, phosphorylated serine 10 and acetylated lysine-14), H3K4me3 (histone H3, trimethylate
195 by mass spectrometry analysis, identifying 4 acetylated lysines in 3 distinct functional domains.
197 tandem bromodomains that mediate binding to acetylated lysines on target proteins to regulate gene e
198 JQ1, which blocks the functional readout of acetylated lysines, reduced heroin self-administration a
202 ine acetyltransferase), Rv0998, specifically acetylates MbtA on lysine 546, in a cAMP-dependent manne
205 chia coli deacetylase CobB could deacetylate acetylated MDH, while the E. coli acetyltransferase YfiQ
208 immunohistochemistry for SIRT3 activity via acetylated MnSOD(K68) Murine AEC SIRT3 and cleaved caspa
209 athogen KSHV, led to perinuclear wrapping by acetylated MT bundles and identified ORF52 as the viral
210 cally unlocks the nutritive potential of 9-O-acetylated mucus sialic acids for foraging by bacteria t
213 he Golgi apparatus, and has a preference for acetylating N termini of the transmembrane proteins.
214 mutant virus encoding K229R, mimicking a non-acetylated NP lysine residue, is severely impaired compa
218 2e are therefore critical for creating open, acetylated nucleosome structures and for controlling end
220 ide produced by R7A is a monomer unit of the acetylated octasaccharide with the structure (2,3/3-OAc)
221 he transcriptionally active form of the p65 (acetylated on lysine 310) subunit of NF-kappaB exclusive
224 tuin-1 and Foxo3alpha with downregulation of acetylated p53 expression and prevented downregulation o
228 y using a set of four enkephalin-related and acetylated peptides to generate 12 larger peptide sequen
229 the formation of robust and mature MurNAc O-acetylated peptidoglycan and infer its role in the divis
231 SIRT6 levels correlate with elevated nuclear acetylated PKM2 levels in increasing grades of hepatocel
233 has an allosteric polyamine-binding site and acetylating polyamines regulate their intracellular conc
234 tion of SIRT1 leading to increased levels of acetylated pRb as well as acetylated H4K16 both globally
239 differentially expressed proteins and lysine acetylated proteins were involved in a number of differe
240 cetylate a majority of normally N-terminally acetylated proteins, including Hsp90 and most of its coc
245 ates pyruvate dehydrogenase complex (PDC) by acetylating pyruvate dehydrogenase (PDH) and PDH phospha
247 alytic head we found that phosphorylated and acetylated residues are primarily on alpha/beta and beta
248 ng different interfaces the higher abundance acetylated residues are proximal to the regulatory sites
252 roup 2a CoVs, e.g., hCoV-OC43, for which 9-O-acetylated sialic acid (9-O-Ac-Sia) serves as a receptor
253 trate that hCoV-HKU1 uses certain types of O-acetylated sialic acid residues on glycoproteins to init
254 to slightly reduced retention times, while O-acetylated sialic acid-containing glycoforms are retaine
256 pends on a novel acetyltransferase domain to acetylate signalling proteins from plant and animal host
257 e natively folded, site-specific, and lysine-acetylated Sirt1-3 substrate proteins, namely Ras-relate
259 totic factors FoxO1/3 are overly degraded by acetylated Skp2, resulting in polyploid cell division, g
261 hown that SpeG is the enzyme responsible for acetylating spermidine under stress conditions and for p
262 lied raw materials, production procedures of acetylated starch and correlations between the degree of
264 soluble and insoluble complexes for the low acetylated starch, but not for the high acetylated starc
271 ndings provide new insights into the role of acetylated STAT3-mediated activation of IGF2 transcripti
272 hanistically, p300-histone acetyltransferase acetylates STAT3, which, in turn, upregulates and activa
274 aining monosaccharides, phosphorylated and N-acetylated sugars, polyols, carboxylic acids, nucleotide
275 ines and amides, primary amides, and novel N-acetylated sugars, which together account for nearly 50%
278 in AD brains, Tracy et al. (2016) found that acetylated tau promotes synaptic dysfunction through dis
280 uman Naa50 suggested the presence of CoA and acetylated tetrapeptide (AcMMXX) that have co-purified w
283 ctors including Ctf4 and Chl1, concomitantly acetylates the chromosomal cohesin complex to stabilize
285 gae T3SE HopZ1a is an acetyltransferase that acetylates the pseudokinase AtZED1 and triggers recognit
286 hed to prevent intramolecular arrangement by acetylating the N-terminal amino group prior to electroc
288 oietic maturation system driven by GATA1, an acetylated transcription factor previously shown to inte
289 n TacT contributes to persister formation by acetylating tRNA, a novel mechanism of toxin action.
291 toma lanceolatum was reinvestigated by using acetylated tubulin immunohistochemistry, which specifica
292 While ATP depletion led to cell death, over-acetylated tubulin led to inhibition of motility and mit
294 tive stimulus, we demonstrate that p66Shc is acetylated under high glucose conditions and is deacetyl
296 of the interactions between Ubc9 and its K65 acetylated variant (Ac-Ubc9K65) with three NDSMs derived
297 analysis has led to the identification of an acetylated variant of STX with unprecedented, low-nanomo
299 r cells, we demonstrate that C/EBPepsilon is acetylated, which was confirmed by mass spectrometry ana
300 the dosage compensation complex (DCC), which acetylates X chromatin in males [11], becomes mis-locali
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